Overview

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
USERS' SCORE
Good
Based on 9 Reviews
8.8
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%

Top Medical Research Studies

8
Iron's impact on migraine relief
We examined the link between iron deficiency anemia and migraines to understand how iron levels affect migraine symptoms. Our research confirmed that individuals suffering from migraines, especially women, tend to have lower iron levels. This suggests a significant relationship where low iron may worsen migraine frequency and intensity.

Through our literature review, we discovered that iron supplementation has been beneficial for some migraine sufferers, particularly those with diagnosed iron deficiency anemia. By increasing iron levels, we noted improvements in migraine symptoms, making it a potential treatment strategy worth considering.

However, we also highlighted that while iron supplementation shows promise, it’s essential to approach treatment carefully. Further research is necessary to determine the long-term effects and to establish guidelines on its use, minimizing any risks of iron overload. Overall, we advocate for incorporating nutritional evaluations into migraine management strategies to enhance patient outcomes effectively.
Read More
We investigated how dietary iron intake and serum ferritin levels relate to severe headaches and migraines in American adults. This research drew on data from 7,880 adults, aged 20 and above, collected between 1999 and 2004 as part of the National Health and Nutrition Examination Surveys (NHANES).

Our findings were particularly interesting for women aged 20 to 50 years, who generally consumed less iron than recommended. We observed that higher dietary iron intake in this group was linked to a lower occurrence of severe headaches or migraines. On the other hand, for women over 50, we discovered that greater serum ferritin levels—essentially a marker of iron storage—seemed to be associated with fewer migraine incidents.

However, for men, we found no significant connection between dietary iron and migraines. This suggests that the link between iron and migraines might be influenced by different biological factors, particularly hormonal changes in women related to menstrual cycles.

Overall, our results highlight the importance of proper dietary iron intake for women, especially those in their childbearing years, as it may help prevent severe headaches. For older women, maintaining higher ferritin levels could provide some protection against migraines as well.
Read More
7
Iron deficiency anemia and migraines
We set out to understand the relationship between iron deficiency anemia and migraine attacks. This study involved a case-control design, where we compared migraine sufferers with healthy individuals who did not have migraines or anemia, except for iron deficiency. Each group had at least 100 participants, allowing us to examine how iron levels influenced migraine incidents.

Our findings revealed that in females, there were significant differences in hemoglobin and serum ferritin levels when comparing those with migraines and those without. This suggests that low iron levels might be linked to more frequent or severe migraine attacks in women. However, we found no significant differences in iron levels or anemia among male participants.

Interestingly, while the study suggested an association between iron deficiency anemia and migraine severity in females, we also observed that treatment efforts or prophylactic measures, such as iron supplements, may hold potential benefits for women experiencing migraines associated with anemia. Still, we recognized that more research is needed to draw firm conclusions and clarify any remaining questions about this connection.
Read More

Most Useful Reviews

10
Eliminated migraines completely
Before starting these capsules, I had my ferritin level checked, which was at 11.2 ng/ml. Two months later, after taking one pill a day with 500mg of Vitamin C, I've noticed a significant improvement and my migraines have completely disappeared!
Read More
9.5
Decreased headache frequency
After giving birth, I consistently suffered from migraine headaches. However, after taking this supplement steadily for over a month, my headache frequency has decreased significantly.
Read More
9.5
Alleviates migraine symptoms
For my period symptoms, I always take this supplement as it really helps alleviate my migraine. I was previously diagnosed with low red blood cell levels, and I believe it benefits me greatly. Other brands upset my stomach.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
  • All Researches
8
Iron's impact on migraine relief
We examined the link between iron deficiency anemia and migraines to understand how iron levels affect migraine symptoms. Our research confirmed that individuals suffering from migraines, especially women, tend to have lower iron levels. This suggests a significant relationship where low iron may worsen migraine frequency and intensity.

Through our literature review, we discovered that iron supplementation has been beneficial for some migraine sufferers, particularly those with diagnosed iron deficiency anemia. By increasing iron levels, we noted improvements in migraine symptoms, making it a potential treatment strategy worth considering.

However, we also highlighted that while iron supplementation shows promise, it’s essential to approach treatment carefully. Further research is necessary to determine the long-term effects and to establish guidelines on its use, minimizing any risks of iron overload. Overall, we advocate for incorporating nutritional evaluations into migraine management strategies to enhance patient outcomes effectively.
Read More
We investigated how dietary iron intake and serum ferritin levels relate to severe headaches and migraines in American adults. This research drew on data from 7,880 adults, aged 20 and above, collected between 1999 and 2004 as part of the National Health and Nutrition Examination Surveys (NHANES).

Our findings were particularly interesting for women aged 20 to 50 years, who generally consumed less iron than recommended. We observed that higher dietary iron intake in this group was linked to a lower occurrence of severe headaches or migraines. On the other hand, for women over 50, we discovered that greater serum ferritin levels—essentially a marker of iron storage—seemed to be associated with fewer migraine incidents.

However, for men, we found no significant connection between dietary iron and migraines. This suggests that the link between iron and migraines might be influenced by different biological factors, particularly hormonal changes in women related to menstrual cycles.

Overall, our results highlight the importance of proper dietary iron intake for women, especially those in their childbearing years, as it may help prevent severe headaches. For older women, maintaining higher ferritin levels could provide some protection against migraines as well.
Read More
7
Iron deficiency anemia and migraines
We set out to understand the relationship between iron deficiency anemia and migraine attacks. This study involved a case-control design, where we compared migraine sufferers with healthy individuals who did not have migraines or anemia, except for iron deficiency. Each group had at least 100 participants, allowing us to examine how iron levels influenced migraine incidents.

Our findings revealed that in females, there were significant differences in hemoglobin and serum ferritin levels when comparing those with migraines and those without. This suggests that low iron levels might be linked to more frequent or severe migraine attacks in women. However, we found no significant differences in iron levels or anemia among male participants.

Interestingly, while the study suggested an association between iron deficiency anemia and migraine severity in females, we also observed that treatment efforts or prophylactic measures, such as iron supplements, may hold potential benefits for women experiencing migraines associated with anemia. Still, we recognized that more research is needed to draw firm conclusions and clarify any remaining questions about this connection.
Read More
We explored the potential link between iron levels in the brain and migraine attacks through a series of MRI scans. By looking at measures of brain iron content and white matter structure in a 26-year-old male migraine patient over 21 days, including both migraine-free days and days of attacks, we aimed to understand how iron might fluctuate during these episodes.

Our findings revealed interesting patterns: we observed that iron content in the brain changes during the migraine cycle. Specifically, there was an increase in white matter iron levels during migraine attacks. Alongside this, we noticed a decrease in the anisotropic properties of the brain tissue, suggesting that there might be additional changes happening in the brain's vascular system during these painful episodes.

While these results provide insights into how iron may play a role in migraine, it is important to note that the study does not confirm any direct benefits of iron treatment on migraines. Our work highlights the complexities of migraine pathology, but the direct impact of iron management remains unclear at this stage.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Eliminated migraines completely
Before starting these capsules, I had my ferritin level checked, which was at 11.2 ng/ml. Two months later, after taking one pill a day with 500mg of Vitamin C, I've noticed a significant improvement and my migraines have completely disappeared!
Read More
9.5
Decreased headache frequency
After giving birth, I consistently suffered from migraine headaches. However, after taking this supplement steadily for over a month, my headache frequency has decreased significantly.
Read More
9.5
Alleviates migraine symptoms
For my period symptoms, I always take this supplement as it really helps alleviate my migraine. I was previously diagnosed with low red blood cell levels, and I believe it benefits me greatly. Other brands upset my stomach.
Read More
8.8
Reduced migraines significantly
It is hard without this. I read reviews stating the headache was gone, so I took it for a trial, and it certainly reduced my migraine. My feet were often clogged and I struggled to sleep, but it improved with this. Initially, I was hesitant due to the common issue of iron supplements causing constipation, but I started taking it nearly a year ago. It is an essential supplement for me.
Read More
8.8
Less frequent migraines
The result is confirmed by analyses. This medication was recommended by my doctor who looked at both hemoglobin and ferritin, which was slightly below 20 for me. Three months of taking it with vitamin C raised my ferritin to 56. I noticed subjectively that my migraines have become less intriguing, and I also experienced improvements such as reduced tingling in my extremities and decreased hair loss. This medication was essential, and I've stocked up on it now.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Birkl C, Filippi V, Steiger R, Frank F, Magnesius S, et al. Dynamic fluctuations in brain iron content during migraine attacks: insights from relaxometry and diffusion tensor imaging. Front Neurol. 2024;15:1422313. doi:10.3389/fneur.2024.1422313
  2. Al-Qassab ZM, Ahmed O, Kannan V, Ullah N, Geddada S, et al. Iron Deficiency Anemia and Migraine: A Literature Review of the Prevalence, Pathophysiology, and Therapeutic Potential. Cureus. 2024;16:e69652. doi:10.7759/cureus.69652
  3. Meng SH, Zhou HB, Li X, Wang MX, Kang LX, et al. Association Between Dietary Iron Intake and Serum Ferritin and Severe Headache or Migraine. Front Nutr. 2021;8:685564. doi:10.3389/fnut.2021.685564
  4. Tayyebi A, Poursadeghfard M, Nazeri M, Pousadeghfard T. Is There Any Correlation between Migraine Attacks and Iron Deficiency Anemia? A Case-Control Study. Int J Hematol Oncol Stem Cell Res. 2019;13:164.
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