Last update
5/21/2026

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.9
USERS' SCORE
Good
Based on 8 Reviews
8.4
Supplement Facts
Serving Size:  1 Capsule
Amount Per Serving
%DV
Women's Care Probiotic Blend
50 Billion CFU 222 mg
***
Bifido Probiotic BlendBifidobacterium lactis BI-04®, Bifidobacterium lactis DSM 15954, Bifidobacterium infantis Bi-26™
26 Billion CFU
 
Lacto Probiotic BlendLactobacillus reuteri RC-14®, Lactobacillus plantarum Lp-115®, Lactobacillus rhamnosus GG, Lactobacillus rhamnosus GR-1®, Lactococcus lactis LI-23™, Lactobacillus casei Lc-11®, Lactobacillus paracasei Lpc-37®, Lactobacillus acidophilus La-14®, Lactobacillus brevis Lbr-35™
24 Billion CFU
 
📅 Last updated:

Top Medical Research Studies

9
Lactobacillus shows promise against flu
We explored the effects of heat-killed Lactobacillus gasseri TMC0356 on mice infected with the flu virus. After 19 days of treatment, we observed improved clinical symptoms, reduced viral loads, and enhanced immune responses in the treated mice compared to controls. This suggests that Lactobacillus could bolster both gut and respiratory immunity against influenza. However, these exciting results are limited to animal studies, and further research in humans is needed to fully understand its benefits.
Read More
8
Probiotic shows promise in RTI
We explored the impact of the probiotic Bifidobacterium lactis Probio-M8 on young children hospitalized for acute respiratory infections.

Sixty children received the probiotic, while another sixty received a placebo under a carefully controlled, double-blind setup.

The study suggested that this probiotic could be a natural way to manage respiratory infections, potentially reducing antibiotic use and hospitalization duration.

However, results indicate that further research is needed to solidify these benefits.
Read More
8
Probiotics enhance immune response safety
We examined how probiotics affect our immune system and their potential to reduce the incidence of flu-like symptoms. In a carefully controlled, double-blind trial, adult participants who frequently caught colds were given either a probiotic drink or a placebo for 12 weeks.

The results showed that those consuming probiotics experienced fewer upper respiratory infections and flu-like symptoms. They also displayed higher immune markers in their blood and gut. While probiotics proved effective overall, no significant differences were noted for other immune-related markers.

This highlights the potential of probiotics as a safe way to combat the common cold and flu.
Read More

Most Useful Reviews

9
Rapid relief from yeast infections
37 people found this helpful
I started to feel normal within three days. I am 31 years old and have suffered from chronic yeast infections for about five years. I used to experience one each month, leading to discomfort during intercourse. I tried various remedies, but these actually work! I could tell a difference within three days. I no longer feel sensitive, and intercourse improved significantly. I have been monitoring my vaginal pH at home and it improved from 7 to 5 in a week. Though it's true that these are somewhat expensive, they are a two-month supply; technically costing $22 a month, unlike others that offer far less value. If you struggle with chronic yeast infections, I strongly suggest you try these.
Read More
9
Excellent yeast infection relief
24 people found this helpful
AMAZING! If you are suffering from chronic yeast infections due to a hormone imbalance or other issues, this is, without a doubt, the best product on the market and it has worked wonders for me. A few years back, I had my first yeast infection and tried using over-the-counter medication by Monistat, which was not only costly but burnt and didn't work at all. I ended up going to the doctor for an exam and receiving several prescriptions, however, there was no improvement. Frustrated with the medical costs, I turned to the internet and discovered that many women had found relief through probiotics. Although this one is a bit pricey, it is the one that has worked best for me, and I often recommend it to other women who suffer as I did.
Read More
9
Natural yeast infection remedy
14 people found this helpful
YES, these work for managing recurrent yeast infections! If you're seeking a natural treatment, this is the solution. I have been dealing with hormonally related yeast overgrowth for some time now, and as my cycle approaches, it worsens. After starting Ultimate Flora Women's, things appeared normal again within three days. Continuing to take them regularly has prevented the problem's return. If you need an immediate solution, I suggest finding probiotics at your local pharmacy and using one as a vaginal suppository; it can resolve issues quickly.
Read More

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Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.9
  • All Researches
We examined the impact of EpiCor, a yeast-derived postbiotic, on flu symptoms in healthy children. In a study involving 256 kids aged 4-12, participants took either EpiCor or a placebo for 84 days during the flu season.

The results were promising! Kids receiving EpiCor experienced significantly reduced severity of cold/flu symptoms and relied less on cold medications compared to those on the placebo. Overall, EpiCor proved to be a safe option for bolstering immune function in young children.
Read More
9
Probiotics reduce flu symptoms
We conducted a study to see if probiotics could make a difference for flu-vaccinated elderly individuals. Fifty participants in a double-blind, placebo-controlled trial took a multistrain probiotic for 28 days.

After this period, we noticed a decrease in both symptoms and incidence of common infections in those who received the probiotics. Additionally, we found promising changes in immune system markers and gut health. This indicates that probiotics might improve protection against infections by boosting immunity and positively influencing gut microbiota.
Read More
We explored how probiotics can reduce the health care costs and societal impacts of flu-like respiratory infections. By using a state-transition microsimulation model, we investigated various scenarios to estimate the economic benefits of probiotics in 2017-2018.

Our findings revealed potential savings of $4.6 million to $1.4 billion, depending on the source of data analyzed. Overall, fewer RTI episodes led to less medical intervention and fewer missed workdays.

While the results suggest probiotics could alleviate some burden on health systems, this study focuses mainly on economic modeling rather than direct clinical effectiveness.
Read More
9
Probiotics show promise against influenza
We investigated the potential of two recombinant probiotics, Lactobacillus plantarum NC8-409-1 and NC8-409-2, in preventing influenza in mice. These vaccines successfully triggered immune responses, notably increasing specific antibodies in both the intestine and serum.

Notably, NC8-409-2 demonstrated substantial protection against H9N2—up to 80%—while NC8-409-1 showed about 60% protection against H1N1. Although these results hint at exciting possibilities for developing oral vaccines against avian flu, the overall effectiveness against human flu is uncertain.
Read More
9
Lactobacillus shows promise against flu
We explored the effects of heat-killed Lactobacillus gasseri TMC0356 on mice infected with the flu virus. After 19 days of treatment, we observed improved clinical symptoms, reduced viral loads, and enhanced immune responses in the treated mice compared to controls. This suggests that Lactobacillus could bolster both gut and respiratory immunity against influenza. However, these exciting results are limited to animal studies, and further research in humans is needed to fully understand its benefits.
Read More

User Reviews

USERS' SCORE
Good
Based on 8 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Rapid relief from yeast infections
37 people found this helpful
I started to feel normal within three days. I am 31 years old and have suffered from chronic yeast infections for about five years. I used to experience one each month, leading to discomfort during intercourse. I tried various remedies, but these actually work! I could tell a difference within three days. I no longer feel sensitive, and intercourse improved significantly. I have been monitoring my vaginal pH at home and it improved from 7 to 5 in a week. Though it's true that these are somewhat expensive, they are a two-month supply; technically costing $22 a month, unlike others that offer far less value. If you struggle with chronic yeast infections, I strongly suggest you try these.
Read More
9
Excellent yeast infection relief
24 people found this helpful
AMAZING! If you are suffering from chronic yeast infections due to a hormone imbalance or other issues, this is, without a doubt, the best product on the market and it has worked wonders for me. A few years back, I had my first yeast infection and tried using over-the-counter medication by Monistat, which was not only costly but burnt and didn't work at all. I ended up going to the doctor for an exam and receiving several prescriptions, however, there was no improvement. Frustrated with the medical costs, I turned to the internet and discovered that many women had found relief through probiotics. Although this one is a bit pricey, it is the one that has worked best for me, and I often recommend it to other women who suffer as I did.
Read More
9
Natural yeast infection remedy
14 people found this helpful
YES, these work for managing recurrent yeast infections! If you're seeking a natural treatment, this is the solution. I have been dealing with hormonally related yeast overgrowth for some time now, and as my cycle approaches, it worsens. After starting Ultimate Flora Women's, things appeared normal again within three days. Continuing to take them regularly has prevented the problem's return. If you need an immediate solution, I suggest finding probiotics at your local pharmacy and using one as a vaginal suppository; it can resolve issues quickly.
Read More
9
Gentle on stomach
4 people found this helpful
Phenomenal product!! Ultimate Flora Vaginal Support 50 Billion - 60 - Veg Cap. I originally purchased this at a Health Food Store for £59.00 for 30 tablets. I was misled to think it was the cheapest; I bought a 2-month supply for £55.24 with free shipping, arriving in four days! I've been on two antibiotics for about six months and have only had two yeast infections cleared with Diflucan. My vaginal health was poor prior to this product, but I'd recommend it to anyone allergic to dairy, soy, or whey. It's a vegetable capsule, very gentle on the stomach! I'll definitely reorder this product.
Read More
7.5
Tremendous relief
4 people found this helpful
Helps relieve my IC. I read somewhere that probiotics can assist with interstitial cystitis. Dealing with a particularly nasty flare-up had me desperate enough to seek help. A clerk recommended this brand for vaginal support. Relief began after the first day. I thought it was a fluke, but it truly helped me immensely! I still take CystoProtek and Prelief, but I've not had a flare-up since starting Ultimate Flora. One pill a day has significantly improved my quality of life and is also £10 cheaper than the health food store.
Read More

Frequently Asked Questions

We examined how Lactobacillus acidophilus could help reduce cold and flu-like symptoms in young children during the winter months. In this well-structured study, 326 children aged 3 to 5 participated. They were randomly assigned to one of three groups: one received a placebo, while the others were given either Lactobacillus acidophilus alone or in combination with another probiotic, Bifidobacterium animalis subsp lactis.

Over a period of six months, the children in both probiotic groups reported significantly fewer symptoms and shorter durations of ailments compared to those on the placebo. For instance, the incidence of fever dropped by 53% to 73%, while coughing and rhinorrhea (a runny nose) also saw impressive reductions. Children taking probiotics needed antibiotics much less often and missed fewer days of childcare due to illness.

Overall, this study suggests that incorporating daily Lactobacillus acidophilus into children's diets can be an effective approach to bolster their health during flu season. It shows promise as a safe and helpful way to reduce common winter illnesses in young kids.

References

  1. Al-Akel FC, Chiperi LE, Eszter VK, Bacârea A. Role as a Probiotic in Children's Health and Disease Prophylaxis-A Systematic Review. Life (Basel). 2024;14. 10.3390/life14121613
  2. Singh RG, Garcia-Campayo V, Green JB, Paton N, Saunders JD, et al. Efficacy of a yeast postbiotic on cold/flu symptoms in healthy children: A randomized-controlled trial. Pediatr Res. 2024;96:1739. 10.1038/s41390-024-03331-z
  3. Zhao Y, Dong BR, Hao Q. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. 2022;8:CD006895. 10.1002/14651858.CD006895.pub4
  4. Sandionigi A, De Giani A, Tursi F, Michelotti A, Cestone E, et al. Effectiveness of Multistrain Probiotic Formulation on Common Infectious Disease Symptoms and Gut Microbiota Modulation in Flu-Vaccinated Healthy Elderly Subjects. Biomed Res Int. 2022;2022:3860896. 10.1155/2022/3860896
  5. Mageswary MU, Ang XY, Lee BK, Chung YF, Azhar SNA, et al. Probiotic Bifidobacterium lactis Probio-M8 treated and prevented acute RTI, reduced antibiotic use and hospital stay in hospitalized young children: a randomized, double-blind, placebo-controlled study. Eur J Nutr. 2022;61:1679. 10.1007/s00394-021-02689-8
  6. Lenoir-Wijnkoop I, Merenstein D, Korchagina D, Broholm C, Sanders ME, et al. Probiotics Reduce Health Care Cost and Societal Impact of Flu-Like Respiratory Tract Infections in the USA: An Economic Modeling Study. Front Pharmacol. 2019;10:980. 10.3389/fphar.2019.00980
  7. Bo F, Yang WT, Shonyela SM, Jin YB, Huang KY, et al. Immune responses of mice inoculated with recombinant Lactobacillus plantarum NC8 expressing the fusion gene HA2 and 3M2e of the influenza virus and protection against different subtypes of influenza virus. Virus Res. 2019;263:64. 10.1016/j.virusres.2019.01.001
  8. Zhang H, Yeh C, Jin Z, Ding L, Liu BY, et al. Prospective study of probiotic supplementation results in immune stimulation and improvement of upper respiratory infection rate. Synth Syst Biotechnol. 2018;3:113. 10.1016/j.synbio.2018.03.001
  9. Belkacem N, Bourdet-Sicard R, Taha MK. Lactobacillus paracasei feeding improves the control of secondary experimental meningococcal infection in flu-infected mice. BMC Infect Dis. 2018;18:167. 10.1186/s12879-018-3086-9
  10. Belkacem N, Serafini N, Wheeler R, Derrien M, Boucinha L, et al. Lactobacillus paracasei feeding improves immune control of influenza infection in mice. PLoS One. 2017;12:e0184976. 10.1371/journal.pone.0184976
  11. Di Pierro F, Colombo M, Zanvit A, Rottoli AS. Positive clinical outcomes derived from using K12 to prevent streptococcal pharyngotonsillitis in children: a pilot investigation. Drug Healthc Patient Saf. 2016;8:77. PubMed
  12. Meng H, Lee Y, Ba Z, Peng J, Lin J, et al. Consumption of Bifidobacterium animalis subsp. lactis BB-12 impacts upper respiratory tract infection and the function of NK and T cells in healthy adults. Mol Nutr Food Res. 2016;60:1161. 10.1002/mnfr.201500665
  13. Lenoir-Wijnkoop I, Gerlier L, Bresson JL, Le Pen C, Berdeaux G. Public health and budget impact of probiotics on common respiratory tract infections: a modelling study. PLoS One. 2015;10:e0122765. 10.1371/journal.pone.0122765
  14. Langkamp-Henken B, Rowe CC, Ford AL, Christman MC, Nieves C, et al. Bifidobacterium bifidum R0071 results in a greater proportion of healthy days and a lower percentage of academically stressed students reporting a day of cold/flu: a randomised, double-blind, placebo-controlled study. Br J Nutr. 2015;113:426. 10.1017/S0007114514003997
  15. Kawase M, He F, Kubota A, Yoda K, Miyazawa K, et al. Heat-killed Lactobacillus gasseri TMC0356 protects mice against influenza virus infection by stimulating gut and respiratory immune responses. FEMS Immunol Med Microbiol. 2012;64:280. 10.1111/j.1574-695X.2011.00903.x
  16. Bieuvelet S, Seyrig C, Leclerc C. [A preliminary survey on the interest of eating probiotics, cypress and echinacea to prevent the apparition of winter infections]. Phytotherapie (Paris). 2011;9:120. 10.1007/s10298-011-0613-x
  17. Leyer GJ, Li S, Mubasher ME, Reifer C, Ouwehand AC. Probiotic effects on cold and influenza-like symptom incidence and duration in children. Pediatrics. 2009;124:e172. 10.1542/peds.2008-2666
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