Last update
3/9/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 1 Review
8.4
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
6
Vitamin C (as ascorbyl palmitate)
6 mg
7%
Ubiquinol (Kaneka Ubiquinol®) active form of Coenzyme Q10
100 mg
**
Top Medical Research Studies
7
Ubiquinol shows partial benefits
We explored the impact of ubiquinol on pulmonary hypertension using a model that mimics this serious condition. In our study, rats were injected with monocrotaline, a substance known to induce pulmonary hypertension. Over the course of the experiment, we provided various groups of these rats with different treatments, including solubilized ubiquinol and selenium, to see how these substances could protect against the effects of the disease.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
Read More
Most Useful Reviews
7.5
Assisted hypertension treatment
4 people found this helpful
These supplements seem to help my elderly mother with her hypertension, especially when combined with turmeric, potassium, and quality magnesium. I'm happy to see her health benefits.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
Ubiquinol shows partial benefits
We explored the impact of ubiquinol on pulmonary hypertension using a model that mimics this serious condition. In our study, rats were injected with monocrotaline, a substance known to induce pulmonary hypertension. Over the course of the experiment, we provided various groups of these rats with different treatments, including solubilized ubiquinol and selenium, to see how these substances could protect against the effects of the disease.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
The results were quite enlightening. We observed that ubiquinol administered intravenously had a protective effect, especially in male rats. This treatment reduced the right ventricle hypertrophy and lung mass commonly associated with elevated blood pressure in the lungs. Interestingly, when we combined ubiquinol with selenium, we found a less severe increase in right ventricle systolic pressure in males but not in females, indicating a sex-dependent effect that suggests females may not experience the same benefits from this combination treatment.
However, it's worth noting that the relative mass of the right ventricle did not show significant differences across all treatment groups. This suggests that while ubiquinol can be beneficial, particularly in males, the overall benefits may be limited and not as pronounced in females. Magnetic resonance imaging further revealed impaired lung perfusion in most rats tested, with signs of pulmonary fibrosis only present in the group receiving ubiquinol.
Overall, while ubiquinol shows potential in addressing pulmonary hypertension, its effectiveness might vary based on sex and should be approached with cautious optimism.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Assisted hypertension treatment
4 people found this helpful
These supplements seem to help my elderly mother with her hypertension, especially when combined with turmeric, potassium, and quality magnesium. I'm happy to see her health benefits.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Kuropatkina T, Pavlova O, Gulyaev M, Pirogov Y, Khutorova A, et al. Sex-Dependent Protective Effect of Combined Application of Solubilized Ubiquinol and Selenium on Monocrotaline-Induced Pulmonary Hypertension in Wistar Rats. Antioxidants (Basel). 2022;11. 10.3390/antiox11030549
Data last updated:
