Last update
5/25/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 5 Reviews
8.1
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%
Top Medical Research Studies
8
We explored the connection between vitamin D levels and immunity to varicella-zoster virus (VZV), which causes shingles, in patients undergoing chronic dialysis. Recognizing that these patients often have weakened immune systems, we set out to see if vitamin D could play a vital role in boosting their immunity.
In a multicenter study involving 88 hemodialysis patients, we measured various vitamin D parameters in their blood and assessed their VZV immunity through specific antibody tests. The results were telling: patients with a vitamin D level of less than 30 ng/ml had significantly lower levels of VZV-specific IgG antibodies compared to those who had sufficient vitamin D. This difference became more pronounced when focusing on patients who were actively using vitamin D supplements.
We found that having a higher level of vitamin D was associated with increased immunity against VZV, highlighting a potential link between vitamin D treatments and shingles prevention. Our findings suggest that boosting vitamin D in chronic dialysis patients could be an effective strategy to enhance their immune response to shingles and, potentially, improve their overall health. However, patients with cancer in the study exhibited lower VZV immunity, indicating that other factors could also influence results.
In a multicenter study involving 88 hemodialysis patients, we measured various vitamin D parameters in their blood and assessed their VZV immunity through specific antibody tests. The results were telling: patients with a vitamin D level of less than 30 ng/ml had significantly lower levels of VZV-specific IgG antibodies compared to those who had sufficient vitamin D. This difference became more pronounced when focusing on patients who were actively using vitamin D supplements.
We found that having a higher level of vitamin D was associated with increased immunity against VZV, highlighting a potential link between vitamin D treatments and shingles prevention. Our findings suggest that boosting vitamin D in chronic dialysis patients could be an effective strategy to enhance their immune response to shingles and, potentially, improve their overall health. However, patients with cancer in the study exhibited lower VZV immunity, indicating that other factors could also influence results.
Read More
9
We observed the impact of vitamin D and other factors on the reactivation of herpes zoster (commonly known as shingles) among patients undergoing maintenance hemodialysis. The study included patients who had been on hemodialysis for more than three months and identified those who developed shingles from 2000 to 2009.
By matching these patients with others of similar age and gender who did not experience shingles, we sought to pinpoint factors influencing the likelihood of shingles reactivation. Our findings indicated a strong correlation between the use of corticosteroids and an increased risk of developing shingles.
On a more positive note, we noted that patients taking iron preparations and 1α-hydroxylated vitamin D had a significantly reduced risk of experiencing shingles. This suggests that these treatments could play a protective role for hemodialysis patients against the reactivation of this virus.
Overall, while the role of vitamin D is part of a larger picture, it appears to contribute to reducing the risk of shingles among those in this vulnerable group.
By matching these patients with others of similar age and gender who did not experience shingles, we sought to pinpoint factors influencing the likelihood of shingles reactivation. Our findings indicated a strong correlation between the use of corticosteroids and an increased risk of developing shingles.
On a more positive note, we noted that patients taking iron preparations and 1α-hydroxylated vitamin D had a significantly reduced risk of experiencing shingles. This suggests that these treatments could play a protective role for hemodialysis patients against the reactivation of this virus.
Overall, while the role of vitamin D is part of a larger picture, it appears to contribute to reducing the risk of shingles among those in this vulnerable group.
Read More
Most Useful Reviews
7
Boosts immunity
3 people found this helpful
Every year, I take it to prevent winter colds. My immunity seems to drop with stress, leading to frequent colds which I recover from, only to catch them again. Remarkably, I haven't caught a cold this season. When my family feels exhausted and is on the verge of developing shingles, I take it easy for a while until things settle down. It appears that I will manage to get through this with boosted immunity. The tablets are small, easy to swallow, tasteless, and odourless. In Japan, the recommended daily intake of Vitamin D is 8.5 mg for adults, with a tolerable upper limit of 100 mg. Since excessive intake can cause hypercalcemia, I opt for one tablet (125 micrograms) every other day as a safer approach.
Read More
8
Significant improvement
My wife has suffered from shingles for the past 12 months. The vitamin D-3 has significantly helped her overcome various issues, and I am also taking it as I recover from surgery.
Read More
8
Supports recovery
I purchased this after experiencing nerve damage from shingles. It works wonders in aiding my recovery.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
We observed the impact of vitamin D and other factors on the reactivation of herpes zoster (commonly known as shingles) among patients undergoing maintenance hemodialysis. The study included patients who had been on hemodialysis for more than three months and identified those who developed shingles from 2000 to 2009.
By matching these patients with others of similar age and gender who did not experience shingles, we sought to pinpoint factors influencing the likelihood of shingles reactivation. Our findings indicated a strong correlation between the use of corticosteroids and an increased risk of developing shingles.
On a more positive note, we noted that patients taking iron preparations and 1α-hydroxylated vitamin D had a significantly reduced risk of experiencing shingles. This suggests that these treatments could play a protective role for hemodialysis patients against the reactivation of this virus.
Overall, while the role of vitamin D is part of a larger picture, it appears to contribute to reducing the risk of shingles among those in this vulnerable group.
By matching these patients with others of similar age and gender who did not experience shingles, we sought to pinpoint factors influencing the likelihood of shingles reactivation. Our findings indicated a strong correlation between the use of corticosteroids and an increased risk of developing shingles.
On a more positive note, we noted that patients taking iron preparations and 1α-hydroxylated vitamin D had a significantly reduced risk of experiencing shingles. This suggests that these treatments could play a protective role for hemodialysis patients against the reactivation of this virus.
Overall, while the role of vitamin D is part of a larger picture, it appears to contribute to reducing the risk of shingles among those in this vulnerable group.
Read More
8
We explored the connection between vitamin D levels and immunity to varicella-zoster virus (VZV), which causes shingles, in patients undergoing chronic dialysis. Recognizing that these patients often have weakened immune systems, we set out to see if vitamin D could play a vital role in boosting their immunity.
In a multicenter study involving 88 hemodialysis patients, we measured various vitamin D parameters in their blood and assessed their VZV immunity through specific antibody tests. The results were telling: patients with a vitamin D level of less than 30 ng/ml had significantly lower levels of VZV-specific IgG antibodies compared to those who had sufficient vitamin D. This difference became more pronounced when focusing on patients who were actively using vitamin D supplements.
We found that having a higher level of vitamin D was associated with increased immunity against VZV, highlighting a potential link between vitamin D treatments and shingles prevention. Our findings suggest that boosting vitamin D in chronic dialysis patients could be an effective strategy to enhance their immune response to shingles and, potentially, improve their overall health. However, patients with cancer in the study exhibited lower VZV immunity, indicating that other factors could also influence results.
In a multicenter study involving 88 hemodialysis patients, we measured various vitamin D parameters in their blood and assessed their VZV immunity through specific antibody tests. The results were telling: patients with a vitamin D level of less than 30 ng/ml had significantly lower levels of VZV-specific IgG antibodies compared to those who had sufficient vitamin D. This difference became more pronounced when focusing on patients who were actively using vitamin D supplements.
We found that having a higher level of vitamin D was associated with increased immunity against VZV, highlighting a potential link between vitamin D treatments and shingles prevention. Our findings suggest that boosting vitamin D in chronic dialysis patients could be an effective strategy to enhance their immune response to shingles and, potentially, improve their overall health. However, patients with cancer in the study exhibited lower VZV immunity, indicating that other factors could also influence results.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.1
- All Reviews
- Positive Reviews
- Negative Reviews
7
Boosts immunity
3 people found this helpful
Every year, I take it to prevent winter colds. My immunity seems to drop with stress, leading to frequent colds which I recover from, only to catch them again. Remarkably, I haven't caught a cold this season. When my family feels exhausted and is on the verge of developing shingles, I take it easy for a while until things settle down. It appears that I will manage to get through this with boosted immunity. The tablets are small, easy to swallow, tasteless, and odourless. In Japan, the recommended daily intake of Vitamin D is 8.5 mg for adults, with a tolerable upper limit of 100 mg. Since excessive intake can cause hypercalcemia, I opt for one tablet (125 micrograms) every other day as a safer approach.
Read More
8
Significant improvement
My wife has suffered from shingles for the past 12 months. The vitamin D-3 has significantly helped her overcome various issues, and I am also taking it as I recover from surgery.
Read More
8
Supports recovery
I purchased this after experiencing nerve damage from shingles. It works wonders in aiding my recovery.
Read More
7
Effective treatment
I increased my dosage from 2000mcg to 5000mcg, taking it once daily without issues. The pills are small and easy to swallow. The 2000mcg vitamin D supplement helped to calm my shingles, so I will continue with this treatment.
Read More
6
Effective for shingles
In winter, you simply can't manage without it! My entire family takes 5000 units, and I personally take 10,000 units to help with my herpes zoster.
Read More
Frequently Asked Questions
8
Significant improvement
My wife has suffered from shingles for the past 12 months. The vitamin D-3 has significantly helped her overcome various issues, and I am also taking it as I recover from surgery.
8
Supports recovery
I purchased this after experiencing nerve damage from shingles. It works wonders in aiding my recovery.
7
Effective treatment
I increased my dosage from 2000mcg to 5000mcg, taking it once daily without issues. The pills are small and easy to swallow. The 2000mcg vitamin D supplement helped to calm my shingles, so I will continue with this treatment.
8
We explored the connection between vitamin D levels and immunity to varicella-zoster virus (VZV), which causes shingles, in patients undergoing chronic dialysis. Recognizing that these patients often have weakened immune systems, we set out to see if vitamin D could play a vital role in boosting their immunity.
In a multicenter study involving 88 hemodialysis patients, we measured various vitamin D parameters in their blood and assessed their VZV immunity through specific antibody tests. The results were telling: patients with a vitamin D level of less than 30 ng/ml had significantly lower levels of VZV-specific IgG antibodies compared to those who had sufficient vitamin D. This difference became more pronounced when focusing on patients who were actively using vitamin D supplements.
We found that having a higher level of vitamin D was associated with increased immunity against VZV, highlighting a potential link between vitamin D treatments and shingles prevention. Our findings suggest that boosting vitamin D in chronic dialysis patients could be an effective strategy to enhance their immune response to shingles and, potentially, improve their overall health. However, patients with cancer in the study exhibited lower VZV immunity, indicating that other factors could also influence results.
In a multicenter study involving 88 hemodialysis patients, we measured various vitamin D parameters in their blood and assessed their VZV immunity through specific antibody tests. The results were telling: patients with a vitamin D level of less than 30 ng/ml had significantly lower levels of VZV-specific IgG antibodies compared to those who had sufficient vitamin D. This difference became more pronounced when focusing on patients who were actively using vitamin D supplements.
We found that having a higher level of vitamin D was associated with increased immunity against VZV, highlighting a potential link between vitamin D treatments and shingles prevention. Our findings suggest that boosting vitamin D in chronic dialysis patients could be an effective strategy to enhance their immune response to shingles and, potentially, improve their overall health. However, patients with cancer in the study exhibited lower VZV immunity, indicating that other factors could also influence results.
9
We observed the impact of vitamin D and other factors on the reactivation of herpes zoster (commonly known as shingles) among patients undergoing maintenance hemodialysis. The study included patients who had been on hemodialysis for more than three months and identified those who developed shingles from 2000 to 2009.
By matching these patients with others of similar age and gender who did not experience shingles, we sought to pinpoint factors influencing the likelihood of shingles reactivation. Our findings indicated a strong correlation between the use of corticosteroids and an increased risk of developing shingles.
On a more positive note, we noted that patients taking iron preparations and 1α-hydroxylated vitamin D had a significantly reduced risk of experiencing shingles. This suggests that these treatments could play a protective role for hemodialysis patients against the reactivation of this virus.
Overall, while the role of vitamin D is part of a larger picture, it appears to contribute to reducing the risk of shingles among those in this vulnerable group.
By matching these patients with others of similar age and gender who did not experience shingles, we sought to pinpoint factors influencing the likelihood of shingles reactivation. Our findings indicated a strong correlation between the use of corticosteroids and an increased risk of developing shingles.
On a more positive note, we noted that patients taking iron preparations and 1α-hydroxylated vitamin D had a significantly reduced risk of experiencing shingles. This suggests that these treatments could play a protective role for hemodialysis patients against the reactivation of this virus.
Overall, while the role of vitamin D is part of a larger picture, it appears to contribute to reducing the risk of shingles among those in this vulnerable group.
References
- Chao CT, Lee SY, Yang WS, Yen CJ, Chiang CK, et al. Serum vitamin D levels are positively associated with varicella zoster immunity in chronic dialysis patients. Sci Rep. 2014;4:7371. 10.1038/srep07371
- Chao CT, Lai CF, Huang JW. Risk factors for herpes zoster reactivation in maintenance hemodialysis patients. Eur J Intern Med. 2012;23:711. 10.1016/j.ejim.2012.08.005
