'
SCIENTIFIC SCORE
Most Likely Effective
Based on 9 Researches
7.6
USERS' SCORE
Very Good
Based on 15 Reviews
8.2
Supplement Facts
Serving Size:   1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%

Top Medical Research Studies

8
Vitamin D reduces triglycerides effectively
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
Directly relevant to obesity management
We explored the effects of vitamin D supplementation on lipid profiles in overweight and obese women. Our investigation included data from various randomized controlled trials (RCTs) that specifically examined how vitamin D might influence cholesterol and triglyceride levels in this population.

Our analysis revealed that vitamin D had a significant impact on lowering triglycerides and total cholesterol levels. We found reductions of about 6.13 mg/dL for triglycerides and 4.45 mg/dL for total cholesterol. Additionally, there was a noteworthy increase in HDL cholesterol, the “good” cholesterol, by an average of 1.54 mg/dL.

Interestingly, we noticed that those with higher baseline triglyceride levels saw even greater benefits, particularly with a significant reduction in triglycerides when vitamin D was supplemented for 26 weeks or less. However, it’s important to mention that vitamin D supplementation did not have a significant effect on LDL cholesterol levels in this group.

Overall, our findings suggest that vitamin D can be an effective option for managing certain aspects of lipid profiles in overweight or obese women, particularly in addressing high triglycerides.
Read More
8
Vitamin D3 supports obesity management
Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity.
Crucial insights on pediatric obesity
We conducted a study to explore the relationship between vitamin D3 and obesity, particularly focusing on its impact on cholesterol levels, glucose metabolism, and bone health in children. Our research involved 723 pediatric participants, with some receiving vitamin D3 supplements and others a placebo over a two-year period.

The results showed promising findings. Those in the vitamin D3 group experienced a meaningful reduction in cholesterol levels, triglycerides, and fasting glucose. We also observed significant improvements in bone density. The data indicated that higher levels of vitamin D3 were linked to better metabolic health, providing a clear connection between vitamin D3 supplementation and managing obesity-related complications.

Overall, our research suggests that supplementing with vitamin D3 could be a beneficial strategy for enhancing metabolic health in children facing obesity. It’s an exciting advancement for clinicians aiming to support healthy growth and development in pediatric patients.
Read More
5
Vitamin D3 affects triglycerides only
The effect of vitamin D on the lipid profile in individuals with overweight or obesity: A meta-analysis and systematic review of randomized controlled trials.
High relevance to obesity studies
We set out to investigate how vitamin D3 could influence the lipid profiles of people dealing with obesity or overweight issues. By examining various randomized controlled trials, we aimed to clarify the connection between vitamin D supplementation and changes in cholesterol and triglyceride levels.

Our findings indicated that vitamin D did produce notable changes in triglyceride levels, particularly in those with obesity. For instance, when we looked into specific groups—like those with existing health conditions or higher baseline triglyceride levels—we observed significant reductions in triglycerides. However, it’s crucial to note that vitamin D supplementation did not yield any significant effects on LDL cholesterol, HDL cholesterol, or total cholesterol levels.

Overall, while we found some positive impacts of vitamin D on triglyceride levels, it does not seem to affect all aspects of lipid profiles in overweight individuals. This suggests that while vitamin D has its benefits, it may not be a comprehensive solution for obesity-related lipid issues.
Read More

Most Useful Reviews

8.8
Improves obesity issues
Vitamin D3 deficiency is prevalent and affects many people. It can arise from various factors such as poor sunlight exposure and genetic issues. When taking vitamin D, start with small doses if you have anaemia. It’s advisable for seniors with gastrointestinal issues to use sublingual forms for better absorption. For breastfeeding mothers, ensure optimal levels before dosing infants. Those with obesity may need nearly double the recommended dose, and adequate levels of magnesium and vitamin A are vital.
Read More
8
Supports obesity treatment
Vitamin D plays a critical role in absorbing calcium and phosphorus, essential for various bodily functions. Chronic deficiency in children is linked to a higher risk of diabetes, obesity, and other diseases. Regular vitamin D supplementation can alleviate symptoms of irritable bowel syndrome. The capsules are small, easy to swallow with no aftertaste, and bolster immunity, support thyroid function, and help regulate blood pressure and heart health.
Read More
8.8
Necessary for obesity
Vitamin D's role extends beyond strong bones; deficiency can lead to obesity, infertility, diabetes, and more. The optimal blood concentration is considered to be between 30-100 ng/ml, with higher levels being beneficial. The therapeutic dosage should be determined by a healthcare professional based on testing results.
Read More

Medical Researches

SCIENTIFIC SCORE
Most Likely Effective
Based on 9 Researches
7.6
8
Vitamin D reduces triglycerides effectively
Effect of Vitamin D Supplementation on Lipid Profile in Overweight or Obese Women: A Meta-analysis and Systematic Review of Randomized Controlled Trials.
Directly relevant to obesity management
We explored the effects of vitamin D supplementation on lipid profiles in overweight and obese women. Our investigation included data from various randomized controlled trials (RCTs) that specifically examined how vitamin D might influence cholesterol and triglyceride levels in this population.

Our analysis revealed that vitamin D had a significant impact on lowering triglycerides and total cholesterol levels. We found reductions of about 6.13 mg/dL for triglycerides and 4.45 mg/dL for total cholesterol. Additionally, there was a noteworthy increase in HDL cholesterol, the “good” cholesterol, by an average of 1.54 mg/dL.

Interestingly, we noticed that those with higher baseline triglyceride levels saw even greater benefits, particularly with a significant reduction in triglycerides when vitamin D was supplemented for 26 weeks or less. However, it’s important to mention that vitamin D supplementation did not have a significant effect on LDL cholesterol levels in this group.

Overall, our findings suggest that vitamin D can be an effective option for managing certain aspects of lipid profiles in overweight or obese women, particularly in addressing high triglycerides.
Read More
8
Vitamin D3 supports obesity management
Vitamin D Supplementation Reduces Hyperlipidemia and Improves Bone Mass in Pediatric Obesity.
Crucial insights on pediatric obesity
We conducted a study to explore the relationship between vitamin D3 and obesity, particularly focusing on its impact on cholesterol levels, glucose metabolism, and bone health in children. Our research involved 723 pediatric participants, with some receiving vitamin D3 supplements and others a placebo over a two-year period.

The results showed promising findings. Those in the vitamin D3 group experienced a meaningful reduction in cholesterol levels, triglycerides, and fasting glucose. We also observed significant improvements in bone density. The data indicated that higher levels of vitamin D3 were linked to better metabolic health, providing a clear connection between vitamin D3 supplementation and managing obesity-related complications.

Overall, our research suggests that supplementing with vitamin D3 could be a beneficial strategy for enhancing metabolic health in children facing obesity. It’s an exciting advancement for clinicians aiming to support healthy growth and development in pediatric patients.
Read More
8
Vitamin D3 aids post-surgery recovery
Effects of native vitamin D supplementation on vitamin D status and body composition after sleeve gastrectomy: A retrospective study in Japanese patients.
Relevant but indirectly addresses obesity
We analyzed how vitamin D3 supplementation could influence vitamin D levels and body composition in patients who had undergone sleeve gastrectomy, a common type of weight loss surgery. In our study, we looked at data from 83 Japanese patients, with half receiving guidance on vitamin D3 supplementation during their recovery. The group that took vitamin D3 showed a significant increase in their vitamin D levels after three months, suggesting a positive effect on their nutritional status.

Interestingly, we found that this boost in vitamin D levels correlated with the preservation of lower limb muscle mass after surgery. Those who took the supplement also reported engaging in more exercise, which seemed to further support their recovery. While the study didn’t directly show that vitamin D3 treatments reduce obesity, the improvements in vitamin D levels and muscle mass suggest it could play a role in overall health and recovery post-surgery.

In conclusion, ensuring adequate vitamin D levels post-surgery, potentially through supplementation, may help prevent loss of muscle mass, which is crucial for maintaining overall fitness and health during weight loss. This research provides new insights into the nutritional needs of bariatric patients and highlights the importance of incorporating vitamin D management in their care plans.
Read More
8
Vitamin D3 mitigates BPA-induced obesity
1,25‑Dihydroxyvitamin D3 mitigates the adipogenesis induced by bisphenol A in 3T3-L1 and hAMSC through miR-27-3p regulation.
Strong relevance to obesity mechanisms.
In exploring the relationship between vitamin D3 and obesity, we investigated how 1,25-Dihydroxyvitamin D3 (VitD) influences fat cell growth. Our focus was on two types of cells: mouse pre-adipocytes (3T3-L1) and human adipose-derived mesenchymal stem cells (hAMSC).

We aimed to determine if VitD could help prevent adipogenesis, a process promoted by the chemical bisphenol A (BPA), known for disrupting endocrine function and impacting metabolic rates. Through various tests, we treated our cell models with different concentrations of VitD and BPA throughout the maturation into fat cells.

The results were promising. We found that VitD not only showed an anti-adipogenic effect on its own but also significantly countered the fat-storing effects of BPA. This protective influence of VitD appeared to involve the regulation of certain miRNAs, specifically miR-27-3p, which play a role in fat cell differentiation and function.

Overall, our findings suggest that incorporating vitamin D3 may be beneficial in managing obesity, especially in environments with BPA exposure.
Read More
8
Vitamin D3 and obesity correlation
Association of serum 25-hydroxy vitamin D status with cardiometabolic risk factors and total and regional obesity in southern Iran: evidence from the PoCOsteo study.
Study shows significant associations
We set out to understand how vitamin D3 might influence obesity and related health issues in older adults. Through data gathered from 1,991 participants in the PoCOsteo study, we looked at levels of 25-hydroxy vitamin D3, alongside a range of blood sugar and cholesterol levels, as well as measurements of both total and regional fat using DXA scans.

Surprisingly, we found that nearly 39% of the participants were vitamin D deficient. After accounting for other factors that might impact health, our analysis revealed a clear trend: higher levels of vitamin D were associated with lower body mass index, reduced waist circumference, and decreased regional fat. This suggests that maintaining adequate vitamin D levels may help manage obesity.

Furthermore, we observed that higher vitamin D levels corresponded with healthier blood pressure, cholesterol, triglycerides, and blood sugar levels. Notably, for every increase in vitamin D concentration, the risk of dyslipidemia decreased by about 2%. Overall, our findings highlight that vitamin D levels are significantly linked to various obesity metrics and other cardiometabolic risk factors, making it an essential area for further exploration.
Read More

User Reviews

USERS' SCORE
Very Good
Based on 15 Reviews
8.2
9.5
Supports weight management
I am very pleased with Vitamin D3. It plays a crucial role in regulating over 5,000 genes. Its deficiency can lead to conditions like obesity and various health issues. This product contains a high concentration of vitamin D-3 and is made from quality ingredients.
9.5
Boosts overall health
I find this vitamin D to be an effective product. The 5,000 IU dosage suits my needs perfectly. While taking it, I was ill only once, which I attribute to my use of vitamin D, especially while working in a hospital environment during colds and Covid-19.
9
Reduces obesity risk
Long-term vitamin D intake is crucial for several health benefits including immune regulation, heart disease reduction, and obesity management. Vitamin D helps minimise asthma symptoms and supports the skeletal system, crucial for women in managing obesity-related issues. Thank you!
9
Supports obesity control
Vitamin D3 is vital for various body functions, including immune and nervous system regulation and reducing obesity risk. It helps combat diseases like multiple sclerosis and supports healthy weight maintenance. Regular intake is essential for overall health.
8.8
Improves obesity issues
Vitamin D3 deficiency is prevalent and affects many people. It can arise from various factors such as poor sunlight exposure and genetic issues. When taking vitamin D, start with small doses if you have anaemia. It’s advisable for seniors with gastrointestinal issues to use sublingual forms for better absorption. For breastfeeding mothers, ensure optimal levels before dosing infants. Those with obesity may need nearly double the recommended dose, and adequate levels of magnesium and vitamin A are vital.
Read More
image