Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.1
USERS' SCORE
Good
Based on 17 Reviews
8.1
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Taurine (Free-Form)
1 g (1,000 mg)
*

Top Medical Research Studies

9
Taurine reduces apoptosis in diabetes
We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.

Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).

PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.

Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
Taurine aids spinal cord recovery
We explored the impact of taurine on spinal cord axon injury, particularly in the context of diabetic neuropathy, a common complication arising from diabetes mellitus. Using a rat model induced by streptozotocin—essentially a tool to mimic diabetes—we found that taurine significantly reduced axonal damage observed in the spinal cord.

Our analysis included both morphological and functional assessments, revealing that taurine not only ameliorated damage but also promoted neurite outgrowth in neurons exposed to high glucose levels. This suggests that taurine could play a beneficial role in repairing neural injuries associated with diabetes.

We also noted that taurine boosts the expression of nerve growth factor (NGF) and GAP-43, essential proteins for nerve growth and repair. The observed improvements seem linked to the activation of specific signaling pathways, namely the NGF-pAkt-mTOR axis. Interestingly, blocking this pathway with certain inhibitors dampened the positive effects of taurine, highlighting its crucial role in the protection and repair of neural tissues in diabetic conditions.

Overall, our findings indicate that taurine could be a promising therapeutic agent for enhancing spinal cord recovery from diabetic-induced injuries, providing hope for better management of diabetic neuropathy.
Read More

Most Useful Reviews

9
Nerve improvement noted
16 people found this helpful
This supplement was recommended in a book about diabetes. After ordering a small bottle and noticing a significant difference in my leg nerves, I purchased a larger one. I intend to continue using it.
Read More
9
Stabilised insulin levels
3 people found this helpful
Gorgeous drug. My mum drinks it for her diabetes, being overweight and having fatty liver. We are pleased with the results; the insulin levels in her blood have stabilised and both hepatosis and weight have decreased. The course of treatment lasts 3 to 6 months, taking two grams in the morning on an empty stomach.
Read More
7.5
Improves cardiovascular health
3 people found this helpful
Taurine is an invaluable amino acid I've been advised to use by a specialist. Its effects become noticeable after around 1-2 months and it is particularly beneficial for elderly individuals and those on bed rest. It enhances muscle energy and is highly recommended for managing type 1-2 diabetes, as well as improving arterial elasticity.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.1
  • All Researches
9.5
Intrarectal taurocholate improves diabetes markers
We explored the impact of intrarectal sodium taurocholate on hormone levels and glucose control in obese type 2 diabetic volunteers.

In a study with ten participants, we noted that higher doses of taurocholate led to significant increases in GLP-1, PYY, and insulin levels.

Remarkably, plasma glucose levels dropped, and participants consumed up to 47% less food after treatment.

This suggests that therapies boosting bile salts might help manage diabetes and obesity effectively.
Read More
9
Taurine reduces apoptosis in diabetes
We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.

Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
9
Taurine's role in diabetic wound healing
We explored the role of taurine, a naturally occurring amino acid, in healing diabetic wounds. The study developed innovative patches that combine taurine with cerium dioxide, creating a unique treatment tool designed to tackle the challenges of wound healing in diabetes.

By using microneedle technology, these patches ensure that the beneficial components penetrate deep into the wound tissue. This method enhances the effectiveness of taurine, allowing it to help reduce oxidative stress and low-level inflammation commonly associated with non-healing diabetic wounds.

Our findings revealed that these specially designed patches not only stimulate healing but also improve the overall immune environment, making it easier for the body to repair damaged tissue. Ultimately, the approach harnesses taurine's antioxidant and anti-inflammatory properties, showing promising results in facilitating wound closure in diabetic patients.

Overall, the study highlights the potential of combining taurine with advanced delivery methods in overcoming obstacles to effective diabetic wound healing.
Read More
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).

PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.

Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
Taurine aids diabetic wound healing
We delved into how taurine, paired with chitosan, can assist in healing wounds, especially in the context of diabetes. The study involved creating chitosan-taurine nanoparticles, which were then mixed into carboxymethyl chitosan hydrogels. This innovative combination aimed to enhance how well and how quickly wounds heal.

Our findings showed that these special hydrogel dressings not only supported better biodegradation and biocompatibility, but they also encouraged healing processes like angiogenesis—the formation of new blood vessels. The inclusion of taurine appears to have anti-inflammatory properties and promotes the movement and growth of cells essential for healing.

Importantly, tests on mice demonstrated that these dressings significantly improved wound healing in both acute and chronic diabetic conditions. We observed that the sustained release of taurine from the hydrogels has great potential for clinical applications in treating various types of wounds, making our study an exciting step forward in wound care.
Read More

User Reviews

USERS' SCORE
Good
Based on 17 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Nerve improvement noted
16 people found this helpful
This supplement was recommended in a book about diabetes. After ordering a small bottle and noticing a significant difference in my leg nerves, I purchased a larger one. I intend to continue using it.
Read More
9
Stabilised insulin levels
3 people found this helpful
Gorgeous drug. My mum drinks it for her diabetes, being overweight and having fatty liver. We are pleased with the results; the insulin levels in her blood have stabilised and both hepatosis and weight have decreased. The course of treatment lasts 3 to 6 months, taking two grams in the morning on an empty stomach.
Read More
7.5
Improves cardiovascular health
3 people found this helpful
Taurine is an invaluable amino acid I've been advised to use by a specialist. Its effects become noticeable after around 1-2 months and it is particularly beneficial for elderly individuals and those on bed rest. It enhances muscle energy and is highly recommended for managing type 1-2 diabetes, as well as improving arterial elasticity.
Read More
9
Normalises blood pressure
2 people found this helpful
After suffering a stroke, my dad started taking taurine, which normalised his blood pressure, allowing him to stop chemical medications. His diabetes is also better managed since he incorporated taurine into his routine. It offers a multitude of benefits, but those with low blood pressure should use caution as it may lower it further.
Read More
7.5
Reduces blood glucose
2 people found this helpful
No allergic reactions were noted! Taurine, a natural product from sulfur-containing amino acids, exhibits osmoregulatory and membrane-protective properties. It positively affects the phospholipid structure of cell membranes and regulates calcium and potassium ion exchange. As an inhibitory neurotransmitter, it controls cortisol and other hormone responses, and improves metabolic processes in the heart and liver. In people with diabetes, taurine can significantly lower blood glucose levels, with notable improvements observed after two weeks of use.
Read More

Frequently Asked Questions

7.5
Improves cardiovascular health
3 people found this helpful
Taurine is an invaluable amino acid I've been advised to use by a specialist. Its effects become noticeable after around 1-2 months and it is particularly beneficial for elderly individuals and those on bed rest. It enhances muscle energy and is highly recommended for managing type 1-2 diabetes, as well as improving arterial elasticity.
7.5
Reduces blood glucose
2 people found this helpful
No allergic reactions were noted! Taurine, a natural product from sulfur-containing amino acids, exhibits osmoregulatory and membrane-protective properties. It positively affects the phospholipid structure of cell membranes and regulates calcium and potassium ion exchange. As an inhibitory neurotransmitter, it controls cortisol and other hormone responses, and improves metabolic processes in the heart and liver. In people with diabetes, taurine can significantly lower blood glucose levels, with notable improvements observed after two weeks of use.
7.5
Noticed sugar stability
87 people found this helpful
I tested taurine on my parents who suffer from high blood pressure and diabetes. After just a week of taking it, their sugar levels were noticeably more stable after eating, and their pressure began to decrease gradually. I would recommend it to others with similar issues.
9
Stabilised insulin levels
3 people found this helpful
Gorgeous drug. My mum drinks it for her diabetes, being overweight and having fatty liver. We are pleased with the results; the insulin levels in her blood have stabilised and both hepatosis and weight have decreased. The course of treatment lasts 3 to 6 months, taking two grams in the morning on an empty stomach.
8
Maintains stable sugar
1 people found this helpful
I began using taurine to combat constipation and was astonished by its effectiveness. I decided to give it to my grandfather who has diabetes, and it kept his blood sugar at lower rates with no changes in his diet or diabetes medication. Taurine clearly knows where to work.
9
Reduces blood sugar
2 people found this helpful
I purchased this for my mother, who has Type 2 diabetes, and these capsules effectively help to lower her blood sugar. Along with taurine, she takes other supplements for immunity. Best wishes for good health!
7.5
Essential for diabetes
2 people found this helpful
I ordered taurine for my father, who has Type 2 diabetes. It is essential for a diabetic diet since it helps lower sugar levels and improves eyesight. Although he hasn't been taking it long enough to see all benefits, I will update the review once we observe more improvements.
9
Normalises blood pressure
2 people found this helpful
After suffering a stroke, my dad started taking taurine, which normalised his blood pressure, allowing him to stop chemical medications. His diabetes is also better managed since he incorporated taurine into his routine. It offers a multitude of benefits, but those with low blood pressure should use caution as it may lower it further.
9
Supports bile fluidity
2 people found this helpful
My mother and I have been taking taurine for over a year, particularly for heart support and as adjunct therapy for her type 2 diabetes, helping to lower blood sugar. It also aids in bile fluidity, improving digestive health. Just be cautious, as taurine can lower blood pressure, which can be problematic for some.
7.5
Lowers blood glucose
174 people found this helpful
Taurine provides superb effects at a low price. It is a vital component of cardiovascular health. My family uses it as it enhances heart function, alleviates high blood pressure, and is beneficial in treating obesity and diabetes by reducing blood glucose levels and restoring insulin sensitivity.
8
Cornel iridoid glycosides effective for diabetes
We delved into the effects of cornel iridoid glycosides (CIG) on type 2 diabetes using a rat model. After inducing diabetes with a high-fat diet and streptozotocin, we examined various health indicators and conducted detailed metabolomic analyses of serum and urine.

Our findings suggested that CIG has significant antidiabetic effects, helping to control metabolic disorders in these diabetic rats. This research paves the way for clinical applications of CIG and enhances our understanding of its metabolic mechanisms.
8
Taurine may enhance diabetes outcomes
We explored the potential of taurine supplementation alongside metformin to enhance diabetes management and reduce complications. In our study, we used a group of sixty rats, half of which were diabetic and received different treatments. Some rats got metformin only, while others received metformin with taurine, cholecalciferol (Vitamin D), or both.

Observations revealed that diabetic rats had serious metabolic issues, including high glucose and fat levels, as well as low antioxidant enzyme activity. However, those treated with metformin combined with taurine and cholecalciferol showed significant improvements. Their metabolic parameters, including insulin levels and islet mass, responded positively to the combined supplements.

The findings suggest that the combination of taurine and metformin may help in controlling diabetes better by reducing inflammation and oxidative stress. This approach could lead to a more effective management strategy for patients struggling with diabetes-related complications.
8
Anthocyanins improve kidney function
We explored the impact of anthocyanins, specifically cyanidin-3-O-glucoside, on diabetic kidney disease (DKD). Through evaluating blood glucose and renal function, along with advanced metabolic analyses, we discovered that anthocyanins significantly reduced blood glucose levels and improved kidney function in treated mice compared to those not receiving treatment.

Our findings highlight that the benefits might stem from changes in amino acid metabolism. Incorporating dietary anthocyanins could be an effective strategy for preventing or managing DKD effectively.
We aimed to assess the benefits of a specialized fermented milk product on patients with type 2 diabetes who also experience abdominal obesity. Over 21 days, 40 patients were divided into two groups; one consumed the milk product while the other did not.

Good tolerability was noted, and both groups experienced significant weight loss and improvements in body composition. However, those who consumed the milk product showcased even greater benefits, such as increased vitamin levels and improved markers for fat and carbohydrate metabolism. Overall, this specialized product can be a helpful addition to diet therapy for those managing diabetes.
9
Taurine alleviates diabetes-induced liver injury
We conducted a study to explore the effects of taurine, an amino acid, on liver injury in rats with type 2 diabetes mellitus (T2DM). To simulate the condition, we fed the rats a high-fat diet and injected them with streptozotocin, which induced liver damage.

Our findings showed that administering taurine significantly reduced levels of liver enzymes, indicating better liver health. When we looked at liver cells under the microscope, they appeared much more normal, and we noticed fewer inflammatory cells in the liver.

Additionally, taurine boosted the liver's antioxidant defenses, increasing key indicators like SOD and CAT, which help combat oxidative stress. We also observed that taurine played a role in regulating inflammation, lowering the activity of certain inflammatory pathways linked to T2DM.

All of these results suggest that taurine can positively influence liver health by enhancing the liver's antioxidant capacity and reducing inflammation, offering hope for future diabetes treatments.
9
Taurine aids spinal cord recovery
We explored the impact of taurine on spinal cord axon injury, particularly in the context of diabetic neuropathy, a common complication arising from diabetes mellitus. Using a rat model induced by streptozotocin—essentially a tool to mimic diabetes—we found that taurine significantly reduced axonal damage observed in the spinal cord.

Our analysis included both morphological and functional assessments, revealing that taurine not only ameliorated damage but also promoted neurite outgrowth in neurons exposed to high glucose levels. This suggests that taurine could play a beneficial role in repairing neural injuries associated with diabetes.

We also noted that taurine boosts the expression of nerve growth factor (NGF) and GAP-43, essential proteins for nerve growth and repair. The observed improvements seem linked to the activation of specific signaling pathways, namely the NGF-pAkt-mTOR axis. Interestingly, blocking this pathway with certain inhibitors dampened the positive effects of taurine, highlighting its crucial role in the protection and repair of neural tissues in diabetic conditions.

Overall, our findings indicate that taurine could be a promising therapeutic agent for enhancing spinal cord recovery from diabetic-induced injuries, providing hope for better management of diabetic neuropathy.

References

  1. Hou Y, Huang Y, Shang Z, Ma S, Cui T, et al. Investigating the mechanism of cornel iridoid glycosides on type 2 diabetes mellitus using serum and urine metabolites in rats. J Ethnopharmacol. 2024;328:118065. 10.1016/j.jep.2024.118065
  2. Sharafetdinov KK, Novokshanova AL, Kochetkova AA, Plotnikova OA, Alekseeva RI, et al. [Assessment of the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders]. Vopr Pitan. 2024;93:67. 10.33029/0042-8833-2024-93-6-67-75
  3. Li YX, Lu YP, Tang D, Hu B, Zhang ZY, et al. Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism. J Transl Med. 2022;20:510. 10.1186/s12967-022-03717-9
  4. Tian J, Dang H, O'Laco KA, Song M, Tiu BC, et al. Homotaurine Treatment Enhances CD4 and CD8 Regulatory T Cell Responses and Synergizes with Low-Dose Anti-CD3 to Enhance Diabetes Remission in Type 1 Diabetic Mice. Immunohorizons. 2019;3:498. 10.4049/immunohorizons.1900019
  5. Zheng Y, Ceglarek U, Huang T, Wang T, Heianza Y, et al. Plasma Taurine, Diabetes Genetic Predisposition, and Changes of Insulin Sensitivity in Response to Weight-Loss Diets. J Clin Endocrinol Metab. 2016;101:3820.
  6. Abd El-Twab SM, Mohamed HM, Mahmoud AM. Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary-gonadal axis. Can J Physiol Pharmacol. 2016;94:651. 10.1139/cjpp-2015-0503
  7. Adrian TE, Gariballa S, Parekh KA, Thomas SA, Saadi H, et al. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia. 2012;55:2343. 10.1007/s00125-012-2593-2
  8. Song MK, Salam NK, Roufogalis BD, Huang TH. Lycium barbarum (Goji Berry) extracts and its taurine component inhibit PPAR-γ-dependent gene transcription in human retinal pigment epithelial cells: Possible implications for diabetic retinopathy treatment. Biochem Pharmacol. 2011;82:1209. 10.1016/j.bcp.2011.07.089
  9. Zeng K, Xu H, Chen K, Zhu J, Zhou Y, et al. Effects of taurine on glutamate uptake and degradation in Müller cells under diabetic conditions via antioxidant mechanism. Mol Cell Neurosci. 2010;45:192. 10.1016/j.mcn.2010.06.010
  10. Zeng K, Xu H, Mi M, Chen K, Zhu J, et al. Effects of taurine on glial cells apoptosis and taurine transporter expression in retina under diabetic conditions. Neurochem Res. 2010;35:1566. 10.1007/s11064-010-0216-1
  11. Gaamoussi F, Israili ZH, Lyoussi B. Hypoglycemic and hypolipidemic effects of an aqueous extract of Chamaerops humilis leaves in obese, hyperglycemic and hyperlipidemic Meriones shawi rats. Pak J Pharm Sci. 2010;23:212.
  12. Wang LJ, Yu YH, Zhang LG, Wang Y, Niu N, et al. Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: correlated with downregulation of LOX-1 and ICAM-1 expression on aortas. Eur J Pharmacol. 2008;597:75. 10.1016/j.ejphar.2008.08.031
  13. El-Akabawy G, Eid N. Enhancing metformin efficacy with cholecalciferol and taurine in diabetes therapy: Potential and limitations. World J Diabetes. 2025;16:100066. 10.4239/wjd.v16.i1.100066
  14. Tian S, Mei J, Zhang L, Wang S, Yuan Y, et al. Multifunctional Hydrogel Microneedle Patches Modulating Oxi-inflamm-aging for Diabetic Wound Healing. Small. 2024;20:e2407340. 10.1002/smll.202407340
  15. Attia MS, Ayman F, Attia MS, Yahya G, Zahra MH, et al. Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats. World J Diabetes. 2024;15:1778. 10.4239/wjd.v15.i8.1778
  16. Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity. Nature. 2024;633:182. 10.1038/s41586-024-07801-6
  17. Yuan J, Hou Q, He X, Zhong L, Li M, et al. Chitosan-taurine nanoparticles cross-linked carboxymethyl chitosan hydrogels facilitate both acute and chronic diabetic wound healing. Int J Biol Macromol. 2024;273:132762. 10.1016/j.ijbiomac.2024.132762
  18. Simões BES, Muniz MRR, Araujo TD, Magalhães Carneiro E, Simionato AVC. Evaluation of tauroursodeoxycholic acid in liver cells' cultures by MEKC: Initial hints to comprehend its role in diabetes mellitus of obese individuals. Electrophoresis. 2024;45:1252. 10.1002/elps.202300223
  19. Wang Y, Gao B, Chen X, Shi X, Li S, et al. Improvement of diabetes-induced spinal cord axon injury with taurine via nerve growth factor-dependent Akt/mTOR pathway. Amino Acids. 2024;56:32. 10.1007/s00726-024-03392-8
  20. Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. A PTER-dependent pathway of taurine metabolism linked to energy balance. bioRxiv. 2024. 10.1101/2024.03.21.586194
  21. Ouyang G, Wang N, Tong J, Sun W, Yang J, et al. Alleviation of taurine on liver injury of type 2 diabetic rats by improving antioxidant and anti-inflammatory capacity. Heliyon. 2024;10:e28400. 10.1016/j.heliyon.2024.e28400
image