Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 58 Researches
8.1
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.8
Supplement Facts
Serving Size: 1 Capsule
Serving Per Container: 30
Amount Per Serving
%DV
Ultimate Care Probiotic Culture Blend 100 Billion CFU
301 mg
***
Bifido Probiotic BlendBifidobacterium lactis BI-04®, Bifidobacterium lactis HN019™, Bifidobacterium infantis Bi-26™, Bifidobacterium lactis Bi-07®
54 Billion CFU
Lacto Probiotic BlendLactobacillus plantarum Lp-115®, Lactobacillus rhamnosus GG, Lactococcus lactis LI-23™, Lactobacillus casei Lc-11®, Lactobacillus paracasei Lpc-37®, Lactobacillus acidophilus La-14®, Lactobacillus acidophilus NCFM®, Lactobacillus brevis Lbr-35™
46 Billion CFU
Top Medical Research Studies
8
We investigated the impact of a probiotic ice cream containing engineered bacteria on pollen allergies in mice. After sensitizing the mice, we treated them with this unique ice cream for four weeks. The results were promising! The ice cream significantly lowered serum IgE levels, which are linked to allergic reactions. Additionally, beneficial cytokines increased while the levels of a harmful cytokine decreased. Overall, our findings suggest that this probiotic ice cream could improve allergy responses, particularly with Th1 and Treg involvement.
Read More
9
We explored how the probiotic strain CCFM1274 affects allergic asthma symptoms by modifying tryptophan metabolism. Using a mouse model, we administered ovalbumin to induce asthma and treated the mice with CCFM1274. The results were promising; this probiotic reduced both weight loss and mortality in the mice.
We also noticed a drop in specific immunoglobulin E levels and inflammatory cytokines, indicating improved lung health. CCFM1274 appears to help remodel gut metabolism, leading to better management of allergic asthma symptoms as demonstrated in our study.
We also noticed a drop in specific immunoglobulin E levels and inflammatory cytokines, indicating improved lung health. CCFM1274 appears to help remodel gut metabolism, leading to better management of allergic asthma symptoms as demonstrated in our study.
Read More
9
Probiotics beneficial for allergies
Our study asked whether a specific mixture of probiotics could help alleviate allergic rhinitis symptoms in children. We enrolled 250 kids, half receiving the probiotic mixture alongside their regular allergy treatment, and the other half getting a placebo.
The results were promising! Those in the probiotic group experienced a significant reduction in allergy symptoms and less reliance on allergy medications. This evidence suggests that probiotics might be a helpful addition to managing allergic rhinitis in children.
The results were promising! Those in the probiotic group experienced a significant reduction in allergy symptoms and less reliance on allergy medications. This evidence suggests that probiotics might be a helpful addition to managing allergic rhinitis in children.
Read More
Most Useful Reviews
10
Relieved food allergies
5 people found this helpful
A godsend for food allergies. After discovering I am allergic to foods I’ve consumed all my life, I experienced rashes and blisters from seemingly safe foods. The only relief came from certain antibiotics and steroids, which were quite concerning. My GI doctor suggested a probiotic due to the antibiotics I was taking. After a friend's recommendation, I tried it, and within three days, the rashes had vanished. Now, I am able to eat what I want, and I plan to retest for my allergies soon. I highly recommend this for food allergies.
Read More
2
Changed formula problems
18 people found this helpful
Once a great product, it is no longer allergy safe. I am disappointed as this was my go-to probiotic for years. I have numerous food allergies, and it had been difficult to find a probiotic without issues. My doctor recommended taking several each day, making it quite an investment. Unfortunately, they altered the formula, leading to allergic reactions and health flare-ups. It frustrates me that they change a product that many in the allergy community rely on. This once essential product is now no longer safe for me.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 58 Researches
8.1
- All Researches
9.5
We sought to understand if Bifiform Kids, a probiotic, could help prevent respiratory infections in children with recurrent infections and gastrointestinal allergy symptoms. In our controlled trial with 92 children aged 4 to 5, those taking the probiotic showed a significant 3-fold reduction in respiratory infections compared to the control group.
After 21 days, there were notable immune system improvements, including an increase in protective IgA levels and a decrease in allergic IgE. These findings suggest that Bifiform Kids is effective for preventing respiratory infections in children facing allergic issues.
After 21 days, there were notable immune system improvements, including an increase in protective IgA levels and a decrease in allergic IgE. These findings suggest that Bifiform Kids is effective for preventing respiratory infections in children facing allergic issues.
Read More
9
We explored how the probiotic strain CCFM1274 affects allergic asthma symptoms by modifying tryptophan metabolism. Using a mouse model, we administered ovalbumin to induce asthma and treated the mice with CCFM1274. The results were promising; this probiotic reduced both weight loss and mortality in the mice.
We also noticed a drop in specific immunoglobulin E levels and inflammatory cytokines, indicating improved lung health. CCFM1274 appears to help remodel gut metabolism, leading to better management of allergic asthma symptoms as demonstrated in our study.
We also noticed a drop in specific immunoglobulin E levels and inflammatory cytokines, indicating improved lung health. CCFM1274 appears to help remodel gut metabolism, leading to better management of allergic asthma symptoms as demonstrated in our study.
Read More
9
This prospective randomized controlled study involved 92 children aged 4 to 5 with food allergies affecting their skin and gastrointestinal system.
Half of the children received a combined probiotic over 21 days, resulting in reduced allergy symptoms and lower IgE levels compared to the control group.
After treatment, significant improvements in skin conditions and gastrointestinal issues were noted, showcasing the probiotic's potential to alleviate allergy symptoms and rebalance specific immune responses.
Half of the children received a combined probiotic over 21 days, resulting in reduced allergy symptoms and lower IgE levels compared to the control group.
After treatment, significant improvements in skin conditions and gastrointestinal issues were noted, showcasing the probiotic's potential to alleviate allergy symptoms and rebalance specific immune responses.
Read More
9
Probiotics beneficial for allergies
Our study asked whether a specific mixture of probiotics could help alleviate allergic rhinitis symptoms in children. We enrolled 250 kids, half receiving the probiotic mixture alongside their regular allergy treatment, and the other half getting a placebo.
The results were promising! Those in the probiotic group experienced a significant reduction in allergy symptoms and less reliance on allergy medications. This evidence suggests that probiotics might be a helpful addition to managing allergic rhinitis in children.
The results were promising! Those in the probiotic group experienced a significant reduction in allergy symptoms and less reliance on allergy medications. This evidence suggests that probiotics might be a helpful addition to managing allergic rhinitis in children.
Read More
9
We investigated how a daily symbiotic food supplement could affect birch pollen allergies in patients with rhinoconjunctivitis. This study used an allergen exposure chamber, allowing us to standardize pollen exposure and track symptoms effectively.
Over four months, the supplement seemed to enhance patients' overall well-being and significantly improve allergy symptoms during controlled exposures. The findings suggest a promising role for such supplements in managing allergic rhinitis, with a strong safety record.
Over four months, the supplement seemed to enhance patients' overall well-being and significantly improve allergy symptoms during controlled exposures. The findings suggest a promising role for such supplements in managing allergic rhinitis, with a strong safety record.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 2 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
10
Relieved food allergies
5 people found this helpful
A godsend for food allergies. After discovering I am allergic to foods I’ve consumed all my life, I experienced rashes and blisters from seemingly safe foods. The only relief came from certain antibiotics and steroids, which were quite concerning. My GI doctor suggested a probiotic due to the antibiotics I was taking. After a friend's recommendation, I tried it, and within three days, the rashes had vanished. Now, I am able to eat what I want, and I plan to retest for my allergies soon. I highly recommend this for food allergies.
Read More
2
Changed formula problems
18 people found this helpful
Once a great product, it is no longer allergy safe. I am disappointed as this was my go-to probiotic for years. I have numerous food allergies, and it had been difficult to find a probiotic without issues. My doctor recommended taking several each day, making it quite an investment. Unfortunately, they altered the formula, leading to allergic reactions and health flare-ups. It frustrates me that they change a product that many in the allergy community rely on. This once essential product is now no longer safe for me.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
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- Adjibade M, Vigneron L, Delvert R, Adel-Patient K, Divaret-Chauveau A, et al. Characteristics of infant formula consumed in the first months of life and allergy in the EDEN mother-child cohort. Matern Child Nutr. 2024;20:e13673. 10.1111/mcn.13673
- Li L, Wen X, Gong Y, Chen Y, Xu J, et al. HMGN2 and Histone H1.2: potential targets of a novel probiotic mixture for seasonal allergic rhinitis. Front Microbiol. 2023;14:1202858. 10.3389/fmicb.2023.1202858
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- Bergmann KC, Krause L, Hiller J, Becker S, Kugler S, et al. First evaluation of a symbiotic food supplement in an allergen exposure chamber in birch pollen allergic patients. World Allergy Organ J. 2021;14:100494. 10.1016/j.waojou.2020.100494
- Tan-Lim CSC, Esteban-Ipac NAR, Mantaring JBV, Chan Shih Yen E, Recto MST, et al. Comparative effectiveness of probiotic strains for the treatment of pediatric atopic dermatitis: A systematic review and network meta-analysis. Pediatr Allergy Immunol. 2021;32:124. 10.1111/pai.13305
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- Liu Q, Jing W, Wang W. Ameliorates the Risk of Food Allergy in Chinese Children by Affecting Relative Percentage of Treg and Th17 Cells. Can J Infect Dis Med Microbiol. 2018;2018:4561038. 10.1155/2018/4561038
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- Lee MF, Wang NM, Chen YH, Wu CS, Lee MH, et al. An atopic dermatitis-like murine model by skin-brushed cockroach Per a 2 and oral tolerance induction by Lactococcus lactis-derived Per a 2. PLoS One. 2023;18:e0291162. 10.1371/journal.pone.0291162
- Lee JY, Park JY, Jeong Y, Kang CH. Anti-Inflammatory Response in TNFα/IFNγ-Induced HaCaT Keratinocytes and Probiotic Properties of MG4644, MG4693, and MG5474. J Microbiol Biotechnol. 2023;33:1039. 10.4014/jmb.2301.01028
- Baek J, Kim JH, Kim W. Potential Anti-Allergy and Immunomodulatory Properties of LB 1022 Observed In Vitro and in an Atopic Dermatitis Mouse Model. J Microbiol Biotechnol. 2023;33:823. 10.4014/jmb.2301.01019
- Baars T, van Esch B, van Ooijen L, Zhang Z, Dekker P, et al. Raw milk kefir: microbiota, bioactive peptides, and immune modulation. Food Funct. 2023;14:1648. 10.1039/d2fo03248a
- Lee DH, Park HK, Lee HR, Sohn H, Sim S, et al. Immunoregulatory effects of Lactococcus lactis-derived extracellular vesicles in allergic asthma. Clin Transl Allergy. 2022;12:e12138. 10.1002/clt2.12138
- Lee MF, Chiang CH, Lin SJ, Wu CS, Chen YH. Effectiveness and safety of oral lactococci-based vaccine encoding triple common allergens to prevent airway allergy in mice. PLoS One. 2021;16:e0261333. 10.1371/journal.pone.0261333
- El Mecherfi KE, Lupi R, Cherkaoui M, Albuquerque MAC, Todorov SD, et al. Fermentation of Gluten by Lactococcus lactis LLGKC18 Reduces its Antigenicity and Allergenicity. Probiotics Antimicrob Proteins. 2022;14:779. 10.1007/s12602-021-09808-1
- Zhang K, Mirza WA, Ni P, Yu M, Wang C, et al. Recombination Lactococcus lactis expressing Helicobacter pylori neutrophil-activating protein A attenuates food allergy symptoms in mice. FEMS Microbiol Lett. 2021;368. 10.1093/femsle/fnab034
- Cervantes-García D, Jiménez M, Rivas-Santiago CE, Gallegos-Alcalá P, Hernández-Mercado A, et al. Lactococcus lactis NZ9000 Prevents Asthmatic Airway Inflammation and Remodelling in Rats through the Improvement of Intestinal Barrier Function and Systemic TGF-β Production. Int Arch Allergy Immunol. 2021;182:277. 10.1159/000511146
- de Lacerda LB, Rios WM, Masson AP, Brandão IT, Milani TM, et al. Oral administration of Hsp65-producing Lactococcus lactis attenuates allergic asthma in a murine model. J Appl Microbiol. 2021;130:2075. 10.1111/jam.14913
- Vasiee A, Falah F, Sankian M, Tabatabaei-Yazdi F, Mortazavi SA. Oral Immunotherapy Using Probiotic Ice Cream Containing Recombinant Food-Grade Which Inhibited Allergic Responses in a BALB/c Mouse Model. J Immunol Res. 2020;2020:2635230. 10.1155/2020/2635230
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- Tan Lim CSC, Sajo MEJV, Orteza KEMP, Fernandez PBA, Vila MJC. Next-Gen biotherapeutics: A systematic review and network meta-analysis on postbiotics as treatment for pediatric atopic dermatitis. Pediatr Allergy Immunol. 2023;34:e14022. 10.1111/pai.14022
- Hou Y, Zheng S, Zou F, Wang D, Da H, et al. Lactobacillus rhamnosus 76 alleviates airway inflammation in ovalbumin-allergic mice and improves mucus secretion by down-regulating STAT6/SPDEF pathway. Immunobiology. 2023;228:152712. 10.1016/j.imbio.2023.152712
