We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
Read More
8
Vitamin C triterpene flu inhibitors
Design, synthesis and biological evaluation of novel L-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors.
We recently explored the potential of novel compounds that are combinations of L-ascorbic acid, commonly known as vitamin C, and pentacyclic triterpenes in battling the flu. The study focused on compounds we created and tested against the influenza virus in MDCK cells, particularly looking at their effectiveness and any possible side effects.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Read More
4
Vitamin C shows moderate influenza inhibition
Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus.
We investigated the effects of various compounds, including vitamin C, on the neuraminidase (NA) activity of influenza viruses, specifically H1N1 and H5N2. Neuraminidase is crucial for the virus as it helps release new viral particles from infected cells, making it a key target for antiviral treatments.
In this study, we focused on five different compounds that are structurally distinct from sialic acid, which is the natural substrate of neuraminidase. Among those tested, vitamin C was one of the compounds alongside others like acetyl phenylalanylmethionine and propanoic acid derivatives. We found that these compounds inhibited NA activity, but the degree of inhibition varied.
Notably, the inhibition we observed was in the millimolar range, which suggests that while there is some effect, the affinity of vitamin C to inhibit neuraminidase is moderate compared to the reference drug zanamivir. The IC values for the compounds ranged from 6.4 to 73 mM, indicating that they are not as potent as zanamivir.
Overall, our study presents vitamin C and other small organic molecules as potential lead compounds for developing new neuraminidase inhibitors, even if vitamin C’s impact on flu remains to be clarified as part of a broader analysis of multiple compounds.
Read More
Most Useful Reviews
9
Effective dosage
7 people found this helpful
No colds or flu so far since taking this. We take about 3000 mg per day and have avoided any illness, even around snotty-nosed grandkids. Building your immune system is key, and Vitamin C is essential.
Read More
9
Prevented flu effectively
2 people found this helpful
I've taken one tablet of California Gold C 1,000 mg for breakfast and one before bed for years. I believe 2,000 mg per day is ideal for this powerful antioxidant. It forms the core of my immune system strategy, alongside B-Complex, Vitamins D and E, Melatonin, Zinc, and Quercetin. It works for me; at 72, I haven't caught the flu in 15 years. Excellent value for money.
Read More
10
Stops symptoms
I take it when I sense the flu or cold is starting, and it alleviates everything before it begins!!! Like, please. 👍
We set out to discover how red ginseng and vitamin C work together to enhance immune cell function and fight off viral infections like the flu. In our investigation, we treated human immune cells and specific types of mice unable to produce vitamin C, looking closely at their reaction to influenza A virus/H1N1.
Our findings were quite promising. We observed that both red ginseng and vitamin C elevated the activation levels of immune cells, particularly T-cells and natural killer (NK) cells, known for their vital role in combating viruses. This combination not only helped boost immune cell activity but also reduced lung inflammation caused by the influenza virus, which is crucial for better survival rates during infections.
In cases where vitamin C levels were low in a specific mouse model, we noted that the added nutrients significantly improved their condition. They experienced reduced viral load and inflammation in their lungs after receiving red ginseng and vitamin C, compared to those without this supplementation. These insights suggest that while red ginseng and vitamin C collectively support immune health, the interplay of these substances can be crucial in managing flu infections effectively.
Read More
8
Vitamin C triterpene flu inhibitors
Design, synthesis and biological evaluation of novel L-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors.
We recently explored the potential of novel compounds that are combinations of L-ascorbic acid, commonly known as vitamin C, and pentacyclic triterpenes in battling the flu. The study focused on compounds we created and tested against the influenza virus in MDCK cells, particularly looking at their effectiveness and any possible side effects.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
Read More
8
Vitamin C mitigates flu pneumonia
A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice.
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
Read More
7
Vitamin C's promise against flu
Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
We examined how vitamin C supplementation can impact flu incidence and symptom duration. Our analysis of clinical studies indicated that vitamin C does show promise in reducing the risk of acute respiratory infections, including flu. Specifically, vitamin C reduced the likelihood of catching an acute respiratory infection by approximately 4% (risk ratio of 0.96).
Additionally, we observed that vitamin C also helps shorten the duration of flu symptoms by around 9%. This effect seemed to be more pronounced in men and people from middle-income countries, highlighting the complexity of health factors influenced by gender and socio-economic status.
Overall, while the findings suggest vitamin C can be a modicum of hope in managing flu symptoms, it isn't a standalone solution. Our results advocate for more research to fully understand the impact of vitamin C, especially in the context of the ongoing challenges posed by various respiratory viruses, including influenza.
Read More
4
Vitamin C shows moderate influenza inhibition
Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus.
We investigated the effects of various compounds, including vitamin C, on the neuraminidase (NA) activity of influenza viruses, specifically H1N1 and H5N2. Neuraminidase is crucial for the virus as it helps release new viral particles from infected cells, making it a key target for antiviral treatments.
In this study, we focused on five different compounds that are structurally distinct from sialic acid, which is the natural substrate of neuraminidase. Among those tested, vitamin C was one of the compounds alongside others like acetyl phenylalanylmethionine and propanoic acid derivatives. We found that these compounds inhibited NA activity, but the degree of inhibition varied.
Notably, the inhibition we observed was in the millimolar range, which suggests that while there is some effect, the affinity of vitamin C to inhibit neuraminidase is moderate compared to the reference drug zanamivir. The IC values for the compounds ranged from 6.4 to 73 mM, indicating that they are not as potent as zanamivir.
Overall, our study presents vitamin C and other small organic molecules as potential lead compounds for developing new neuraminidase inhibitors, even if vitamin C’s impact on flu remains to be clarified as part of a broader analysis of multiple compounds.
Read More
User Reviews
USERS' SCORE
Good
Based on 43 Reviews
8.1
All Reviews
Positive Reviews
Negative Reviews
9
Effective dosage
7 people found this helpful
No colds or flu so far since taking this. We take about 3000 mg per day and have avoided any illness, even around snotty-nosed grandkids. Building your immune system is key, and Vitamin C is essential.
Read More
9
Prevented flu effectively
2 people found this helpful
I've taken one tablet of California Gold C 1,000 mg for breakfast and one before bed for years. I believe 2,000 mg per day is ideal for this powerful antioxidant. It forms the core of my immune system strategy, alongside B-Complex, Vitamins D and E, Melatonin, Zinc, and Quercetin. It works for me; at 72, I haven't caught the flu in 15 years. Excellent value for money.
Read More
10
Stops symptoms
I take it when I sense the flu or cold is starting, and it alleviates everything before it begins!!! Like, please. 👍
Read More
9
Boosted immunity significantly
Solaray's Timed Release Vitamin C with Rose Hips & Acerola has become essential to my health regime. The 250 VegCaps come in sturdy packaging. I was pleasantly surprised by the ease of swallowing the capsules. Since taking them, I have noticed a boost in energy, fewer colds, and improved skin health. Compared to other supplements, it is affordable and offers a 100-day supply. This supplement has become vital to my daily routine. I highly recommend it for supporting immune function and overall wellness.
Read More
9
Prevented colds entirely
I appreciate the time-release feature of this essential supplement. With 1,000 mg of vitamin C in one capsule, I have not had a cold, coronavirus, or influenza. It has genuinely been beneficial; health is paramount.
The flu, short for influenza, is a contagious respiratory illness caused by influenza viruses. It affects the nose, throat, and sometimes the lungs, leading to a range of symptoms that can vary in severity. Common symptoms include fever, chills, muscle aches, cough, congestion, runny nose, headaches, and fatigue. The flu can lead to serious complications, particularly in vulnerable populations such as young children, the elderly, pregnant women, and those with underlying health conditions.
The flu virus spreads primarily through respiratory droplets when an infected person coughs, sneezes, or talks. It can also be transmitted by touching surfaces contaminated with the virus and then touching one's face. Vaccination is the most effective way to prevent the flu, and the vaccine is typically updated annually to provide protection against the most common circulating strains. In addition to vaccination, practicing good hygiene, such as frequent handwashing and respiratory etiquette, can help minimize the risk of infection.
Vitamin C, also known as ascorbic acid, is a water-soluble vitamin that plays a critical role in numerous bodily functions. As an essential nutrient, it contributes to the growth and repair of tissues in the body, and it is vital for the production of collagen, an important protein that helps maintain skin, cartilage, tendons, ligaments, and blood vessels. Additionally, Vitamin C acts as a powerful antioxidant, which means it helps combat free radicals—unstable molecules that can cause oxidative stress and contribute to various chronic diseases.
Moreover, Vitamin C enhances iron absorption from plant-based foods, making it a vital component for those following vegetarian or vegan diets. While many people get sufficient Vitamin C from a well-balanced diet that includes fruits and vegetables like oranges, strawberries, kiwi, broccoli, and bell peppers, some individuals might require supplementation. It's generally recommended to stay within the daily intake guidelines, as excessive consumption can lead to gastrointestinal disturbances. Overall, Vitamin C is not just a skincare celebrity—it's a fundamental part of maintaining overall health and well-being.
Vitamin C is often touted as a remedy for the common cold and flu, but the scientific evidence supporting its effectiveness is mixed. Some studies suggest that taking Vitamin C may reduce the duration and severity of flu-like symptoms, particularly in people who are under physical stress, such as athletes. However, for the average person, the benefits of high-dose Vitamin C in preventing or treating the flu are not conclusively supported by research. It's generally recommended to maintain an adequate intake of Vitamin C as part of a balanced diet, but relying solely on supplements is not a guaranteed method for preventing the flu.
Incorporating Vitamin C-rich foods, such as citrus fruits, strawberries, and bell peppers, can support your immune system and overall health. It's important to note that while Vitamin C can contribute to your well-being, it should not replace conventional flu prevention measures, like vaccination and good hygiene practices. If you're already experiencing flu symptoms, it's advisable to consult with a healthcare professional for appropriate treatment options.
Based on user reviews, the timeline for noticing results after starting a Vitamin C supplement can vary. Some users report feeling relief almost immediately, especially when taken at the first sign of flu symptoms, as one reviewer mentioned it alleviates everything before it begins Read Review. A consistent regimen of Vitamin C seems to contribute to enhanced immunity, leading others to note they haven't suffered from flu symptoms at all or found their recovery time significantly reduced after a mild illness Read Review.
Many users emphasize the importance of regular intake. For example, one user preferred taking the supplement daily to build up their resistance, stating they haven’t caught the flu in years Read Review. Overall, while some feel immediate effects and others see benefits over time, the general consensus among users is that consistent use of Vitamin C is key to maximizing its effectiveness against flu and cold symptoms.
Vitamin C has garnered attention in scientific research for its potential role in alleviating flu symptoms and enhancing immune response. A comprehensive review indicated that vitamin C supplementation may reduce the incidence of acute respiratory infections, including the flu, by approximately 4% and shorten the duration of flu symptoms by about 9% [1]. Furthermore, when combined with other compounds, vitamin C may exhibit enhanced efficacy against the influenza virus. For example, studies suggest that vitamin C-conjugated triterpenes demonstrate significant antiviral activity, inhibiting the virus's ability to attach to cells [4].
Moreover, research has shown that vitamin C can bolster immune cell function, reducing lung inflammation in the context of flu infections [3]. It has also been found to protect against severe pneumonia caused by the H1N1 strain, particularly in stressed environments, by modulating immune response genes [5]. While these findings highlight the multifaceted benefits of vitamin C in managing flu-related health issues, it is important to note that it should not be viewed as a standalone solution but rather as part of a broader approach to flu prevention and treatment.
Users report a range of improvements in their symptoms and overall health after incorporating Vitamin C supplements into their routines. Many individuals attribute the reduction or complete absence of cold and flu symptoms to their consistent use of Vitamin C. For example, one user noted they haven't caught the flu in 15 years, crediting this to their daily intake of 2,000 mg Read Review. Others have emphasized that taking Vitamin C at the onset of cold symptoms can alleviate issues before they escalate Read Review.
A number of users have reported improvements beyond just the prevention of illness. Several mention increased energy levels and general wellness, with one individual commenting on clearer skin, fewer colds, and improved immune function since including Vitamin C in their regimen Read Review. The consensus among users suggests that regular intake not only protects against illnesses but may also enhance recovery times, highlighting the importance of making Vitamin C a staple in daily health strategies Read Review. Nevertheless, it's worth noting that individual results may vary, and what works for one person may not yield the same results for another.
Users report positive experiences when combining Vitamin C supplements with other products aimed at bolstering immunity and preventing flu. For instance, one long-time user mentioned including B-Complex, Vitamins D and E, Melatonin, Zinc, and Quercetin along with their Vitamin C routine, asserting that this combination has kept them flu-free for 15 years Read Review. Another user highlighted the benefits of taking Vitamin C at the first sign of illness to enhance effectiveness, suggesting that it alleviates symptoms before they escalate when paired with preventative measures Read Review.
Several reviews indicate that regular Vitamin C intake, especially in combination with other immune-supportive supplements, enhances overall health and reduces the susceptibility to illnesses like the flu. Users noted a significant reduction in flu and cold symptoms, attributing their success to consistent use alongside their Vitamin C routine Read ReviewRead Review. While many specifically advocate for Vitamin C as a go-to in their preventative arsenal, the consensus among users suggests that a holistic approach, incorporating multiple supplements, yields the best results in maintaining immune health and preventing flu symptoms.
The optimal dose of Vitamin C for treating flu symptoms is not definitively established, but research indicates significant benefits at higher doses. One study highlighted that administering oral vitamin C at doses of 125 and 250 mg/kg to stressed mice resulted in marked reduction of severe pneumonia outcomes caused by the H1N1 strain of the influenza virus [5]. While this dosage was effective in an animal model, translating these findings to humans suggests that similar higher doses could potentially yield beneficial effects.
Another analysis established that Vitamin C supplementation may shorten the duration of flu symptoms by around 9% and could reduce the incidence of acute respiratory infections, indicating some prophylactic benefit [1]. However, it's important to note that while Vitamin C can support immune function and potentially alleviate some flu symptoms, it should not replace other recommended treatments or preventive measures during flu season. The overall evidence supports ongoing research to clarify the most effective dosing strategies in the human population.
10
Stops symptoms
I take it when I sense the flu or cold is starting, and it alleviates everything before it begins!!! Like, please. 👍
7.5
Speeds recovery
Great product at affordable prices! I've been taking this time-release vitamin C and found it aids in recovering sooner from mild flu or cold. My whole family takes it as added protection too. 👍🏼
9
Winter coverage
Excellent vitamin C! The whole family has been using it for a month now. We have almost passed the winter without colds and flu. The package is large, sufficient for a long time, and I am very satisfied!
9
Prevented flu effectively
2 people found this helpful
I've taken one tablet of California Gold C 1,000 mg for breakfast and one before bed for years. I believe 2,000 mg per day is ideal for this powerful antioxidant. It forms the core of my immune system strategy, alongside B-Complex, Vitamins D and E, Melatonin, Zinc, and Quercetin. It works for me; at 72, I haven't caught the flu in 15 years. Excellent value for money.
9
Boosted immunity significantly
Solaray's Timed Release Vitamin C with Rose Hips & Acerola has become essential to my health regime. The 250 VegCaps come in sturdy packaging. I was pleasantly surprised by the ease of swallowing the capsules. Since taking them, I have noticed a boost in energy, fewer colds, and improved skin health. Compared to other supplements, it is affordable and offers a 100-day supply. This supplement has become vital to my daily routine. I highly recommend it for supporting immune function and overall wellness.
9
Easy on stomach
Good quality ingredients with 1000mg of Vitamin C. Easier on the stomach than dissolvable tablets. Good for immunity and keeping flu at bay. Highly recommended.
7
Vitamin C's promise against flu
Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis.
We examined how vitamin C supplementation can impact flu incidence and symptom duration. Our analysis of clinical studies indicated that vitamin C does show promise in reducing the risk of acute respiratory infections, including flu. Specifically, vitamin C reduced the likelihood of catching an acute respiratory infection by approximately 4% (risk ratio of 0.96).
Additionally, we observed that vitamin C also helps shorten the duration of flu symptoms by around 9%. This effect seemed to be more pronounced in men and people from middle-income countries, highlighting the complexity of health factors influenced by gender and socio-economic status.
Overall, while the findings suggest vitamin C can be a modicum of hope in managing flu symptoms, it isn't a standalone solution. Our results advocate for more research to fully understand the impact of vitamin C, especially in the context of the ongoing challenges posed by various respiratory viruses, including influenza.
8
Vitamin C triterpene flu inhibitors
Design, synthesis and biological evaluation of novel L-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors.
We recently explored the potential of novel compounds that are combinations of L-ascorbic acid, commonly known as vitamin C, and pentacyclic triterpenes in battling the flu. The study focused on compounds we created and tested against the influenza virus in MDCK cells, particularly looking at their effectiveness and any possible side effects.
Among all the compounds we evaluated, one stood out: the 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid-betulinic acid conjugate. It displayed significant anti-influenza activity with an effective concentration (EC50) of just 8.7 μM and was not toxic to the cells used in our testing. This suggests that combining vitamin C with these triterpenes might enhance their ability to fight the flu virus, marking an exciting avenue for further research.
We also discovered that this particular compound acts early in the influenza lifecycle, interfering with the virus's ability to attach to cells. We confirmed this by observing that it inhibited the hemagglutination—a crucial step that allows the virus to spread. Our findings indicate that L-ascorbic acid-conjugated triterpenes hold promise as potential anti-influenza agents, specifically targeting viral entry and enhancing the effectiveness of treatment strategies.
9
Immune booster for flu treatment
Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection.
We set out to discover how red ginseng and vitamin C work together to enhance immune cell function and fight off viral infections like the flu. In our investigation, we treated human immune cells and specific types of mice unable to produce vitamin C, looking closely at their reaction to influenza A virus/H1N1.
Our findings were quite promising. We observed that both red ginseng and vitamin C elevated the activation levels of immune cells, particularly T-cells and natural killer (NK) cells, known for their vital role in combating viruses. This combination not only helped boost immune cell activity but also reduced lung inflammation caused by the influenza virus, which is crucial for better survival rates during infections.
In cases where vitamin C levels were low in a specific mouse model, we noted that the added nutrients significantly improved their condition. They experienced reduced viral load and inflammation in their lungs after receiving red ginseng and vitamin C, compared to those without this supplementation. These insights suggest that while red ginseng and vitamin C collectively support immune health, the interplay of these substances can be crucial in managing flu infections effectively.
8
Vitamin C mitigates flu pneumonia
A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice.
We examined the effects of vitamin C on pneumonia caused by the influenza virus, specifically the H1N1 strain, in mice under stress. The study found that when exposed to restraint stress, the mice experienced increased mortality and more severe pneumonia symptoms.
However, by giving them oral vitamin C at doses of 125 and 250 mg/kg, we observed a significant reduction in these severe outcomes. Vitamin C seemed to modulate the expression of certain genes related to the immune response, such as MAVS and IRF3, and increased the expression of NF-κB, which plays a key role in the body's antiviral defense.
Our research suggested that vitamin C's protective effects might stem from its ability to inhibit excess cortisol production in the adrenal gland, which is often elevated due to stress. By lowering cortisol levels, vitamin C may help reduce susceptibility to influenza infections, making it a potential ally during the flu season, especially for those experiencing stress.
Through these findings, we highlighted a new mechanism for how vitamin C can be beneficial during influenza infections, particularly for those who are feeling overwhelmed.
References
Abioye AI, Bromage S, Fawzi W. Effect of micronutrient supplements on influenza and other respiratory tract infections among adults: a systematic review and meta-analysis. BMJ Glob Health. 2021;6. 10.1136/bmjgh-2020-003176
Márquez-Domínguez L, Reyes-Leyva J, Herrera-Camacho I, Santos-López G, Scior T. Five Novel Non-Sialic Acid-Like Scaffolds Inhibit In Vitro H1N1 and H5N2 Neuraminidase Activity of Influenza a Virus. Molecules. 2020;25. 10.3390/molecules25184248
Kim H, Jang M, Kim Y, Choi J, Jeon J, et al. Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection. J Pharm Pharmacol. 2016;68:406. 10.1111/jphp.12529
Wang H, Xu R, Shi Y, Si L, Jiao P, et al. Design, synthesis and biological evaluation of novel L-ascorbic acid-conjugated pentacyclic triterpene derivatives as potential influenza virus entry inhibitors. Eur J Med Chem. 2016;110:376. 10.1016/j.ejmech.2016.01.005
Cai Y, Li YF, Tang LP, Tsoi B, Chen M, et al. A new mechanism of vitamin C effects on A/FM/1/47(H1N1) virus-induced pneumonia in restraint-stressed mice. Biomed Res Int. 2015;2015:675149. 10.1155/2015/675149