We explored the effects of ascorbic acid and its derivatives on the replication of Herpes simplex virus type I using human muscle cancer cells.
The study revealed that a specific form of vitamin C, known as 2-O-glycoside of ascorbic acid, showed promising antiviral properties.
Interestingly, while this derivative can inhibit certain chemical reactions involving carbon-centered radicals, it does not impact reactions with oxygen-centered radicals.
However, despite these findings, the overall benefits of vitamin C treatment for herpes remain inconclusive.
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9
Vitamin C shows potential in herpes treatment
Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution.
We investigated the effectiveness of a topical solution containing ascorbic acid for treating recurrent herpes outbreaks. Our double-blind, placebo-controlled clinical trial involved a rigorous application method and comprehensive symptom tracking by both patients and nurses.
Results showed that those treated with the ascorbic acid formulation experienced fewer days with scabs and reported less symptom severity compared to the placebo group. Additionally, virus cultures indicated a lower presence of the herpes simplex virus in the treatment group.
Overall, this brief treatment demonstrated promising antiviral effects, warranting further research.
Read More
8
Vitamin C shows limited activity against herpes
In vitro effect of ascorbic acid on infectivity of herpesviruses and paramyxoviruses.
We looked into how vitamin C, specifically when combined with copper, affects the herpes simplex virus. Our findings showed that suspensions of herpes viruses could be inactivated within just 24 hours using a specific concentration of copper-catalyzed sodium ascorbate.
However, while the effective inactivation was interesting, we noticed that higher doses didn’t significantly improve the outcome. This suggests that while vitamin C has a role, it might not be a game-changer when it comes to treating herpes infections.
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Most Useful Reviews
9
Effective for herpes
3 people found this helpful
Bomb against viruses really helps. I constantly suffer from Herpes. As soon as I feel it starting on my lip, I take it, and it removes everything as if by magic. I would definitely recommend.
Read More
9
Quick relief
Bomb against viruses really works. I suffer from Herpes consistently. When it begins to pound on my lip, I take it and it sorts everything out effortlessly. I would certainly recommend it.
Read More
9
Consistent effectiveness
This really helps. I suffer from Herpes consistently. When it begins on my lip, I take it, and it resolves everything as if by magic. I would definitely advise taking it.
We explored how copper, combined with ascorbic acid (vitamin C), can effectively inactivate the herpes simplex virus (HSV). Using a specific concentration of copper and vitamin C, we noticed that virus plaque formation was reduced by over 99.9%, all while keeping host cells 30% alive.
The study highlighted that ascorbate played a crucial role in this inactivation process compared to other agents like hydrogen peroxide. This points towards the potential of copper and vitamin C in developing new treatments for managing herpes infections.
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9
Vitamin C may reduce shingles symptoms
Intravenous vitamin C in the treatment of shingles: results of a multicenter prospective cohort study.
We explored the potential benefits of intravenous vitamin C for patients suffering from shingles, also known as herpes zoster. In this multicenter study, 67 participants received vitamin C alongside standard treatment for two weeks.
Over a 12-week follow-up, we noted significant reductions in pain and dermatologic symptoms. Participants reported less fatigue and improved concentration, suggesting that vitamin C might help alleviate common complaints associated with shingles.
However, more rigorous placebo-controlled studies are needed to confirm these findings.
Read More
9
Limited antiviral benefits observed
Radical-regulating and antiviral properties of ascorbic acid and its derivatives.
We explored the effects of ascorbic acid and its derivatives on the replication of Herpes simplex virus type I using human muscle cancer cells.
The study revealed that a specific form of vitamin C, known as 2-O-glycoside of ascorbic acid, showed promising antiviral properties.
Interestingly, while this derivative can inhibit certain chemical reactions involving carbon-centered radicals, it does not impact reactions with oxygen-centered radicals.
However, despite these findings, the overall benefits of vitamin C treatment for herpes remain inconclusive.
Read More
9
Vitamin C shows potential for herpes relief
Intravenous administration of vitamin C in the treatment of herpetic neuralgia: two case reports.
We observed two cases of acute herpetic neuralgia (AHN) where vitamin C was administered intravenously in conjunction with standard pain relief. During a two-week period, both patients showed a remarkable and complete reduction of neuropathic pain and improvement in skin lesions following vitamin C treatment.
While these results are promising, they emphasize the need for larger randomized trials to solidify vitamin C's role in treating herpes-related nerve pain. Overall, vitamin C may serve as a useful complement to existing therapies for specific cases of herpes zoster complications.
Read More
9
Vitamin C shows potential in herpes treatment
Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution.
We investigated the effectiveness of a topical solution containing ascorbic acid for treating recurrent herpes outbreaks. Our double-blind, placebo-controlled clinical trial involved a rigorous application method and comprehensive symptom tracking by both patients and nurses.
Results showed that those treated with the ascorbic acid formulation experienced fewer days with scabs and reported less symptom severity compared to the placebo group. Additionally, virus cultures indicated a lower presence of the herpes simplex virus in the treatment group.
Overall, this brief treatment demonstrated promising antiviral effects, warranting further research.
Bomb against viruses really helps. I constantly suffer from Herpes. As soon as I feel it starting on my lip, I take it, and it removes everything as if by magic. I would definitely recommend.
Read More
9
Quick relief
Bomb against viruses really works. I suffer from Herpes consistently. When it begins to pound on my lip, I take it and it sorts everything out effortlessly. I would certainly recommend it.
Read More
9
Consistent effectiveness
This really helps. I suffer from Herpes consistently. When it begins on my lip, I take it, and it resolves everything as if by magic. I would definitely advise taking it.
Read More
9
Effective transition
I did not notice any effect when I took vitamin C in California, as my Herpes did not flare up. However, with these vitamins, I saw an immediate result. When I moved to California, my Herpes cleared up within three days.
Read More
8
Accelerates healing
This is a brilliant solution, especially for those who are prone to Herpes. This vitamin significantly speeds up healing from within. I have tested it for myself!
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
Auezova R, Adirakhan A, Mussabekova K, Aldiyarova N, Akshulakov S, et al. Treatment of Herpes Zoster-Associated Neurological Complications with High-Dose Intravenous Ascorbic Acid: Two Case Reports. Int Med Case Rep J. 2025;18:421. 10.2147/IMCRJ.S514241
Liu Y, Wang M, Xiong MM, Zhang XG, Fang M. Intravenous Administration of Vitamin C in the Treatment of Herpes Zoster-Associated Pain: Two Case Reports and Literature Review. Pain Res Manag. 2020;2020:8857287. 10.1155/2020/8857287
Kim GN, Yoo WS, Park MH, Chung JK, Han YS, et al. Clinical Features of Herpes Simplex Keratitis in a Korean Tertiary Referral Center: Efficacy of Oral Antiviral and Ascorbic Acid on Recurrence. Korean J Ophthalmol. 2018;32:353. 10.3341/kjo.2017.0131
Kim MS, Kim DJ, Na CH, Shin BS. A Study of Intravenous Administration of Vitamin C in the Treatment of Acute Herpetic Pain and Postherpetic Neuralgia. Ann Dermatol. 2016;28:677. PubMed
Schencking M, Vollbracht C, Weiss G, Lebert J, Biller A, et al. Intravenous vitamin C in the treatment of shingles: results of a multicenter prospective cohort study. Med Sci Monit. 2012;18:CR215. PubMed
Brinkevich SD, Boreko EI, Savinova OV, Pavlova NI, Shadyro OI. Radical-regulating and antiviral properties of ascorbic acid and its derivatives. Bioorg Med Chem Lett. 2012;22:2424. 10.1016/j.bmcl.2012.02.022
Byun SH, Jeon Y. Administration of Vitamin C in a Patient with Herpes Zoster - A case report -. Korean J Pain. 2011;24:108. 10.3344/kjp.2011.24.2.108
Schencking M, Sandholzer H, Frese T. Intravenous administration of vitamin C in the treatment of herpetic neuralgia: two case reports. Med Sci Monit. 2010;16:CS58. PubMed
Lopez BS, Yamamoto M, Utsumi K, Aratsu C, Sakagami H. A clinical pilot study of lignin--ascorbic acid combination treatment of herpes simplex virus. In Vivo. 2009;23:1011. PubMed
Furuya A, Uozaki M, Yamasaki H, Arakawa T, Arita M, et al. Antiviral effects of ascorbic and dehydroascorbic acids in vitro. Int J Mol Med. 2008;22:541. PubMed
Betanzos-Cabrera G, Ramírez FJ, Muñoz JL, Barrón BL, Maldonado R. Inactivation of HSV-2 by ascorbate-Cu(II) and its protecting evaluation in CF-1 mice against encephalitis. J Virol Methods. 2004;120:161. PubMed
Hamuy R, Berman B. Topical antiviral agents for herpes simplex virus infections. Drugs Today (Barc). 1998;34:1013. PubMed
Hovi T, Hirvimies A, Stenvik M, Vuola E, Pippuri R. Topical treatment of recurrent mucocutaneous herpes with ascorbic acid-containing solution. Antiviral Res. 1995;27:263. PubMed
White LA, Freeman CY, Forrester BD, Chappell WA. In vitro effect of ascorbic acid on infectivity of herpesviruses and paramyxoviruses. J Clin Microbiol. 1986;24:527. PubMed
Cathcart RF. Vitamin C in the treatment of acquired immune deficiency syndrome (AIDS). Med Hypotheses. 1984;14:423. PubMed