We sought to understand how doxercalciferol, a form of vitamin D2, affects bone health in aging mice, particularly in relation to osteoporosis. Through a series of experiments, we investigated its potential benefits in preventing bone loss, a common issue as animals age.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
Read More
8
Vitamin D's impact on osteoporosis
The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis.
We aimed to understand how vitamin D influences bone health and helps combat osteoporosis, a condition that weakens bones. In our study, we used various mouse models, including those that mimic a deficiency in active vitamin D. Through a range of advanced methods, we assessed how changes in vitamin D levels affected bone structure and metabolism.
The research revealed that insufficient vitamin D led to a drop in Sirt1, a gene that plays a crucial role in maintaining bone density. This lack of Sirt1 resulted in increased bone loss. However, when we boosted Sirt1 levels in bone stem cells, we observed a reversal in bone loss. This improvement happened because higher Sirt1 levels reduced oxidative stress, slowed down aging processes in bone cells, and enhanced new bone formation while curbing bone resorption.
Additionally, our findings indicated that vitamin D directly stimulates Sirt1 expression in these stem cells, which is vital for bone health. We also explored the effects of resveratrol, a natural compound known for activating Sirt1, and found it helped alleviate osteoporosis symptoms linked to vitamin D deficiency by enhancing the relationship between Sirt1 and another protein called PGC1α, which supports bone formation and energy metabolism.
This research underscores the importance of the vitamin D-Sirt1/PGC1α axis in bone metabolism, providing insight into how vitamin D can serve as a target for osteoporosis prevention and treatment.
Read More
7
Vitamin D and osteoporosis insight
Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO.
We explored the effects of vitamin D supplementation on osteoporosis, especially among individuals at risk for this condition. The Osteoporosis Research and Information Group (GRIO) highlighted the critical difference between daily and intermittent vitamin D dosing.
Current literature indicates that taking high doses of vitamin D intermittently, such as 60,000 IU a month, can actually elevate the chances of falls, fractures, and even premature death in some groups. Conversely, daily supplementation of 800-1000 IU, particularly alongside calcium, has been shown to reduce falls and non-vertebral fractures in the elderly who have a vitamin D deficiency.
Before anyone starts supplementing, it is crucial to measure their vitamin D levels to achieve a target concentration of 30 to 60 ng/mL. For those needing a quick boost in vitamin D levels—like patients showing symptoms of osteomalacia or those with critically low vitamin D—a starting loading dose followed by daily maintenance is the preferred approach. If daily options aren’t available, of course, a smaller intermittent dose can be a temporary solution until better options are accessible.
Read More
Most Useful Reviews
9
Effective alternative found
12 people found this helpful
Much better and less hazardous than taking Fosamax! My husband takes this for his osteoporosis, and it works well. He switched from Fosamax due to side effects to a more natural method, which has proven successful without side effects.
Read More
9
Helps manage osteoporosis
Excellent! This product is crucial for me due to osteoporosis. Following my doctor's recommendation, it has been beneficial.
Read More
9
Improves mood
I had low vitamin D levels during a check-up and began taking this after an injection. Vitamin D deficiency can lead to osteoporosis, and I've found that taking just one tablet daily has helped lift my spirits.
We explored how a specific probiotic strain, FSHHK13M1, affects vitamin D metabolism and osteoporosis in mice. Previous research pointed out that the gut microbiota plays a crucial role in vitamin D metabolism, which is especially relevant for older adults who tend to suffer from osteoporosis due to declining organ functions.
Our study demonstrated that treating the mice with FSHHK13M1 led to a significant increase in their serum levels of active vitamin D metabolites, particularly 1,25-dihydroxy vitamin D. This increase was linked to activation of important bone health pathways, helping to fortify bone structure and function.
Not only did we observe improvements in vitamin D levels, but the intervention also restored balance in the gut microbiota, which showed signs of imbalance in mice suffering from osteoporosis. The findings suggest that FSHHK13M1 could be a promising direction for improving bone health and reducing fracture risks in the elderly by enhancing vitamin D levels naturally.
Overall, this research highlights the potential of combining probiotics with vitamin D strategies for better management of osteoporosis, especially in older populations who often face challenges absorbing conventional treatments.
Read More
9
Doxercalciferol improves bone health
Doxercalciferol Alleviates Bone Deteriorations and Cartilage Degeneration in Aging Mice.
We sought to understand how doxercalciferol, a form of vitamin D2, affects bone health in aging mice, particularly in relation to osteoporosis. Through a series of experiments, we investigated its potential benefits in preventing bone loss, a common issue as animals age.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
Read More
9
Bone health product improves BMD
Combination of micellar casein with calcium and vitamins D2 and K2 improves bone status of ovariectomized mice.
We explored the potential benefits of a unique bone health product that combines micellar casein with calcium, vitamin D2, and vitamin K2, specifically for improving bone mineral density (BMD). Using ovariectomized mice, a model that closely resembles postmenopausal osteoporosis in humans, we assessed how different concentrations of this product affected bone quality over time.
Our findings highlighted that when administered consistently, this innovative bone health product effectively improved BMD in the mice. While vitamin D2 was one of the crucial ingredients, its isolated effect on the outcomes was difficult to determine since it was part of a combination formulation. However, the overall results supported the idea that incorporating calcium and these vitamins can be an effective approach to enhance bone health.
This study underscores the importance of nutrition in addressing bone-related issues, showing that a well-formulated product can aid in maintaining bone density and quality, especially in scenarios akin to osteoporosis. Although more research is essential to isolate the effects of each component, the positive results here are promising for future nutritional strategies aimed at osteoporosis management.
Read More
9
Vitamin D2 aids osteoporosis management
Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis.
We examined the impact of vitamin D supplementation on bone health in Korean postmenopausal women suffering from osteoporosis. Our research involved a screening phase for a broader study on a medication called denosumab, where we collected data specifically on vitamin D levels.
In our study, we focused on women aged 60 to 90 years who had serum vitamin D levels below 50 nmol/L, the point considered deficient. Those participants received a supplement of 1000 IU of vitamin D daily over a screening period of 2.5 months. We utilized advanced methods to measure both vitamin D2 and D3 levels in their blood.
Out of 371 women screened, a remarkable 191 were found to need vitamin D supplementation, and 88% of these individuals successfully reached the recommended vitamin D level. Notably, more than half of those who improved had been taking higher doses of 2000 IU daily. This repletion was achieved in an average of just 31 days, showcasing an effective turnaround.
This study highlights the significant role that vitamin D supplementation can play in managing osteoporosis among postmenopausal women in Korea. With the vast majority showing positive results, it’s clear that proper vitamin D intake is crucial for bone health in this population.
Read More
8
Vitamin D aids cancer treatment outcomes
A Systematic Review of Vitamin D Supplementation in Oncology: Chance of Science or Effectiveness?
We explored the role of vitamin D (VD) supplementation in supporting cancer patients undergoing chemotherapy and radiotherapy, particularly regarding its effects on osteoporosis. The aim was to sift through scientific evidence to understand how vitamin D influences not just bone health but also alleviates the side effects of demanding cancer treatments.
Our findings indicated that adequate levels of VD are important for maintaining bone density in patients, especially those receiving preoperative chemoradiotherapy. Some studies showed that vitamin D supplementation could lessen certain severe side effects, like fatigue and nausea, often experienced during cancer treatments.
However, the evidence regarding the isolated effects of vitamin D on osteoporosis, specifically, was limited due to the varied designs of the included studies. Despite these challenges, it seems clear that vitamin D plays a valuable role in managing bone health and reducing treatment-related complications.
Much better and less hazardous than taking Fosamax! My husband takes this for his osteoporosis, and it works well. He switched from Fosamax due to side effects to a more natural method, which has proven successful without side effects.
Read More
9
Helps manage osteoporosis
Excellent! This product is crucial for me due to osteoporosis. Following my doctor's recommendation, it has been beneficial.
Read More
9
Improves mood
I had low vitamin D levels during a check-up and began taking this after an injection. Vitamin D deficiency can lead to osteoporosis, and I've found that taking just one tablet daily has helped lift my spirits.
Read More
7.5
Supports bone health
Ergocalciferol aids in the absorption of calcium and phosphorus, which is vital for maintaining healthy bones and teeth. It helps prevent the development of osteoporosis and rickets.
Read More
7.5
Strengthens bones
Ergocalciferol enhances calcium and phosphorus absorption, which strengthens bones and teeth. It supports the immune system, reduces infection risks, and plays a role in muscle and nervous system function. It may help in osteoporosis prevention and overall well-being.
Osteoporosis is a medical condition characterized by weakened bones, making them fragile and more prone to fractures. This condition occurs when the body loses too much bone mass, doesn't make enough bone, or a combination of both. As bones lose density, they can break more easily, often as a result of minor falls or injury. Osteoporosis is often referred to as a "silent disease" because bone loss occurs without any symptoms until a fracture occurs, often in the hip, spine, or wrist.
Risk factors for developing osteoporosis include age, gender (it’s more common in women), family history, low body weight, and certain medical conditions and medications. Lifestyle choices such as smoking, excessive alcohol consumption, and a diet low in calcium and vitamin D can also contribute to bone loss. Regular weight-bearing exercise, ensuring adequate nutrition, and, in some cases, medications can help prevent or manage osteoporosis. If you believe you may be at risk, it is important to consult with a healthcare professional for appropriate screening and intervention options.
Vitamin D is a fat-soluble vitamin that's essential for maintaining healthy bones and teeth, supporting immune system function, and facilitating normal cell growth and development. It plays a crucial role in calcium absorption in the gut, which is vital for bone health. Unlike most vitamins, our bodies can produce Vitamin D when exposed to sunlight, specifically UVB rays, which is why it’s often referred to as the "sunshine vitamin." However, depending on your geographical location, lifestyle, and skin type, getting sufficient Vitamin D from the sun alone can be challenging, particularly during the winter months.
In addition to sunlight, Vitamin D can be obtained from certain foods such as fatty fish (like salmon and mackerel), fish liver oils, and fortified foods like milk and cereals. Some individuals may also consider supplements, especially if they're at risk for deficiency. Insufficient vitamin D levels are linked to various health issues, including rickets in children, osteomalacia in adults, and even an increased risk of chronic diseases. Regularly checking your vitamin D levels and consulting with a healthcare professional can help ensure you're meeting your needs for optimal health.
Vitamin D plays a crucial role in bone health, and its connection to osteoporosis is well-documented. Osteoporosis is a condition characterized by weak and brittle bones, making individuals more susceptible to fractures. Adequate levels of vitamin D are essential for the body to absorb calcium, which is vital for maintaining bone density and strength. When vitamin D levels are low, the body cannot effectively use calcium, potentially leading to a decrease in bone mass and an increased risk of osteoporosis.
Several studies have shown that vitamin D supplementation can have a positive impact on bone health, particularly in older adults who are more prone to osteoporosis. While vitamin D alone is not a standalone treatment for osteoporosis, it is typically recommended alongside calcium and other lifestyle changes, such as weight-bearing exercise, to help mitigate the risk of bone loss. If you are concerned about osteoporosis or your vitamin D levels, it’s advisable to consult with a healthcare professional who can provide personalized recommendations based on your specific needs and health status.
Based on user reviews, the timeline for seeing results from taking this supplement for osteoporosis appears to vary. While specific timeframes are not explicitly mentioned, several users have indicated noticeable benefits after starting their regimen. One user mentioned that after taking the supplement post-injection for low vitamin D, they felt an uplift in their spirits and wellness, which suggests some immediate positive effects could be experienced soon after starting (Read Review). Another user shared that they continued to use the supplement to prevent osteoporosis effectively, hinting at ongoing benefits that support long-term health (Read Review).
Overall, while individual experiences may differ, users report that noticeable improvements can occur fairly quickly, likely within weeks, especially when combined with a comprehensive health and dietary plan. It’s also emphasized that continued consumption is important for ongoing bone health support and deficiency prevention.
The scientific research suggests that vitamin D supplementation plays a significant role in the management of osteoporosis. Various studies have indicated that adequate vitamin D levels are crucial for maintaining bone density, especially in individuals at risk of osteoporosis, such as older adults and postmenopausal women. For instance, a study found that daily supplementation of 800-1000 IU of vitamin D combined with calcium reduced the risk of falls and non-vertebral fractures among the elderly who were vitamin D deficient [4]. Moreover, another investigation demonstrated that insufficient vitamin D levels were an independent risk factor for new osteoporotic vertebral fractures in postmenopausal women [6].
However, the isolated effects of vitamin D on osteoporosis may vary, and the evidence surrounding its efficacy is complex due to factors such as the individual's vitamin D baseline levels and the method of supplementation. Notably, vitamin D2 appears to be less effective than vitamin D3 in enhancing bone health, with recent studies showing significant advantages of D3 in increasing vitamin D status [15]. Hence, while there is considerable support within the scientific community for the benefits of vitamin D in osteoporosis management, the type of vitamin D and its dosage are essential aspects that should be tailored to individual needs for optimal outcomes.
Based on user reviews, many individuals have reported significant improvements in their symptoms after using the vitamin D supplement, particularly in relation to osteoporosis management. One user noted that following their doctor's recommendation, the product was crucial for their condition, indicating its importance in their health regimen (Read Review). Another user shared that after addressing a vitamin D deficiency, they experienced a lift in their spirits and overall wellness, suggesting psychological benefits alongside physical improvements, which is especially relevant to those concerned about osteoporosis (Read Review).
Additionally, users highlighted the role of ergocalciferol in enhancing calcium and phosphorus absorption, crucial for maintaining bone health and preventing osteoporosis. Feedback indicated that regular supplementation not only supports bone density but also positively impacts the immune system and reduces infection risks (Read Review). Overall, while individual results can vary, many reviews reflect a consensus that this supplement may contribute to improved bone health and well-being, especially when used continuously.Read Review
Users have reported positive experiences when combining this supplement with other vitamins or minerals to manage osteoporosis. Many reviews highlight the synergistic role of vitamin D, especially ergocalciferol, in enhancing calcium and phosphorus absorption, which are crucial for bone health (Read Review, Read Review). Several users noted that taking vitamin D has contributed to the overall effectiveness of their osteoporosis prevention strategies, confirming that it plays a crucial role within a well-rounded supplement regimen or as part of a doctor's recommendation (Read Review, Read Review).
Moreover, users indicated that regular intake of this vitamin leads to an improvement not only in bone density but also in overall wellness. One user specifically mentioned that the supplement was pivotal in lifting their spirits after addressing a vitamin D deficiency, suggesting benefits that extend beyond just physical health Read Review. For those looking to maximize the benefits of their osteoporosis management, incorporating this supplement with a targeted approach to diet and additional nutrients appears to be highly recommended by user feedback (Read Review).
The optimal dose of Vitamin D for treating osteoporosis typically falls within the range of 800 to 1000 IU daily. This dosage has been shown to effectively reduce falls and non-vertebral fractures, particularly in elderly individuals who are vitamin D deficient [4]. It's critical to measure vitamin D levels to ensure concentrations reach a target range of about 30 to 60 ng/mL before starting supplementation [4].
For patients requiring immediate normalization of low vitamin D levels, a loading dose followed by the recommended daily maintenance is advisable. If daily supplementation is not feasible, smaller intermittent doses can provide a temporary solution [4]. Additionally, for specific populations, such as postmenopausal women, higher doses up to 2000 IU may be more effective in achieving necessary serum levels and improving bone density outcomes [16].
9
Improves mood
I had low vitamin D levels during a check-up and began taking this after an injection. Vitamin D deficiency can lead to osteoporosis, and I've found that taking just one tablet daily has helped lift my spirits.
7.5
Prevents osteoporosis
I repurchased this product for use outside of winter. It seems effective in preventing osteoporosis and compensating for deficiencies.
9
Helps manage osteoporosis
Excellent! This product is crucial for me due to osteoporosis. Following my doctor's recommendation, it has been beneficial.
7.5
Strengthens bones
Ergocalciferol enhances calcium and phosphorus absorption, which strengthens bones and teeth. It supports the immune system, reduces infection risks, and plays a role in muscle and nervous system function. It may help in osteoporosis prevention and overall well-being.
7.5
Supports bone health
Ergocalciferol aids in the absorption of calcium and phosphorus, which is vital for maintaining healthy bones and teeth. It helps prevent the development of osteoporosis and rickets.
7.5
Boosts immunity
High quality with clean ingredients, free from genetic modification. It raises vitamin D levels, strengthens immunity, and treats osteoporosis.
7
Vitamin D and osteoporosis insight
Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO.
We explored the effects of vitamin D supplementation on osteoporosis, especially among individuals at risk for this condition. The Osteoporosis Research and Information Group (GRIO) highlighted the critical difference between daily and intermittent vitamin D dosing.
Current literature indicates that taking high doses of vitamin D intermittently, such as 60,000 IU a month, can actually elevate the chances of falls, fractures, and even premature death in some groups. Conversely, daily supplementation of 800-1000 IU, particularly alongside calcium, has been shown to reduce falls and non-vertebral fractures in the elderly who have a vitamin D deficiency.
Before anyone starts supplementing, it is crucial to measure their vitamin D levels to achieve a target concentration of 30 to 60 ng/mL. For those needing a quick boost in vitamin D levels—like patients showing symptoms of osteomalacia or those with critically low vitamin D—a starting loading dose followed by daily maintenance is the preferred approach. If daily options aren’t available, of course, a smaller intermittent dose can be a temporary solution until better options are accessible.
8
Vitamin D's role in fracture risk
Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study.
We examined the relationship between vitamin D levels and the risk of new vertebral fractures after patients underwent a specific spine procedure called percutaneous vertebral augmentation. Our focus was on postmenopausal women aged 50 and above, who often face an increased risk of fractures due to osteoporosis.
In this retrospective study, we categorized patients into groups based on whether they experienced new osteoporotic vertebral fractures or not. Our analysis revealed that low levels of serum 25-hydroxyvitamin D are an independent risk factor for these new fractures.
This suggests that maintaining adequate vitamin D levels could be crucial for individuals recovering from this type of spinal surgery. By ensuring active vitamin D supplementation after the procedure, patients may significantly lower their chances of future osteoporotic vertebral fractures, promoting better recovery and overall health.
8
Vitamin D3 outperforms D2
Effects of High-Dose Vitamin D2 Versus D3 on Total and Free 25-Hydroxyvitamin D and Markers of Calcium Balance.
We evaluated how vitamin D2 compares to vitamin D3 in restoring low levels of 25-hydroxyvitamin D (25D), a key indicator of vitamin D status, particularly in adults with osteoporosis. Our focus was on understanding whether vitamin D2 effectively supports calcium balance and overall vitamin D bioactivity compared to its counterpart, D3.
In a carefully designed study, participants with low baseline 25D levels received high doses of either vitamin D2 or D3 over ten weeks. We observed that while both forms were introduced with equal levels of intake, the results revealed a notable advantage for vitamin D3. Specifically, D3 significantly increased both total and free 25D levels compared to D2, indicating its superior ability to enhance vitamin D status.
Importantly, we found that changes in the intact parathyroid hormone (iPTH) were more closely linked to changes in free 25D levels than total 25D, thereby suggesting that free 25D may be a better marker of vitamin D's bioactive effects. This insight is crucial as it highlights the potential limitations of D2 in osteoporosis management, leading us to conclude that while D2 is a valid option, D3 appears to be more effective in improving vitamin D levels, thereby potentially benefiting bone health.
9
Vitamin D2 aids osteoporosis management
Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis.
We examined the impact of vitamin D supplementation on bone health in Korean postmenopausal women suffering from osteoporosis. Our research involved a screening phase for a broader study on a medication called denosumab, where we collected data specifically on vitamin D levels.
In our study, we focused on women aged 60 to 90 years who had serum vitamin D levels below 50 nmol/L, the point considered deficient. Those participants received a supplement of 1000 IU of vitamin D daily over a screening period of 2.5 months. We utilized advanced methods to measure both vitamin D2 and D3 levels in their blood.
Out of 371 women screened, a remarkable 191 were found to need vitamin D supplementation, and 88% of these individuals successfully reached the recommended vitamin D level. Notably, more than half of those who improved had been taking higher doses of 2000 IU daily. This repletion was achieved in an average of just 31 days, showcasing an effective turnaround.
This study highlights the significant role that vitamin D supplementation can play in managing osteoporosis among postmenopausal women in Korea. With the vast majority showing positive results, it’s clear that proper vitamin D intake is crucial for bone health in this population.
References
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Wang H, Tian G, Pei Z, Yu X, Wang Y, et al. increases serum vitamin D metabolite levels and modulates intestinal flora to alleviate osteoporosis in mice. mSphere. 2025. doi:10.1128/msphere.01039-24
Skubica P, Hoffmanova I, Dankova P. Chronically increased osteoclastogenesis in adult celiac disease patients does not hinder improvement in bone health induced by gluten-free diet: Role of vitamin D, OPG and IL-6. J Nutr Biochem. 2025. doi:10.1016/j.jnutbio.2025.109871
Pickering ME, Souberbielle JC, Boutten A, Breuil V, Briot K, et al. Daily or intermittent vitamin D supplementation in patients with or at risk of osteoporosis: Position statement from the GRIO. Joint Bone Spine. 2025;92:105858. doi:10.1016/j.jbspin.2025.105858
Shi L, Bao Y, Deng X, Xu X, Hu J. Association between calcium and vitamin D supplementation and increased risk of kidney stone formation in patients with osteoporosis in Southwest China: a cross-sectional study. BMJ Open. 2025;15:e092901. doi:10.1136/bmjopen-2024-092901
Zhang SB, Yang J, Xu HW, Yi YY, Ren CX, et al. Association Between 25-hydroxyvitamin D Status and New Vertebral Fractures Post Percutaneous Vertebral Augmentation in Patients During Postmenopause: A Retrospective Case-control Study. Pain Physician. 2025;28:E31.
Yang C, Chen L, Guo X, Sun H, Miao D. The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis. J Orthop Translat. 2025;50:211. doi:10.1016/j.jot.2024.10.011
Kuwabara N, Kanda J, Sato S, Nakagawa S. Impact of Daily High Ergosterol Intake for 14 Weeks in Ovariectomized Rats on Cholesterol and Vitamin D Biosynthesis Pathways. Biol Pharm Bull. 2025;48:39. doi:10.1248/bpb.b24-00536
McCarrison S, Abdelrahman S, Quinlivan R, Keen R, Wong SC. Pharmacological and non-pharmacological therapies for prevention and treatment of osteoporosis in Duchenne Muscular Dystrophy: A systematic review. Bone. 2025;193:117410. doi:10.1016/j.bone.2025.117410
Ma M, Zhang Y, Liu J, Tian C, Duan Z, et al. Associations of the serum 25-hydroxyvitamin D with mortality among patients in osteopenia or osteoporosis. Bone. 2025. doi:10.1016/j.bone.2025.117408
Chen Y, Sun X, Sui X, Li Y, Wang Z. Application of bone alkaline phosphatase and 25-oxhydryl-vitamin D in diagnosis and prediction of osteoporotic vertebral compression fractures. J Orthop Surg Res. 2023;18:739. doi:10.1186/s13018-023-04144-2
Li J, Li N, Yan S, Liu M, Sun B, et al. Doxercalciferol Alleviates Bone Deteriorations and Cartilage Degeneration in Aging Mice. Exp Clin Endocrinol Diabetes. 2020;128:540. doi:10.1055/a-0754-1956
Cavalier E, Lukas P, Bekaert AC, Carlisi A, Le Goff C, et al. Analytical and clinical validation of the new Abbot Architect 25(OH)D assay: fit for purpose?. Clin Chem Lab Med. 2017;55:378. doi:10.1515/cclm-2016-0566
Boulier A, Schwarz J, Lespesailles E, Baniel A, Tomé D, et al. Combination of micellar casein with calcium and vitamins D2 and K2 improves bone status of ovariectomized mice. Osteoporos Int. 2016;27:3103. doi:10.1007/s00198-016-3638-z
Shieh A, Chun RF, Ma C, Witzel S, Meyer B, et al. Effects of High-Dose Vitamin D2 Versus D3 on Total and Free 25-Hydroxyvitamin D and Markers of Calcium Balance. J Clin Endocrinol Metab. 2016;101:3070. doi:10.1210/jc.2016-1871
Chung YS, Chung DJ, Kang MI, Kim IJ, Koh JM, et al. Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis. Yonsei Med J. 2016;57:923. doi:10.3349/ymj.2016.57.4.923