NOW Supplements Taurine

l-glutamine's role in anxiety

Possibly Effective

Based on 4 Researches

Zhu J, Zhong Z, Shi L, Huang L, Lin C, et al. Gut microbiota mediate early life stress-induced social dysfunction and anxiety-like behaviors by impairing amino acid transport at the gut. Gut Microbes. 2024;16:2401939. doi:10.1080/19490976.2024.2401939

Our exploration delves into how early life stress affects anxiety and social behavior, particularly through the role of l-glutamine. We found that maternal separation in mice led to reduced levels of amino acid transporters in the gut, which in turn caused lower glutamine levels in the bloodstream. This was significant since glutamine is vital for brain functions, including the production of key neurotransmitters that influence mood and behavior.

In our findings, we noted that these low glutamine levels were linked to synaptic dysfunction in the medial prefrontal cortex, which is crucial for regulating emotional responses. Importantly, we observed that when we supplemented the mice with l-glutamine, there was noticeable improvement in their social behaviors and reduced anxiety-like symptoms. This indicates that enhancing amino acid transport through l-glutamine could be a beneficial strategy to mitigate the adverse effects of early life stress on mental health.

Overall, our research highlights a promising relationship between l-glutamine supplementation and emotional behavior improvements, pointing to a potential pathway through which gut bacteria may influence anxiety and social interactions.

Improved calmness

Most Useful Review

131 people found this helpful

Who knew so much good could come from one supplement? This is a "must-have" amino acid for anyone with anxiety or stress. I've reached a new level of calm – and I mean calm, not sedated; there's a distinction. While medications like SSRIs and benzodiazepines work, they tend to numb the issue instead of addressing it. Taking Taurine at a dose of 2-3g daily has significantly improved my mood and made me feel less "alone or depressed". It takes a few days for it to fully take effect on anxiety, and a couple of weeks for depression, but it’s worth trying.

Updated: Apr 2025

Colitis details

Effective for Colitis

12 people found this helpful

Works very well with my Colitis. I was diagnosed with Colitis and experienced soft stools almost every morning for a few months. Probiotics were initially helpful, but their effectiveness waned after travel. After adding this product, I take 2 to 3 capsules each night before bed, and my digestion has improved significantly.

Gastritis details

Significant improvement

Excellent! It's convenient to take just one pill daily. Despite suffering from gastritis and enteritis, my condition has improved significantly since using glutamine. I'm pleased with its quality, ingredients, and delivery.

13 people found this helpful

Leg Cramps details

This is undoubtedly the best supplement for leg cramps and RLS. However, I can't take it at night, as it keeps me awake. When I add taurine in the morning, it benefits my muscles significantly.

Allergies details

Glutamine enhances immune responses

Moderately Effective

Based on 2 Researches

Fan J, Wang X, Wang Y, Song J, Chen M, et al. Dietary glutamine supplementation improves both Th1 and Th17 responses via CARD11-mTORC1 pathway in murine model of atopic dermatitis. Int Immunopharmacol. 2024;143:113316. doi:10.1016/j.intimp.2024.113316

We investigated how dietary glutamine, a nutrient known to influence the immune system, impacts allergies, particularly in atopic dermatitis (AD). Our focus was on understanding the connection between glutamine and a specific protein called CARD11, which plays a crucial role in Th1 and Th17 immune responses.

In our study, we used mice that had been sensitized to house dust mites, a common trigger for allergic reactions. We found that these mice showed increased levels of certain immune markers, like interferon-gamma and interleukin-17, which are associated with allergic responses. However, when CARD11 was absent, these immune reactions were significantly diminished, highlighting CARD11's importance in managing allergic responses in AD.

Additionally, we looked at how blocking a signaling pathway linked to CARD11 influenced immune responses. Interestingly, when glutamine was added to the diet of mice lacking CARD11, we observed a restoration of those immune responses. This suggests that glutamine potentially enhances Th1 and Th17 responses through its action on the CARD11-mTORC1 pathway.

Overall, our findings suggest that glutamine supplementation could be a promising approach to improving immune responses in atopic dermatitis, opening the door for new dietary treatments for allergies.

Quickly raises immunity

Most Useful Review

6 people found this helpful

It perfectly protects against allergies. I purchased this for my mother on a doctor's recommendation, as she suffers from allergies to various blooms and certain medications. This excellent supplement is beneficial not just for athletes but for anyone! It rapidly boosts immunity, and alongside zinc and vitamin D, it can help avoid illness at the first signs. Additionally, this amino acid improves circulation and overall bodily function. I highly recommend that anyone with seasonal allergies start taking it in advance to witness the results.

Updated: Mar 2026

Bone Pain details

3 people found this helpful

Excellent product! It truly helped me with Leaky Gut Syndrome. I find it exceptional as it has alleviated my pain, indicating that my condition is healing.

111 people found this helpful

Candidiasis details

The use of glutamine is beneficial for our health, especially my gut health! It assists me in my fight against Candidiasis. I noticed a significant reduction in cravings for sweets after starting it. I now take one capsule in the morning alongside the AMC-cocktail, which maintains the balance of amino acids, and I notice its effects. It also strengthens my immunity, which has greatly improved since I had been unwell for a long time. Furthermore, it is advantageous for athletes, as my husband has found it aids in recovery and muscle gain after weight training.

2 people found this helpful

Cold Sores details

I don’t catch colds any more! I typically take one tablet a day. Having experienced the benefits of glutamine for quite some time, I no longer encounter cold sores. I used to use the powder version, but I find the capsule much easier to consume, so I've been using this format lately.

Reduced gastrointestinal issues

High Cholesterol details

11 people found this helpful

Glutamine is essential for those with sensitive stomachs! This product boasts a high concentration of L-Glutamine, aiding muscle recovery and protecting the gastrointestinal system. Since I started using this supplement, my post-workout recovery has noticeably improved, and I've significantly diminished my gastrointestinal problems. This allows me to continue training without setbacks. However, the product claims to contain taurine, which is misleading since it solely contains glutamine! If you found this review helpful, please "like" it.

Ulcer details

Lachnum polysaccharides promote ulcer healing

Moderately Effective

Based on 10 Researches

Zhang X, Liu D, Ye Z, Chen X, Chen H, et al. Gastroprotective effect of the Lachnum polysaccharide and polysaccharide-dipeptide conjugates against gastric ulcer. Food Chem Toxicol. 2023;174:113661. doi:10.1016/j.fct.2023.113661

We examined the effects of Lachnum-derived polysaccharides, specifically a modified compound known as LAG, on gastric ulcers in mice. The study involved treating mice with acute ulcers using different doses of LAG and another polysaccharide, LEP2a.

Our findings revealed that both compounds significantly reduced gastric mucosal damage and inflammation. LAG showed greater effectiveness, improving antioxidant levels and reducing harmful inflammatory markers. Essentially, these polysaccharides help protect the stomach lining by tackling oxidative stress and inflammation.

Promotes digestion

Most Useful Review

2 people found this helpful

Glutamine is an important amino acid for the digestive system. It repairs ulcers and aids in digestion and absorption, thereby reducing constipation and coughing. Additionally, it is beneficial for athletes in restoring muscle tissue following strenuous exercise. The package is substantial, offering excellent quantity for the price. It is recommended to take it between meals on an almost empty stomach and after exercise.

Updated: Mar 2026

Bloating details

Naturopathic approach shows promise

Moderately Effective

Based on 2 Researches

Pistoia JC, Chandler L. Naturopathic Approach to Functional Dyspepsia: A Case Report. Integr Med (Encinitas). 2021;20:32.

We explored the impact of various naturopathic treatments on bloating, focusing on a case involving a young female graduate student struggling with functional dyspepsia symptoms. This student presented with issues such as bloating, abdominal pain, and reflux. Rather than relying solely on conventional medications like proton pump inhibitors, a combination of treatments was utilized, including an elimination diet, apple cider vinegar, L-glutamine powder, and a homeopathic formula.

During our observation, we noted that the patient experienced significant improvement within just one week, with most symptoms resolved by the end of the month. However, it's important to mention that while L-glutamine was a part of this holistic treatment plan, the other concurrent therapies make it challenging to pinpoint its specific influence on bloating. We recognize that patient responses can vary significantly, but this case emphasizes the potential for naturopathic strategies to bring about relief from digestive discomfort, even if the exact role of L-glutamine remains unclear.

Overall, we found that naturopathic methods can lead to substantial improvements in gastrointestinal function in a relatively short time frame, providing a hopeful avenue for those suffering from similar issues.

Improved digestion

Most Useful Review

45 people found this helpful

Hello everyone! I suffer from leaky gut and food intolerance. I opted for this supplement over the pricier Thron brand. After two months at 2 grams daily, I've noticed considerable improvement. It normalised my stool, stopped bloating, and reduced food intolerance symptoms like skin reactions. I also feel a significant energy boost after taking it, and my mood lifts remarkably. I can now lift weights I couldn’t before, and my previously painful ligament feels better now.

Updated: Mar 2026

Blood Clot details

Enhanced blood circulation

It works effectively. The capsules are small and easy to swallow, and I believe they contribute positively to improving my blood circulation.

Chemotherapy details

Glutamine mouthwash reduces mucositis

Possibly Effective

Based on 4 Researches

Sankaran SS, Dewan P, Malhotra RK, Harit D, Kashyap B, et al. Glutamine Mouthwash for Preventing Methotrexate-Induced Mucositis in Children with Acute Lymphoblastic Leukemia: A Randomized Cross-Over Trial. Indian Pediatr. 2025;62:269. doi:10.1007/s13312-025-00042-4

We assessed how glutamine mouthwash stacks up against standard oral hygiene practices in kids with acute lymphoblastic leukemia undergoing high-dose methotrexate treatment.

In a randomized cross-over trial involving 64 chemotherapy courses, children received either glutamine mouthwash or usual care. We found that while both groups experienced mucositis, the glutamine group showed a significantly lower rate of severe cases, shorter duration of discomfort, and less pain overall.

This suggests that glutamine mouthwash could be a beneficial addition to chemotherapy care for reducing the impact of painful mouth sores.

Minimises mouth pain

Most Useful Review

1 people found this helpful

The doctor advises taking this during chemotherapy to prevent mouth injuries. The pills are quite large, requiring me to take ten at once, twice daily, but they are effective.

Updated: Mar 2026

Flu details

1 people found this helpful

After taking glutamine, my severe reflux esophagitis symptoms were immediately alleviated. It's beneficial for muscles, so it's the right nutrition for me. I try to consume it on an empty stomach as often as possible.

Food Poisoning details

Energy during workouts

13 people found this helpful

Excellent assistant in sports! This is my second Glutamine purchase. The first, from Solgar, had no effect. Now Foods’ Glutamine really helps me; it boosts my energy during workouts. I wake up without aches, and my muscles feel fine. I'm very pleased with the results.

I initially bought it because I heard it was beneficial during exercise, but I believe it supports brain function more than physical activity. The ingredients and effects are impressive.

Brain Tumor details

Investigating L-glutamine in CFS

Chronic Fatigue Syndrome details

Maes M, Leunis JC. Normalization of leaky gut in chronic fatigue syndrome (CFS) is accompanied by a clinical improvement: effects of age, duration of illness and the translocation of LPS from gram-negative bacteria. Neuro Endocrinol Lett. 2008;29:902.

We explored how natural anti-inflammatory and antioxidant substances like L-glutamine could affect chronic fatigue syndrome (CFS) in patients. Over a 10-14 month period, we measured immune responses and overall health in 41 CFS patients before and after treatment.

Our findings indicated that improving gut health through these substances might lead to better clinical outcomes. While the study emphasizes targeted treatments for leaky gut in CFS, we found that it’s a promising area for future research rather than a definitive cure.

Boosts energy levels

Most Useful Review

3 people found this helpful

I have found that glutamine significantly enhances my energy and alertness. I highly recommend it for anyone experiencing low energy, alertness, and focus issues due to fatigue.

Updated: Apr 2025

Liver Disease details

L-glutamine supports liver function

Questionable

Based on 2 Researches

USERS' SCORE

Good

Based on 9 Reviews

Leite JSM, Vilas-Boas EA, Takahashi HK, Munhoz AC, Araújo LCC, et al. Liver lipid metabolism, oxidative stress, and inflammation in glutamine-supplemented ob/ob mice. J Nutr Biochem. 2025;138:109842. doi:10.1016/j.jnutbio.2025.109842

We explored how L-glutamine affects liver health in ob/ob mice, specifically looking at its antioxidant and anti-inflammatory properties. Over 40 days, mice received either L-alanyl-L-glutamine or free L-glutamine, while control mice drank just water.

Our findings showed that the L-alanyl-L-glutamine group experienced improved insulin sensitivity and reduced liver fat. Although free L-glutamine raised muscle glutamine levels, it had less impact on overall insulin resistance. Ultimately, boosting glutamine levels helped mitigate oxidative stress and inflammation linked to obesity.

Detox support

Most Useful Review

9 people found this helpful

I use it with glycine, cysteine, NAC, and vitamin C to produce glutathione, acting as an antioxidant to cleanse the liver and body of toxins. If you find this review helpful, please click the Like button.

Updated: Mar 2026

Constipation details

This is remarkable for healing the digestive tract! After taking it consistently since 2019, I experienced a transformation in my long-standing constipation, going to the toilet regularly each morning without issues. Even after stopping the carnivore diet, I still encounter very few problems, and my sleep has improved as well.

Diarrhea details

Diarrhea has decreased

3 people found this helpful

I started taking glutamine to combat my weak stomach and prevent SIBO. It has worked wonders—my diarrhea has nearly vanished and my stool consistency is perfect. I believe it's beneficial for my gut health.

Autoimmune Disorder details