We conducted a clinical trial to explore the effectiveness of intralesional vitamin D3 as a treatment for cutaneous warts. Involving 40 patients, we injected a vitamin D3 solution into the bases of their warts over several sessions.
The results were promising, with 81.9% achieving complete clearance of their warts after treatment, while only a small percentage showed no improvement. Most patients tolerated the treatment well, reporting only minor side effects.
Overall, vitamin D3 proves to be an effective and affordable option for wart treatment.
Read More
9.5
Vitamin D3 shows promise for warts
Complete clearance of condyloma acuminata using injection Vitamin D3.
We investigated the effectiveness of vitamin D3 injections for treating anogenital warts, specifically condyloma acuminata. In a reported case, one male patient showed complete clearance of warts after this novel treatment.
Remarkably, there were no signs of recurrence during the six-month follow-up. This suggests that vitamin D3 could be a promising alternative to traditional, more cumbersome treatments that often require multiple sessions.
Read More
9
Vitamin D effectively treats warts
Immunotherapy with Intralesional Vit D injection in Recalcitrant wart at a Tertiary Care Center: A Descriptive Cross sectional Study.
We aimed to evaluate the effectiveness of intralesional vitamin D injections in treating stubborn warts. Our study included 92 patients, where vitamin D was injected directly into the base of the warts over three sessions.
Results showed that 76% of participants experienced complete disappearance of their warts, with another 18% seeing partial improvement. The treatment was not only effective but also cost-efficient, and side effects were minimal.
This findings suggest that vitamin D injections could be a promising approach for those seeking alternatives to conventional wart treatments.
Read More
Most Useful Reviews
10
Leg wart gone!
Excellent! This vitamin D works wonders. My whole family takes it, and my husband had a wart on his leg that completely disappeared after taking the vitamin.
Read More
9
Warts fell off!
This is not the first time we've ordered this D3. We take it as a family, including my retired parents. The dosage works well and the results are evident! Prior to starting, my wife's D3 level was at 12 and after three months, it rose dramatically. She noticed she began to sleep better and felt more energetic, and significantly, about five warts on her hands fell off on their own! We highly recommend this D3!
Read More
9
Effective treatment!
This is the best D3! We continually order it now in 240 capsule bottles. The dosage is excellent and the results are visible! We took tests before starting and found my wife's D3 level was 12, which tripled after three months. She also noticed better sleep and increased energy, which is great, but most importantly, five warts on her hands just fell off! We wholeheartedly recommend this D3!
Topical Vitamin D Derivative (Calcipotriol) Versus Intralesional Vitamin D in the Treatment of Cutaneous Warts: A Clinical Therapeutic Comparative Trial.
We explored the effectiveness of two forms of vitamin D in treating cutaneous warts: a topical ointment and an intralesional injection. In a study with 56 participants, results showed the topical treatment had a higher success rate, with 95% of patients responding completely compared to 59% in the injection group.
Furthermore, the topical group experienced fewer side effects and no recurrences, while some patients in the injection group faced challenges post-treatment. Overall, topical vitamin D appears to be the more effective option for wart treatment.
Read More
9.5
Vitamin D3 effectively treats warts
The efficacy of intralesional vitamin D3 injection in the treatment of cutaneous warts: A clinical therapeutic trial study.
We conducted a clinical trial to explore the effectiveness of intralesional vitamin D3 as a treatment for cutaneous warts. Involving 40 patients, we injected a vitamin D3 solution into the bases of their warts over several sessions.
The results were promising, with 81.9% achieving complete clearance of their warts after treatment, while only a small percentage showed no improvement. Most patients tolerated the treatment well, reporting only minor side effects.
Overall, vitamin D3 proves to be an effective and affordable option for wart treatment.
Read More
9.5
Vitamin D3 shows promise for warts
Complete clearance of condyloma acuminata using injection Vitamin D3.
We investigated the effectiveness of vitamin D3 injections for treating anogenital warts, specifically condyloma acuminata. In a reported case, one male patient showed complete clearance of warts after this novel treatment.
Remarkably, there were no signs of recurrence during the six-month follow-up. This suggests that vitamin D3 could be a promising alternative to traditional, more cumbersome treatments that often require multiple sessions.
Read More
9
Vitamin D effectively treats warts
Immunotherapy with Intralesional Vit D injection in Recalcitrant wart at a Tertiary Care Center: A Descriptive Cross sectional Study.
We aimed to evaluate the effectiveness of intralesional vitamin D injections in treating stubborn warts. Our study included 92 patients, where vitamin D was injected directly into the base of the warts over three sessions.
Results showed that 76% of participants experienced complete disappearance of their warts, with another 18% seeing partial improvement. The treatment was not only effective but also cost-efficient, and side effects were minimal.
This findings suggest that vitamin D injections could be a promising approach for those seeking alternatives to conventional wart treatments.
Read More
9
Vitamin D3 shows promise for warts
Emerging Intralesional Treatments for Plantar Warts: A Systematic Review.
We investigated various treatments for plantar warts, particularly focusing on the effectiveness of intralesional vitamin D3. According to our review of 26 studies, vitamin D3 showed promise, boasting a median cure rate of 80%.
While other options like bleomycin and Candida antigen were less effective, they remain viable alternatives due to their availability. Intralesional vitamin D3 stands out as a potential first-line treatment, though it is not currently accessible in the U.S.
Additionally, we noted that the HPV vaccine deserves attention for both treating and preventing these warts.
Excellent! This vitamin D works wonders. My whole family takes it, and my husband had a wart on his leg that completely disappeared after taking the vitamin.
Read More
9
Warts fell off!
This is not the first time we've ordered this D3. We take it as a family, including my retired parents. The dosage works well and the results are evident! Prior to starting, my wife's D3 level was at 12 and after three months, it rose dramatically. She noticed she began to sleep better and felt more energetic, and significantly, about five warts on her hands fell off on their own! We highly recommend this D3!
Read More
9
Effective treatment!
This is the best D3! We continually order it now in 240 capsule bottles. The dosage is excellent and the results are visible! We took tests before starting and found my wife's D3 level was 12, which tripled after three months. She also noticed better sleep and increased energy, which is great, but most importantly, five warts on her hands just fell off! We wholeheartedly recommend this D3!
Read More
9
Visible improvement!
Excellent vitamin! Within a week, the effects were noticeable; my skin improved and a wart that I'd struggled with in various ways vanished. The price-to-quality ratio is superb, essential for those who work indoors and only see the sun through a window.
Read More
9
No more colds!
It truly works! An excellent product! After starting treatment, a wart on my index finger disappeared on its own! My immunity improved significantly, and I haven’t had colds for the whole year. I always choose this brand of vitamin D3 and I’m thrilled with the results. Highly recommended!
Warts are small, non-cancerous growths on the skin caused by the human papillomavirus (HPV). They can occur on various parts of the body, including the hands, feet, and face. Warts typically present as raised bumps with a rough surface, and they can be flesh-colored or dark brown in appearance. Some common types of warts include common warts (usually found on fingers), plantar warts (found on the soles of the feet), and flat warts (which are smaller and can appear in groups). While warts are generally harmless and may go away on their own, they can be bothersome or embarrassing, prompting individuals to seek treatment.
The transmission of the virus that causes warts can occur through direct skin contact or indirectly through contact with surfaces that have been contaminated. While anyone can develop warts, certain factors such as a weakened immune system or broken skin can increase the risk. Various treatment options are available, ranging from over-the-counter topical medications to professional treatments like cryotherapy (freezing the wart), laser therapy, or surgical removal. If you're considering treatment, it's advisable to consult with a healthcare professional to determine the most suitable option for your particular case of warts.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
Based on user reviews, the timeframe for seeing results when taking vitamin D3 for warts can vary, but several users report improvements in a short span of time. For instance, one reviewer noted that a wart they had struggled with vanished within just a week of starting the supplement Read Review. Another user mentioned that within a month of treatment, they no longer had to worry about their warts Read Review.
Additionally, other users have indicated positive results after a period of three months, with multiple warts disappearing on their own during that timeframe Read ReviewRead Review. Overall, while some individuals noticed results quickly, others experienced them over a longer duration, making it reasonable to expect varying results depending on personal conditions and the extent of the warts.
The scientific research surrounding Vitamin D as a treatment for warts presents a mix of promising results and varying effectiveness. Several studies have highlighted Vitamin D's potential, particularly in its intralesional injection form. For instance, a randomized study revealed that approximately 76% of participants experienced complete wart disappearance following vitamin D injections, which underscores its effectiveness for stubborn warts [3]. Additionally, other research emphasizes the success of topical Vitamin D, which resulted in a 95% response rate for patients [2].
However, not all studies paint a uniformly favorable picture. Some trials indicate that while Vitamin D3 shows a moderate success rate, it does not surpass alternative treatments like Candida antigen or cryotherapy [14][13]. Moreover, a study found no significant difference in effectiveness between Vitamin D treatments and placebo, suggesting it may not be as beneficial as previously thought [9]. Overall, while Vitamin D can be a viable option in some contexts, particularly for those looking for alternatives to conventional wart treatments, it may not be the definitive solution for everyone.
Users have reported a range of notable improvements in their symptoms after taking vitamin D3, particularly concerning warts. Many reviewers shared positive experiences, highlighting that warts they had struggled with for an extended period disappeared following the use of the supplement. For example, one user noted that their husband's wart vanished after beginning vitamin D3 treatment Read Review. Another reviewer shared that multiple warts on their spouse's hands fell off within three months of treatment Read Review.
Additionally, several users reported improvements in their overall health, with increased energy levels and better sleep quality accompanying the reduction in warts. One user remarked that after taking the vitamin, they experienced a significant boost in immunity, leading to fewer colds throughout the year Read Review. While these experiences are promising, it's worth noting that individual results can vary significantly based on personal health conditions and circumstances.
Based on user reviews, many individuals reported positive experiences when combining vitamin D3 with other supplements to handle warts. For instance, one user noted that their husband took vitamin C along with vitamin D3 and omega-800, leading to a significant reduction in warts within a month, as well as fewer respiratory infections Read Review. Another review shared that a user experienced successful wart removal while taking vitamin D along with omega, which resulted in warts on both their heel and hand vanishing Read Review.
Moreover, users emphasized the importance of consulting a doctor before starting any supplement regimen to address warts, as the combination of different supplements can yield varying results depending on individual health conditions. Overall, reviews suggest that combining vitamin D3 with such supplements may enhance effectiveness, leading to a more significant reduction in warts alongside improving general immunity and health.
Users report a variety of positive outcomes when using Vitamin D for treating warts, suggesting a potential effectiveness in reducing or eliminating them. Many users indicate that after taking Vitamin D, warts have disappeared without additional treatments. For instance, one user noted that after starting Vitamin D, five warts on her hands fell off on their own after three months of treatment Read Review. Another user shared that a persistent wart on their hand vanished within a week of beginning Vitamin D supplementation Read Review.
As for dosing, several users shared their experiences with different regimens, highlighting the importance of maintaining adequate Vitamin D levels. For example, one individual reported taking a tablet every two days and noticed positive results, including the disappearance of a facial wart Read Review. While specific dosages weren't mentioned in detail, users emphasized consistency in taking Vitamin D seemed to correlate with notable improvements, supporting the notion that appropriate dosing may be a factor in achieving the desired outcome of wart reduction.
9
Visible improvement!
Excellent vitamin! Within a week, the effects were noticeable; my skin improved and a wart that I'd struggled with in various ways vanished. The price-to-quality ratio is superb, essential for those who work indoors and only see the sun through a window.
9
No more warts!
I recommend this for anyone! My husband, who frequently suffered from respiratory infections and constant warts, took vitamin C along with D and omega 800. A month later, we no longer worried about his warts and he got sick much less often. Consult with a doctor before purchasing.
9
Warts fell off!
This is not the first time we've ordered this D3. We take it as a family, including my retired parents. The dosage works well and the results are evident! Prior to starting, my wife's D3 level was at 12 and after three months, it rose dramatically. She noticed she began to sleep better and felt more energetic, and significantly, about five warts on her hands fell off on their own! We highly recommend this D3!
9
Effective treatment!
This is the best D3! We continually order it now in 240 capsule bottles. The dosage is excellent and the results are visible! We took tests before starting and found my wife's D3 level was 12, which tripled after three months. She also noticed better sleep and increased energy, which is great, but most importantly, five warts on her hands just fell off! We wholeheartedly recommend this D3!
10
Leg wart gone!
Excellent! This vitamin D works wonders. My whole family takes it, and my husband had a wart on his leg that completely disappeared after taking the vitamin.
9
No more colds!
It truly works! An excellent product! After starting treatment, a wart on my index finger disappeared on its own! My immunity improved significantly, and I haven’t had colds for the whole year. I always choose this brand of vitamin D3 and I’m thrilled with the results. Highly recommended!
9
Warts completely gone!
I’m not sure if it’s a miracle, but after taking it with omega, my warts disappeared. I had them on my heel and hand since childhood; now they’ve all vanished. I drink it every few days.
7.5
Wart disappeared!
3 people found this helpful
A small piece, easy to swallow. I heard that vitamin D can reduce adverse reactions to vaccines, so I bought a few bottles and took one tablet every two days. Many girls fear exposure to the sun and are prone to vitamin D deficiency, so IHerbs offers the best quality. Additionally, I had warts on my face. A dermatologist mentioned that individuals lacking vitamin D are more likely to develop warts. Naturally, sunbathing is the ideal solution, but I was concerned about sunburn, so I purchased vitamin D instead. After a while of taking it, I noticed that a wart had disappeared on its own.
9
Vitamin D effectively treats warts
Immunotherapy with Intralesional Vit D injection in Recalcitrant wart at a Tertiary Care Center: A Descriptive Cross sectional Study.
We aimed to evaluate the effectiveness of intralesional vitamin D injections in treating stubborn warts. Our study included 92 patients, where vitamin D was injected directly into the base of the warts over three sessions.
Results showed that 76% of participants experienced complete disappearance of their warts, with another 18% seeing partial improvement. The treatment was not only effective but also cost-efficient, and side effects were minimal.
This findings suggest that vitamin D injections could be a promising approach for those seeking alternatives to conventional wart treatments.
9.5
Topical vitamin D outperforms injection
Topical Vitamin D Derivative (Calcipotriol) Versus Intralesional Vitamin D in the Treatment of Cutaneous Warts: A Clinical Therapeutic Comparative Trial.
We explored the effectiveness of two forms of vitamin D in treating cutaneous warts: a topical ointment and an intralesional injection. In a study with 56 participants, results showed the topical treatment had a higher success rate, with 95% of patients responding completely compared to 59% in the injection group.
Furthermore, the topical group experienced fewer side effects and no recurrences, while some patients in the injection group faced challenges post-treatment. Overall, topical vitamin D appears to be the more effective option for wart treatment.
2
Vitamin D3 less effective for warts
Intralesional Candida antigen versus intralesional vitamin D3 in the treatment of recalcitrant multiple common warts.
We tested two treatments for multiple common warts: intralesional Candida antigen and vitamin D3. In a study with 80 adults, participants received injections every three weeks for up to four sessions.
While Candida antigen showed impressive results, with a 76.7% clearance rate, vitamin D3 only achieved a 20% success rate. Importantly, the side effects were minimal for both treatments. Overall, our findings indicate that Candida antigen is a more effective option compared to vitamin D3 for treating stubborn warts.
We explored the effectiveness of intralesional vitamin D3 in treating cutaneous warts compared to cryotherapy in a randomized controlled trial involving 50 patients.
Both treatments showed promise, but we found that vitamin D3 led to a significantly higher rate of complete wart resolution.
The most common warts were plantar warts, seen predominantly on the feet. Our findings suggest that vitamin D3 might be a more effective option for managing these warts.
7
Vitamin D shows limited wart efficacy
A prospective randomized controlled study of Mycobacterium Indicus Pranii vaccine, Measles Mumps Rubella vaccine and Vitamin D3 in extragenital cutaneous warts.
We explored the effects of vitamin D in treating skin warts through a well-structured study involving 200 patients. Participants received injections of either vitamin D, a placebo, or other vaccines into their largest wart, monitored over several sessions.
Our findings revealed that the effectiveness of vitamin D was similar to that of the placebo, with only minor side effects reported. Both treatment groups experienced comparable rates of wart clearance, indicating that vitamin D may not be the solution many hoped for in wart treatment.
References
Shaafie HI, Koti VR, Saxena K, Shukla P. Intralesional immunotherapy of cutaneous warts using tuberculin purified protein derivative and vitamin D - A randomized comparative study. J Cutan Aesthet Surg. 2025;18:86. 10.25259/jcas_178_23
Almuhyi RA, Alhamdi KI, Alhamdi DK. Topical Vitamin D Derivative (Calcipotriol) Versus Intralesional Vitamin D in the Treatment of Cutaneous Warts: A Clinical Therapeutic Comparative Trial. Dermatol Res Pract. 2024;2024:5236290. 10.1155/2024/5236290
Aryal E, Bhari J, Shrestha PR. Immunotherapy with Intralesional Vit D injection in Recalcitrant wart at a Tertiary Care Center: A Descriptive Cross sectional Study. JNMA J Nepal Med Assoc. 2024;62:378. 10.31729/jnma.8614
Cao Y, Zhou X, Yang H. Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. Skin Res Technol. 2024;30:e13911. 10.1111/srt.13911
Noureen U, Shah RR, Waqas N, Sharif S, Shah A, et al. Efficacy of Intralesional Vitamin D3 for Treatment of Verruca Vulgaris: A Randomized Control Study. J Clin Aesthet Dermatol. 2023;16:47.
Al-Sabak H, Al-Hattab M, Al-Rammahi M, Al-Dhalimi M. The efficacy of intralesional vitamin D3 injection in the treatment of cutaneous warts: A clinical therapeutic trial study. Skin Res Technol. 2023;29:e13442. 10.1111/srt.13442
Chaudhary M, Brar A, Agarwal P, Chavda V, Jagati A, et al. A Study of Comparison and Evaluation of Various Intralesional Therapies in Cutaneous Warts. Indian Dermatol Online J. 2023;14:487. 10.4103/idoj.idoj_492_22
El Sharkawy DA, Nada HR, Radman Al-Kubati S. Comparative Study Among CO 2 Laser, Intralesional Vitamin D3, and Combined Intralesional Vitamin D3 and CO 2 Laser in Treatment of Palmoplantar Warts. Dermatol Surg. 2023;49:771. 10.1097/DSS.0000000000003846
Lahoria U, Singh S, Bhardwaj A, Budania A, Chhajed N, et al. A prospective randomized controlled study of Mycobacterium Indicus Pranii vaccine, Measles Mumps Rubella vaccine and Vitamin D3 in extragenital cutaneous warts. J Cosmet Dermatol. 2023;22:1400. 10.1111/jocd.15564
Nasr M, Abdelaty S, Elkholy BM. A comparative clinico-dermoscopic study of intralesional injection of combined digoxin and furosemide, Candida antigen, and vitamin D3 for multiple warts. J Cosmet Dermatol. 2023;22:1344. 10.1111/jocd.15581
Martin A, Thatiparthi A, Nourmohammadi N, Nguyen C, Sung C, et al. Emerging Intralesional Treatments for Plantar Warts: A Systematic Review. J Drugs Dermatol. 2022;21:1322. 10.36849/JDD.6735
Singh AK, Devi KN, Bist JS. A comparative evaluation of therapeutic response in warts to intralesional vitamin D3 versus intralesional measles, mumps, and rubella vaccine. Dermatol Ther. 2022;35:e15813. 10.1111/dth.15813
Zainab Z, Malik NA, Malik S, Mashhood A, Obaid S, et al. Role Of Intralesional Vitamin-D In Viral Wartse. J Ayub Med Coll Abbottabad. 2021;33:598.
Abdel Razik LH, Obaid ZM, Fouda I. Intralesional Candida antigen versus intralesional vitamin D3 in the treatment of recalcitrant multiple common warts. J Cosmet Dermatol. 2021;20:3341. 10.1111/jocd.14335
Abdelaal MA, Abdelaziz HM, Ahmed KA, Elsaie ML. Comparative Study of Intralesional Vitamin D3 Injection and Candida Albicans Antigen in Treating Plantar Warts. J Drugs Dermatol. 2021;20:546. 10.36849/JDD.5264
Jha N. Complete clearance of condyloma acuminata using injection Vitamin D3. Australas J Dermatol. 2021;62:e417. 10.1111/ajd.13586