Overview
![Solgar Solgar B-Complex "100"](https://m.media-amazon.com/images/I/41OvoQlDt2L._SL500_.jpg "Solgar Solgar B-Complex "100"")
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.7
USERS' SCORE
Good
Based on 7 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetable capsule
Amount Per Serving
%DV
Thiamin (vitamin B1) (as thiamin mononitrate)
100 mg
8,333%
Riboflavin (vitamin B2)
100 mg
7,692%
Niacin (vitamin B3) (as niacinamide)
100 mg
625%
Vitamin B6 (as pyridoxine HCl)
100 mg
5,882%
Folate
666 mcg DFE(400 mcg folic acid)
167%
Vitamin B12 (as cyanocobalamin)
100 mcg
4,167%
Biotin (as d-biotin)
100 mcg
333%
Pantothenic Acid (vitamin B5) (as d-calcium pantothenate)
100 mg
2,000%
Choline (as choline bitartrate)
20 mg
4%
Inositol
100 mg
**
Top Medical Research Studies
9
In our review and meta-analysis, we sought to understand how Vitamin B2 supplementation influences migraines. By examining nine studies with over 670 participants, we found that taking 400 mg of Vitamin B2 daily for three months significantly reduced the frequency, duration, and pain intensity of migraine attacks.
Our analysis revealed that Vitamin B2 wasn't just a minor help; it truly made a difference in managing migraine symptoms. This suggests a potential alternative to traditional pharmaceuticals, offering hope for migraine sufferers looking for effective prevention options.
Our analysis revealed that Vitamin B2 wasn't just a minor help; it truly made a difference in managing migraine symptoms. This suggests a potential alternative to traditional pharmaceuticals, offering hope for migraine sufferers looking for effective prevention options.
Read More
9
We conducted a retrospective observational study involving 42 children and adolescents, aged six to 18, to assess the effectiveness of riboflavin in managing migraines.
Participants saw significant improvements, with fewer headache days per month and reduced headache intensity and duration after starting riboflavin.
Additionally, we found a decrease in reliance on acute medications and missed school days related to migraines, suggesting riboflavin is a safe and beneficial option for young migraine sufferers.
Participants saw significant improvements, with fewer headache days per month and reduced headache intensity and duration after starting riboflavin.
Additionally, we found a decrease in reliance on acute medications and missed school days related to migraines, suggesting riboflavin is a safe and beneficial option for young migraine sufferers.
Read More
8
We analyzed the role of vitamin B2, or riboflavin, in preventing migraines for adults. Our findings indicate that riboflavin is recommended for migraine prevention, though pediatric use lacks evidence.
While the adverse events associated with riboflavin are minimal, we noted that other nutraceuticals show varying levels of support for migraine treatment. Most notably, magnesium is also recommended for prevention and treatment, while coenzyme Q10 has limited evidence.
However, we observed that some supplements, like feverfew, require caution due to safety uncertainties. Overall, riboflavin stands out as a viable option for adults seeking relief from migraines.
While the adverse events associated with riboflavin are minimal, we noted that other nutraceuticals show varying levels of support for migraine treatment. Most notably, magnesium is also recommended for prevention and treatment, while coenzyme Q10 has limited evidence.
However, we observed that some supplements, like feverfew, require caution due to safety uncertainties. Overall, riboflavin stands out as a viable option for adults seeking relief from migraines.
Read More
Most Useful Reviews
9
Migraine reduction
18 people found this helpful
Trims migraine attacks. This has been my salvation! As a doctor, I initially doubted that migraine is a metabolic disease. However, the effect was significant: my episodes reduced significantly. When I tried to stop taking this complex, the migraines returned. With this supplement, I use only 1 pack of triptans monthly, compared to 6-7 packs without it.
Read More
10
Migraine elimination success
5 people found this helpful
Solgar B-Complex 100 is essential for me. I have taken it since 2005 and believe it eliminated my migraines that I suffered from since puberty! After about six months, they disappeared. I also use it for stress, mood swings, and energy. Whenever I have projects at home, I ensure to take my B-complex to energise me!
Read More
7.5
Fewer migraines
2 people found this helpful
I began daily use of this product based on a recommendation for menopausal women's health. I was pleasantly surprised, as it significantly improved my memory and concentration. To my delight, it also lessened my migraines, especially when paired with magnesium from the same company, reducing both frequency and intensity.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.7
- All Researches
9
In our review and meta-analysis, we sought to understand how Vitamin B2 supplementation influences migraines. By examining nine studies with over 670 participants, we found that taking 400 mg of Vitamin B2 daily for three months significantly reduced the frequency, duration, and pain intensity of migraine attacks.
Our analysis revealed that Vitamin B2 wasn't just a minor help; it truly made a difference in managing migraine symptoms. This suggests a potential alternative to traditional pharmaceuticals, offering hope for migraine sufferers looking for effective prevention options.
Our analysis revealed that Vitamin B2 wasn't just a minor help; it truly made a difference in managing migraine symptoms. This suggests a potential alternative to traditional pharmaceuticals, offering hope for migraine sufferers looking for effective prevention options.
Read More
9
We conducted a retrospective observational study involving 42 children and adolescents, aged six to 18, to assess the effectiveness of riboflavin in managing migraines.
Participants saw significant improvements, with fewer headache days per month and reduced headache intensity and duration after starting riboflavin.
Additionally, we found a decrease in reliance on acute medications and missed school days related to migraines, suggesting riboflavin is a safe and beneficial option for young migraine sufferers.
Participants saw significant improvements, with fewer headache days per month and reduced headache intensity and duration after starting riboflavin.
Additionally, we found a decrease in reliance on acute medications and missed school days related to migraines, suggesting riboflavin is a safe and beneficial option for young migraine sufferers.
Read More
8
We analyzed the role of vitamin B2, or riboflavin, in preventing migraines for adults. Our findings indicate that riboflavin is recommended for migraine prevention, though pediatric use lacks evidence.
While the adverse events associated with riboflavin are minimal, we noted that other nutraceuticals show varying levels of support for migraine treatment. Most notably, magnesium is also recommended for prevention and treatment, while coenzyme Q10 has limited evidence.
However, we observed that some supplements, like feverfew, require caution due to safety uncertainties. Overall, riboflavin stands out as a viable option for adults seeking relief from migraines.
While the adverse events associated with riboflavin are minimal, we noted that other nutraceuticals show varying levels of support for migraine treatment. Most notably, magnesium is also recommended for prevention and treatment, while coenzyme Q10 has limited evidence.
However, we observed that some supplements, like feverfew, require caution due to safety uncertainties. Overall, riboflavin stands out as a viable option for adults seeking relief from migraines.
Read More
8
Vitamin B12 and magnesium effective
We set out to investigate whether combining vitamin B12, magnesium, and high-intensity interval training (HIIT) could help reduce migraine symptoms. In a randomized, placebo-controlled trial with 60 participants, we split them into four groups to assess various interventions over two months. Our findings showed that the combination of B12, magnesium, and regular exercise had significant benefits in reducing migraine pain and inflammation. This suggests that a synergistic approach could effectively improve migraine management.
Read More
8
We examined the potential benefits of vitamin B6, folate, and B12 for treating migraines, particularly migraine with aura (MA). Our systematic literature search gathered 12 studies, revealing that while these vitamins didn't significantly help with acute migraines, B6 showed promise when used preventively alongside folate and B12 in adults with MA. However, folate alone didn’t perform better than a placebo. Unfortunately, data on migraine without aura (MO) in both adults and children were limited, emphasizing the need for more rigorous studies.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Migraine reduction
18 people found this helpful
Trims migraine attacks. This has been my salvation! As a doctor, I initially doubted that migraine is a metabolic disease. However, the effect was significant: my episodes reduced significantly. When I tried to stop taking this complex, the migraines returned. With this supplement, I use only 1 pack of triptans monthly, compared to 6-7 packs without it.
Read More
10
Migraine elimination success
5 people found this helpful
Solgar B-Complex 100 is essential for me. I have taken it since 2005 and believe it eliminated my migraines that I suffered from since puberty! After about six months, they disappeared. I also use it for stress, mood swings, and energy. Whenever I have projects at home, I ensure to take my B-complex to energise me!
Read More
7.5
Fewer migraines
2 people found this helpful
I began daily use of this product based on a recommendation for menopausal women's health. I was pleasantly surprised, as it significantly improved my memory and concentration. To my delight, it also lessened my migraines, especially when paired with magnesium from the same company, reducing both frequency and intensity.
Read More
9
Disappearing migraines
1 people found this helpful
A great product with excellent composition. After taking it for two months, I noticed my migraines vanished, my skin became more elastic, and I felt more energetic. I happily recommend it to friends.
Read More
0
Hepatic migraines
1 people found this helpful
I find this supplement difficult to digest. It gives me hepatic migraines, which I suspect may be due to an ingredient or dosage. While I'm usually confident in Solgar's quality, I'm disappointed this time.
Read More
Frequently Asked Questions
9
Disappearing migraines
1 people found this helpful
A great product with excellent composition. After taking it for two months, I noticed my migraines vanished, my skin became more elastic, and I felt more energetic. I happily recommend it to friends.
7.5
Migraine symptoms reduced
I'm 39 and took this complex for two months. I stopped suffering from meteosensitivity and migraine attacks that preceded my menstruation. After a month off, symptoms returned, so I ordered a larger package to see how it helps.
7.5
Fewer migraines
2 people found this helpful
I began daily use of this product based on a recommendation for menopausal women's health. I was pleasantly surprised, as it significantly improved my memory and concentration. To my delight, it also lessened my migraines, especially when paired with magnesium from the same company, reducing both frequency and intensity.
9
Migraine reduction
18 people found this helpful
Trims migraine attacks. This has been my salvation! As a doctor, I initially doubted that migraine is a metabolic disease. However, the effect was significant: my episodes reduced significantly. When I tried to stop taking this complex, the migraines returned. With this supplement, I use only 1 pack of triptans monthly, compared to 6-7 packs without it.
9
No more migraines
This set is perfect for me. After suffering from migraines and sensitivity to weather changes, I found that after the course, both my migraines and lethargy disappeared. I've experienced better energy levels and improved sleep.
0
Hepatic migraines
1 people found this helpful
I find this supplement difficult to digest. It gives me hepatic migraines, which I suspect may be due to an ingredient or dosage. While I'm usually confident in Solgar's quality, I'm disappointed this time.
References
- Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
- Li H, Krall JR, Frankenfeld C, Slavin M. Nutritional intake of riboflavin (vitamin B2) and migraine: a cross-sectional analysis of the National Health and Nutrition Examination Survey (NHANES) 2001-2004. Nutr Neurosci. 2023;26:1068. doi:10.1080/1028415X.2022.2126760
- Li D, Guo Y, Xia M, Zhang J, Zang W. Dietary intake of thiamine and riboflavin in relation to severe headache or migraine: A cross-sectional survey. Headache. 2022;62:1133. doi:10.1111/head.14384
- Liu H, Wang L, Chen C, Dong Z, Yu S. Association between Dietary Niacin Intake and Migraine among American Adults: National Health and Nutrition Examination Survey. Nutrients. 2022;14. doi:10.3390/nu14153052
- Matin H, Taghian F, Chitsaz A. Artificial intelligence analysis to explore synchronize exercise, cobalamin, and magnesium as new actors to therapeutic of migraine symptoms: a randomized, placebo-controlled trial. Neurol Sci. 2022;43:4413. doi:10.1007/s10072-021-05843-6
- Chen YS, Lee HF, Tsai CH, Hsu YY, Fang CJ, et al. Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis. Nutr Neurosci. 2022;25:1801. doi:10.1080/1028415X.2021.1904542
- Das R, Qubty W. Retrospective Observational Study on Riboflavin Prophylaxis in Child and Adolescent Migraine. Pediatr Neurol. 2021;114:5. doi:10.1016/j.pediatrneurol.2020.09.009
- Yamanaka G, Suzuki S, Takeshita M, Go S, Morishita N, et al. Effectiveness of low-dose riboflavin as a prophylactic agent in pediatric migraine. Brain Dev. 2020;42:523. doi:10.1016/j.braindev.2020.04.002
- Liampas IN, Siokas V, Aloizou AM, Tsouris Z, Dastamani M, et al. Pyridoxine, folate and cobalamin for migraine: A systematic review. Acta Neurol Scand. 2020;142:108. doi:10.1111/ane.13251
- Togha M, Razeghi Jahromi S, Ghorbani Z, Martami F, Seifishahpar M. Serum Vitamin B12 and Methylmalonic Acid Status in Migraineurs: A Case-Control Study. Headache. 2019;59:1492. doi:10.1111/head.13618
- Askari G, Nasiri M, Mozaffari-Khosravi H, Rezaie M, Bagheri-Bidakhavidi M, et al. The effects of folic acid and pyridoxine supplementation on characteristics of migraine attacks in migraine patients with aura: A double-blind, randomized placebo-controlled, clinical trial. Nutrition. 2017;38:74. doi:10.1016/j.nut.2017.01.007
- Thompson DF, Saluja HS. Prophylaxis of migraine headaches with riboflavin: A systematic review. J Clin Pharm Ther. 2017;42:394. doi:10.1111/jcpt.12548
- Prakash S, Kumar Singh A, Rathore C. Chronic Migraine Responding to Intravenous Thiamine: A Report of Two Cases. Headache. 2016;56:1204. doi:10.1111/head.12838
- Namazi N, Heshmati J, Tarighat-Esfanjani A. Supplementation with Riboflavin (Vitamin B2) for Migraine Prophylaxis in Adults and Children: A Review. Int J Vitam Nutr Res. 2015;85:79. doi:10.1024/0300-9831/a000225
- Gaul C, Diener HC, Danesch U. Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial. J Headache Pain. 2015;16:516. doi:10.1186/s10194-015-0516-6
