We observed two adolescents struggling with severe sleep-wake schedule disorders respond positively to high doses of vitamin B12, specifically methylcobalamin. The 15-year-old girl with delayed sleep phase syndrome and the 17-year-old boy with hypernychthemeral syndrome showed immediate improvements after receiving 3,000 micrograms per day.
Notably, there was no evidence of vitamin B12 deficiency in either case, as their levels remained in the normal range. The girl's sleep duration reduced from 10 hours to 7 hours, while the onset of her sleep moved from 2 a.m. to midnight. The boy's sleep-wake cycle also adjusted slightly, indicating potential benefits of methylcobalamin for these disorders.
Read More
9
Thiamine deficiency affects mental health
What can cause cancer patients to attempt suicide? Thiamine deficiency mimicking the symptoms of major depressive disorder.
We examined a unique case of a 58-year-old woman with recurrent endometrial cancer who showed signs of severe depression and attempted suicide. Initially, her symptoms were believed to be linked to major depressive disorder.
However, after administering intravenous thiamine due to her dietary deficiencies, we noticed remarkable changes. Her insomnia, palpitations, and other concerning symptoms improved dramatically within just an hour, and her suicidal thoughts completely vanished.
This case underlines the importance of recognizing thiamine deficiency as a potential reversible cause of psychiatric symptoms, rather than simply attributing them to depression alone.
Read More
8
Vitamin B12 aids specific sleep disorders
Vitamin B12 treatment for sleep-wake rhythm disorders.
We looked into the effects of Vitamin B12 on two patients with long-standing sleep-wake rhythm disorders.
The first patient, a 15-year-old blind girl with a free-running sleep-wake cycle, saw her rhythm align with the environmental 24-hour cycle shortly after starting a daily dose of 1.5 mg of B12. Unfortunately, her sleep issues returned after stopping the B12 treatment.
The second patient, a 55-year-old man with delayed sleep phase syndrome, experienced improvement for over six months while on the same dosage.
While results were promising for these individuals, further research is necessary to better understand the broader effectiveness of Vitamin B12 for insomnia.
Read More
Most Useful Reviews
9
Improved sleep quality
203 people found this helpful
Capsules are of a manageable size for me, taken with breakfast. I noticed my insomnia has vanished, and I've felt a desire for more sleep, which is beneficial as I struggled with sleep for months. I've also become less irritable, much to my family's delight.
Read More
9
Insomnia relief
7 people found this helpful
I decided to try this vitamin complex to combat insomnia and irritability. After starting, I found I slept better and craved even more sleep. My irritability decreased significantly, and I even had more energy for household tasks. My hair and skin improved as well. Highly recommended!
Read More
9
Reduced fatigue
4 people found this helpful
A year ago, I began taking B vitamins after struggling with fatigue and insomnia. They have boosted my energy, calmed my irritability, and improved my sleep quality. I now wake up feeling more alert and refreshed. I recommend them for anyone facing similar issues after consulting a doctor.
We examined a unique case of a 58-year-old woman with recurrent endometrial cancer who showed signs of severe depression and attempted suicide. Initially, her symptoms were believed to be linked to major depressive disorder.
However, after administering intravenous thiamine due to her dietary deficiencies, we noticed remarkable changes. Her insomnia, palpitations, and other concerning symptoms improved dramatically within just an hour, and her suicidal thoughts completely vanished.
This case underlines the importance of recognizing thiamine deficiency as a potential reversible cause of psychiatric symptoms, rather than simply attributing them to depression alone.
Read More
8
Vitamin B6 combined with melatonin beneficial
A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study.
In a 4-week open-label study involving 40 individuals with mild-to-moderate insomnia, we explored the effects of a combination formula containing melatonin and vitamin B6.
Participants reported significant improvements in sleep quality, with average scores rising from 5.4 to 7.3 after two weeks.
Our findings also indicated enhancements in sleep onset latency and total sleep duration, all without serious side effects.
Overall, this combination treatment shows promise for those struggling with insomnia.
Read More
8
Vitamin B12 aids specific sleep disorders
Vitamin B12 treatment for sleep-wake rhythm disorders.
We looked into the effects of Vitamin B12 on two patients with long-standing sleep-wake rhythm disorders.
The first patient, a 15-year-old blind girl with a free-running sleep-wake cycle, saw her rhythm align with the environmental 24-hour cycle shortly after starting a daily dose of 1.5 mg of B12. Unfortunately, her sleep issues returned after stopping the B12 treatment.
The second patient, a 55-year-old man with delayed sleep phase syndrome, experienced improvement for over six months while on the same dosage.
While results were promising for these individuals, further research is necessary to better understand the broader effectiveness of Vitamin B12 for insomnia.
Read More
7
Vitamin B Complex shows promise
Enhancing Sleep Quality: Assessing the Efficacy of a Fixed Combination of Linden, Hawthorn, Vitamin B1, and Melatonin.
We evaluated the effectiveness of a nutritional supplement, SPINOFF, on sleep quality and mental health in a pilot study involving 41 participants. Initially, participants reported significant sleep issues and psychological distress.
After a 30-day treatment period, we observed significant reductions in both insomnia symptoms and sleep disturbances, with improved scores indicating better sleep quality and reduced psychological distress. For those who continued treatment, enhancements were even more pronounced.
Overall, our findings suggest that the SPINOFF supplement could be beneficial in tackling sleep difficulties and mental wellness.
Read More
7
Vitamin B12 aids sleep disorders
Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12).
We observed two adolescents struggling with severe sleep-wake schedule disorders respond positively to high doses of vitamin B12, specifically methylcobalamin. The 15-year-old girl with delayed sleep phase syndrome and the 17-year-old boy with hypernychthemeral syndrome showed immediate improvements after receiving 3,000 micrograms per day.
Notably, there was no evidence of vitamin B12 deficiency in either case, as their levels remained in the normal range. The girl's sleep duration reduced from 10 hours to 7 hours, while the onset of her sleep moved from 2 a.m. to midnight. The boy's sleep-wake cycle also adjusted slightly, indicating potential benefits of methylcobalamin for these disorders.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.6
All Reviews
Positive Reviews
Negative Reviews
9
Improved sleep quality
203 people found this helpful
Capsules are of a manageable size for me, taken with breakfast. I noticed my insomnia has vanished, and I've felt a desire for more sleep, which is beneficial as I struggled with sleep for months. I've also become less irritable, much to my family's delight.
Read More
9
Insomnia relief
7 people found this helpful
I decided to try this vitamin complex to combat insomnia and irritability. After starting, I found I slept better and craved even more sleep. My irritability decreased significantly, and I even had more energy for household tasks. My hair and skin improved as well. Highly recommended!
Read More
9
Reduced fatigue
4 people found this helpful
A year ago, I began taking B vitamins after struggling with fatigue and insomnia. They have boosted my energy, calmed my irritability, and improved my sleep quality. I now wake up feeling more alert and refreshed. I recommend them for anyone facing similar issues after consulting a doctor.
Read More
9
Better sleep
1 people found this helpful
The capsules are of an adequate size and don't present issues while taking. I use them during breakfast, which has resulted in my insomnia disappearing, and I've started wanting more sleep—a significant improvement for me as I had struggled for months.
Read More
0
Insomnia side effect
I found the quality of B vitamins nice, but unfortunately, they have caused me insomnia.
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Vitamin B Complex refers to a group of water-soluble vitamins that play important roles in cell metabolism and overall health. This group typically includes eight essential vitamins: B1 (thiamine), B2 (riboflavin), B3 (niacin), B5 (pantothenic acid), B6 (pyridoxine), B7 (biotin), B9 (folate), and B12 (cobalamin). Each of these vitamins contributes uniquely to various bodily functions, such as energy production, red blood cell formation, and nervous system function. For instance, B12 and folate are crucial in preventing anemia, while B6 is vital for brain development and function.
Many people can obtain their daily requirements of B vitamins through a balanced diet that includes whole grains, meats, eggs, nuts, leafy greens, and dairy products. However, certain groups—like vegetarians, pregnant women, and older adults—may benefit from supplementation to meet their nutritional needs. It's important to consult with a healthcare professional before starting any supplement regimen, as excessive intake of certain B vitamins can lead to adverse effects. Overall, ensuring adequate intake of Vitamin B Complex is vital for maintaining energy levels and supporting overall health.
While Vitamin B Complex is essential for overall health and wellbeing, its specific role in alleviating insomnia is somewhat complex. B vitamins, including B6, B9 (folate), and B12, are involved in the synthesis of neurotransmitters that regulate mood and sleep cycles, such as serotonin and melatonin. Some studies suggest that deficiencies in these vitamins can lead to sleep disruptions, which means adequate levels could potentially support better sleep quality. However, the evidence directly linking Vitamin B Complex supplementation to improved insomnia is still limited and more research is needed.
If you are considering using Vitamin B Complex to help with insomnia, it's important to consult a healthcare professional first. They can guide you in determining if a deficiency may be contributing to your sleep issues and recommend appropriate dosages or alternatives. Additionally, focusing on a balanced diet rich in these vitamins, rather than relying solely on supplements, can help support your overall sleep health.
Based on user reviews, many individuals began to notice improvements relating to insomnia after starting the supplement within a short period. For instance, one reviewer indicated that their insomnia vanished shortly after they began taking the capsules, allowing them to feel a desire for more sleep, which they had struggled to achieve for months Read Review. Similarly, another user mentioned that they experienced better sleep and decreased irritability soon after incorporating the vitamin complex into their routine Read Review.
However, results can vary, as some users have reported inconsistent effects. While one person found their insomnia lessened significantly, attributing part of their improvement to the B vitamins, they still experienced occasional trouble sleeping Read Review. Another reviewer mentioned that while the supplement didn’t completely solve their insomnia, it did help improve their overall sleep quality when taken at night Read Review. Overall, while many users report positive changes relatively quickly, the time frame can depend on individual health circumstances and habits.
The use of nutritional supplements for insomnia has garnered attention in recent research, with varying degrees of success reported across different ingredients. For instance, a pilot study involving the supplement SPINOFF indicated that it led to significant reductions in insomnia symptoms and sleep disturbances among participants after a 30-day treatment period, coupled with improved overall sleep quality and mental health metrics [1]. This suggests that SPINOFF could be a viable option for individuals struggling with sleep difficulties.
Additionally, other ingredients like melatonin and vitamin B6 have also shown promise. In a study involving these compounds, participants experienced notable improvements in sleep quality and duration without major side effects, highlighting their potential effectiveness for those dealing with mild to moderate insomnia [3]. Meanwhile, vitamin B12 has also been indicated to potentially benefit specific sleep-wake disorders, although results varied and indicated a need for further exploration [4][5]. Overall, the scientific research supports the potential of specific supplements in alleviating insomnia symptoms, although more extensive studies are warranted to comprehensively understand their efficacy.
Based on user reviews, many individuals have reported noticeable improvements in their symptoms after incorporating the supplement into their daily routine. For example, one user observed that their insomnia vanished shortly after starting the capsules, leading to an increased desire for sleep that they hadn't experienced for months Read Review. Another reviewer echoed similar sentiments, stating that their sleep quality improved significantly, coupled with a marked decrease in irritability and an overall boost in energy Read Review.
However, it's important to note that individual results can vary. While many users report positive changes, such as feeling less fatigued and waking up more refreshed, some have experienced inconsistent effects. For instance, one reviewer indicated that, although their insomnia lessened, they still occasionally faced sleep disturbances Read Review. Additionally, another user shared that while the supplement didn't fully resolve their insomnia, it did contribute to better sleep quality when taken as directed Read Review. Overall, while many users have enjoyed significant benefits, the time frame and degree of effectiveness can depend on individual health conditions and habits.
Based on user reviews, combining this supplement with other aids for insomnia may yield mixed results. Some users reported that taking B vitamins along with other supplements improved their sleep quality and reduced fatigue. For instance, one reviewer noted a decrease in insomnia when they began taking B vitamins alongside others, indicating they felt less tired and more confident about sleeping Read Review. However, there were also conflicting experiences; one individual reported that taking the vitamins caused them insomnia, suggesting that their specific combination may not have been suitable for everyone Read Review.
Moreover, some users emphasized the importance of timing, with one stating that taking B vitamins in the morning helped prevent insomnia at night, thus indicating that the effectiveness may also depend on when they are consumed in relation to other sleep aids Read Review. Overall, while some users found successful combinations, the outcomes may vary significantly based on individual health circumstances and the specific supplements used.
Based on user reviews, many individuals report positive experiences with taking Vitamin B Complex for insomnia, suggesting that the right dose can significantly improve sleep quality. Several users mentioned that taking the capsules in the morning has been effective for them, as one reviewer noted a complete disappearance of their insomnia when taken at breakfast (Read Review). Others echoed this sentiment, claiming that they not only experienced better sleep but also increased energy levels throughout the day (Read Review).
However, it is important to note that not all experiences were positive. One user indicated that the vitamins caused them insomnia instead of alleviating it, which highlights the need for individuals to monitor their own reactions and possibly adjust the timing and dosage of their intake (Read Review). The feedback suggests that a morning regimen may be beneficial for most, but tailoring the dose and timing could be necessary for those who find themselves experiencing insomnia after taking the supplements.
9
Improved sleep quality
203 people found this helpful
Capsules are of a manageable size for me, taken with breakfast. I noticed my insomnia has vanished, and I've felt a desire for more sleep, which is beneficial as I struggled with sleep for months. I've also become less irritable, much to my family's delight.
9
Insomnia relief
7 people found this helpful
I decided to try this vitamin complex to combat insomnia and irritability. After starting, I found I slept better and craved even more sleep. My irritability decreased significantly, and I even had more energy for household tasks. My hair and skin improved as well. Highly recommended!
7.5
Less tired
2 people found this helpful
I’ve been fatigued for years and started taking B vitamins alongside others for better sleep. I do find I feel less tired now, and my insomnia has lessened. While I still occasionally have trouble sleeping, I feel more confident about my chances of rest.
7.5
Energetic mornings
2 people found this helpful
After years of dealing with insomnia, I have tried many products. Although Solar B-Complex doesn't solve my insomnia, it helps me sleep better when taken before bed, leading to more energetic mornings. I highly recommend it for anyone who faces similar challenges.
0
Insomnia side effect
I found the quality of B vitamins nice, but unfortunately, they have caused me insomnia.
7.5
Nervous system improvement
4 people found this helpful
This is my third order of these B vitamins, and I find them incredibly effective. I noticed improvements in my insomnia and overall nervous system shortly after I began taking them. It's essential to take them in the morning to avoid insomnia at night.
7
Vitamin B Complex shows promise
Enhancing Sleep Quality: Assessing the Efficacy of a Fixed Combination of Linden, Hawthorn, Vitamin B1, and Melatonin.
We evaluated the effectiveness of a nutritional supplement, SPINOFF, on sleep quality and mental health in a pilot study involving 41 participants. Initially, participants reported significant sleep issues and psychological distress.
After a 30-day treatment period, we observed significant reductions in both insomnia symptoms and sleep disturbances, with improved scores indicating better sleep quality and reduced psychological distress. For those who continued treatment, enhancements were even more pronounced.
Overall, our findings suggest that the SPINOFF supplement could be beneficial in tackling sleep difficulties and mental wellness.
8
Vitamin B6 combined with melatonin beneficial
A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study.
In a 4-week open-label study involving 40 individuals with mild-to-moderate insomnia, we explored the effects of a combination formula containing melatonin and vitamin B6.
Participants reported significant improvements in sleep quality, with average scores rising from 5.4 to 7.3 after two weeks.
Our findings also indicated enhancements in sleep onset latency and total sleep duration, all without serious side effects.
Overall, this combination treatment shows promise for those struggling with insomnia.
7
Vitamin B12 aids sleep disorders
Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12).
We observed two adolescents struggling with severe sleep-wake schedule disorders respond positively to high doses of vitamin B12, specifically methylcobalamin. The 15-year-old girl with delayed sleep phase syndrome and the 17-year-old boy with hypernychthemeral syndrome showed immediate improvements after receiving 3,000 micrograms per day.
Notably, there was no evidence of vitamin B12 deficiency in either case, as their levels remained in the normal range. The girl's sleep duration reduced from 10 hours to 7 hours, while the onset of her sleep moved from 2 a.m. to midnight. The boy's sleep-wake cycle also adjusted slightly, indicating potential benefits of methylcobalamin for these disorders.
8
Vitamin B12 aids specific sleep disorders
Vitamin B12 treatment for sleep-wake rhythm disorders.
We looked into the effects of Vitamin B12 on two patients with long-standing sleep-wake rhythm disorders.
The first patient, a 15-year-old blind girl with a free-running sleep-wake cycle, saw her rhythm align with the environmental 24-hour cycle shortly after starting a daily dose of 1.5 mg of B12. Unfortunately, her sleep issues returned after stopping the B12 treatment.
The second patient, a 55-year-old man with delayed sleep phase syndrome, experienced improvement for over six months while on the same dosage.
While results were promising for these individuals, further research is necessary to better understand the broader effectiveness of Vitamin B12 for insomnia.
References
De Simone M, De Feo R, Choucha A, Ciaglia E, Fezeu F. Enhancing Sleep Quality: Assessing the Efficacy of a Fixed Combination of Linden, Hawthorn, Vitamin B1, and Melatonin. Med Sci (Basel). 2023;12. doi:10.3390/medsci12010002
Ishida M, Sato S, Sato I, Yoshioka A, Uchida N, et al. What can cause cancer patients to attempt suicide? Thiamine deficiency mimicking the symptoms of major depressive disorder. Palliat Support Care. 2024;22:205. doi:10.1017/S1478951523001128
Lemoine P, Bablon JC, Da Silva C. A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study. Complement Ther Med. 2019;45:104. doi:10.1016/j.ctim.2019.05.024
Ohta T, Ando K, Iwata T, Ozaki N, Kayukawa Y, et al. Treatment of persistent sleep-wake schedule disorders in adolescents with methylcobalamin (vitamin B12). Sleep. 1991;14:414.
Okawa M, Mishima K, Nanami T, Shimizu T, Iijima S, et al. Vitamin B12 treatment for sleep-wake rhythm disorders. Sleep. 1990;13:15.