Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
USERS' SCORE
Excellent
Based on 13 Reviews
9.1
Supplement Facts
Serving Size: 1 Vegetable capsule
Amount Per Serving
%DV
Thiamin (vitamin B1) (as thiamin mononitrate)
100 mg
8,333%
Riboflavin (vitamin B2)
100 mg
7,692%
Niacin (vitamin B3) (as niacinamide)
100 mg
625%
Vitamin B6 (as pyridoxine HCl)
100 mg
5,882%
Folate
666 mcg DFE(400 mcg folic acid)
167%
Vitamin B12 (as cyanocobalamin)
100 mcg
4,167%
Biotin (as d-biotin)
100 mcg
333%
Pantothenic Acid (vitamin B5) (as d-calcium pantothenate)
100 mg
2,000%
Choline (as choline bitartrate)
20 mg
4%
Inositol
100 mg
**

Top Medical Research Studies

8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More

Most Useful Reviews

10
Highly recommended
340 people found this helpful
This fantastic product is recommended for those with anxiety or depression. I've been using it for about six years, having previously suffered from severe anxiety and panic attacks. After addressing deficiencies in vitamins D3 and B12, I was finally able to function. This is highly recommended for anyone experiencing anxiety or depression.
Read More
9
Effective for anxiety
19 people found this helpful
100% Effective! This is the first supplement I've tried that truly worked. My eye twitching, off-season stress, and internal anxiety have all improved. I'll be purchasing this regularly.
Read More
9
Supports anxiety relief
1 people found this helpful
B vitamins provide significant benefits to our nervous system, improving sleep and reducing anxiety. For best effects, I recommend taking them in combination with magnesium.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.3
  • All Researches
8
Niacin helps alleviate anxiety symptoms
We examined the impact of Niacin on anxiety and memory loss caused by aging in a rat study. Rats were grouped and treated with various doses of Niacin and D-galactose for 14 days, followed by behavioral tests to assess anxiety and memory.

Our results showed that Niacin significantly reduced anxiety-like symptoms and improved memory deficits. Additionally, it mitigated factors like oxidative stress and inflammation, enhancing brain health. Overall, Niacin's antioxidant and neuro-modulatory properties suggest it may be beneficial in addressing aging-related psychiatric issues.
Read More
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.
Read More
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
Read More
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.

Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
Read More
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 13 Reviews
9.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Highly recommended
340 people found this helpful
This fantastic product is recommended for those with anxiety or depression. I've been using it for about six years, having previously suffered from severe anxiety and panic attacks. After addressing deficiencies in vitamins D3 and B12, I was finally able to function. This is highly recommended for anyone experiencing anxiety or depression.
Read More
9
Effective for anxiety
19 people found this helpful
100% Effective! This is the first supplement I've tried that truly worked. My eye twitching, off-season stress, and internal anxiety have all improved. I'll be purchasing this regularly.
Read More
9
Supports anxiety relief
1 people found this helpful
B vitamins provide significant benefits to our nervous system, improving sleep and reducing anxiety. For best effects, I recommend taking them in combination with magnesium.
Read More
10
Anxiety reduction
I struggled with anxiety and insomnia due to thyroid issues. This B complex has been the best for calming my mind and alleviating my symptoms.
Read More
9
Peace of mind
I regularly purchase these for myself and family. One a day helps us manage nerves and anxiety effectively. Our peace of mind has significantly improved.
Read More

Frequently Asked Questions

7.5
Calmness restored
12 people found this helpful
Take it seriously while in uniform. Since I started taking vitamins, my anxiety and tension have significantly reduced. I feel very calm now.
9
Peace of mind
I regularly purchase these for myself and family. One a day helps us manage nerves and anxiety effectively. Our peace of mind has significantly improved.
9
Effective for anxiety
19 people found this helpful
100% Effective! This is the first supplement I've tried that truly worked. My eye twitching, off-season stress, and internal anxiety have all improved. I'll be purchasing this regularly.
9
Supports anxiety relief
1 people found this helpful
B vitamins provide significant benefits to our nervous system, improving sleep and reducing anxiety. For best effects, I recommend taking them in combination with magnesium.
10
Anxiety reduction
I struggled with anxiety and insomnia due to thyroid issues. This B complex has been the best for calming my mind and alleviating my symptoms.
6
Increased strength
2 people found this helpful
I’ve heard that B vitamins are not well absorbed when taken together, so I usually take them separately. However, with this product's high concentration, I feel that something beneficial is indeed happening. I seem to have more strength and less anxiety. I also take it with magnesium from the same brand.
7.5
Stress management
2 people found this helpful
Whenever I feel overwhelmed, I double my dose, and my anxiety and stress become much easier to manage.
7
Vitamin B may alleviate anxiety symptoms
We investigated how Vitamin B can affect anxiety and depression in a rat model facing chronic stress. Seventy-two rats were divided into three groups: a control group, a stressed group, and a stressed group receiving Vitamin B injections.

The study measured behavioral changes and key neurotransmitter levels. Results showed that Vitamin B helped restore neurotransmitter levels and improved the rats' behavior. This suggests that Vitamin B could potentially play a role in alleviating anxiety and depressive symptoms by supporting brain health.
7
Vitamin B aids anxiety recovery
We explored the effects of vitamin B supplementation on anxiety and cognitive function in male Swiss albino mice following traumatic brain injury (TBI). Our research found that vitamin B appears to improve neurological impairments, enhance memory, and reduce anxiety-like behaviors.

Additionally, we saw a reduction in oxidative stress markers, indicating better neuronal health. This suggests that vitamin B not only helps with anxiety but also plays a role in recovery from cognitive dysfunctions associated with TBI.
7
No significant anxiety improvement
We explored the effectiveness of vitamin B complex in treating anxiety among patients with Post-COVID-19 syndrome (PC19S) through the PreVitaCOV trial. This study involved 240 participants who were given either prednisolone, vitamin B1, B6, and B12, a combination of these treatments, or a placebo. While the trial showed high feasibility and safety, it ultimately did not demonstrate significant benefits in symptom change over placebo in anxiety or other evaluated symptoms.
We explored how vitamin B could help fight anxiety and depression linked to nicotine withdrawal in young male rats.

The study involved giving some rats nicotine before dividing them into different groups, where some were treated with vitamin B and others with bupropion—a common anxiety medication.

The results were promising, with vitamin B showing potential in reducing anxiety symptoms, comparable to bupropion. This opens the door for vitamin B as a possible new treatment option for various anxiety-related issues.

References

  1. Chen J, Liu J, Zhang P, Zhang S. [Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2025;56:206. doi:10.12182/20250160608
  2. Samad N, Hameed A, Manzoor N, Shoukat S, Irfan A, et al. Antioxidant and neuro-modulatory effects of niacin prevent D-galactose-induced behavioral deficits and memory impairment. Exp Gerontol. 2024;198:112624. doi:10.1016/j.exger.2024.112624
  3. Yadav P, Nasir F, Sivanandam TM. Neuroprotective effect of vitamin B supplementation on cognitive functions and neuronal morphology at different time intervals after traumatic brain injury in male Swiss albino mice. Neurochem Int. 2024;180:105869. doi:10.1016/j.neuint.2024.105869
  4. Tengelmann C, Joos S, Kaußner Y, Malzahn U, Lunden L, et al. Feasibility, safety and effectiveness of prednisolone and vitamin B1, B6, and B12 in patients with post-COVID-19-syndrome (PreVitaCOV) - protocol of a randomised, double-blind, placebo-controlled multicentre trial in primary care (phase IIIb). BMC Infect Dis. 2024;24:56. doi:10.1186/s12879-023-08925-2
  5. Pahlavani H, Masoudi M, Khoshroo N, Kakhki S, Mahdi Rezavanimehr M, et al. Vitamin B reversed anxiety and depression induced by adolescent nicotine withdrawal through alteration the inflammatory, oxidative and serotoninergic profiles in male rats. Biochem Pharmacol. 2023;217:115832. doi:10.1016/j.bcp.2023.115832
  6. Kakhki S, Goodarzi M, Abbaszade-Cheragheali A, Rajabi M, Masoumipour AH, et al. Folic acid supplementation improved cognitive deficits associated with lithium administration during pregnancy in rat offspring. Int J Dev Neurosci. 2023;83:615. doi:10.1002/jdn.10289
  7. Shemirani F, Titcomb TJ, Saxby SM, Eyck PT, Rubenstein LM, et al. Association of serum homocysteine, folate, and vitamin B and mood following the Swank and Wahls elimination dietary interventions in relapsing-remitting multiple sclerosis: Secondary analysis of the WAVES trial. Mult Scler Relat Disord. 2023;75:104743. doi:10.1016/j.msard.2023.104743
image