Last update
5/25/2025
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 9 Reviews
8.1
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Vitamin C (as Ascorbic Acid)
500 mg
556%
Rose Hips Powder (Rosa canina) (fruit)
40 mg

Top Medical Research Studies

8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

Most Useful Reviews

9
No heartburn noted
4 people found this helpful
Good; it does not cause heartburn!
Read More
10
Satisfied with results
This is my second purchase. It contains rose hips and vitamins, which I find satisfactory. The pill size is just right, and I experienced no heartburn, even when taken on an empty stomach.
Read More
9
No side effects reported
A good vitamin I use on a low-carb diet. With limited food intake, I needed vitamin C that wouldn’t irritate my stomach or cause heartburn. After taking it for over a month, I have experienced no side effects for my gastrointestinal tract. I highly recommend it for those with a sensitive stomach.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
No heartburn noted
4 people found this helpful
Good; it does not cause heartburn!
Read More
10
Satisfied with results
This is my second purchase. It contains rose hips and vitamins, which I find satisfactory. The pill size is just right, and I experienced no heartburn, even when taken on an empty stomach.
Read More
9
No side effects reported
A good vitamin I use on a low-carb diet. With limited food intake, I needed vitamin C that wouldn’t irritate my stomach or cause heartburn. After taking it for over a month, I have experienced no side effects for my gastrointestinal tract. I highly recommend it for those with a sensitive stomach.
Read More
9
No heartburn experienced
Excellent! I took it with iron for better absorption; it did not cause heartburn and had no negative effects.
Read More
9
Easy to take
Great brand, easy to take, with no heartburn.
Read More

Frequently Asked Questions

9
No side effects reported
A good vitamin I use on a low-carb diet. With limited food intake, I needed vitamin C that wouldn’t irritate my stomach or cause heartburn. After taking it for over a month, I have experienced no side effects for my gastrointestinal tract. I highly recommend it for those with a sensitive stomach.
9
No heartburn noted
4 people found this helpful
Good; it does not cause heartburn!
2
Avoid if sensitive
The manufacturer is good, but since I consume Vitamin C throughout the day, this one feels too sour for me! I hope the ingredients are sound, but I haven't noticed any significant changes. If you take the full dose, it may work well! However, I struggled with terrible heartburn after it got stuck in my esophagus, so I recommend drinking plenty of water.
9
No heartburn issues
I've had no issues with this vitamin C supplement. Sometimes, these supplements give me heartburn; however, I haven't experienced that yet.
9
No heartburn experienced
Excellent! I took it with iron for better absorption; it did not cause heartburn and had no negative effects.
10
Satisfied with results
This is my second purchase. It contains rose hips and vitamins, which I find satisfactory. The pill size is just right, and I experienced no heartburn, even when taken on an empty stomach.
9
No heartburn experienced
Normal. I appreciate it; there is no heartburn, although I do not suffer from heartburn with Vit S. My entire family took large doses during a cold and thankfully did not fall ill.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.

Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.

Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.

References

  1. Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
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