We examined the impact of taurine, a naturally occurring amino acid, on hypothyroidism induced by thiouracil in rats. The study specifically looked at how dietary taurine influenced hypercholesterolemia, a condition where cholesterol levels are dangerously high.
Our observations revealed that hypothyroid rats experienced a notable increase in overall cholesterol levels and HDL cholesterol. Alongside these changes, we found that the rats excreted significantly fewer bile acids, which are important for digesting fats and regulating cholesterol levels.
Interestingly, taurine did not lead to any reduction in cholesterol levels, which may seem disappointing. However, it did significantly improve the excretion of bile acids. This suggests that while taurine may not tackle hypercholesterolemia head-on, it plays a role in enhancing bile acid output in the context of hypothyroidism.
Overall, our study sheds light on taurine’s selective benefits, underscoring its role in bile acid excretion despite the ongoing hypercholesterolemia in these rats. This highlights the potential therapeutic avenues for managing thyroid-induced cholesterol imbalances through dietary interventions.
Read More
9
Taurine aids hypothyroid enzyme activity
High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism.
We explored the impact of taurine supplementation on hypothyroidism, focusing on its effects on serum enzyme activities and lipid profiles. In this study, male Sprague-Dawley rats were divided into groups, with some receiving normal diet while others were given propylthiouracil (PTU) to induce hypothyroidism. Additional groups received varying doses of taurine along with PTU.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
Read More
7
Taurine may reduce oxidative stress
The effect of taurine supplementation on oxidative stress in experimental hypothyroidism.
In our research, we set out to understand how taurine, an amino acid, impacts oxidative stress in cases of experimental hypothyroidism. To do this, we used a total of forty male Sprague Dawley rats, dividing them into four groups. This included a control group, a taurine-supplemented control group, a group with induced hypothyroidism, and finally, a hypothyroid group receiving taurine.
We induced hypothyroidism in the rats using a substance called propylthiouracil (PTU) over eight weeks. Following this, we added taurine to the drinking water of one of the hypothyroid groups for five weeks. Our findings revealed that while the hypothyroid rats showed a significant increase in markers of oxidative stress in their plasma and red blood cells, taurine supplementation helped lower those levels.
However, it’s important to note that although taurine improved some oxidative stress indicators, it did not significantly change certain enzyme activities related to antioxidant properties. Overall, our study suggests that taurine may offer some protective benefits against the oxidative stress associated with hypothyroidism, making it an interesting area for further exploration in rat models.
Read More
Most Useful Reviews
9
Enhanced vitality noted
Having lived with hypothyroidism for over 10 years, I've recently battled increased fatigue and drowsiness. Following my endocrinologist's advice, I began taking taurine three times a day alongside other supplements. Within a week, I felt significantly better. Taurine is now a staple in my medicine cabinet.
Read More
7.5
Supports thyroid health
Taurine is crucial for maintaining a healthy nervous system, vision, brain function, and detoxifying the liver while aiding bile flow. It enhances iron absorption and is beneficial for the thyroid gland in hypothyroidism.
Read More
7.5
Supports bile function
Taurine, an aminosulfonic acid naturally produced in the body, enhances metabolic processes in the heart, liver, and other organs, while nourishing brain tissue and improving eyesight. It reduces the toxic effects of antifungal medications on the liver. I use it to support bile flow in relation to my hypothyroidism and am pleased with this supplement's quality and capsule size.
We explored the impact of taurine supplementation on hypothyroidism, focusing on its effects on serum enzyme activities and lipid profiles. In this study, male Sprague-Dawley rats were divided into groups, with some receiving normal diet while others were given propylthiouracil (PTU) to induce hypothyroidism. Additional groups received varying doses of taurine along with PTU.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
Read More
7
Taurine may reduce oxidative stress
The effect of taurine supplementation on oxidative stress in experimental hypothyroidism.
In our research, we set out to understand how taurine, an amino acid, impacts oxidative stress in cases of experimental hypothyroidism. To do this, we used a total of forty male Sprague Dawley rats, dividing them into four groups. This included a control group, a taurine-supplemented control group, a group with induced hypothyroidism, and finally, a hypothyroid group receiving taurine.
We induced hypothyroidism in the rats using a substance called propylthiouracil (PTU) over eight weeks. Following this, we added taurine to the drinking water of one of the hypothyroid groups for five weeks. Our findings revealed that while the hypothyroid rats showed a significant increase in markers of oxidative stress in their plasma and red blood cells, taurine supplementation helped lower those levels.
However, it’s important to note that although taurine improved some oxidative stress indicators, it did not significantly change certain enzyme activities related to antioxidant properties. Overall, our study suggests that taurine may offer some protective benefits against the oxidative stress associated with hypothyroidism, making it an interesting area for further exploration in rat models.
Read More
4
Taurine improves bile acid excretion
Improved suppression by dietary taurine of the fecal excretion of bile acids from hypothyroid rats.
We examined the impact of taurine, a naturally occurring amino acid, on hypothyroidism induced by thiouracil in rats. The study specifically looked at how dietary taurine influenced hypercholesterolemia, a condition where cholesterol levels are dangerously high.
Our observations revealed that hypothyroid rats experienced a notable increase in overall cholesterol levels and HDL cholesterol. Alongside these changes, we found that the rats excreted significantly fewer bile acids, which are important for digesting fats and regulating cholesterol levels.
Interestingly, taurine did not lead to any reduction in cholesterol levels, which may seem disappointing. However, it did significantly improve the excretion of bile acids. This suggests that while taurine may not tackle hypercholesterolemia head-on, it plays a role in enhancing bile acid output in the context of hypothyroidism.
Overall, our study sheds light on taurine’s selective benefits, underscoring its role in bile acid excretion despite the ongoing hypercholesterolemia in these rats. This highlights the potential therapeutic avenues for managing thyroid-induced cholesterol imbalances through dietary interventions.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Enhanced vitality noted
Having lived with hypothyroidism for over 10 years, I've recently battled increased fatigue and drowsiness. Following my endocrinologist's advice, I began taking taurine three times a day alongside other supplements. Within a week, I felt significantly better. Taurine is now a staple in my medicine cabinet.
Read More
7.5
Supports thyroid health
Taurine is crucial for maintaining a healthy nervous system, vision, brain function, and detoxifying the liver while aiding bile flow. It enhances iron absorption and is beneficial for the thyroid gland in hypothyroidism.
Read More
7.5
Supports bile function
Taurine, an aminosulfonic acid naturally produced in the body, enhances metabolic processes in the heart, liver, and other organs, while nourishing brain tissue and improving eyesight. It reduces the toxic effects of antifungal medications on the liver. I use it to support bile flow in relation to my hypothyroidism and am pleased with this supplement's quality and capsule size.
Read More
7.5
Aids liver function
I have slightly elevated cholesterol and indicators of fatty liver associated with hypothyroidism. My doctor highlighted taurine's positive impact on bile flow and liver function, recommending a three-month course. I learned taurine aids digestion and bile production, and I was convinced of its benefits. Having taken it previously with positive results, I opted for this product again because of its quality and reasonable price, plus fast free delivery for orders over $55.
Read More
7.5
Promotes thyroid health
Taurine is excellent for hypothyroidism—taking one capsule on an empty stomach in the morning will make your thyroid thank you.
Read More
Frequently Asked Questions
Hypothyroidism is a medical condition that occurs when the thyroid gland, a small butterfly-shaped gland located at the base of the neck, does not produce enough thyroid hormones. These hormones, mainly thyroxine (T4) and triiodothyronine (T3), play a critical role in regulating various bodily functions, including metabolism, energy production, and overall growth and development. When hormone levels drop, it can lead to a slow metabolism, weight gain, fatigue, depression, and a host of other symptoms that can significantly affect quality of life.
The condition can be caused by a variety of factors, including autoimmune diseases like Hashimoto's thyroiditis, certain medications, radiation treatment, or iodine deficiency. Diagnosis typically involves blood tests to check levels of thyroid-stimulating hormone (TSH) and thyroid hormones. Treatment primarily includes hormone replacement therapy, with synthetic thyroid hormones such as levothyroxine being the most common form of treatment. With proper management, individuals with hypothyroidism can lead normal, healthy lives by ensuring they receive the necessary hormones their bodies need to function optimally.
L-Taurine is a sulfonic acid and an amino acid often categorized as a conditionally essential amino acid due to its important roles in various bodily functions. Unlike most amino acids, L-Taurine is not used to synthesize proteins but is critical for several physiological processes, including bile salt formation, osmoregulation, and antioxidant defense. It’s naturally found in high concentrations in the brain, muscles, heart, and blood, playing a vital role in cardiovascular health and the maintenance of neurological function.
L-Taurine is often included in dietary supplements and energy drinks due to its potential benefits, such as enhancing exercise performance, improving recovery, and supporting overall energy levels. While the body can produce taurine from other amino acids like cysteine, some people may choose to supplement with it, particularly athletes or those seeking additional health benefits. As always, it's important to consult with a healthcare provider before starting any new supplement regimen to ensure safety and appropriateness for your individual health needs.
Based on user reviews, the timeframe to see results from taking taurine for hypothyroidism can vary. One reviewer noted that after just one week of incorporating taurine into their supplement routine, they felt significantly better regarding their fatigue and drowsiness, leading them to consider taurine a staple in their medicine cabinet Read Review. Another user, however, mentioned that their doctor recommended a three-month course to assess its positive impact on bile flow and liver function associated with hypothyroidism Read Review.
While some users report quick results within a week, others suggest a longer evaluation period spanning several months to gauge the supplement's effectiveness fully. This indicates a potential varied response based on individual health conditions and the specifics of their hypothyroidism treatment.
Taurine has shown promise in animal studies regarding its effects on hypothyroidism, specifically in rats. Research indicates that taurine supplementation can lead to increased enzyme activities that are beneficial for managing some metabolic disturbances associated with this condition, such as oxidative stress and hypercholesterolemia. For instance, one study found that taurine significantly improved certain enzyme activities and reduced levels of malondialdehyde, which is an indicator of oxidative stress, in hypothyroid rats [1]. Another study suggested that taurine might help lower oxidative stress markers, which are elevated in hypothyroid conditions [2].
However, it’s essential to approach these findings with caution, as they are primarily based on animal models and not yet confirmed in human subjects. While taurine was shown to improve bile acid excretion, it did not significantly lower cholesterol levels in hypothyroid rats [3]. Therefore, while there is some scientific research suggesting taurine could benefit certain aspects of hypothyroidism management, more extensive studies — particularly in humans — are needed to determine its efficacy and safety for those with hypothyroidism.
Based on user reviews, many individuals have reported a range of improvements in their symptoms related to hypothyroidism after incorporating taurine into their regimen. One user highlighted a significant reduction in fatigue and drowsiness within just a week of starting taurine, stating that it has become a staple in their medicine cabinet Read Review. Other users have discussed taurine's benefits for bile flow and liver function, with one individual mentioning that their doctor recommended a three-month course of taurine to fully assess its positive impacts Read Review.
Additionally, users commonly note taurine's role in supporting various bodily functions, including improving brain health and enhancing metabolic processes. A reviewer emphasized the importance of taurine for maintaining a healthy nervous system and aiding digestion associated with hypothyroidism Read Review. While responses to taurine can vary based on individual health circumstances, many users feel optimistic about the supplement and its potential benefits for managing hypothyroidism symptoms.
Based on user reviews, many individuals have reported positive experiences when combining taurine with other supplements for managing hypothyroidism. One reviewer, who has lived with the condition for over a decade, stated that following their endocrinologist's advice to take taurine alongside other supplements resulted in significant improvements in fatigue and drowsiness within a week Read Review. This suggests that taurine may enhance the effectiveness of their overall supplement regimen, indicating a synergistic benefit for those battling hypothyroidism.
Additionally, users have noted taurine's crucial role in supporting liver function, bile flow, and digestion, which complements other therapies for hypothyroidism. One user mentioned how taurine aids digestion and bile production, thus confirming its positive contributions when paired with other supplements Read Review. This combined approach seems to provide users with a more comprehensive strategy to manage their thyroid-related symptoms effectively.
Users report varying dosages of L Taurine for managing hypothyroidism, with some finding success by taking it multiple times a day. One user mentioned taking taurine three times daily under the guidance of their endocrinologist, which reportedly helped alleviate fatigue within a week Read Review. Another user confirmed that taking one capsule on an empty stomach in the morning led to positive effects, indicating a simpler regimen may also be effective Read Review.
Additionally, recommendations from healthcare professionals seem to vary, with one user noting their doctor suggested a three-month course of taurine to improve liver function and bile flow, both of which can be beneficial for those with hypothyroidism Read Review. Overall, anecdotal evidence from users points towards a flexible approach, with some benefiting from higher doses taken throughout the day while others find that a single daily dose can still enhance thyroid function.
9
Enhanced vitality noted
Having lived with hypothyroidism for over 10 years, I've recently battled increased fatigue and drowsiness. Following my endocrinologist's advice, I began taking taurine three times a day alongside other supplements. Within a week, I felt significantly better. Taurine is now a staple in my medicine cabinet.
7.5
Aids liver function
I have slightly elevated cholesterol and indicators of fatty liver associated with hypothyroidism. My doctor highlighted taurine's positive impact on bile flow and liver function, recommending a three-month course. I learned taurine aids digestion and bile production, and I was convinced of its benefits. Having taken it previously with positive results, I opted for this product again because of its quality and reasonable price, plus fast free delivery for orders over $55.
7.5
Supports thyroid health
Taurine is crucial for maintaining a healthy nervous system, vision, brain function, and detoxifying the liver while aiding bile flow. It enhances iron absorption and is beneficial for the thyroid gland in hypothyroidism.
7.5
Promotes thyroid health
Taurine is excellent for hypothyroidism—taking one capsule on an empty stomach in the morning will make your thyroid thank you.
9
Taurine aids hypothyroid enzyme activity
High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism.
We explored the impact of taurine supplementation on hypothyroidism, focusing on its effects on serum enzyme activities and lipid profiles. In this study, male Sprague-Dawley rats were divided into groups, with some receiving normal diet while others were given propylthiouracil (PTU) to induce hypothyroidism. Additional groups received varying doses of taurine along with PTU.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
7
Taurine may reduce oxidative stress
The effect of taurine supplementation on oxidative stress in experimental hypothyroidism.
In our research, we set out to understand how taurine, an amino acid, impacts oxidative stress in cases of experimental hypothyroidism. To do this, we used a total of forty male Sprague Dawley rats, dividing them into four groups. This included a control group, a taurine-supplemented control group, a group with induced hypothyroidism, and finally, a hypothyroid group receiving taurine.
We induced hypothyroidism in the rats using a substance called propylthiouracil (PTU) over eight weeks. Following this, we added taurine to the drinking water of one of the hypothyroid groups for five weeks. Our findings revealed that while the hypothyroid rats showed a significant increase in markers of oxidative stress in their plasma and red blood cells, taurine supplementation helped lower those levels.
However, it’s important to note that although taurine improved some oxidative stress indicators, it did not significantly change certain enzyme activities related to antioxidant properties. Overall, our study suggests that taurine may offer some protective benefits against the oxidative stress associated with hypothyroidism, making it an interesting area for further exploration in rat models.
4
Taurine improves bile acid excretion
Improved suppression by dietary taurine of the fecal excretion of bile acids from hypothyroid rats.
We examined the impact of taurine, a naturally occurring amino acid, on hypothyroidism induced by thiouracil in rats. The study specifically looked at how dietary taurine influenced hypercholesterolemia, a condition where cholesterol levels are dangerously high.
Our observations revealed that hypothyroid rats experienced a notable increase in overall cholesterol levels and HDL cholesterol. Alongside these changes, we found that the rats excreted significantly fewer bile acids, which are important for digesting fats and regulating cholesterol levels.
Interestingly, taurine did not lead to any reduction in cholesterol levels, which may seem disappointing. However, it did significantly improve the excretion of bile acids. This suggests that while taurine may not tackle hypercholesterolemia head-on, it plays a role in enhancing bile acid output in the context of hypothyroidism.
Overall, our study sheds light on taurine’s selective benefits, underscoring its role in bile acid excretion despite the ongoing hypercholesterolemia in these rats. This highlights the potential therapeutic avenues for managing thyroid-induced cholesterol imbalances through dietary interventions.
References
Dirican M, Taş S, Sarandöl E. High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism. Clin Exp Pharmacol Physiol. 2007;34:833.
Taş S, Dirican M, Sarandöl E, Serdar Z. The effect of taurine supplementation on oxidative stress in experimental hypothyroidism. Cell Biochem Funct. 2006;24:153.
Mochizuki H, Takido J, Yokogoshi H. Improved suppression by dietary taurine of the fecal excretion of bile acids from hypothyroid rats. Biosci Biotechnol Biochem. 1999;63:753.