Overview
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
5.3
USERS' SCORE
Good
Based on 4 Reviews
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
4
We designed a fascinating case-control study to investigate how vitamin D might influence the risk of developing rosacea, a common skin condition. In our research, we compared patients who have rosacea to healthy individuals, assessing their vitamin D levels and specific variations in their vitamin D receptor genes.
The findings indicated that patients with rosacea had notably higher levels of serum 25-hydroxyvitamin D. In fact, those with elevated vitamin D levels had a 1.36-fold increased risk of developing rosacea. We also discovered that certain genetic variations, such as the ApaI and TaqI polymorphisms, played a significant role in rosacea susceptibility, with heterozygous and mutant forms of the ApaI variants particularly increasing risk.
These results suggest that vitamin D and its receptor pathways may be contributing factors in rosacea development. However, it’s important to note that while these associations are compelling, causality remains unclear, meaning we cannot conclude that vitamin D treatment will definitively affect rosacea outcomes.
The findings indicated that patients with rosacea had notably higher levels of serum 25-hydroxyvitamin D. In fact, those with elevated vitamin D levels had a 1.36-fold increased risk of developing rosacea. We also discovered that certain genetic variations, such as the ApaI and TaqI polymorphisms, played a significant role in rosacea susceptibility, with heterozygous and mutant forms of the ApaI variants particularly increasing risk.
These results suggest that vitamin D and its receptor pathways may be contributing factors in rosacea development. However, it’s important to note that while these associations are compelling, causality remains unclear, meaning we cannot conclude that vitamin D treatment will definitively affect rosacea outcomes.
Read More
4
We explored the connection between vitamin D levels and rosacea by comparing serum vitamin D in patients with this skin condition to healthy individuals. Our study included 44 rosacea patients and 32 controls, with the aim of understanding whether vitamin D plays a role in the development of rosacea.
Interestingly, we found that the average vitamin D levels were higher in the rosacea patients (21.4 ng/ml) compared to the control group (17.1 ng/ml), a difference that was statistically significant. However, when looking at vitamin D deficiency, the prevalence was quite similar between the two groups—38.6% of rosacea patients were deficient compared to 28.1% of healthy controls.
These findings suggest that patients with rosacea may have higher vitamin D levels, and it raises the question of whether elevated vitamin D could be contributing to the condition. Nevertheless, more extensive studies are necessary to clarify the role of vitamin D in rosacea, as our research was the first of its kind to investigate this relationship. We acknowledge the need for further investigation to confirm these results and understand the implications better.
Interestingly, we found that the average vitamin D levels were higher in the rosacea patients (21.4 ng/ml) compared to the control group (17.1 ng/ml), a difference that was statistically significant. However, when looking at vitamin D deficiency, the prevalence was quite similar between the two groups—38.6% of rosacea patients were deficient compared to 28.1% of healthy controls.
These findings suggest that patients with rosacea may have higher vitamin D levels, and it raises the question of whether elevated vitamin D could be contributing to the condition. Nevertheless, more extensive studies are necessary to clarify the role of vitamin D in rosacea, as our research was the first of its kind to investigate this relationship. We acknowledge the need for further investigation to confirm these results and understand the implications better.
Read More
8
We investigated the relationship between vitamin D levels and the risk of developing rosacea, a common skin condition characterized by redness and visible blood vessels. Our study utilized data from the UK Biobank, which included over 370,000 individuals.
We found that higher serum levels of 25-hydroxyvitamin D (25OHD) were linked to a reduced risk of incident rosacea. For instance, participants with 25OHD levels above 50 nmol/L had a lower risk compared to those with levels below 25 nmol/L.
In particular, those with levels higher than 75 nmol/L and specific genetic variants were even less likely to develop rosacea. Our findings suggest a potential protective effect of vitamin D, indicating that maintaining adequate levels might help reduce the likelihood of this skin condition.
However, the study does not evaluate the efficacy of vitamin D supplementation as a direct treatment for rosacea. More research is needed to fully understand how vitamin D might serve as a preventive strategy.
We found that higher serum levels of 25-hydroxyvitamin D (25OHD) were linked to a reduced risk of incident rosacea. For instance, participants with 25OHD levels above 50 nmol/L had a lower risk compared to those with levels below 25 nmol/L.
In particular, those with levels higher than 75 nmol/L and specific genetic variants were even less likely to develop rosacea. Our findings suggest a potential protective effect of vitamin D, indicating that maintaining adequate levels might help reduce the likelihood of this skin condition.
However, the study does not evaluate the efficacy of vitamin D supplementation as a direct treatment for rosacea. More research is needed to fully understand how vitamin D might serve as a preventive strategy.
Read More
Most Useful Reviews
9
Skin hydration improvement
Highly active vitamin D3 5000 has greatly improved my skin's dryness and flaking, even on my face where I have rosacea. My complexion feels toned, swelling has reduced, and the fragility of my leg blood vessels has diminished. My sleep has also improved.
Read More
9
Protects skin health
Vitamin D3 serves a significant role for the skin, protecting it from UV damage and photoaging. It supports microbial defence and enhances cell health, which is vital for my rosacea and other skin conditions.
Read More
7.5
Soothes dry skin
This product has yielded beautiful results from the start. It alleviates my very dry, sensitive skin affected by rosacea. I recommend using a small amount due to its heavy texture. The luxurious packaging and included spoon were delightful.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
5.3
- All Researches
8
We investigated the relationship between vitamin D levels and the risk of developing rosacea, a common skin condition characterized by redness and visible blood vessels. Our study utilized data from the UK Biobank, which included over 370,000 individuals.
We found that higher serum levels of 25-hydroxyvitamin D (25OHD) were linked to a reduced risk of incident rosacea. For instance, participants with 25OHD levels above 50 nmol/L had a lower risk compared to those with levels below 25 nmol/L.
In particular, those with levels higher than 75 nmol/L and specific genetic variants were even less likely to develop rosacea. Our findings suggest a potential protective effect of vitamin D, indicating that maintaining adequate levels might help reduce the likelihood of this skin condition.
However, the study does not evaluate the efficacy of vitamin D supplementation as a direct treatment for rosacea. More research is needed to fully understand how vitamin D might serve as a preventive strategy.
We found that higher serum levels of 25-hydroxyvitamin D (25OHD) were linked to a reduced risk of incident rosacea. For instance, participants with 25OHD levels above 50 nmol/L had a lower risk compared to those with levels below 25 nmol/L.
In particular, those with levels higher than 75 nmol/L and specific genetic variants were even less likely to develop rosacea. Our findings suggest a potential protective effect of vitamin D, indicating that maintaining adequate levels might help reduce the likelihood of this skin condition.
However, the study does not evaluate the efficacy of vitamin D supplementation as a direct treatment for rosacea. More research is needed to fully understand how vitamin D might serve as a preventive strategy.
Read More
4
We designed a fascinating case-control study to investigate how vitamin D might influence the risk of developing rosacea, a common skin condition. In our research, we compared patients who have rosacea to healthy individuals, assessing their vitamin D levels and specific variations in their vitamin D receptor genes.
The findings indicated that patients with rosacea had notably higher levels of serum 25-hydroxyvitamin D. In fact, those with elevated vitamin D levels had a 1.36-fold increased risk of developing rosacea. We also discovered that certain genetic variations, such as the ApaI and TaqI polymorphisms, played a significant role in rosacea susceptibility, with heterozygous and mutant forms of the ApaI variants particularly increasing risk.
These results suggest that vitamin D and its receptor pathways may be contributing factors in rosacea development. However, it’s important to note that while these associations are compelling, causality remains unclear, meaning we cannot conclude that vitamin D treatment will definitively affect rosacea outcomes.
The findings indicated that patients with rosacea had notably higher levels of serum 25-hydroxyvitamin D. In fact, those with elevated vitamin D levels had a 1.36-fold increased risk of developing rosacea. We also discovered that certain genetic variations, such as the ApaI and TaqI polymorphisms, played a significant role in rosacea susceptibility, with heterozygous and mutant forms of the ApaI variants particularly increasing risk.
These results suggest that vitamin D and its receptor pathways may be contributing factors in rosacea development. However, it’s important to note that while these associations are compelling, causality remains unclear, meaning we cannot conclude that vitamin D treatment will definitively affect rosacea outcomes.
Read More
4
We explored the connection between vitamin D levels and rosacea by comparing serum vitamin D in patients with this skin condition to healthy individuals. Our study included 44 rosacea patients and 32 controls, with the aim of understanding whether vitamin D plays a role in the development of rosacea.
Interestingly, we found that the average vitamin D levels were higher in the rosacea patients (21.4 ng/ml) compared to the control group (17.1 ng/ml), a difference that was statistically significant. However, when looking at vitamin D deficiency, the prevalence was quite similar between the two groups—38.6% of rosacea patients were deficient compared to 28.1% of healthy controls.
These findings suggest that patients with rosacea may have higher vitamin D levels, and it raises the question of whether elevated vitamin D could be contributing to the condition. Nevertheless, more extensive studies are necessary to clarify the role of vitamin D in rosacea, as our research was the first of its kind to investigate this relationship. We acknowledge the need for further investigation to confirm these results and understand the implications better.
Interestingly, we found that the average vitamin D levels were higher in the rosacea patients (21.4 ng/ml) compared to the control group (17.1 ng/ml), a difference that was statistically significant. However, when looking at vitamin D deficiency, the prevalence was quite similar between the two groups—38.6% of rosacea patients were deficient compared to 28.1% of healthy controls.
These findings suggest that patients with rosacea may have higher vitamin D levels, and it raises the question of whether elevated vitamin D could be contributing to the condition. Nevertheless, more extensive studies are necessary to clarify the role of vitamin D in rosacea, as our research was the first of its kind to investigate this relationship. We acknowledge the need for further investigation to confirm these results and understand the implications better.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Skin hydration improvement
Highly active vitamin D3 5000 has greatly improved my skin's dryness and flaking, even on my face where I have rosacea. My complexion feels toned, swelling has reduced, and the fragility of my leg blood vessels has diminished. My sleep has also improved.
Read More
9
Protects skin health
Vitamin D3 serves a significant role for the skin, protecting it from UV damage and photoaging. It supports microbial defence and enhances cell health, which is vital for my rosacea and other skin conditions.
Read More
7.5
Soothes dry skin
This product has yielded beautiful results from the start. It alleviates my very dry, sensitive skin affected by rosacea. I recommend using a small amount due to its heavy texture. The luxurious packaging and included spoon were delightful.
Read More
7.5
Effective for rosacea
This great product comes highly recommended. I appreciate that it lacks harmful additives. It has positively affected my rosacea, especially when taken with vitamin K2, and offers excellent value for the price.
Read More
Frequently Asked Questions
7.5
Soothes dry skin
This product has yielded beautiful results from the start. It alleviates my very dry, sensitive skin affected by rosacea. I recommend using a small amount due to its heavy texture. The luxurious packaging and included spoon were delightful.
9
Skin hydration improvement
Highly active vitamin D3 5000 has greatly improved my skin's dryness and flaking, even on my face where I have rosacea. My complexion feels toned, swelling has reduced, and the fragility of my leg blood vessels has diminished. My sleep has also improved.
9
Protects skin health
Vitamin D3 serves a significant role for the skin, protecting it from UV damage and photoaging. It supports microbial defence and enhances cell health, which is vital for my rosacea and other skin conditions.
7.5
Effective for rosacea
This great product comes highly recommended. I appreciate that it lacks harmful additives. It has positively affected my rosacea, especially when taken with vitamin K2, and offers excellent value for the price.
8
We investigated the relationship between vitamin D levels and the risk of developing rosacea, a common skin condition characterized by redness and visible blood vessels. Our study utilized data from the UK Biobank, which included over 370,000 individuals.
We found that higher serum levels of 25-hydroxyvitamin D (25OHD) were linked to a reduced risk of incident rosacea. For instance, participants with 25OHD levels above 50 nmol/L had a lower risk compared to those with levels below 25 nmol/L.
In particular, those with levels higher than 75 nmol/L and specific genetic variants were even less likely to develop rosacea. Our findings suggest a potential protective effect of vitamin D, indicating that maintaining adequate levels might help reduce the likelihood of this skin condition.
However, the study does not evaluate the efficacy of vitamin D supplementation as a direct treatment for rosacea. More research is needed to fully understand how vitamin D might serve as a preventive strategy.
We found that higher serum levels of 25-hydroxyvitamin D (25OHD) were linked to a reduced risk of incident rosacea. For instance, participants with 25OHD levels above 50 nmol/L had a lower risk compared to those with levels below 25 nmol/L.
In particular, those with levels higher than 75 nmol/L and specific genetic variants were even less likely to develop rosacea. Our findings suggest a potential protective effect of vitamin D, indicating that maintaining adequate levels might help reduce the likelihood of this skin condition.
However, the study does not evaluate the efficacy of vitamin D supplementation as a direct treatment for rosacea. More research is needed to fully understand how vitamin D might serve as a preventive strategy.
4
We designed a fascinating case-control study to investigate how vitamin D might influence the risk of developing rosacea, a common skin condition. In our research, we compared patients who have rosacea to healthy individuals, assessing their vitamin D levels and specific variations in their vitamin D receptor genes.
The findings indicated that patients with rosacea had notably higher levels of serum 25-hydroxyvitamin D. In fact, those with elevated vitamin D levels had a 1.36-fold increased risk of developing rosacea. We also discovered that certain genetic variations, such as the ApaI and TaqI polymorphisms, played a significant role in rosacea susceptibility, with heterozygous and mutant forms of the ApaI variants particularly increasing risk.
These results suggest that vitamin D and its receptor pathways may be contributing factors in rosacea development. However, it’s important to note that while these associations are compelling, causality remains unclear, meaning we cannot conclude that vitamin D treatment will definitively affect rosacea outcomes.
The findings indicated that patients with rosacea had notably higher levels of serum 25-hydroxyvitamin D. In fact, those with elevated vitamin D levels had a 1.36-fold increased risk of developing rosacea. We also discovered that certain genetic variations, such as the ApaI and TaqI polymorphisms, played a significant role in rosacea susceptibility, with heterozygous and mutant forms of the ApaI variants particularly increasing risk.
These results suggest that vitamin D and its receptor pathways may be contributing factors in rosacea development. However, it’s important to note that while these associations are compelling, causality remains unclear, meaning we cannot conclude that vitamin D treatment will definitively affect rosacea outcomes.
4
We explored the connection between vitamin D levels and rosacea by comparing serum vitamin D in patients with this skin condition to healthy individuals. Our study included 44 rosacea patients and 32 controls, with the aim of understanding whether vitamin D plays a role in the development of rosacea.
Interestingly, we found that the average vitamin D levels were higher in the rosacea patients (21.4 ng/ml) compared to the control group (17.1 ng/ml), a difference that was statistically significant. However, when looking at vitamin D deficiency, the prevalence was quite similar between the two groups—38.6% of rosacea patients were deficient compared to 28.1% of healthy controls.
These findings suggest that patients with rosacea may have higher vitamin D levels, and it raises the question of whether elevated vitamin D could be contributing to the condition. Nevertheless, more extensive studies are necessary to clarify the role of vitamin D in rosacea, as our research was the first of its kind to investigate this relationship. We acknowledge the need for further investigation to confirm these results and understand the implications better.
Interestingly, we found that the average vitamin D levels were higher in the rosacea patients (21.4 ng/ml) compared to the control group (17.1 ng/ml), a difference that was statistically significant. However, when looking at vitamin D deficiency, the prevalence was quite similar between the two groups—38.6% of rosacea patients were deficient compared to 28.1% of healthy controls.
These findings suggest that patients with rosacea may have higher vitamin D levels, and it raises the question of whether elevated vitamin D could be contributing to the condition. Nevertheless, more extensive studies are necessary to clarify the role of vitamin D in rosacea, as our research was the first of its kind to investigate this relationship. We acknowledge the need for further investigation to confirm these results and understand the implications better.
References
- Mao R, Zhou G, Jing D, Liu H, Shen M, et al. Vitamin D Status, Vitamin D Receptor Polymorphisms, and the Risk of Incident Rosacea: Insights from Mendelian Randomization and Cohort Study in the UK Biobank. Nutrients. 2023;15. doi:10.3390/nu15173803
- Akdogan N, Alli N, Incel Uysal P, Candar T. Role of serum 25-hydroxyvitamin D levels and vitamin D receptor gene polymorphisms in patients with rosacea: a case-control study. Clin Exp Dermatol. 2019;44:397. doi:10.1111/ced.13769
- Ekiz O, Balta I, Sen BB, Dikilitaş MC, Ozuğuz P, et al. Vitamin D status in patients with rosacea. Cutan Ocul Toxicol. 2014;33:60. doi:10.3109/15569527.2013.797907
