Research Authors

Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
USERS' SCORE
Good
Based on 5 Reviews
8.4
Supplement Facts
Serving Size: 2 VegCaps
Serving Per Container: 125
Amount Per Serving
%DV
Vitamin C (As ascorbic Acid, Rose Hips, Acerola Cherry)
1,000 mg
1,111%
Bioflavonoid Concentrate (From Lemon)
500 mg
*
Rutin Concentrate
100 mg
*
Hesperidin Concentrate
100 mg
*
Citrus Pectin
30 mg
*

Top Medical Research Studies

We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.

We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.

This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.

Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.

This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More

Most Useful Reviews

9
Reflux relief
This vitamin C doesn't cause me reflux, which has been a welcome change after trying several other options that did.
Read More
9
Acidity management
Amazing technology with a two-stage timed release and calcium and magnesium buffers that help with acidity and reflux!
Read More
7.5
Reflux-friendly
One capsule contains 500 mg of buffered vitamin C, making it suitable for those with reflux or gastric issues. I experience no heartburn or belching. I usually take one daily and two during cold seasons. I recommend this brand.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 2 Researches
7.5
  • All Researches
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.

We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.

This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.
Read More
7
Antioxidants may reduce cancer risk
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.

Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.

This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
Read More

User Reviews

USERS' SCORE
Good
Based on 5 Reviews
8.4
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Reflux relief
This vitamin C doesn't cause me reflux, which has been a welcome change after trying several other options that did.
Read More
9
Acidity management
Amazing technology with a two-stage timed release and calcium and magnesium buffers that help with acidity and reflux!
Read More
7.5
Reflux-friendly
One capsule contains 500 mg of buffered vitamin C, making it suitable for those with reflux or gastric issues. I experience no heartburn or belching. I usually take one daily and two during cold seasons. I recommend this brand.
Read More
7.5
Buffered support
As someone prone to acid reflux, this buffered product is a relief, allowing me to avoid worrying about acidity.
Read More
7.5
Gentle on reflux
The best all-round vitamin C I have tried. Solary Super Bio Vitamin C is buffered and time-released, helping me maintain stable levels of vitamin C without aggravating my reflux. It’s gentle on my stomach and contains bioflavonoids that aid absorption.
Read More

Frequently Asked Questions

9
Reflux relief
This vitamin C doesn't cause me reflux, which has been a welcome change after trying several other options that did.
7.5
Reflux-friendly
One capsule contains 500 mg of buffered vitamin C, making it suitable for those with reflux or gastric issues. I experience no heartburn or belching. I usually take one daily and two during cold seasons. I recommend this brand.
9
Acidity management
Amazing technology with a two-stage timed release and calcium and magnesium buffers that help with acidity and reflux!
7.5
Gentle on reflux
The best all-round vitamin C I have tried. Solary Super Bio Vitamin C is buffered and time-released, helping me maintain stable levels of vitamin C without aggravating my reflux. It’s gentle on my stomach and contains bioflavonoids that aid absorption.
7
Antioxidants may reduce cancer risk
We studied how antioxidants, particularly vitamin C, relate to reflux esophagitis and esophageal adenocarcinoma, aiming to uncover potential protective effects. Through a case-control approach involving groups with reflux esophagitis, Barrett's esophagus, and esophageal adenocarcinoma, we assessed the dietary intake of antioxidants and their relationship with these conditions.

Our findings revealed that a higher overall antioxidant intake was linked to a reduced risk of esophageal adenocarcinoma. Specifically, individuals with the highest vitamin C intake had a significantly lower risk of developing this type of cancer. However, while vitamin C also appeared to reduce the risk of reflux esophagitis, we found no strong connection between vitamin C and Barrett's esophagus, nor with other antioxidants such as vitamin E, carotenoids, zinc, copper, or selenium.

This suggests that while antioxidants could play a role in lowering the risk of esophageal adenocarcinoma, they might be more influential in terms of progression rather than initiating reflux conditions. Overall, our study highlights the potential significance of dietary vitamin C in addressing reflux issues but points out limitations when it comes to other forms of esophageal disorders.
We aimed to understand how Vitamin C could help with the toxicity caused by omeprazole, a common treatment for conditions like gastroesophageal reflux disease (GERD) and gastritis. During our study, we examined gastric cells from rabbits to see how Vitamin C, alongside other antioxidants, could protect these cells from damage caused by omeprazole.

We found that both omeprazole and another thiol-oxidant, monochloramine, significantly reduced cell viability. Interestingly, the toxicity from omeprazole occurred independently from monochloramine. However, we observed that using Vitamin C effectively protected the gastric cells from this injury, maintaining their function without interfering with omeprazole's intended effects.

This suggests that incorporating Vitamin C into treatment plans for people using proton pump inhibitors (PPIs) like omeprazole could be beneficial. Ultimately, our research highlights the potential of using antioxidants to mitigate the adverse effects often associated with medication for reflux and related conditions.

References

  1. Murphy SJ, Anderson LA, Ferguson HR, Johnston BT, Watson PR, et al. Dietary antioxidant and mineral intake in humans is associated with reduced risk of esophageal adenocarcinoma but not reflux esophagitis or Barrett's esophagus. J Nutr. 2010;140:1757. 10.3945/jn.110.124362
  2. Kohler JE, Blass AL, Liu J, Tai K, Soybel DI. Antioxidant pre-treatment prevents omeprazole-induced toxicity in an in vitro model of infectious gastritis. Free Radic Biol Med. 2010;49:786. 10.1016/j.freeradbiomed.2010.05.034
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