Solgar Solgar Biotin

We explored the effects of biotin treatment on hair loss through a case study of a girl diagnosed with biotinidase deficiency. Despite having no notable family history of the condition, her symptoms included problematic dermatitis, yellow hair, and alopecia.

After identifying low levels of biotinase and significant metabolic increases, the girl was found to have two specific mutations in her BTD gene linked to this deficiency. Following the diagnosis, we observed a clear response to biotin supplementation, with an initial dosage of 20 mg per day.

Remarkably, her dermatitis improved within a month, and her hair color returned to normal after three months of treatment. These findings suggest that biotin replacement therapy can have significant positive outcomes in cases related to biotinidase deficiency, connecting biotin to effective hair restoration.

9.5

Effective against hair loss

Most Useful Review

The best recommendation if you’re dealing with serious hair loss issues. The dosage beautifully supports nail health, while my skin feels silky and supple. I witnessed marked improvements by the second month, and I continued for the third to solidify these health benefits. These vitamins are considered the best globally, promising a 100% result. Investing in them is worthwhile, and I advise against experimenting with cheaper alternatives. Was it helpful? Definitely!

Regulation of immunological and inflammatory functions by biotin.

Most Relevant Research

We investigated the effects of biotin on immune responses and inflammatory conditions. Biotin, a necessary vitamin, plays a role in various metabolic pathways related to inflammation. While previous studies have suggested that biotin deficiency can lead to skin inflammation and immune issues, our findings highlight the potential of biotin supplementation in addressing metal allergies in animal models. However, significant improvements in allergy symptoms were not conclusively shown. Thus, while biotin may be beneficial, more research is needed to fully understand its impact on allergies.

9.5

Better allergy response

Most Useful Review

とても素晴らしい！ I've just started this product and my skin is in great shape. Previous biotin supplements caused reactions due to my allergy-prone constitution, but this one seems to work better. I plan to continue using it as I expect benefits for my skin, hair, and nails. The product size is easier to consume than expected.

Cold Sores details

Significant improvement

Most Useful Review

He is someone who suffers from cold sores. I watched a YouTuber living in Japan who also has them and is being treated with biotin by a dermatologist. I have noticed significant improvement while taking biotin, as it soothes the itching associated with cold sores.

Rash details

SCIENTIFIC SCORE

Moderately Effective

Based on 16 Researches

Biotin effectively improves rash symptoms

Dramatic Clinical Improvement With Biotin Mega-Dose Therapy in a Neonate With Holocarboxylase Synthetase Deficiency.

Most Relevant Research

We explored the effects of biotin therapy on a neonate suffering from a rare metabolic disorder known as holocarboxylase synthetase deficiency. After initiating a biotin mega-dose regimen, we observed impressive results, with the baby showing notable clinical improvement just one day later.

Within six days, mechanical ventilation was no longer necessary, and the child maintained stable health through follow-ups. This case underscores the importance of early genetic testing and how effective biotin can be in treating specific metabolic issues.

9.5

Cleared rashes

Most Useful Review

These vitamins are my favourite. After childbirth, my hair began to fall out, but upon starting these vitamins, everything appeared to restore itself; my skin is clearer, and the rashes have vanished. I cannot comment on nail growth, as I’ve had no issues in that area.

Ulcer details

Good. It appears to have a moderate effect on hair growth. However, small ulcers develop on the scalp, which vanish once I stop using it.

Depression details

Hair and nails improved

Most Useful Review

My hair, nails, and skin are currently flawless. After suffering from hair loss and brittle nails due to depression, I have been taking these tablets for three months. Now, my hair doesn’t fall out, even when brushing, and my nails are much stronger. Have patience, as it takes time for the body to respond, but it’s worth it.

Headache details

The capsules are large, and while the dose works, it seems excessively high. Each time I took them, I suffered from a headache, although my nails improved. Unfortunately, I also developed subcutaneous pimples. I completed the course but will opt for much lower dosages in future.

Autoimmune Disorder details

SCIENTIFIC SCORE

Possibly Effective

Based on 8 Researches

Moderate benefits, high testing interference

High-dose biotin for multiple sclerosis: A systematic review and meta-analyses of randomized controlled trials.

Most Relevant Research

We evaluated the effectiveness of high-dose biotin in treating multiple sclerosis through a systematic review of randomized controlled trials.

Our findings suggest that patients could see some benefit from using high-dose biotin over a period of 12 to 15 months.

However, it's important to note that this potential upside comes with a notable downside: an increased likelihood of affecting laboratory test results.

Overall, the evidence remains moderately certain, indicating a cautious approach is necessary for those considering biotin treatment for multiple sclerosis.

9.5

Stronger hair growth

Most Useful Review

As a cancer and COVID-19 survivor, I faced severe hair loss. After starting Biotin, my hair started to grow back stronger and fuller after two weeks. It helped reduce the brittleness I experienced post-COVID-19, making me feel secure in using this supplement.