' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 11 Researches
8.1
USERS' SCORE
Very Good
Based on 7 Reviews
8.7
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
9.5
Vitamin D3 aids chronic hives
Resolution of chronic urticaria coincident with vitamin D supplementation.
High relevance to chronic urticaria
We explored the potential benefits of vitamin D3 supplementation specifically for individuals experiencing chronic hives. This study focused on the direct impact of vitamin D3, allowing us to isolate its effects from other treatments.
Over the course of the study, we observed significant improvements in symptoms among participants who received vitamin D3. Many reported a noticeable reduction in hives, suggesting that vitamin D3 may help alleviate this bothersome condition.
The findings point towards vitamin D3 as an effective treatment option for managing chronic urticaria. This could offer new hope for those who have struggled with persistent hives, emphasizing the importance of considering vitamin D levels in treatment strategies.
Over the course of the study, we observed significant improvements in symptoms among participants who received vitamin D3. Many reported a noticeable reduction in hives, suggesting that vitamin D3 may help alleviate this bothersome condition.
The findings point towards vitamin D3 as an effective treatment option for managing chronic urticaria. This could offer new hope for those who have struggled with persistent hives, emphasizing the importance of considering vitamin D levels in treatment strategies.
Read More
9
Vitamin D3 improves chronic hives
The effect of vitamin D add-on therapy on the improvement of quality of life and clinical symptoms of patients with chronic spontaneous urticaria.
Directly addresses vitamin D3 effectiveness.
We aimed to discover how vitamin D3 supplementation affects chronic spontaneous urticaria, commonly known as hives. In a well-structured study, 80 participants were randomly assigned to receive either low (4200 IU/week) or high (28,000 IU/week) doses of vitamin D3 over 12 weeks.
Our findings were encouraging. Both groups showed a significant reduction in the severity of their hives, but those taking the higher dose experienced even greater improvements. After just six weeks, the high-dose group reported notably lower severity scores compared to the low-dose group. By weeks six and twelve, quality of life ratings also significantly improved, particularly for those receiving the higher dosage.
We observed that levels of 25-hydroxyvitamin D, an important marker for vitamin D in the body, rose significantly in both groups, with the high-dose group showing a much greater increase. Although the reduction in medication use was significant for all, we didn’t find any notable differences between the groups in this regard. Interestingly, we did not see any strong links between positive skin test results or specific antibody levels related to thyroid function and a positive response to vitamin D treatment.
Overall, adding vitamin D3 at a higher dosage appears to be a safe and potentially effective approach for managing symptoms associated with chronic hives.
Our findings were encouraging. Both groups showed a significant reduction in the severity of their hives, but those taking the higher dose experienced even greater improvements. After just six weeks, the high-dose group reported notably lower severity scores compared to the low-dose group. By weeks six and twelve, quality of life ratings also significantly improved, particularly for those receiving the higher dosage.
We observed that levels of 25-hydroxyvitamin D, an important marker for vitamin D in the body, rose significantly in both groups, with the high-dose group showing a much greater increase. Although the reduction in medication use was significant for all, we didn’t find any notable differences between the groups in this regard. Interestingly, we did not see any strong links between positive skin test results or specific antibody levels related to thyroid function and a positive response to vitamin D treatment.
Overall, adding vitamin D3 at a higher dosage appears to be a safe and potentially effective approach for managing symptoms associated with chronic hives.
Read More
9
Vitamin D3 aids chronic urticaria
Does replacement of vitamin D reduce the symptom scores and improve quality of life in patients with chronic urticaria?
Study shows vitamin D3 effectiveness
We explored the potential benefits of vitamin D3 supplementation for people suffering from chronic urticaria, commonly known as hives. In this study, we included 58 patients diagnosed with chronic spontaneous urticaria (CSU) and compared them with 45 control subjects.
The participants' vitamin D levels were measured, revealing that many CSU patients had lower levels than normal. For those with vitamin D levels below 30 µg/L, we administered a significant dose of 300,000 IU of vitamin D3 each month alongside their standard treatment.
After three months, we evaluated the impact of this supplementation through specific measures of urticaria severity and quality of life. Our findings indicate that vitamin D3 may play a beneficial role in improving both the frequency and intensity of hives symptoms, as well as enhancing the overall quality of life for these patients.
Overall, our results support the idea that replacing vitamin D can lead to meaningful improvements for those dealing with chronic urticaria.
The participants' vitamin D levels were measured, revealing that many CSU patients had lower levels than normal. For those with vitamin D levels below 30 µg/L, we administered a significant dose of 300,000 IU of vitamin D3 each month alongside their standard treatment.
After three months, we evaluated the impact of this supplementation through specific measures of urticaria severity and quality of life. Our findings indicate that vitamin D3 may play a beneficial role in improving both the frequency and intensity of hives symptoms, as well as enhancing the overall quality of life for these patients.
Overall, our results support the idea that replacing vitamin D can lead to meaningful improvements for those dealing with chronic urticaria.
Read More
Most Useful Reviews
9.5
Atopy elimination
After switching from niacinamide to this vitamin D3 for my child’s atopic dermatitis, the hives and skin irritation disappeared within weeks. The eczema on joints has completely resolved! I am astounded at this transformation after years of suffering.
Read More
9.5
Hives and pressure
I discovered that I had a significant vitamin D deficiency. After taking this vitamin D for over six months, I am no longer troubled by hives or fluctuations in blood pressure. I prefer this brand over others.
Read More
8.3
Chronic hives cure
Since starting this vitamin, I have been cured of chronic hives that plagued me last winter. I am now a firm believer in the benefits of vitamin D.
Read More
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Medical Researches
SCIENTIFIC SCORE
Most Likely Effective
Based on 11 Researches
8.1
9.5
Vitamin D3 aids chronic hives
Resolution of chronic urticaria coincident with vitamin D supplementation.
High relevance to chronic urticaria
We explored the potential benefits of vitamin D3 supplementation specifically for individuals experiencing chronic hives. This study focused on the direct impact of vitamin D3, allowing us to isolate its effects from other treatments.
Over the course of the study, we observed significant improvements in symptoms among participants who received vitamin D3. Many reported a noticeable reduction in hives, suggesting that vitamin D3 may help alleviate this bothersome condition.
The findings point towards vitamin D3 as an effective treatment option for managing chronic urticaria. This could offer new hope for those who have struggled with persistent hives, emphasizing the importance of considering vitamin D levels in treatment strategies.
Over the course of the study, we observed significant improvements in symptoms among participants who received vitamin D3. Many reported a noticeable reduction in hives, suggesting that vitamin D3 may help alleviate this bothersome condition.
The findings point towards vitamin D3 as an effective treatment option for managing chronic urticaria. This could offer new hope for those who have struggled with persistent hives, emphasizing the importance of considering vitamin D levels in treatment strategies.
Read More
9
Vitamin D3 improves chronic hives
The effect of vitamin D add-on therapy on the improvement of quality of life and clinical symptoms of patients with chronic spontaneous urticaria.
Directly addresses vitamin D3 effectiveness.
We aimed to discover how vitamin D3 supplementation affects chronic spontaneous urticaria, commonly known as hives. In a well-structured study, 80 participants were randomly assigned to receive either low (4200 IU/week) or high (28,000 IU/week) doses of vitamin D3 over 12 weeks.
Our findings were encouraging. Both groups showed a significant reduction in the severity of their hives, but those taking the higher dose experienced even greater improvements. After just six weeks, the high-dose group reported notably lower severity scores compared to the low-dose group. By weeks six and twelve, quality of life ratings also significantly improved, particularly for those receiving the higher dosage.
We observed that levels of 25-hydroxyvitamin D, an important marker for vitamin D in the body, rose significantly in both groups, with the high-dose group showing a much greater increase. Although the reduction in medication use was significant for all, we didn’t find any notable differences between the groups in this regard. Interestingly, we did not see any strong links between positive skin test results or specific antibody levels related to thyroid function and a positive response to vitamin D treatment.
Overall, adding vitamin D3 at a higher dosage appears to be a safe and potentially effective approach for managing symptoms associated with chronic hives.
Our findings were encouraging. Both groups showed a significant reduction in the severity of their hives, but those taking the higher dose experienced even greater improvements. After just six weeks, the high-dose group reported notably lower severity scores compared to the low-dose group. By weeks six and twelve, quality of life ratings also significantly improved, particularly for those receiving the higher dosage.
We observed that levels of 25-hydroxyvitamin D, an important marker for vitamin D in the body, rose significantly in both groups, with the high-dose group showing a much greater increase. Although the reduction in medication use was significant for all, we didn’t find any notable differences between the groups in this regard. Interestingly, we did not see any strong links between positive skin test results or specific antibody levels related to thyroid function and a positive response to vitamin D treatment.
Overall, adding vitamin D3 at a higher dosage appears to be a safe and potentially effective approach for managing symptoms associated with chronic hives.
Read More
9
Vitamin D3 aids chronic urticaria
Does replacement of vitamin D reduce the symptom scores and improve quality of life in patients with chronic urticaria?
Study shows vitamin D3 effectiveness
We explored the potential benefits of vitamin D3 supplementation for people suffering from chronic urticaria, commonly known as hives. In this study, we included 58 patients diagnosed with chronic spontaneous urticaria (CSU) and compared them with 45 control subjects.
The participants' vitamin D levels were measured, revealing that many CSU patients had lower levels than normal. For those with vitamin D levels below 30 µg/L, we administered a significant dose of 300,000 IU of vitamin D3 each month alongside their standard treatment.
After three months, we evaluated the impact of this supplementation through specific measures of urticaria severity and quality of life. Our findings indicate that vitamin D3 may play a beneficial role in improving both the frequency and intensity of hives symptoms, as well as enhancing the overall quality of life for these patients.
Overall, our results support the idea that replacing vitamin D can lead to meaningful improvements for those dealing with chronic urticaria.
The participants' vitamin D levels were measured, revealing that many CSU patients had lower levels than normal. For those with vitamin D levels below 30 µg/L, we administered a significant dose of 300,000 IU of vitamin D3 each month alongside their standard treatment.
After three months, we evaluated the impact of this supplementation through specific measures of urticaria severity and quality of life. Our findings indicate that vitamin D3 may play a beneficial role in improving both the frequency and intensity of hives symptoms, as well as enhancing the overall quality of life for these patients.
Overall, our results support the idea that replacing vitamin D can lead to meaningful improvements for those dealing with chronic urticaria.
Read More
9
Vitamin D3 improves hives treatment
Chronic urticaria merits serum vitamin D evaluation and supplementation; a randomized case control study.
Combines Vitamin D with standard care.
We examined how Vitamin D3 might impact Chronic Urticaria (hives) symptoms in a study involving 192 participants. The subjects were categorized based on their initial Vitamin D levels and divided into three groups. One group received only Vitamin D3, another group was treated with antihistamines and corticosteroids, and the third group received a combination of both VitD3 and the other medications.
Over a period of six weeks, we measured the changes in urticarial symptoms using a visual analogue scale and a 5-D itch score. Our findings revealed that a significant number of Chronic Urticaria patients had low Vitamin D levels at the outset. After treatment, participants who received both Vitamin D3 and the standard medications showed the most improvement in their symptoms.
However, the data indicates that Vitamin D3 alone may not be a standalone solution for hives. Instead, its best effect seems to emerge when used alongside traditional treatments. This research emphasizes the importance of checking Vitamin D levels in individuals with Chronic Urticaria before starting any treatment.
Over a period of six weeks, we measured the changes in urticarial symptoms using a visual analogue scale and a 5-D itch score. Our findings revealed that a significant number of Chronic Urticaria patients had low Vitamin D levels at the outset. After treatment, participants who received both Vitamin D3 and the standard medications showed the most improvement in their symptoms.
However, the data indicates that Vitamin D3 alone may not be a standalone solution for hives. Instead, its best effect seems to emerge when used alongside traditional treatments. This research emphasizes the importance of checking Vitamin D levels in individuals with Chronic Urticaria before starting any treatment.
Read More
8
Vitamin D therapy benefits hives
Vitamin D suppress the production of vascular endothelial growth factor in mast cell by inhibiting PI3K/Akt/p38 MAPK/HIF-1α pathway in chronic spontaneous urticaria.
Study shows vitamin D insights
We explored how vitamin D impacts chronic spontaneous urticaria (CSU), a condition commonly known as hives. In a detailed analysis, we looked at the proteins found in the blood serum of patients with CSU compared to healthy individuals. Our findings identified a significant increase in vitamin D binding protein (VDBP) among those with CSU, suggesting a connection between vitamin D levels and this skin condition.
Our research revealed that serum from CSU patients triggered mast cells to produce vascular endothelial growth factor (VEGF), a key player in inflammation and allergic reactions. This production was mediated through specific signaling pathways, namely the PI3K/Akt/p38 MAPK/HIF-1α axis, which relies on Immunoglobulin E (IgE). Importantly, we observed that treatment with 25(OH)D, a form of vitamin D, effectively suppressed the expression of VEGF by inhibiting these signaling pathways.
These results indicate that vitamin D could play a beneficial role in managing CSU by altering the inflammatory responses in mast cells. Overall, our study suggests that VDBP may serve as a potential biomarker for CSU and supports the idea that vitamin D therapy could benefit patients suffering from this condition.
Our research revealed that serum from CSU patients triggered mast cells to produce vascular endothelial growth factor (VEGF), a key player in inflammation and allergic reactions. This production was mediated through specific signaling pathways, namely the PI3K/Akt/p38 MAPK/HIF-1α axis, which relies on Immunoglobulin E (IgE). Importantly, we observed that treatment with 25(OH)D, a form of vitamin D, effectively suppressed the expression of VEGF by inhibiting these signaling pathways.
These results indicate that vitamin D could play a beneficial role in managing CSU by altering the inflammatory responses in mast cells. Overall, our study suggests that VDBP may serve as a potential biomarker for CSU and supports the idea that vitamin D therapy could benefit patients suffering from this condition.
Read More
User Reviews
USERS' SCORE
Very Good
Based on 7 Reviews
8.7
9.5
Atopy elimination
After switching from niacinamide to this vitamin D3 for my child’s atopic dermatitis, the hives and skin irritation disappeared within weeks. The eczema on joints has completely resolved! I am astounded at this transformation after years of suffering.
9.5
Hives and pressure
I discovered that I had a significant vitamin D deficiency. After taking this vitamin D for over six months, I am no longer troubled by hives or fluctuations in blood pressure. I prefer this brand over others.
8.8
Hives disappearance
Very good! Since staying at home more due to Covid, I developed terrible hives from the waist down. Despite taking medicine from a dermatologist for six months, it was ineffective. However, after learning about the benefits of sunlight and vitamin D, my hives vanished the next day! It appears my issue was due to a vitamin D deficiency.
Read More
8.8
Hives relief
The dosage is very good for the endless grey days. It quickly raises vitamin D levels, enhancing mood and helping stave off hives.
8.3
Chronic hives cure
Since starting this vitamin, I have been cured of chronic hives that plagued me last winter. I am now a firm believer in the benefits of vitamin D.
