' 
![]()
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 12 Reviews
8.7
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Thiamin(from Thiamin HCl) (Vitamin B-1)
100 mg
8,333%
Top Medical Research Studies
9
Thiamin improves memory in hypothyroidism
Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase.
Directly addresses thiamin's efficacy
Our study focused on how thiamin, also known as Vitamin B1, can help with learning and memory issues caused by hypothyroidism. We designed an experiment using 50 rats, which we treated with propylthiouracil to induce hypothyroidism and then supplemented with varying doses of thiamin. Over a period of seven weeks, we assessed the rats’ abilities to remember and learn through standard tests like the Morris water maze and passive avoidance tasks.
We observed that thiamin significantly improved the ability of hypothyroid rats to recall the location of a hidden platform in the water maze. The rats that received higher doses of thiamin spent less time finding the platform and traveled shorter distances compared to those in the hypothyroid group who did not receive the supplement. Similarly, in the passive avoidance test, rats treated with thiamin demonstrated longer delays before entering a dark chamber, indicating improved memory retention.
Additionally, thiamin showed promise in reducing oxidative stress and decreasing acetylcholinesterase activity in the brain. This suggests that thiamin may help to rebalance certain chemicals in the brain, contributing to better memory function. Overall, our findings support the potential benefits of thiamin for addressing learning and memory deficits in cases of hypothyroidism, primarily by improving oxidative status and cholinergic function.
We observed that thiamin significantly improved the ability of hypothyroid rats to recall the location of a hidden platform in the water maze. The rats that received higher doses of thiamin spent less time finding the platform and traveled shorter distances compared to those in the hypothyroid group who did not receive the supplement. Similarly, in the passive avoidance test, rats treated with thiamin demonstrated longer delays before entering a dark chamber, indicating improved memory retention.
Additionally, thiamin showed promise in reducing oxidative stress and decreasing acetylcholinesterase activity in the brain. This suggests that thiamin may help to rebalance certain chemicals in the brain, contributing to better memory function. Overall, our findings support the potential benefits of thiamin for addressing learning and memory deficits in cases of hypothyroidism, primarily by improving oxidative status and cholinergic function.
Read More
8
Thiamine reduces fatigue in patients
Thiamine and Hashimoto's thyroiditis: a report of three cases.
Moderate relevance to hypothyroidism
We explored the effects of thiamine on fatigue experienced by individuals with Hashimoto's thyroiditis, a common autoimmune condition linked to hypothyroidism. Our investigation involved three patients who were already receiving thyroid hormone replacement therapy. They reported ongoing fatigue despite having normal thyroid function tests.
We decided to address this fatigue with high doses of thiamine, offering either oral or parenteral administration. We measured fatigue levels using the Fatigue Severity Scale and checked thiamine levels in the serum and red cells before and after treatment.
After administering thiamine, we observed that all three patients experienced a partial or complete reduction in fatigue. This subtle improvement suggests that thiamine may play a role in alleviating fatigue, potentially indicating a mild thiamine deficiency related to the autoimmune process of Hashimoto's thyroiditis. However, since the patients were on thyroid hormones, we cannot fully isolate thiamine's effects.
We decided to address this fatigue with high doses of thiamine, offering either oral or parenteral administration. We measured fatigue levels using the Fatigue Severity Scale and checked thiamine levels in the serum and red cells before and after treatment.
After administering thiamine, we observed that all three patients experienced a partial or complete reduction in fatigue. This subtle improvement suggests that thiamine may play a role in alleviating fatigue, potentially indicating a mild thiamine deficiency related to the autoimmune process of Hashimoto's thyroiditis. However, since the patients were on thyroid hormones, we cannot fully isolate thiamine's effects.
Read More
Most Useful Reviews
9.5
Eliminated fatigue
My digestive issues have vanished, and my pancreas is functioning well. I no longer experience drowsiness or constant fatigue. All signs of hypothyroidism have disappeared. I will definitely continue with this supplement.
Read More
9.5
Boosted energy
This supplement gives me a significant boost of energy and positively impacts my daily life. If I forget to take it, fatigue returns, making functioning difficult. I highly recommend it for those with thyroid issues.
Read More
7.5
Energy Improvement
Good B vitamins are essential for everyone, especially with age. I take vitamin B1 regularly due to my hypothyroidism, as it is crucial for converting food into energy, which I struggle with. This NOW product offers great value and quality, and I recommend it to anyone facing energy and motivation issues.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
9
Thiamin improves memory in hypothyroidism
Ameliorative effects of thiamin on learning behavior and memory dysfunction in a rat model of hypothyroidism: implication of oxidative stress and acetylcholinesterase.
Directly addresses thiamin's efficacy
Our study focused on how thiamin, also known as Vitamin B1, can help with learning and memory issues caused by hypothyroidism. We designed an experiment using 50 rats, which we treated with propylthiouracil to induce hypothyroidism and then supplemented with varying doses of thiamin. Over a period of seven weeks, we assessed the rats’ abilities to remember and learn through standard tests like the Morris water maze and passive avoidance tasks.
We observed that thiamin significantly improved the ability of hypothyroid rats to recall the location of a hidden platform in the water maze. The rats that received higher doses of thiamin spent less time finding the platform and traveled shorter distances compared to those in the hypothyroid group who did not receive the supplement. Similarly, in the passive avoidance test, rats treated with thiamin demonstrated longer delays before entering a dark chamber, indicating improved memory retention.
Additionally, thiamin showed promise in reducing oxidative stress and decreasing acetylcholinesterase activity in the brain. This suggests that thiamin may help to rebalance certain chemicals in the brain, contributing to better memory function. Overall, our findings support the potential benefits of thiamin for addressing learning and memory deficits in cases of hypothyroidism, primarily by improving oxidative status and cholinergic function.
We observed that thiamin significantly improved the ability of hypothyroid rats to recall the location of a hidden platform in the water maze. The rats that received higher doses of thiamin spent less time finding the platform and traveled shorter distances compared to those in the hypothyroid group who did not receive the supplement. Similarly, in the passive avoidance test, rats treated with thiamin demonstrated longer delays before entering a dark chamber, indicating improved memory retention.
Additionally, thiamin showed promise in reducing oxidative stress and decreasing acetylcholinesterase activity in the brain. This suggests that thiamin may help to rebalance certain chemicals in the brain, contributing to better memory function. Overall, our findings support the potential benefits of thiamin for addressing learning and memory deficits in cases of hypothyroidism, primarily by improving oxidative status and cholinergic function.
Read More
8
Thiamine reduces fatigue in patients
Thiamine and Hashimoto's thyroiditis: a report of three cases.
Moderate relevance to hypothyroidism
We explored the effects of thiamine on fatigue experienced by individuals with Hashimoto's thyroiditis, a common autoimmune condition linked to hypothyroidism. Our investigation involved three patients who were already receiving thyroid hormone replacement therapy. They reported ongoing fatigue despite having normal thyroid function tests.
We decided to address this fatigue with high doses of thiamine, offering either oral or parenteral administration. We measured fatigue levels using the Fatigue Severity Scale and checked thiamine levels in the serum and red cells before and after treatment.
After administering thiamine, we observed that all three patients experienced a partial or complete reduction in fatigue. This subtle improvement suggests that thiamine may play a role in alleviating fatigue, potentially indicating a mild thiamine deficiency related to the autoimmune process of Hashimoto's thyroiditis. However, since the patients were on thyroid hormones, we cannot fully isolate thiamine's effects.
We decided to address this fatigue with high doses of thiamine, offering either oral or parenteral administration. We measured fatigue levels using the Fatigue Severity Scale and checked thiamine levels in the serum and red cells before and after treatment.
After administering thiamine, we observed that all three patients experienced a partial or complete reduction in fatigue. This subtle improvement suggests that thiamine may play a role in alleviating fatigue, potentially indicating a mild thiamine deficiency related to the autoimmune process of Hashimoto's thyroiditis. However, since the patients were on thyroid hormones, we cannot fully isolate thiamine's effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.7
9.5
Eliminated fatigue
My digestive issues have vanished, and my pancreas is functioning well. I no longer experience drowsiness or constant fatigue. All signs of hypothyroidism have disappeared. I will definitely continue with this supplement.
9.5
Boosted energy
This supplement gives me a significant boost of energy and positively impacts my daily life. If I forget to take it, fatigue returns, making functioning difficult. I highly recommend it for those with thyroid issues.
9
Must for thyroid
B1 is essential for those like me suffering from hypothyroidism. The tablets are small and easy to swallow. I will certainly purchase again due to the good quality.
8.8
Improved tiredness
I have Hashimoto's, which leads to hypothyroidism and low stomach acid. Taking B1 has helped with the formation of stomach acid. I feel less tired since I started taking B1 daily.
8.8
Essential B vitamin
Thiamine, or B1, converts carbohydrates into energy and aids digestion, particularly for those with hypothyroidism. I take 1 tablet daily to maintain optimal levels, as recommended for women over 20.
