Lactococcus lactis enhances toxin immunityOral immunization of mice with Lactococcus lactis expressing Shiga toxin truncate confers enhanced protection against Shiga toxins of Escherichia coli O157:H7 and Shigella dysenteriae.
We explored the potential of Lactococcus lactis (L. lactis) as an oral vaccine to fight against harmful Shiga toxins produced by bacteria such as E. coli O157:H7 and Shigella dysenteriae. In our study with BALB/c mice, those immunized with a specific strain of L. lactis showed impressive protection, with survival rates of 84% and 100% when exposed to these toxins. The immunization resulted in significant antibody production and minimized organ damage, demonstrating L. lactis's promising role in developing an effective oral vaccine against these toxins.
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Lactococcus lactis reduces food toxinsAnti-Staphylococcal Enterotoxinogenesis of in Algerian Raw Milk Cheese.
We investigated how a specific strain of Lactococcus lactis can help prevent food poisoning caused by a common pathogen found in raw milk and cheese. Our results showed a significant decrease in pathogen levels—by around 3 log CFU/mL—within just six hours when this strain was present.
Even more promising, it reduced the production of staphylococcal enterotoxin A (SEA) by 79%. In cheeses made with Lactococcus lactis, SEA was never detected, while it was found in higher levels in cheeses made without this protective strain. This study clearly shows Lactococcus lactis's potential in enhancing food safety through biopreservation.
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Lactococcus lactis vaccine shows efficacyOral immunization with Lactococcus lactis secreting attenuated recombinant staphylococcal enterotoxin B induces a protective immune response in a murine model.
We explored how Lactococcus lactis, when engineered to produce a harmless version of staphylococcal enterotoxin B (SEB), can offer protection against food poisoning caused by Staphylococcus aureus. In our study, mice that received the oral vaccine developed strong immune responses and were better able to survive challenging infections. Those immunized had significantly reduced bacterial counts in their spleen and higher levels of protective antibodies. This promising approach highlights the potential of using modified bacteria as vaccines against foodborne illnesses.
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Lactobacillus aids gut health during infectionsProbiotic/prebiotic correction for adverse effects of iron fortification on intestinal resistance to Salmonella infection in weaning mice.
We aimed to find out if probiotic supplements like lactobacillus acidophilus could help counteract the negative effects of iron fortification, which has been linked to increased diarrhea and food poisoning among children.
In our study with weaning mice, we discovered that high iron diets led to more severe symptoms when infected with Salmonella.
However, when we added lactobacillus acidophilus beforehand, the mice showed less severe symptoms and better intestinal health.
This suggests that probiotics can really help protect gut health against the adverse effects of iron supplements during foodborne infections.
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Probiotics reduce Salmonella colonizationEvaluation of avian-specific probiotic and Salmonella enteritidis-, Salmonella typhimurium-, and Salmonella heidelberg-specific antibodies on cecal colonization and organ invasion of Salmonella enteritidis in broilers.
We looked at how an avian-specific probiotic could help reduce food poisoning risks linked to Salmonella Enteritidis in poultry. Our study used chicks that received a special probiotic treatment and compared them to a control group.
The results showed a marked decrease in Salmonella Enteritidis colonization in the treated chicks over several days, especially at days 3, 7, and beyond. However, body weight gains appeared similar between both groups.
Overall, our findings suggest that using Lactobacillus acidophilus as part of the treatment may effectively lower Salmonella risks in broilers.
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