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SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
7
Vitamin E (as dl-Alpha tocopheryl acetate)
68 mg
453%
Coenzyme Q10
100 mg
**
Top Medical Research Studies
8
Co-Q10 potentially benefits migraine patients
The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial.
Study focused on Co-Q10's effects
We investigated how Coenzyme Q10 (Co-Q10) affects migraine symptoms in a well-structured clinical trial. Over the course of 12 weeks, 84 women aged 18 to 50 diagnosed with episodic migraines participated in a randomized, double-blind study, where they received either Co-Q10 (400 mg/day) or a placebo.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
Read More
8
Coenzyme Q10 shows promise in migraine
A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial.
Directly compares treatment options
We explored the use of coenzyme Q10 as a preventive treatment for migraine headaches in children aged 5 to 15. Conducted as a randomized controlled trial with 72 participants, we aimed to compare how effectively coenzyme Q10 works against a commonly used medication, amitriptyline. Both treatments were assessed for their impact on the frequency, duration, and severity of migraines, as well as improvements in children's quality of life.
Our findings revealed that coenzyme Q10 offered encouraging long-term benefits for managing migraines, showing notable efficacy particularly over extended periods. While amitriptyline responded more quickly, the side effects were more pronounced in children taking this medication. Interestingly, after three months of treatment, both groups exhibited similar clinical outcomes and enhancements in quality of life.
Overall, we determined that coenzyme Q10 could serve as a viable alternative for migraine prophylaxis, given its favorable side effect profile and comparable effectiveness to traditional treatments like amitriptyline.
Our findings revealed that coenzyme Q10 offered encouraging long-term benefits for managing migraines, showing notable efficacy particularly over extended periods. While amitriptyline responded more quickly, the side effects were more pronounced in children taking this medication. Interestingly, after three months of treatment, both groups exhibited similar clinical outcomes and enhancements in quality of life.
Overall, we determined that coenzyme Q10 could serve as a viable alternative for migraine prophylaxis, given its favorable side effect profile and comparable effectiveness to traditional treatments like amitriptyline.
Read More
8
CoQ10's effectiveness in migraine prevention
Metabolic treatments of migraine.
Highly relevant migraine treatment insight
Our investigation into coenzyme Q10 (CoQ10) as a potential treatment for migraines reveals encouraging findings. We found that this supplement can play a role in preventing migraine headaches, offering a well-tolerated option for many who suffer from this debilitating condition.
What’s particularly appealing is that CoQ10 appears to boast similar response rates to more commonly prescribed medications like topiramate and propranolol, without the hefty price tag or adverse side effects associated with some newer therapies.
Additionally, CoQ10 is associated with minimal risk, making it an attractive first-line treatment for many patients, including children and adolescents. With the growing interest in holistic approaches to health, CoQ10 provides an effective, inexpensive alternative that underscores the importance of metabolic treatments in managing migraines.
What’s particularly appealing is that CoQ10 appears to boast similar response rates to more commonly prescribed medications like topiramate and propranolol, without the hefty price tag or adverse side effects associated with some newer therapies.
Additionally, CoQ10 is associated with minimal risk, making it an attractive first-line treatment for many patients, including children and adolescents. With the growing interest in holistic approaches to health, CoQ10 provides an effective, inexpensive alternative that underscores the importance of metabolic treatments in managing migraines.
Read More
Most Useful Reviews
8.8
Better absorption noted
Seems better absorbency is true per comparisons. Our family uses Co-Q10 for chronic migraines, which run in our family. This brand seems better absorbed than others—we have noticed fewer intense headaches. Two relatives reported their headaches feel less severe after switching to this brand. A third relative uses maximum dosage to sometimes completely eliminate headaches. We've seen significant results while following our neurologist's advice on dosages.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.1
8
Coenzyme Q10 improves migraine symptoms
Eyebrow bleeding as a rare migraine symptom: a case report.
Moderate relevance to treatment effectiveness
We examined a unique case involving a 10-year-old girl who experienced eyebrow bleeding linked to her migraine episodes. Despite conducting thorough neurological examinations and imaging studies that returned normal results, the young patient faced recurrent, intense headaches accompanied by unusual symptoms such as bleeding around her eyebrows and red spots on her forehead.
These atypical signs suggest that her migraines may be influenced by underlying neurovascular and neuroinflammatory processes. Given the complexity of her symptoms, this case highlights the need for healthcare providers to remain vigilant and consider various manifestations of migraines.
Treatment involved using Coenzyme Q10 alongside Vitamin B2 and Cyproheptadine, leading to noticeable improvements in the frequency and intensity of her headaches. This case not only emphasizes the importance of recognizing uncommon migraine symptoms but also showcases how a combination of treatments could potentially benefit young patients suffering from migraines.
These atypical signs suggest that her migraines may be influenced by underlying neurovascular and neuroinflammatory processes. Given the complexity of her symptoms, this case highlights the need for healthcare providers to remain vigilant and consider various manifestations of migraines.
Treatment involved using Coenzyme Q10 alongside Vitamin B2 and Cyproheptadine, leading to noticeable improvements in the frequency and intensity of her headaches. This case not only emphasizes the importance of recognizing uncommon migraine symptoms but also showcases how a combination of treatments could potentially benefit young patients suffering from migraines.
Read More
8
Coenzyme Q10 for migraine relief
Practical supplements for prevention and management of migraine attacks: a narrative review.
Moderate relevance; mixed findings.
We aimed to understand how coenzyme Q10 affects migraine symptoms. This review highlighted that low levels of essential nutrients, including coenzyme Q10, may influence the severity and frequency of migraine attacks.
Our investigation revealed that oxidative stress and inflammation contribute to migraines. Coenzyme Q10 is noted for its role in mitochondrial function, which is vital for energy production in our cells. By supporting these processes, coenzyme Q10 could potentially alleviate migraine episodes.
Evidence from various studies indicated that coenzyme Q10 supplementation could lead to a reduction in migraine frequency and intensity. While we saw promising results, it’s clear that further prospective studies are necessary to establish a more definitive understanding of its effects.
Our investigation revealed that oxidative stress and inflammation contribute to migraines. Coenzyme Q10 is noted for its role in mitochondrial function, which is vital for energy production in our cells. By supporting these processes, coenzyme Q10 could potentially alleviate migraine episodes.
Evidence from various studies indicated that coenzyme Q10 supplementation could lead to a reduction in migraine frequency and intensity. While we saw promising results, it’s clear that further prospective studies are necessary to establish a more definitive understanding of its effects.
Read More
8
Nonprescription therapies for vestibular migraine
Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study.
Effectiveness of combined treatment unclear
We conducted a questionnaire-based examination to understand the effects of nonprescription therapies, particularly focusing on coenzyme Q10, on vestibular migraine (VM) symptoms. Our research involved 82 participants diagnosed with VM who were given guidance on improving sleep, hydration, exercise, and nutrition, alongside a combination supplement that included coenzyme Q10.
After three months of treatment, we found that participants experienced a significant reduction in the severity and frequency of their symptoms. The results indicated improvements across various measures, suggesting that these nonprescription therapies, which included coenzyme Q10, could help manage VM symptoms.
Notably, half of the patients reported an improvement in their dizziness handicap and vertigo-specific symptoms. While the use of this supplement appears to offer benefits, it is essential to highlight that our study did not isolate the specific impact of coenzyme Q10 alone, making it difficult to draw definitive conclusions about its effectiveness in treating migraine.
Overall, our findings provide valuable insights that suggest the potential for nonprescription therapies in alleviating vestibular migraine symptoms, warranting further investigation into the specific contributions of each component, including coenzyme Q10.
After three months of treatment, we found that participants experienced a significant reduction in the severity and frequency of their symptoms. The results indicated improvements across various measures, suggesting that these nonprescription therapies, which included coenzyme Q10, could help manage VM symptoms.
Notably, half of the patients reported an improvement in their dizziness handicap and vertigo-specific symptoms. While the use of this supplement appears to offer benefits, it is essential to highlight that our study did not isolate the specific impact of coenzyme Q10 alone, making it difficult to draw definitive conclusions about its effectiveness in treating migraine.
Overall, our findings provide valuable insights that suggest the potential for nonprescription therapies in alleviating vestibular migraine symptoms, warranting further investigation into the specific contributions of each component, including coenzyme Q10.
Read More
8
Co-Q10 potentially benefits migraine patients
The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial.
Study focused on Co-Q10's effects
We investigated how Coenzyme Q10 (Co-Q10) affects migraine symptoms in a well-structured clinical trial. Over the course of 12 weeks, 84 women aged 18 to 50 diagnosed with episodic migraines participated in a randomized, double-blind study, where they received either Co-Q10 (400 mg/day) or a placebo.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
Upon analyzing the results, we observed some promising outcomes. Participants who took Co-Q10 experienced a significant reduction in malondialdehyde (MDA) levels, an indicator of oxidative stress. Additionally, there was a noteworthy increase in high-density lipoprotein cholesterol (HDL-C) levels, which is beneficial for overall heart health. We also noted a decrease in body fat percentage among those receiving Co-Q10.
However, while some improvements were documented, Co-Q10 did not show a significant effect on total antioxidant capacity or other lipid profile measures like low-density lipoprotein cholesterol and triglycerides. Therefore, while Co-Q10 may hold potential for enhancing certain health aspects in migraine sufferers, its overall impact on migraine management and other related parameters remains mixed.
Read More
8
Coenzyme Q10 shows promise in migraine
A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial.
Directly compares treatment options
We explored the use of coenzyme Q10 as a preventive treatment for migraine headaches in children aged 5 to 15. Conducted as a randomized controlled trial with 72 participants, we aimed to compare how effectively coenzyme Q10 works against a commonly used medication, amitriptyline. Both treatments were assessed for their impact on the frequency, duration, and severity of migraines, as well as improvements in children's quality of life.
Our findings revealed that coenzyme Q10 offered encouraging long-term benefits for managing migraines, showing notable efficacy particularly over extended periods. While amitriptyline responded more quickly, the side effects were more pronounced in children taking this medication. Interestingly, after three months of treatment, both groups exhibited similar clinical outcomes and enhancements in quality of life.
Overall, we determined that coenzyme Q10 could serve as a viable alternative for migraine prophylaxis, given its favorable side effect profile and comparable effectiveness to traditional treatments like amitriptyline.
Our findings revealed that coenzyme Q10 offered encouraging long-term benefits for managing migraines, showing notable efficacy particularly over extended periods. While amitriptyline responded more quickly, the side effects were more pronounced in children taking this medication. Interestingly, after three months of treatment, both groups exhibited similar clinical outcomes and enhancements in quality of life.
Overall, we determined that coenzyme Q10 could serve as a viable alternative for migraine prophylaxis, given its favorable side effect profile and comparable effectiveness to traditional treatments like amitriptyline.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8.8
Better absorption noted
Seems better absorbency is true per comparisons. Our family uses Co-Q10 for chronic migraines, which run in our family. This brand seems better absorbed than others—we have noticed fewer intense headaches. Two relatives reported their headaches feel less severe after switching to this brand. A third relative uses maximum dosage to sometimes completely eliminate headaches. We've seen significant results while following our neurologist's advice on dosages.
Read More
