Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Moderately Good
Based on 166 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Zinc (elemental) (from 271 mg Zinc Picolinate)
50 mg
455%

Top Medical Research Studies

8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More

Most Useful Reviews

7.5
Effective against flu
88 people found this helpful
This supplement is incredible! I've realised how zinc helps maintain my immune system. After being in close quarters with those suffering from flu, I remained unaffected thanks to zinc. It effectively reduced symptoms for my son too, while others around struggled. I highly recommend zinc as a preventative measure during flu season.
Read More
9
Strong immunity boost
11 people found this helpful
This zinc supplement is exceptionally beneficial during the cold and flu season, particularly with the ongoing pandemic. Zinc picolinate has better bioavailability, which I believe reduces illness frequency. I use it daily with vitamin D3, ensuring that I manage the dosage correctly, making it an essential part of my health regimen.
Read More
9
Quick immune recovery
10 people found this helpful
Excellent zinc product! I find it easy to absorb and less toxic. I take it to support immunity, especially during the autumn-winter months, and it helps combat colds and flu. The combination of zinc, vitamin C, and D has significantly improved our recovery times, making it a consistent part of my family's health routine.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
  • All Researches
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.

Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.

We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.

Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
Read More
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.

A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.

The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.

However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
Read More
8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 166 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Effective against flu
88 people found this helpful
This supplement is incredible! I've realised how zinc helps maintain my immune system. After being in close quarters with those suffering from flu, I remained unaffected thanks to zinc. It effectively reduced symptoms for my son too, while others around struggled. I highly recommend zinc as a preventative measure during flu season.
Read More
9
Strong immunity boost
11 people found this helpful
This zinc supplement is exceptionally beneficial during the cold and flu season, particularly with the ongoing pandemic. Zinc picolinate has better bioavailability, which I believe reduces illness frequency. I use it daily with vitamin D3, ensuring that I manage the dosage correctly, making it an essential part of my health regimen.
Read More
9
Quick immune recovery
10 people found this helpful
Excellent zinc product! I find it easy to absorb and less toxic. I take it to support immunity, especially during the autumn-winter months, and it helps combat colds and flu. The combination of zinc, vitamin C, and D has significantly improved our recovery times, making it a consistent part of my family's health routine.
Read More
9
Effective flu prevention
10 people found this helpful
NOW is my family's favourite brand. The zinc I've used for a long time really impacts my health. Over the past year, I've not had the flu, and during the COVID-19 pandemic, I never contracted the virus. I take zinc with vitamin D3 (10000iu) and K2 (180mcg). I feel remarkably healthy and hope my experience helps others.
Read More
7.5
Unexpected Benefits
5 people found this helpful
This has helped me in more ways than I anticipated. I purchased it for flu season, but it also aided with fatigue from my autoimmune disease, and unexpectedly alleviated many premenopausal symptoms. I’ve also noticed it helped with a cold. I carefully regulate my zinc intake and have my husband on it for his allergy issues. I highly recommend trying it; it truly worked for me.
Read More

Frequently Asked Questions

10
Flu relief experienced
Amazing! When I had diarrhoea, it abruptly ceased after I took zinc picolinate. And when I had flu, it disappeared swiftly after I took zinc. Truly amazing.
10
Prevents illness
Since I started taking zinc capsules, I haven't contracted the flu or even a cold.
9
Quick immune recovery
10 people found this helpful
Excellent zinc product! I find it easy to absorb and less toxic. I take it to support immunity, especially during the autumn-winter months, and it helps combat colds and flu. The combination of zinc, vitamin C, and D has significantly improved our recovery times, making it a consistent part of my family's health routine.
10
Flu free for years
This is an excellent immunomodulator. After two years of taking zinc polyconate, I have not had the flu! The small pills are easy to take and there's no discomfort or unpleasant taste. I’m thoroughly satisfied with the product's natural composition, and my immunity has clearly improved—it's become my favourite.
9
Immune system support
Zinc is essential for immune support. Upon feeling unwell, I take zinc with vitamin C, which alleviates symptoms. I recommend it, especially during flu season. The capsules’ size and packaging are convenient, and the quality is excellent.
7.5
Effective against flu
88 people found this helpful
This supplement is incredible! I've realised how zinc helps maintain my immune system. After being in close quarters with those suffering from flu, I remained unaffected thanks to zinc. It effectively reduced symptoms for my son too, while others around struggled. I highly recommend zinc as a preventative measure during flu season.
9
Effective flu prevention
10 people found this helpful
NOW is my family's favourite brand. The zinc I've used for a long time really impacts my health. Over the past year, I've not had the flu, and during the COVID-19 pandemic, I never contracted the virus. I take zinc with vitamin D3 (10000iu) and K2 (180mcg). I feel remarkably healthy and hope my experience helps others.
9
Fights infections
Zinc is a robust defender against all cold and flu-related issues. When used alongside Quercetin, it plays a role in combating viral infections and respiratory concerns, including colds.
9
No winter flu
2 people found this helpful
Taking zinc boosts the immune system and I rarely catch colds or flu during winter. I take 50 mg at night with my other supplements and have remained illness-free. Remember not to exceed 100 mg daily from all sources. While zinc can be taken at any time, I appreciate its ability to improve sleep.
8
Shortens flu recovery
3 people found this helpful
Essential for the immune system and respiratory illnesses! Zinc is a great aid for respiratory issues. Sambucus is packed with zinc, or you can opt for a synthetic variant. It helps prevent flu or colds, and if you already have one, it shortens recovery time. This mineral boosts the immune system, and it’s wise to add Vitamin C and D3 as well. These capsules are easy to swallow and don't cause an upset stomach; just ensure you take them with or after meals.
9
Strong immunity boost
11 people found this helpful
This zinc supplement is exceptionally beneficial during the cold and flu season, particularly with the ongoing pandemic. Zinc picolinate has better bioavailability, which I believe reduces illness frequency. I use it daily with vitamin D3, ensuring that I manage the dosage correctly, making it an essential part of my health regimen.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.

A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.

The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.

However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.

Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.

We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.

Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.

References

  1. Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. 10.1371/journal.pone.0316807
  2. Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. 10.21873/invivo.12967
  3. Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. 10.3390/ph15030377
  4. Nakashima A, Horio Y, Suzuki K, Isegawa Y. Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus. Nutrients. 2021;13. 10.3390/nu13113911
  5. Sadeghsoltani F, Mohammadzadeh I, Safari MM, Hassanpour P, Izadpanah M, et al. Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation. Biol Trace Elem Res. 2022;200:2556. 10.1007/s12011-021-02859-z
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