' 
SCIENTIFIC SCORE
Most Likely Effective
Based on 6 Researches
8.3
USERS' SCORE
Very Good
Based on 7 Reviews
8.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Vitamin D2 (as Ergocalciferol)
25 mcg (1,000 IU)
125%
Top Medical Research Studies
9
Doxercalciferol improves bone health
Doxercalciferol Alleviates Bone Deteriorations and Cartilage Degeneration in Aging Mice.
Directly addresses osteoporosis treatment
We sought to understand how doxercalciferol, a form of vitamin D2, affects bone health in aging mice, particularly in relation to osteoporosis. Through a series of experiments, we investigated its potential benefits in preventing bone loss, a common issue as animals age.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
Read More
8
Vitamin D2 improves osteoporosis management
Application of bone alkaline phosphatase and 25-oxhydryl-vitamin D in diagnosis and prediction of osteoporotic vertebral compression fractures.
Focused on vitamin D2's effects
We explored the impact of vitamin D2 treatment on patients suffering from osteoporotic vertebral compression fractures (OVCFs). In this study, we included 110 patients who underwent a procedure called percutaneous vertebroplasty. We also looked at a control group receiving standard postoperative care and another group that received vitamin D2 injections after surgery.
Throughout the study, we noticed that bone alkaline phosphatase (B-ALP) levels rose while 25-oxhydryl-vitamin D (25-OH-VD) levels dropped in patients with OVCFs. Importantly, our findings suggest that we can effectively use B-ALP and 25-OH-VD to predict and diagnose these types of fractures. Furthermore, our results indicate that injecting vitamin D2 intramuscularly can enhance treatment outcomes and improve the quality of life for these patients.
Overall, this study highlights the potential benefits of vitamin D2 in managing osteoporosis and provides evidence for its role in helping patients recover from fractures more effectively.
Throughout the study, we noticed that bone alkaline phosphatase (B-ALP) levels rose while 25-oxhydryl-vitamin D (25-OH-VD) levels dropped in patients with OVCFs. Importantly, our findings suggest that we can effectively use B-ALP and 25-OH-VD to predict and diagnose these types of fractures. Furthermore, our results indicate that injecting vitamin D2 intramuscularly can enhance treatment outcomes and improve the quality of life for these patients.
Overall, this study highlights the potential benefits of vitamin D2 in managing osteoporosis and provides evidence for its role in helping patients recover from fractures more effectively.
Read More
9
Vitamin D2 aids osteoporosis management
Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis.
Focus on vitamin D2 impact
We examined the impact of vitamin D supplementation on bone health in Korean postmenopausal women suffering from osteoporosis. Our research involved a screening phase for a broader study on a medication called denosumab, where we collected data specifically on vitamin D levels.
In our study, we focused on women aged 60 to 90 years who had serum vitamin D levels below 50 nmol/L, the point considered deficient. Those participants received a supplement of 1000 IU of vitamin D daily over a screening period of 2.5 months. We utilized advanced methods to measure both vitamin D2 and D3 levels in their blood.
Out of 371 women screened, a remarkable 191 were found to need vitamin D supplementation, and 88% of these individuals successfully reached the recommended vitamin D level. Notably, more than half of those who improved had been taking higher doses of 2000 IU daily. This repletion was achieved in an average of just 31 days, showcasing an effective turnaround.
This study highlights the significant role that vitamin D supplementation can play in managing osteoporosis among postmenopausal women in Korea. With the vast majority showing positive results, it’s clear that proper vitamin D intake is crucial for bone health in this population.
In our study, we focused on women aged 60 to 90 years who had serum vitamin D levels below 50 nmol/L, the point considered deficient. Those participants received a supplement of 1000 IU of vitamin D daily over a screening period of 2.5 months. We utilized advanced methods to measure both vitamin D2 and D3 levels in their blood.
Out of 371 women screened, a remarkable 191 were found to need vitamin D supplementation, and 88% of these individuals successfully reached the recommended vitamin D level. Notably, more than half of those who improved had been taking higher doses of 2000 IU daily. This repletion was achieved in an average of just 31 days, showcasing an effective turnaround.
This study highlights the significant role that vitamin D supplementation can play in managing osteoporosis among postmenopausal women in Korea. With the vast majority showing positive results, it’s clear that proper vitamin D intake is crucial for bone health in this population.
Read More
Most Useful Reviews
9.5
Helps manage osteoporosis
Excellent! This product is crucial for me due to osteoporosis. Following my doctor's recommendation, it has been beneficial.
Read More
9.5
Improves mood
I had low vitamin D levels during a check-up and began taking this after an injection. Vitamin D deficiency can lead to osteoporosis, and I've found that taking just one tablet daily has helped lift my spirits.
Read More
8.8
Supports bone health
Ergocalciferol aids in the absorption of calcium and phosphorus, which is vital for maintaining healthy bones and teeth. It helps prevent the development of osteoporosis and rickets.
Read More
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Medical Researches
SCIENTIFIC SCORE
Most Likely Effective
Based on 6 Researches
8.3
9
Doxercalciferol improves bone health
Doxercalciferol Alleviates Bone Deteriorations and Cartilage Degeneration in Aging Mice.
Directly addresses osteoporosis treatment
We sought to understand how doxercalciferol, a form of vitamin D2, affects bone health in aging mice, particularly in relation to osteoporosis. Through a series of experiments, we investigated its potential benefits in preventing bone loss, a common issue as animals age.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
Our findings revealed that aging mice exhibited increased urine calcium excretion, decreased bone calcium content, and a reduction in biomechanical strength. However, upon administering doxercalciferol, we observed significant effects; especially, it lowered serum parathyroid hormone (PTH) levels which are commonly elevated in aging.
Additionally, our analysis through specific staining techniques confirmed that doxercalciferol helped protect against bone loss and supported cartilage regeneration. We also noted that the treatment enhanced the activity of bone-building cells while inhibiting the activity of cells that break down bone.
Overall, these results suggest that doxercalciferol could be an effective treatment for aging-related osteoporosis by enhancing bone health and improving overall quality of life.
Read More
9
Bone health product improves BMD
Combination of micellar casein with calcium and vitamins D2 and K2 improves bone status of ovariectomized mice.
Moderate relevance regarding vitamin D2
We explored the potential benefits of a unique bone health product that combines micellar casein with calcium, vitamin D2, and vitamin K2, specifically for improving bone mineral density (BMD). Using ovariectomized mice, a model that closely resembles postmenopausal osteoporosis in humans, we assessed how different concentrations of this product affected bone quality over time.
Our findings highlighted that when administered consistently, this innovative bone health product effectively improved BMD in the mice. While vitamin D2 was one of the crucial ingredients, its isolated effect on the outcomes was difficult to determine since it was part of a combination formulation. However, the overall results supported the idea that incorporating calcium and these vitamins can be an effective approach to enhance bone health.
This study underscores the importance of nutrition in addressing bone-related issues, showing that a well-formulated product can aid in maintaining bone density and quality, especially in scenarios akin to osteoporosis. Although more research is essential to isolate the effects of each component, the positive results here are promising for future nutritional strategies aimed at osteoporosis management.
Our findings highlighted that when administered consistently, this innovative bone health product effectively improved BMD in the mice. While vitamin D2 was one of the crucial ingredients, its isolated effect on the outcomes was difficult to determine since it was part of a combination formulation. However, the overall results supported the idea that incorporating calcium and these vitamins can be an effective approach to enhance bone health.
This study underscores the importance of nutrition in addressing bone-related issues, showing that a well-formulated product can aid in maintaining bone density and quality, especially in scenarios akin to osteoporosis. Although more research is essential to isolate the effects of each component, the positive results here are promising for future nutritional strategies aimed at osteoporosis management.
Read More
9
Vitamin D2 aids osteoporosis management
Vitamin D Repletion in Korean Postmenopausal Women with Osteoporosis.
Focus on vitamin D2 impact
We examined the impact of vitamin D supplementation on bone health in Korean postmenopausal women suffering from osteoporosis. Our research involved a screening phase for a broader study on a medication called denosumab, where we collected data specifically on vitamin D levels.
In our study, we focused on women aged 60 to 90 years who had serum vitamin D levels below 50 nmol/L, the point considered deficient. Those participants received a supplement of 1000 IU of vitamin D daily over a screening period of 2.5 months. We utilized advanced methods to measure both vitamin D2 and D3 levels in their blood.
Out of 371 women screened, a remarkable 191 were found to need vitamin D supplementation, and 88% of these individuals successfully reached the recommended vitamin D level. Notably, more than half of those who improved had been taking higher doses of 2000 IU daily. This repletion was achieved in an average of just 31 days, showcasing an effective turnaround.
This study highlights the significant role that vitamin D supplementation can play in managing osteoporosis among postmenopausal women in Korea. With the vast majority showing positive results, it’s clear that proper vitamin D intake is crucial for bone health in this population.
In our study, we focused on women aged 60 to 90 years who had serum vitamin D levels below 50 nmol/L, the point considered deficient. Those participants received a supplement of 1000 IU of vitamin D daily over a screening period of 2.5 months. We utilized advanced methods to measure both vitamin D2 and D3 levels in their blood.
Out of 371 women screened, a remarkable 191 were found to need vitamin D supplementation, and 88% of these individuals successfully reached the recommended vitamin D level. Notably, more than half of those who improved had been taking higher doses of 2000 IU daily. This repletion was achieved in an average of just 31 days, showcasing an effective turnaround.
This study highlights the significant role that vitamin D supplementation can play in managing osteoporosis among postmenopausal women in Korea. With the vast majority showing positive results, it’s clear that proper vitamin D intake is crucial for bone health in this population.
Read More
8
Vitamin D2 improves osteoporosis management
Application of bone alkaline phosphatase and 25-oxhydryl-vitamin D in diagnosis and prediction of osteoporotic vertebral compression fractures.
Focused on vitamin D2's effects
We explored the impact of vitamin D2 treatment on patients suffering from osteoporotic vertebral compression fractures (OVCFs). In this study, we included 110 patients who underwent a procedure called percutaneous vertebroplasty. We also looked at a control group receiving standard postoperative care and another group that received vitamin D2 injections after surgery.
Throughout the study, we noticed that bone alkaline phosphatase (B-ALP) levels rose while 25-oxhydryl-vitamin D (25-OH-VD) levels dropped in patients with OVCFs. Importantly, our findings suggest that we can effectively use B-ALP and 25-OH-VD to predict and diagnose these types of fractures. Furthermore, our results indicate that injecting vitamin D2 intramuscularly can enhance treatment outcomes and improve the quality of life for these patients.
Overall, this study highlights the potential benefits of vitamin D2 in managing osteoporosis and provides evidence for its role in helping patients recover from fractures more effectively.
Throughout the study, we noticed that bone alkaline phosphatase (B-ALP) levels rose while 25-oxhydryl-vitamin D (25-OH-VD) levels dropped in patients with OVCFs. Importantly, our findings suggest that we can effectively use B-ALP and 25-OH-VD to predict and diagnose these types of fractures. Furthermore, our results indicate that injecting vitamin D2 intramuscularly can enhance treatment outcomes and improve the quality of life for these patients.
Overall, this study highlights the potential benefits of vitamin D2 in managing osteoporosis and provides evidence for its role in helping patients recover from fractures more effectively.
Read More
8
Vitamin D3 outperforms D2
Effects of High-Dose Vitamin D2 Versus D3 on Total and Free 25-Hydroxyvitamin D and Markers of Calcium Balance.
Limited focus on D2's effectiveness
We evaluated how vitamin D2 compares to vitamin D3 in restoring low levels of 25-hydroxyvitamin D (25D), a key indicator of vitamin D status, particularly in adults with osteoporosis. Our focus was on understanding whether vitamin D2 effectively supports calcium balance and overall vitamin D bioactivity compared to its counterpart, D3.
In a carefully designed study, participants with low baseline 25D levels received high doses of either vitamin D2 or D3 over ten weeks. We observed that while both forms were introduced with equal levels of intake, the results revealed a notable advantage for vitamin D3. Specifically, D3 significantly increased both total and free 25D levels compared to D2, indicating its superior ability to enhance vitamin D status.
Importantly, we found that changes in the intact parathyroid hormone (iPTH) were more closely linked to changes in free 25D levels than total 25D, thereby suggesting that free 25D may be a better marker of vitamin D's bioactive effects. This insight is crucial as it highlights the potential limitations of D2 in osteoporosis management, leading us to conclude that while D2 is a valid option, D3 appears to be more effective in improving vitamin D levels, thereby potentially benefiting bone health.
In a carefully designed study, participants with low baseline 25D levels received high doses of either vitamin D2 or D3 over ten weeks. We observed that while both forms were introduced with equal levels of intake, the results revealed a notable advantage for vitamin D3. Specifically, D3 significantly increased both total and free 25D levels compared to D2, indicating its superior ability to enhance vitamin D status.
Importantly, we found that changes in the intact parathyroid hormone (iPTH) were more closely linked to changes in free 25D levels than total 25D, thereby suggesting that free 25D may be a better marker of vitamin D's bioactive effects. This insight is crucial as it highlights the potential limitations of D2 in osteoporosis management, leading us to conclude that while D2 is a valid option, D3 appears to be more effective in improving vitamin D levels, thereby potentially benefiting bone health.
Read More
User Reviews
USERS' SCORE
Very Good
Based on 7 Reviews
8.8
9.5
Helps manage osteoporosis
Excellent! This product is crucial for me due to osteoporosis. Following my doctor's recommendation, it has been beneficial.
9.5
Improves mood
I had low vitamin D levels during a check-up and began taking this after an injection. Vitamin D deficiency can lead to osteoporosis, and I've found that taking just one tablet daily has helped lift my spirits.
8.8
Supports bone health
Ergocalciferol aids in the absorption of calcium and phosphorus, which is vital for maintaining healthy bones and teeth. It helps prevent the development of osteoporosis and rickets.
8.8
Strengthens bones
Ergocalciferol enhances calcium and phosphorus absorption, which strengthens bones and teeth. It supports the immune system, reduces infection risks, and plays a role in muscle and nervous system function. It may help in osteoporosis prevention and overall well-being.
8.8
Boosts immunity
High quality with clean ingredients, free from genetic modification. It raises vitamin D levels, strengthens immunity, and treats osteoporosis.
