'
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
7
Vitamin E (as dl-Alpha tocopheryl acetate)
68 mg
453%
Coenzyme Q10
100 mg
**

The product is found useful for the following medical conditions

Heart Attack details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.6
USERS' SCORE
Good
Based on 10 Reviews
8.8
9
Coenzyme Q10 aids heart recovery
Coenzyme Q10 Modulates Remodeling Possibly by Decreasing Angiotensin-Converting Enzyme in Patients with Acute Coronary Syndrome.
Most Relevant Research
We investigated how coenzyme Q10 might help with heart function after a heart attack, particularly focusing on its role in heart remodeling. In a well-structured study involving 55 patients with left ventricular dysfunction following an acute myocardial infarction, we compared the effects of coenzyme Q10 to a placebo over a 24-week period.

Through careful measurements using echocardiography, we observed notable improvements in the walls of the heart and overall heart mass for those taking coenzyme Q10. Specifically, the thickness of the heart walls decreased, and the left ventricular mass was reduced more significantly than in those receiving the placebo.

Additionally, coenzyme Q10 appeared to maintain heart shape and prevent worsening of heart function compared to the placebo group. Our results also highlighted a significant drop in angiotensin-converting enzyme (ACE) levels in the coenzyme Q10 group, suggesting beneficial effects on heart remodeling and function during recovery from a heart attack.
10
A-Fib support
Most Useful Review
I have A-Fib, and my cardiologist advised me to take CoQ10. This is the best product I've found.

Heart Disease details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 41 Reviews
8.8
9
CoQ-10 improves heart failure outcomes
Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis.
Most Relevant Research
We explored the effectiveness of coenzyme Q10, commonly known as CoQ-10, in treating heart failure (HF) by reviewing multiple studies. Our systematic analysis included research from respected databases like MEDLINE and the Cochrane Library, where we focused on three main outcomes: heart failure-related mortality, exercise capacity, and left ventricular ejection fraction (LVEF).

From the 16 studies we examined, we observed that CoQ-10 treatment significantly decreased HF-related mortality by an impressive 40%. Additionally, we noted improvements in exercise capacity among patients, indicating that CoQ-10 could help individuals with heart failure engage in more physical activity and improve their quality of life.

However, when it came to LVEF—the measurement of how well the heart pumps blood—CoQ-10 did not show significant changes. Despite this, we believe that its potential impact on LVEF should be investigated further, as the data does suggest there may be benefits that warrant additional research.

In summary, while CoQ-10 proved to be beneficial in enhancing exercise capacity and reducing mortality associated with heart failure, the exact effects on LVEF remain unclear and would benefit from more focused studies in the future.
9.5
Supports heart health
Most Useful Review
Excellent for heart health. My elderly parents adore this CoQ10 brand, valuable for their heart disease, high cholesterol, and blood pressure management. I too have benefited when feeling fatigued; it provides a boost I can't get from multivitamins. Our family wholeheartedly recommends this product, as it is well-absorbed compared to regular CoQ10 forms.

High Cholesterol details

SCIENTIFIC SCORE
Possibly Effective
Based on 12 Researches
7.2
USERS' SCORE
Good
Based on 11 Reviews
8.8
9
CoQ10 lowers cholesterol levels
Effects of Coenzyme Q10 Supplementation on Lipid Profiles in Adults: A Meta-analysis of Randomized Controlled Trials.
Most Relevant Research
We delved into the effects of coenzyme Q10 (CoQ10) supplementation on cholesterol levels in adults to determine how it can influence lipid profiles. Through a thorough meta-analysis of fifty randomized controlled trials involving nearly 2800 participants, we explored its potential benefits for reducing cholesterol levels effectively.

Our findings indicated that CoQ10 supplementation significantly lowered levels of total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), and triglycerides (TG), while simultaneously increasing high-density lipoprotein cholesterol (HDL-C). This effect was particularly pronounced at a dosage of 400 to 500 mg per day, which was shown to produce the best results in terms of reducing TC.

Overall, the study provided strong evidence that CoQ10 could be a valuable ally in managing high cholesterol, helping to achieve a healthier lipid profile in adults. This research sheds light on a promising dietary supplement that might assist individuals seeking to improve their cholesterol levels effectively.
8.8
Youthful appearance
Most Useful Review
This is my favourite product that I have used for years. It's helpful for blood pressure and cholesterol. I take one pill twice daily, and people often comment that I look younger than my age, thanks to this supplement. I’m delighted to have found it on iHerb due to their fast shipping and excellent prices!

Cardiovascular Disease details

SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
USERS' SCORE
Good
Based on 25 Reviews
8.6
9
CoQ-10 reduces mortality, improves capacity
Evaluating the efficacy of ubiquinol in heart failure patients: a systematic review and meta-analysis.
Most Relevant Research
We explored the effects of coenzyme Q10 (CoQ-10) on heart failure (HF) patients by analyzing past literature. Our systematic review examined studies from MEDLINE and the Cochrane Library, focusing on how CoQ-10 influences outcomes like HF-related mortality, exercise capacity, and left ventricular ejection fraction (LVEF).

The results from 16 studies showed some promising findings. CoQ-10 was found to significantly lower HF-related mortality by 40%, which is a notable benefit for patients. Additionally, we observed improvements in exercise capacity for those taking CoQ-10. However, when it came to the impact on LVEF, the results were not statistically significant. While there wasn’t a clear-cut improvement in LVEF, we acknowledge that this aspect needs further exploration to fully understand CoQ-10's potential.

In summary, CoQ-10 appears to be effective in reducing mortality rates and enhancing exercise capacity among heart failure patients. Nonetheless, the effect on LVEF is still uncertain and merits additional investigation.
9.5
Heart health boost
Most Useful Review
Excellent for cardiovascular disease. My senior parents have long been fans of this CoQ10 brand recommended by their doctor. It supports their heart health, especially after procedures like angioplasty and open-heart surgery. I've tried it myself when feeling stressed, and it provides a boost in energy and heart health that I can’t get from regular vitamins. Our family highly endorses this product, as it is better absorbed than standard CoQ10 forms.

Alzheimer details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 1 Review
8.6
8
Ubiquinol may combat Alzheimer's effects
Spatial and Temporal Protein Modules Signatures Associated with Alzheimer Disease in 3xTg-AD Mice Are Restored by Early Ubiquinol Supplementation.
Most Relevant Research
We explored the effects of ubiquinol, a form of coenzyme Q10, on Alzheimer's disease through a model using 3xTG-AD mice. Our research aimed to understand how disrupted protein modules in the brain correlate with the progression of Alzheimer's, particularly in terms of oxidative stress and protein regulation.

By employing advanced techniques like MALDI-MSI and functional bioinformatics, we examined how these protein modules are altered based on the age of the mice. We found significant deregulation in specific protein modules related to oxidative stress and metabolism, especially in the hippocampus of younger mice (6 months old) and in the cortical regions of older mice (12 months old). This suggests that early intervention might be crucial to address these changes.

Remarkably, we observed that introducing ubiquinol at an early stage could help restore these protein modules back to a healthier state. This is exciting because it means dietary adjustments, particularly an increase in ubiquinol, could be beneficial in preventing the progression of Alzheimer’s symptoms, both in mice and potentially in humans.

Our findings not only highlight the impact of early dietary intervention but also reinforce the significance of exploring coenzyme Q10 and its benefits for brain health as we age. We believe these insights could pave the way for promising new strategies to combat Alzheimer's disease.
9.5
Enhanced brain function
Most Useful Review
Taking Qunol CoQ10 has greatly improved my energy and skin appearance. I apply it daily, and the results are remarkable. Before, my brain felt foggy, but after consistent use, I’ve experienced clearer thinking, and those around me have noticed the change. This supplement fights alzheimer's and promotes overall well-being. I will be a lifelong customer.

Anemia details

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Good
Based on 1 Review
8.6
9
Coenzyme Q10 aids anemia treatment
The anemia of vitamin E deficiency in swine: an experimental model of the human congenital dyserythropoietic anemias.
Most Relevant Research
We explored the characteristics of anemia caused by vitamin E deficiency in pigs to see how it might serve as a model for human congenital dyserythropoietic anemia (CDA). In this study, we found that the main issue in these pigs was ineffective erythropoiesis, similar to what some humans experience with CDA.

Strikingly, we observed increases in certain erythrocyte enzymes in these pigs, paralleling changes noted in CDA patients. In the animals, distinctive structural alterations similar to those seen in human cases were present in normoblasts, the precursors to red blood cells.

A notable finding was that administering coenzyme Q10, alongside vitamin E, led to a complete hematologic response in the pigs. This suggests that coenzyme Q10 could play a significant role in addressing anemia related to vitamin E deficiency. However, the partial response noted after adjusting the diet indicates that there may be more factors at play in this disorder’s development.

Overall, coenzyme Q10 appears to have a beneficial impact on treating anemia in this swine model, indicating potential avenues for further research in human applications.
9.5
Improved energy levels
Most Useful Review
It really WORKS. It’s the BEST of the BEST! At 71, I've been exhausted for over a decade due to chronic anaemia. After trying various CoQ10 products that didn't help, I took a chance with this one due to great reviews. Within two weeks, I could tell it worked as long as I took it twice a day. I've been using it for at least two years now. It provides a noticeable boost; I feel energetic without spikes in my blood pressure. This product has dramatically improved my quality of life.

Arthritis details

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.9
USERS' SCORE
Good
Based on 1 Review
8.6
9
CoQ10 shows promise for RA
Effects of coenzyme Q10 supplementation on matrix metalloproteinases and DAS-28 in patients with rheumatoid arthritis: a randomized, double-blind, placebo-controlled clinical trial.
Most Relevant Research
We explored the effects of Coenzyme Q10 (CoQ10) supplementation on rheumatoid arthritis (RA) patients in a well-structured study. Fifty-four individuals diagnosed with RA were divided into two groups: one received 100 mg of CoQ10 daily, while the other group received a placebo for two months. This randomized and double-blind setup helped ensure that the findings would be credible and free from bias.

Our findings revealed some noteworthy changes in the CoQ10 group. There was a significant reduction in serum levels of matrix metalloproteinase-3 (MMP-3), which is linked to inflammation and tissue remodeling, alongside improvements in clinical indicators like swollen joint count and the disease activity score (DAS-28). Essentially, participants taking CoQ10 experienced a decrease in pain levels and tenderness in their joints, suggesting that CoQ10 may offer additional benefits for managing RA symptoms.

However, the study also showed slight improvements in the placebo group, indicating that factors like natural variability and placebo effects could play a role in treatment outcomes. While CoQ10 touted some advantages over the placebo, the reduction in MMP-3 levels signifies a potentially therapeutic area worth further exploration.

In conclusion, CoQ10 may serve as a complementary approach for those dealing with the challenges of rheumatoid arthritis, supporting both clinical symptoms and biomarkers of inflammation.
9.5
Impressive results
Most Useful Review
Very good product. I use this for two issues; I can't take statins (which I need) due to the muscle pain they cause in my legs. I also have osteoarthritis which is severely painful, especially in my fingers. I was hesitant to use prescribed meds for arthritis due to potential side effects. After researching, I decided to try Qunol Ultra CoQ10. Initially, another brand was ineffective, but Qunol has worked wonders without leg pain, and I now take it alongside turmeric for arthritis. I’m thrilled with the results; my fingers rarely ache now. I even shared this miracle treatment with a friend who was amazed by how quickly it alleviated her arthritis pain.

Cancer details

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.8
USERS' SCORE
Good
Based on 1 Review
8.6
9
CoQ10 mitigates chemobrain effects
Coenzyme Q10 ameliorates cyclophosphamide-induced chemobrain by repressing neuronal apoptosis and preserving hippocampal neurogenesis: Mechanistic roles of Wnt/ β-catenin signaling pathway.
Most Relevant Research
We explored the potential benefits of Coenzyme Q10 (CoQ10) on cancer patients dealing with a condition commonly referred to as "Chemobrain," which is associated with treatment using the chemotherapy drug cyclophosphamide (CYP). In our study, male rats were given a daily dose of CoQ10 for ten days, while they also received a single dose of CYP to model the effects of chemotherapy on cognition and motor skills.

The findings were promising. CoQ10 not only helped counteract cognitive and motor dysfunctions triggered by CYP but also showed significant neuroprotective effects. Behavioral tests demonstrated improvements, and histopathological analysis confirmed that CoQ10 reduced brain damage linked to oxidative stress caused by CYP. This micronutrient effectively restored levels of the antioxidant enzyme catalase and lowered harmful substances like malondialdehyde.

Furthermore, CoQ10 appeared to inhibit neuronal apoptosis, or cell death, by balancing expressions of key proteins involved in the process. It supported neurogenesis in the hippocampus by increasing important growth factors. Most notably, CoQ10 activated the Wnt/β-catenin signaling pathway, which is crucial for brain health and development.

Overall, our study highlights how CoQ10 may offer a multi-faceted approach to mitigating the adverse effects of chemotherapy on cognitive function, bolstering both brain protection and regeneration.
9.5
Boosted overall health
Most Useful Review
Taking Qunol CoQ10 has been a staple in my daily regimen for years. It significantly boosts my energy levels and has improved my exercise performance. I've noticed a healthy glow to my skin without needing makeup. Furthermore, it helps in the fight against cancer, Alzheimer's, and Parkinson's, protecting vital organs. Since I started taking it, I've felt markedly more alert and productive. Qunol CoQ10 has made a tremendous difference, making me a lifelong believer.

Hypertension details

SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 1 Review
8.6
7
Citicoline and CoQ10 protection study
Neuroprotective Effect of the Combination of Citicoline and CoQ10 in a Mouse Model of Ocular Hypertension.
Most Relevant Research
We investigated how a combination of citicoline and coenzyme Q10 (CoQ10) might impact retinal cell health in a mouse model of ocular hypertension (OHT). Using four groups of mice, including those receiving the combination treatment and a control group, we aimed to understand if these substances could protect against the loss of retinal ganglion cells, which is a major concern in glaucoma.

The treatment was started 15 days prior to inducing ocular hypertension with a laser and continued until we examined the mice about a week later. Our findings were promising: the combination of citicoline and CoQ10 led to a temporary reduction in eye pressure shortly after treatment. Furthermore, it significantly prevented the death of specific retinal cells that are vital for vision.

While we were encouraged by these results, especially regarding cell protection, it's important to note that there were no significant impacts on neurons in the visual pathway areas we studied, like the dLGN. Overall, our research suggests that this combination might offer neuroprotective benefits in specific aspects of ocular hypertension, paving the way for further exploration into treatments that go beyond only lowering eye pressure.
9.5
Normal blood pressure
Most Useful Review
After struggling with hypertension averaging 140/90 to 150/100, I returned to CoQ10, which I had previously used effectively. Within a week of taking this brand, my resting blood pressure is now around 125/72. I’m relieved to have finally gained control of my hypertension, prioritising my health for my family.

Pelvic Pain details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
9
Joint pain relief
Most Useful Review
If you take statins, this is the best option as it alleviated the joint pain caused by the statins I take.

Headache details

SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 1 Review
8.5
8
Coenzyme Q10 shows effectiveness against migraines
A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial.
Most Relevant Research
We investigated the effectiveness of coenzyme Q10 in treating migraines in children, comparing it with the commonly prescribed medication, amitriptyline. Our study involved 72 children, aged 5 to 15, who met the criteria for migraine diagnosis set by the International Headache Society.

Over a three-month period, we observed that coenzyme Q10 had positive therapeutic effects, particularly for those requiring long-term treatment. While amitriptyline provided quicker results, the differences between the two treatments in effectiveness were not significantly noticeable after three months. Both treatments led to improvements in the quality of life for the children involved.

Importantly, we noted that children taking amitriptyline experienced more side effects compared to those receiving coenzyme Q10. This finding positions coenzyme Q10 as a promising option due to its comparable effectiveness and better tolerated adverse effect profile.
8.8
Reduced headache intensity
Most Useful Review
Better absorbency appears to be true according to comparisons. Our family uses Co-Q10 due to chronic migraines. This brand seems to be absorbed better, as noted by relatives who reported their headaches feel less intense after switching from other brands. A relative—a maximum dosage user—sometimes finds his headache completely goes away. However, my husband still experienced no change in the frequency of headaches until we adjusted his dosage timings, which has noticeably reduced the frequency while muting severe pain.

Leg Cramps details

SCIENTIFIC SCORE
No researches found
N/A
USERS' SCORE
Good
Based on 2 Reviews
8.5
10
Fast relief
Most Useful Review
Very easy to swallow. I've taken these CO-Q10 tablets for over 10 years to alleviate the side effects of statins. Recommended by my doctor after starting Lipitor due to severe leg cramps. Within 2-4 hours of taking 200mg of CO-Q10, my leg cramps disappeared, and they've never returned.

Migraine details

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 1 Review
8.5
8
Co-Q10 potentially benefits migraine patients
The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial.
Most Relevant Research
We investigated how Coenzyme Q10 (Co-Q10) affects migraine symptoms in a well-structured clinical trial. Over the course of 12 weeks, 84 women aged 18 to 50 diagnosed with episodic migraines participated in a randomized, double-blind study, where they received either Co-Q10 (400 mg/day) or a placebo.

Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.

However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
8.8
Better absorption noted
Most Useful Review
Seems better absorbency is true per comparisons. Our family uses Co-Q10 for chronic migraines, which run in our family. This brand seems better absorbed than others—we have noticed fewer intense headaches. Two relatives reported their headaches feel less severe after switching to this brand. A third relative uses maximum dosage to sometimes completely eliminate headaches. We've seen significant results while following our neurologist's advice on dosages.

Dizziness details

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 1 Review
8.4
7
CoQ10's uncertain effects on dizziness
Role of coenzyme Q10 (CoQ10) in cardiac disease, hypertension and Meniere-like syndrome.
Most Relevant Research
We explored the potential benefits of coenzyme Q10 (CoQ10) in addressing dizziness associated with Meniere-like syndrome. CoQ10 is known to play a crucial role in energy production within cells, particularly those in the heart, and it has been observed to have various health benefits.

In our review of the available research, we noted that CoQ10 may help improve immune function, which can indirectly assist individuals experiencing symptoms like vertigo or dizziness. While there is recognition of CoQ10's positive effects on heart health, the specific impact on dizziness remains somewhat uncertain.

We found that although trials suggested improvements in various cardiovascular conditions, the isolated effectiveness of CoQ10 for treating dizziness specifically wasn't definitively established in the studies reviewed. Thus, we remain cautiously optimistic about its potential while emphasizing the need for further research.
7
Controlled dizziness
Most Useful Review
After struggling with hypertension, my blood pressure was alarmingly high. Traditional medications caused unbearable side effects, and I felt generally unwell. About three weeks ago, I decided to try this brand of coq10. Within a week, my resting BP is much improved, and I've experienced morning dizziness less frequently. I'm relieved to have it under control for the sake of my family.
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