We examined a case of a 40-year-old woman who struggled for a decade with vague symptoms like fatigue and numbness, initially diagnosed with various other conditions. It wasn't until further investigation that she was found to have critically low vitamin B12 levels due to pernicious anemia.

After starting parenteral B12 therapy, we saw significant neurologic improvement, highlighting the vital role vitamin B12 plays in treating neuropathy. This case serves as a reminder to consider vitamin deficiencies in similar patients, even when traditional blood tests don't reveal anemia.

Burning pain relief

Most Useful Review

56 people found this helpful

After 15 years of burning pain in my legs post-gastric bypass surgery, I found this product after learning about a B vitamin deficiency's role in neuropathy. It has provided relief greater than any opioids or pain medication I've tried; this has truly been a lifesaver for me.

Updated: Mar 2026

We looked into how Vitamin B2 supplementation might help with migraines, focusing on its potential to reduce the number of migraine days, duration, frequency, and pain scores.

Using systematic reviews and meta-analyses, we explored data from multiple reliable databases. Our findings reveal that taking 400 mg of Vitamin B2 daily for three months can significantly cut down on migraine days, duration, frequency, and pain levels.

So, if you're seeking alternatives to pharmaceuticals, Vitamin B2 could be a beneficial option to consider.

Boosts energy and mood

Most Useful Review

46 people found this helpful

This is my favourite vitamin. It alleviates migraines, boosts energy, and ensures a good night's sleep. I've been taking B1 for nearly a year, helping to relieve fatigue and weakness from stress. I take it regularly, even instead of coffee, to combat migraines, especially after stressful days.

Updated: Mar 2026

Premenstrual Syndrome details

8 people found this helpful

Thiamine perfectly calms nerves, especially during PMS. I take it alongside standard vitamins and cease when the tension subsides—this has been my routine each month.

Updated: Apr 2025

Adrenal Gland Disorder details

2 people found this helpful

I require vitamin B1 to support my adrenal glands, along with pantothenic acid, and it works!

Updated: Mar 2026

Allergies details

No allergies experienced

Most Useful Review

Excellent quality! The ingredients are perfectly chosen, and I experienced no allergies or negative reactions. The large package lasts a long time, and I saw improvements in my intestinal function and nervous system after just a week of use.

Updated: Mar 2026

Celiac details

I truly needed this! My trigger finger improved remarkably fast after hearing a British nutritionist discuss B1's benefits for the condition, which I was experiencing. It worked astonishingly quickly. I suspect my deficiency is due to avoiding bread. This is a fantastic supplement for anyone gluten-free, as it helps prevent your hands from curling up and becoming unusable!

Updated: Apr 2025

Depression details

7 people found this helpful

This vitamin is fantastic for alleviating depression! I use it alongside other supplements to help with anxiety and panic.

Updated: Mar 2026

Heart Disease details

Normalised hand function

Most Useful Review

22 people found this helpful

I ordered vitamin B1 for my mother, who has heart disease accompanied by symptoms like numbness in her hands. After a month of taking it, the numbness has disappeared, and she feels much better. I’m pleased with the results and the product's quality.

Updated: Mar 2026

Indigestion details

5 people found this helpful

I recently began taking Vitamin B1 supplements for their benefits on digestion and energy production, and I'm delighted with the results. The supplement is straightforward to take and has noticeably boosted my digestion and energy levels. I feel more energised throughout the day, even after consuming a large meal. My digestion has improved significantly; I no longer experience bloating or indigestion. Additionally, Vitamin B1 aids in metabolism. Overall, I wholeheartedly recommend this supplement!

Updated: Apr 2025

Rash details

Rash improvement noted

Most Useful Review

25 people found this helpful

B1 or thiamine is a vitamin that needs to be consumed daily with food, which can be challenging. During my treatment for psoriasis, I was prescribed a course of injections containing thiamine. I decided to give these vitamins a try. The results have been notable, particularly on my hands, where the rashes have started to fade after six years of battling this condition. I also used a cream for better effect. Additionally, I ordered Omega3 supplements from a website, as I wondered if there might be a beneficial interaction. I hope my feedback is helpful to someone.

Updated: Apr 2025

Back Pain details

I experienced pain in the bottom of my feet, which has almost disappeared, likely due to a B1 deficiency. The quality is good, and I highly recommend it.

Updated: Apr 2025

Blurred Vision details

1 people found this helpful

My eyes used to experience jagged flashes and blurred vision. Despite consultations with an ophthalmologist and cardiologist, the cause was unclear. Since using this product, those issues have not recurred. This has been the most effective experience I've had with various vitamins.

Updated: Apr 2025

Bone Pain details

Nerve pain management

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2 people found this helpful

This vitamin is remarkable for alleviating tingling, numbness, and limb pain.

Updated: Apr 2025

Cardiovascular Disease details

3 people found this helpful

Vitamin B1 is crucial for cardiovascular and nervous systems, aiding in glucose and fat metabolism while mitigating harmful effects of glucose and insulin on blood vessels.

Updated: Mar 2026

Chest Pain details

Stiff shoulders relief

Most Useful Review

10 people found this helpful

It effectively alleviates stiff shoulders and muscle pain associated with remote work. After prolonged working hours during the pandemic, I suffered from stiffness. Taking one tablet of Now B1 before bed left me feeling refreshed by morning. This supplement is superior to over-the-counter alternatives and has no unnecessary ingredients. I train in martial arts thrice a week, and after using it, my usual hamstring discomfort lessens, allowing me to enjoy playing in the park with my children.

Updated: Mar 2025

Chronic Cough details

9 people found this helpful

I am delighted Vitamin B1 has saved me from chronic fatigue. After months of taking glycine, GABA, and magnesium B6 with no major changes, I felt reborn from the first day of B1. The results exceeded my expectations; my nervous system functioned like when I was in school. I experienced a rush of blood to my brain and energy throughout my body. I no longer need coffee! The quality of the vitamin is excellent, with compact packaging, standard-sized tablets, and neutral taste. As someone who is insulin resistant, B1 has proven to be pivotal for my wellness. I heartily recommend it!

Updated: Apr 2025

Constipation details

Effective for constipation.

Most Useful Review

1 people found this helpful

The best aspect of this B1 product is its natural form, requiring no enzymes for absorption. It’s advisable to take it on alternating days, ensuring quality and good ingredients. It effectively helps reduce constipation and boosts metabolism without any taste.

Updated: Mar 2026

Insomnia details

25 people found this helpful

Recently, I struggled with anxiety and insomnia. After trying Valerian without success, I took B1 alongside B6 and magnesium before bed. I found it easier to sleep, and my energy levels improved significantly within a few days. The capsules are a decent size and well-priced for the quality.

Updated: Mar 2026

Parkinson details

2 people found this helpful

B1 is part of five different enzymes, serving as a cofactor, and its deficiency causes fatigue. Factors such as diabetes, excessive alcohol, and consumption of large carbohydrates lead to B1 deficiency. This vitamin protects cells from oxidation and compounds that can harm the brain. A lack of B1 may cause heart enlargement, rapid pulse, and leg swelling. It also affects the nervous system, leading to tingling, digestive issues, dizziness, anxiety, and insomnia. The deficit stems from sugar, excess calories, refined foods, and certain health conditions. I take Vitamin B1 with Nutritional Yeast before exercising, which has significantly boosted my strength and improved my memory. For those with Alzheimer's or Parkinson's, it's essential. If you relate to these symptoms, I encourage you to try this dietary supplement!

Updated: Mar 2026

Diabetes details

Pain management success

Most Useful Review

54 people found this helpful

After 15 years with diabetes and no prescription medications, I find particular supplements, including biotin and niacinamide, helpful for nerve repair and pain management. Topical creams also play a crucial role.

Updated: Mar 2026

High Cholesterol details

Energy levels enhanced

Most Useful Review

2 people found this helpful

Vitamin B-1 has been impactful in supporting my energy production and ensuring a healthy nervous system. Since incorporating this supplement into my routine, I've seen a significant lift in my energy levels and focus, without any jitters. The quality of the product is excellent, making it a noteworthy addition to my wellness regimen.

Updated: Mar 2026

Menopause details

11 people found this helpful

Headaches no longer trouble me. Since entering menopause, I experienced nearly constant headaches and frequent migraines. However, since taking this alongside Magnesium Glycinate and B2, my headaches are nearly a thing of the past. I've regained my life! Thank you, iHerb!

Updated: Apr 2025

Mild Cognitive Impairment details

Memory improvement noted

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4 people found this helpful

The doctor advised taking B1 for elders with dementia. After just one week, I noticed an improvement in memory and overall condition. I would highly recommend it for alleviating dementia symptoms.

Updated: Apr 2025

Swollen Lymph Nodes details

Less morning swelling

Most Useful Review

I experience morning swelling, which hasn’t completely resolved, but it has significantly decreased. Poor blood circulation used to cause frequent disruptions in my sleep, but since starting these supplements, I find I’m waking up much less often.

Updated: Mar 2026

Ulcer details

I've used this product for years, and it represents excellent value. A bottle lasts a long time, aids my sleep, and accelerates the healing of mouth ulcers. I can't be without it.

Updated: Apr 2026

Attention Deficit Hyperactivity Disorder details

Significant ADHD improvement

Most Useful Review

9 people found this helpful

Since I started taking B1, my life has transformed! I feel calmer and more energetic, even noticing that I’ve stopped biting my nails. When I had to stop taking it, I missed the energy and felt anxious again. I give it to my 9-year-old son with attention deficit hyperactivity disorder; it's remarkable how much his hyperactivity has improved since he began taking it. I’ll never stop using it.

Updated: Mar 2026

Autoimmune Disorder details

Mixed results observed

Most Useful Review

I periodically take B vitamins due to a folate cycle disorder. This brand is economical, but I’m uncertain about its efficacy as I didn’t achieve the results I was hoping for. I’ll continue to monitor its effects on my condition.

Updated: Mar 2026

Hypothyroidism details

SCIENTIFIC SCORE

Moderately Effective

Based on 6 Researches

B vitamins reduce homocysteine in hypothyroid rats

Nechyporuk V, Korda M, Pentiuk L, Dmytrenko I, Bulko I. The impact of B vitamins on the functioning of methylation cycle in the liver and the kidneys of hyper- and hypothyroid rats. Pol Merkur Lekarski. 2020;48:55.

This experimental study investigated whether B vitamins could correct metabolic problems associated with thyroid dysfunction. Researchers induced hypothyroidism and hyperthyroidism in rats over 21 days, then examined how these conditions affected the methylation cycle—a key metabolic pathway dependent on vitamins B9, B12, and related compounds.

Hypothyroidism disrupted this cycle, reducing enzyme activity and raising homocysteine levels—a risk factor for heart disease. When the researchers treated hypothyroid rats with folic acid, vitamin B12, and pyridoxine, these B vitamins significantly lowered homocysteine levels, suggesting they may help prevent cardiovascular complications in people with hypothyroidism. Though conducted in animals, the findings indicate B vitamins warrant further investigation as a potential supportive treatment.

Eliminated fatigue

Most Useful Review

3 people found this helpful

My digestive issues have vanished, and my pancreas is functioning well. I no longer experience drowsiness or constant fatigue. All signs of hypothyroidism have disappeared. I will definitely continue with this supplement.