Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
USERS' SCORE
Good
Based on 10 Reviews
8.7
Supplement Facts
Serving Size:   1 Softgel
Amount Per Serving
%DV
Vitamin D3 (as Cholecalciferol) (from Lanolin)
125 mcg (5,000 IU)
625%

Top Medical Research Studies

9.5
Vitamin D3 effectively treats warts
We conducted a clinical trial to explore the effectiveness of intralesional vitamin D3 as a treatment for cutaneous warts. Involving 40 patients, we injected a vitamin D3 solution into the bases of their warts over several sessions.

The results were promising, with 81.9% achieving complete clearance of their warts after treatment, while only a small percentage showed no improvement. Most patients tolerated the treatment well, reporting only minor side effects.

Overall, vitamin D3 proves to be an effective and affordable option for wart treatment.
Read More
9.5
Vitamin D3 shows promise for warts
We investigated the effectiveness of vitamin D3 injections for treating anogenital warts, specifically condyloma acuminata. In a reported case, one male patient showed complete clearance of warts after this novel treatment.

Remarkably, there were no signs of recurrence during the six-month follow-up. This suggests that vitamin D3 could be a promising alternative to traditional, more cumbersome treatments that often require multiple sessions.
Read More
9
Vitamin D effectively treats warts
We aimed to evaluate the effectiveness of intralesional vitamin D injections in treating stubborn warts. Our study included 92 patients, where vitamin D was injected directly into the base of the warts over three sessions.

Results showed that 76% of participants experienced complete disappearance of their warts, with another 18% seeing partial improvement. The treatment was not only effective but also cost-efficient, and side effects were minimal.

This findings suggest that vitamin D injections could be a promising approach for those seeking alternatives to conventional wart treatments.
Read More

Most Useful Reviews

10
Leg wart gone!
Excellent! This vitamin D works wonders. My whole family takes it, and my husband had a wart on his leg that completely disappeared after taking the vitamin.
Read More
9
Warts fell off!
This is not the first time we've ordered this D3. We take it as a family, including my retired parents. The dosage works well and the results are evident! Prior to starting, my wife's D3 level was at 12 and after three months, it rose dramatically. She noticed she began to sleep better and felt more energetic, and significantly, about five warts on her hands fell off on their own! We highly recommend this D3!
Read More
9
Effective treatment!
This is the best D3! We continually order it now in 240 capsule bottles. The dosage is excellent and the results are visible! We took tests before starting and found my wife's D3 level was 12, which tripled after three months. She also noticed better sleep and increased energy, which is great, but most importantly, five warts on her hands just fell off! We wholeheartedly recommend this D3!
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.4
  • All Researches
9.5
Topical vitamin D outperforms injection
We explored the effectiveness of two forms of vitamin D in treating cutaneous warts: a topical ointment and an intralesional injection. In a study with 56 participants, results showed the topical treatment had a higher success rate, with 95% of patients responding completely compared to 59% in the injection group.

Furthermore, the topical group experienced fewer side effects and no recurrences, while some patients in the injection group faced challenges post-treatment. Overall, topical vitamin D appears to be the more effective option for wart treatment.
Read More
9.5
Vitamin D3 effectively treats warts
We conducted a clinical trial to explore the effectiveness of intralesional vitamin D3 as a treatment for cutaneous warts. Involving 40 patients, we injected a vitamin D3 solution into the bases of their warts over several sessions.

The results were promising, with 81.9% achieving complete clearance of their warts after treatment, while only a small percentage showed no improvement. Most patients tolerated the treatment well, reporting only minor side effects.

Overall, vitamin D3 proves to be an effective and affordable option for wart treatment.
Read More
9.5
Vitamin D3 shows promise for warts
We investigated the effectiveness of vitamin D3 injections for treating anogenital warts, specifically condyloma acuminata. In a reported case, one male patient showed complete clearance of warts after this novel treatment.

Remarkably, there were no signs of recurrence during the six-month follow-up. This suggests that vitamin D3 could be a promising alternative to traditional, more cumbersome treatments that often require multiple sessions.
Read More
9
Vitamin D effectively treats warts
We aimed to evaluate the effectiveness of intralesional vitamin D injections in treating stubborn warts. Our study included 92 patients, where vitamin D was injected directly into the base of the warts over three sessions.

Results showed that 76% of participants experienced complete disappearance of their warts, with another 18% seeing partial improvement. The treatment was not only effective but also cost-efficient, and side effects were minimal.

This findings suggest that vitamin D injections could be a promising approach for those seeking alternatives to conventional wart treatments.
Read More
We investigated various treatments for plantar warts, particularly focusing on the effectiveness of intralesional vitamin D3. According to our review of 26 studies, vitamin D3 showed promise, boasting a median cure rate of 80%.

While other options like bleomycin and Candida antigen were less effective, they remain viable alternatives due to their availability. Intralesional vitamin D3 stands out as a potential first-line treatment, though it is not currently accessible in the U.S.

Additionally, we noted that the HPV vaccine deserves attention for both treating and preventing these warts.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Leg wart gone!
Excellent! This vitamin D works wonders. My whole family takes it, and my husband had a wart on his leg that completely disappeared after taking the vitamin.
Read More
9
Warts fell off!
This is not the first time we've ordered this D3. We take it as a family, including my retired parents. The dosage works well and the results are evident! Prior to starting, my wife's D3 level was at 12 and after three months, it rose dramatically. She noticed she began to sleep better and felt more energetic, and significantly, about five warts on her hands fell off on their own! We highly recommend this D3!
Read More
9
Effective treatment!
This is the best D3! We continually order it now in 240 capsule bottles. The dosage is excellent and the results are visible! We took tests before starting and found my wife's D3 level was 12, which tripled after three months. She also noticed better sleep and increased energy, which is great, but most importantly, five warts on her hands just fell off! We wholeheartedly recommend this D3!
Read More
9
Visible improvement!
Excellent vitamin! Within a week, the effects were noticeable; my skin improved and a wart that I'd struggled with in various ways vanished. The price-to-quality ratio is superb, essential for those who work indoors and only see the sun through a window.
Read More
9
No more colds!
It truly works! An excellent product! After starting treatment, a wart on my index finger disappeared on its own! My immunity improved significantly, and I haven’t had colds for the whole year. I always choose this brand of vitamin D3 and I’m thrilled with the results. Highly recommended!
Read More

Frequently Asked Questions

9
Visible improvement!
Excellent vitamin! Within a week, the effects were noticeable; my skin improved and a wart that I'd struggled with in various ways vanished. The price-to-quality ratio is superb, essential for those who work indoors and only see the sun through a window.
9
No more warts!
I recommend this for anyone! My husband, who frequently suffered from respiratory infections and constant warts, took vitamin C along with D and omega 800. A month later, we no longer worried about his warts and he got sick much less often. Consult with a doctor before purchasing.
9
Warts fell off!
This is not the first time we've ordered this D3. We take it as a family, including my retired parents. The dosage works well and the results are evident! Prior to starting, my wife's D3 level was at 12 and after three months, it rose dramatically. She noticed she began to sleep better and felt more energetic, and significantly, about five warts on her hands fell off on their own! We highly recommend this D3!
9
Effective treatment!
This is the best D3! We continually order it now in 240 capsule bottles. The dosage is excellent and the results are visible! We took tests before starting and found my wife's D3 level was 12, which tripled after three months. She also noticed better sleep and increased energy, which is great, but most importantly, five warts on her hands just fell off! We wholeheartedly recommend this D3!
10
Leg wart gone!
Excellent! This vitamin D works wonders. My whole family takes it, and my husband had a wart on his leg that completely disappeared after taking the vitamin.
9
No more colds!
It truly works! An excellent product! After starting treatment, a wart on my index finger disappeared on its own! My immunity improved significantly, and I haven’t had colds for the whole year. I always choose this brand of vitamin D3 and I’m thrilled with the results. Highly recommended!
9
Warts completely gone!
I’m not sure if it’s a miracle, but after taking it with omega, my warts disappeared. I had them on my heel and hand since childhood; now they’ve all vanished. I drink it every few days.
7.5
Wart disappeared!
3 people found this helpful
A small piece, easy to swallow. I heard that vitamin D can reduce adverse reactions to vaccines, so I bought a few bottles and took one tablet every two days. Many girls fear exposure to the sun and are prone to vitamin D deficiency, so IHerbs offers the best quality. Additionally, I had warts on my face. A dermatologist mentioned that individuals lacking vitamin D are more likely to develop warts. Naturally, sunbathing is the ideal solution, but I was concerned about sunburn, so I purchased vitamin D instead. After a while of taking it, I noticed that a wart had disappeared on its own.
9
Vitamin D effectively treats warts
We aimed to evaluate the effectiveness of intralesional vitamin D injections in treating stubborn warts. Our study included 92 patients, where vitamin D was injected directly into the base of the warts over three sessions.

Results showed that 76% of participants experienced complete disappearance of their warts, with another 18% seeing partial improvement. The treatment was not only effective but also cost-efficient, and side effects were minimal.

This findings suggest that vitamin D injections could be a promising approach for those seeking alternatives to conventional wart treatments.
9.5
Topical vitamin D outperforms injection
We explored the effectiveness of two forms of vitamin D in treating cutaneous warts: a topical ointment and an intralesional injection. In a study with 56 participants, results showed the topical treatment had a higher success rate, with 95% of patients responding completely compared to 59% in the injection group.

Furthermore, the topical group experienced fewer side effects and no recurrences, while some patients in the injection group faced challenges post-treatment. Overall, topical vitamin D appears to be the more effective option for wart treatment.
2
Vitamin D3 less effective for warts
We tested two treatments for multiple common warts: intralesional Candida antigen and vitamin D3. In a study with 80 adults, participants received injections every three weeks for up to four sessions.

While Candida antigen showed impressive results, with a 76.7% clearance rate, vitamin D3 only achieved a 20% success rate. Importantly, the side effects were minimal for both treatments. Overall, our findings indicate that Candida antigen is a more effective option compared to vitamin D3 for treating stubborn warts.
We explored the effectiveness of intralesional vitamin D3 in treating cutaneous warts compared to cryotherapy in a randomized controlled trial involving 50 patients.

Both treatments showed promise, but we found that vitamin D3 led to a significantly higher rate of complete wart resolution.

The most common warts were plantar warts, seen predominantly on the feet. Our findings suggest that vitamin D3 might be a more effective option for managing these warts.
7
Vitamin D shows limited wart efficacy
We explored the effects of vitamin D in treating skin warts through a well-structured study involving 200 patients. Participants received injections of either vitamin D, a placebo, or other vaccines into their largest wart, monitored over several sessions.

Our findings revealed that the effectiveness of vitamin D was similar to that of the placebo, with only minor side effects reported. Both treatment groups experienced comparable rates of wart clearance, indicating that vitamin D may not be the solution many hoped for in wart treatment.

References

  1. Shaafie HI, Koti VR, Saxena K, Shukla P. Intralesional immunotherapy of cutaneous warts using tuberculin purified protein derivative and vitamin D - A randomized comparative study. J Cutan Aesthet Surg. 2025;18:86. 10.25259/jcas_178_23
  2. Almuhyi RA, Alhamdi KI, Alhamdi DK. Topical Vitamin D Derivative (Calcipotriol) Versus Intralesional Vitamin D in the Treatment of Cutaneous Warts: A Clinical Therapeutic Comparative Trial. Dermatol Res Pract. 2024;2024:5236290. 10.1155/2024/5236290
  3. Aryal E, Bhari J, Shrestha PR. Immunotherapy with Intralesional Vit D injection in Recalcitrant wart at a Tertiary Care Center: A Descriptive Cross sectional Study. JNMA J Nepal Med Assoc. 2024;62:378. 10.31729/jnma.8614
  4. Cao Y, Zhou X, Yang H. Association of vitamin D with risk of warts: A retrospective and Mendelian randomization study. Skin Res Technol. 2024;30:e13911. 10.1111/srt.13911
  5. Noureen U, Shah RR, Waqas N, Sharif S, Shah A, et al. Efficacy of Intralesional Vitamin D3 for Treatment of Verruca Vulgaris: A Randomized Control Study. J Clin Aesthet Dermatol. 2023;16:47.
  6. Al-Sabak H, Al-Hattab M, Al-Rammahi M, Al-Dhalimi M. The efficacy of intralesional vitamin D3 injection in the treatment of cutaneous warts: A clinical therapeutic trial study. Skin Res Technol. 2023;29:e13442. 10.1111/srt.13442
  7. Chaudhary M, Brar A, Agarwal P, Chavda V, Jagati A, et al. A Study of Comparison and Evaluation of Various Intralesional Therapies in Cutaneous Warts. Indian Dermatol Online J. 2023;14:487. 10.4103/idoj.idoj_492_22
  8. El Sharkawy DA, Nada HR, Radman Al-Kubati S. Comparative Study Among CO 2 Laser, Intralesional Vitamin D3, and Combined Intralesional Vitamin D3 and CO 2 Laser in Treatment of Palmoplantar Warts. Dermatol Surg. 2023;49:771. 10.1097/DSS.0000000000003846
  9. Lahoria U, Singh S, Bhardwaj A, Budania A, Chhajed N, et al. A prospective randomized controlled study of Mycobacterium Indicus Pranii vaccine, Measles Mumps Rubella vaccine and Vitamin D3 in extragenital cutaneous warts. J Cosmet Dermatol. 2023;22:1400. 10.1111/jocd.15564
  10. Nasr M, Abdelaty S, Elkholy BM. A comparative clinico-dermoscopic study of intralesional injection of combined digoxin and furosemide, Candida antigen, and vitamin D3 for multiple warts. J Cosmet Dermatol. 2023;22:1344. 10.1111/jocd.15581
  11. Martin A, Thatiparthi A, Nourmohammadi N, Nguyen C, Sung C, et al. Emerging Intralesional Treatments for Plantar Warts: A Systematic Review. J Drugs Dermatol. 2022;21:1322. 10.36849/JDD.6735
  12. Singh AK, Devi KN, Bist JS. A comparative evaluation of therapeutic response in warts to intralesional vitamin D3 versus intralesional measles, mumps, and rubella vaccine. Dermatol Ther. 2022;35:e15813. 10.1111/dth.15813
  13. Zainab Z, Malik NA, Malik S, Mashhood A, Obaid S, et al. Role Of Intralesional Vitamin-D In Viral Wartse. J Ayub Med Coll Abbottabad. 2021;33:598.
  14. Abdel Razik LH, Obaid ZM, Fouda I. Intralesional Candida antigen versus intralesional vitamin D3 in the treatment of recalcitrant multiple common warts. J Cosmet Dermatol. 2021;20:3341. 10.1111/jocd.14335
  15. Abdelaal MA, Abdelaziz HM, Ahmed KA, Elsaie ML. Comparative Study of Intralesional Vitamin D3 Injection and Candida Albicans Antigen in Treating Plantar Warts. J Drugs Dermatol. 2021;20:546. 10.36849/JDD.5264
  16. Jha N. Complete clearance of condyloma acuminata using injection Vitamin D3. Australas J Dermatol. 2021;62:e417. 10.1111/ajd.13586
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