Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 56 Researches
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Serving Per Container: 30
Amount Per Serving
%DV
Ultimate Care Probiotic Culture Blend 100 Billion CFU
301 mg
***
Bifido Probiotic BlendBifidobacterium lactis BI-04®, Bifidobacterium lactis HN019™, Bifidobacterium infantis Bi-26™, Bifidobacterium lactis Bi-07®
54 Billion CFU
Lacto Probiotic BlendLactobacillus plantarum Lp-115®, Lactobacillus rhamnosus GG, Lactococcus lactis LI-23™, Lactobacillus casei Lc-11®, Lactobacillus paracasei Lpc-37®, Lactobacillus acidophilus La-14®, Lactobacillus acidophilus NCFM®, Lactobacillus brevis Lbr-35™
46 Billion CFU
Top Medical Research Studies
9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9.5
We explored the effectiveness of a live recombinant Lactococcus lactis vaccine designed to combat enterotoxigenic Escherichia coli, a major cause of diarrhea. The study involved administering the vaccine to mice, who then showed strong immune responses, such as increased antibody production and T cell activation.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
Read More
9
We evaluated the effectiveness of Bifidobacterium lactis XLTG11 in treating acute watery diarrhea in children through a rigorous randomized, double-blind, placebo-controlled trial.
Children who received the probiotic alongside their conventional treatment had significantly shorter diarrhea durations and hospital stays compared to those who only got standard care. Additionally, those taking Bifidobacterium showed better improvement rates and healthier gut microbiomes after treatment.
Overall, this study suggests that Bifidobacterium lactis can be a beneficial adjunct therapy for children suffering from diarrhea.
Children who received the probiotic alongside their conventional treatment had significantly shorter diarrhea durations and hospital stays compared to those who only got standard care. Additionally, those taking Bifidobacterium showed better improvement rates and healthier gut microbiomes after treatment.
Overall, this study suggests that Bifidobacterium lactis can be a beneficial adjunct therapy for children suffering from diarrhea.
Read More
Most Useful Reviews
9
Fast relief
2 people found this helpful
Just try this product. It saved my life. After antibiotics, my stomach was a disaster with bloating, diarrhea, and pain; doctors were of no help. A friend mentioned this probiotic, and within a week of taking it every morning, I felt significantly better. Now I’m fine and take it daily. Everyone I’ve recommended it to has seen great results. I highly encourage anyone with stomach issues to give it a go.
Read More
7.5
Reduced infections
3 people found this helpful
It’s baffling that my aunt’s doctor recommended only more antibiotics without considering alternatives. I bought this product for her because she frequently battled yeast infections and diarrhoea from antibiotic use. It helped her manage these issues considerably, and she has begun to heal. Thankfully, she is on the mend now.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 56 Researches
8
- All Researches
9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.
Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.
This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9.5
We explored the effectiveness of a live recombinant Lactococcus lactis vaccine designed to combat enterotoxigenic Escherichia coli, a major cause of diarrhea. The study involved administering the vaccine to mice, who then showed strong immune responses, such as increased antibody production and T cell activation.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
Read More
9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9.5
We explored the impact of Lactobacillus acidophilus and L. plantarum on patients suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). In a randomized, single-blinded clinical trial of 100 patients, some received standard IBS treatment alone while others added probiotics to their therapy.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
After 12 weeks, both groups saw improvements, but those who took probiotics reported significantly better outcomes. Patients using probiotics experienced greater reductions in IBS symptoms, achieving near complete relief, while some on standard treatment still faced moderate symptoms. This suggests probiotics could enhance IBS management.
Read More
9
We aimed to understand how a mix of probiotics called Sensi-Biome affects diarrhea triggered by gut imbalances. In our study, this probiotic blend was tested on rats suffering from acid-induced diarrhea.
We observed improved stool moisture, intestinal movement, and overall gut health, specifically in one of the dosage groups. Notably, the probiotics also helped balance serotonin levels and reduced inflammation.
This shows that Sensi-Biome can indeed help manage diarrhea by impacting gut health and related metabolic pathways.
We observed improved stool moisture, intestinal movement, and overall gut health, specifically in one of the dosage groups. Notably, the probiotics also helped balance serotonin levels and reduced inflammation.
This shows that Sensi-Biome can indeed help manage diarrhea by impacting gut health and related metabolic pathways.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Fast relief
2 people found this helpful
Just try this product. It saved my life. After antibiotics, my stomach was a disaster with bloating, diarrhea, and pain; doctors were of no help. A friend mentioned this probiotic, and within a week of taking it every morning, I felt significantly better. Now I’m fine and take it daily. Everyone I’ve recommended it to has seen great results. I highly encourage anyone with stomach issues to give it a go.
Read More
7.5
Reduced infections
3 people found this helpful
It’s baffling that my aunt’s doctor recommended only more antibiotics without considering alternatives. I bought this product for her because she frequently battled yeast infections and diarrhoea from antibiotic use. It helped her manage these issues considerably, and she has begun to heal. Thankfully, she is on the mend now.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
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- Jeong JJ, Jin YJ, Ganesan R, Park HJ, Min BH, et al. Multistrain Probiotics Alleviate Diarrhea by Modulating Microbiome-Derived Metabolites and Serotonin Pathway. Probiotics Antimicrob Proteins. 2024. 10.1007/s12602-024-10232-4
- Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study. Eur J Clin Nutr. 2024;78:501. 10.1038/s41430-024-01428-6
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- Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjunctive efficacy of Lactis XLTG11 for Acute diarrhea in children: A randomized, blinded, placebo-controlled study. Nutrition. 2023;111:112052. 10.1016/j.nut.2023.112052
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- Cai X, Yi P, Chen X, Wu J, Lan G, et al. Intake of compound probiotics accelerates the construction of immune function and gut microbiome in Holstein calves. Microbiol Spectr. 2024;12:e0190923. 10.1128/spectrum.01909-23
- Yu J, Fu J, Liu H, Kang C, Wang Z, et al. Application of Recombinant Lactic Acid Bacteria (LAB) Live Vector Oral Vaccine in the Prevention of F4+ Enterotoxigenic . Vaccines (Basel). 2024;12. 10.3390/vaccines12030304
- Jaramillo-Jaramillo AS, Blanvillain-Rivera V, Coulson TJD, Farzan V, Friendship R, et al. Effect of a culture supernatant on diarrhea and performance parameters of piglets in the post-weaning period and on expression of the gene . Can Vet J. 2024;65:259.
- Shin SY, Park S, Moon JM, Kim K, Kim JW, et al. Compositional Changes in the Gut Microbiota of Responders and Non-responders to Probiotic Treatment Among Patients With Diarrhea-predominant Irritable Bowel Syndrome: A Post Hoc Analysis of a Randomized Clinical Trial. J Neurogastroenterol Motil. 2022;28:642. 10.5056/jnm21202
- Thu NN, Mai TT, Trang TTT, Tuan NA, Quyen TC, et al. Impact of Infectious Disease after Strain Plasma Intake in Vietnamese Schoolchildren: A Randomized, Placebo-Controlled, Double-Blind Study. Nutrients. 2022;14. 10.3390/nu14030552
- Ahmadi Rouzbahani H, Mousavi Gargari SL, Nazarian S, Abdollahi S. Protective Immunity Against Enterotoxigenic Escherichia coli by Oral Vaccination of Engineered Lactococcus lactis. Curr Microbiol. 2021;78:3464. 10.1007/s00284-021-02601-x
- Zhang K, Mirza WA, Ni P, Yu M, Wang C, et al. Recombination Lactococcus lactis expressing Helicobacter pylori neutrophil-activating protein A attenuates food allergy symptoms in mice. FEMS Microbiol Lett. 2021;368. 10.1093/femsle/fnab034
- Song J, Zhao L, Song M. A Lactococcus lactis-vectored oral vaccine induces protective immunity of mice against enterotoxigenic Escherichia coli lethal challenge. Immunol Lett. 2020;225:57. 10.1016/j.imlet.2020.06.007
- Wang J, Tian M, Li W, Hao F. Preventative delivery of IL-35 by Lactococcus lactis ameliorates DSS-induced colitis in mice. Appl Microbiol Biotechnol. 2019;103:7931. 10.1007/s00253-019-10094-9
- Lay CL, Dridi L, Bergeron MG, Ouellette M, Fliss IL. Nisin is an effective inhibitor of Clostridium difficile vegetative cells and spore germination. J Med Microbiol. 2016;65:169. 10.1099/jmm.0.000202
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- Chorawala MR, Chauhan S, Patel R, Shah G. Cell Wall Contents of Probiotics (Lactobacillus species) Protect Against Lipopolysaccharide (LPS)-Induced Murine Colitis by Limiting Immuno-inflammation and Oxidative Stress. Probiotics Antimicrob Proteins. 2021;13:1005. 10.1007/s12602-020-09738-4
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- Abdulah DM, Sulaiman SJ, Ahmed ZW. Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial. Clin Exp Pediatr. 2024;67:203. 10.3345/cep.2023.01340
- Waitzberg D, Guarner F, Hojsak I, Ianiro G, Polk DB, et al. Can the Evidence-Based Use of Probiotics (Notably Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG) Mitigate the Clinical Effects of Antibiotic-Associated Dysbiosis?. Adv Ther. 2024;41:901. 10.1007/s12325-024-02783-3
- Saviano A, Petruzziello C, Cancro C, Macerola N, Petti A, et al. The Efficacy of a Mix of Probiotics ( LMG P-27481 and GG ATCC 53103) in Preventing Antibiotic-Associated Diarrhea and Infection in Hospitalized Patients: Single-Center, Open-Label, Randomized Trial. Microorganisms. 2024;12. 10.3390/microorganisms12010198
- Poeta M, Cioffi V, Tarallo A, Damiano C, Lo Vecchio A, et al. Postbiotic Preparation of against Diarrhea and Oxidative Stress Induced by Spike Protein of SARS-CoV-2 in Human Enterocytes. Antioxidants (Basel). 2023;12. 10.3390/antiox12101878
- Mego M, Danis R, Chovanec J, Jurisova S, Bystricky B, et al. Randomized double-blind, placebo-controlled multicenter phase III study of prevention of irinotecan-induced diarrhea by a probiotic mixture containing Bifidobacterium BB-12 LGG in colorectal cancer patients. Front Oncol. 2023;13:1168654. 10.3389/fonc.2023.1168654
- Yang Q, Hu Z, Lei Y, Li X, Xu C, et al. Overview of systematic reviews of probiotics in the prevention and treatment of antibiotic-associated diarrhea in children. Front Pharmacol. 2023;14:1153070. 10.3389/fphar.2023.1153070
- Niu H, Zhou X, Liu P, Wu Y, Lyu L, et al. Lactobacillus rhamnosus MN-431 Metabolic Tryptophan Alleviates Complementary Food-Induced Diarrhea through PXR-NF-κB Pathway and AHR-Th17 Cell Response Pathways. Mol Nutr Food Res. 2023;67:e2200530. 10.1002/mnfr.202200530
- Li J, Li Q, Wu Q, Gao N, Wang Z, et al. Exopolysaccharides of Lactobacillus rhamnosus GG ameliorate Salmonella typhimurium-induced intestinal inflammation via the TLR4/NF-κB/MAPK pathway. J Anim Sci Biotechnol. 2023;14:23. 10.1186/s40104-023-00830-7
