Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
USERS' SCORE
Good
Based on 6 Reviews
8.6
Supplement Facts
Serving Size: 5 Tablets
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
10 mcg (400 IU)
50%
Calcium (as calcium citrate)
1,000 mg
77%
Magnesium (as magnesium oxide, magnesium citrate)
500 mg
119%
Sodium
20 mg
<1%

Top Medical Research Studies

9
Magnesium improves elderly insomnia
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
We studied how high-dose vitamin D3 supplementation might affect insomnia in adolescent girls. Over nine weeks, 940 participants received a weekly dose of 50,000 IU of vitamin D3 while we tracked changes in their sleep patterns.

Interestingly, we observed a notable reduction in insomnia rates after the treatment. The number of girls reporting insomnia dropped from 15.0% to 11.3%, indicating that this vitamin can potentially improve sleep quality.

We also noticed a slight decrease in daytime sleepiness, with cases falling from 15.6% to 14.7%. Furthermore, those experiencing both insomnia and sleepiness saw a decline from 8.0% to 6.1%.

These findings suggest that high-dose vitamin D can play a significant role in alleviating sleep issues among adolescent girls. However, further studies are needed to see if these effects are consistent across diverse age and gender groups.
Read More
4
Magnesium shows limited sleep benefits
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.

We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.

Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
Read More

Most Useful Reviews

9
Insomnia relief
It significantly helps with insomnia!!!
Read More
9
Effective combination
I purchased this product due to its efficacy for insomnia. I often resort to coffee, which leads to calcium deficiency and insomnia, but after seeing the improvements, I decided to try this product. It seems to be the perfect combination for coffee drinkers.
Read More
9
Sleep normalised
Excellent! A remarkable product that aids in falling asleep and normalising sleep patterns. I bid farewell to insomnia, with the added benefit of vitamin D.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 14 Researches
7.6
  • All Researches
9
Vitamin D improves insomnia symptoms
We aimed to understand how vitamin D, specifically in the form of 1,500 IU nano-encapsulated vitamin D fortified in dairy products, could influence insomnia symptoms and quality of life. By conducting a case series, we selected 29 adults suffering from insomnia, particularly those with abdominal obesity. They were divided into four groups receiving different treatments over the course of 10 weeks: fortified low-fat milk, unfortified simple milk, fortified low-fat yogurt, and unfortified yogurt.

After analyzing the results, we found that participants consuming the vitamin D fortified milk experienced significant improvements in their insomnia symptoms compared to those drinking unfortified milk. However, those consuming fortified or unfortified yogurt showed no notable difference. Additionally, both groups consuming milk—fortified and simple—reported enhanced quality of life, although this was not observed in the yogurt groups.

Overall, our findings suggest that low-fat milk with added vitamin D can be beneficial for alleviating insomnia symptoms and improving quality of life, confirming its potential therapeutic role in sleep disorders.
Read More
9
Vitamin D3 effects on insomnia unclear
We conducted a controlled study to understand the effects of vitamin D3, along with other components, on insomnia and other symptoms experienced by menopausal women. Over 24 weeks, participants took either a formulation that included vitamin D3 or a standard calcium and vitamin D3 supplement.

Throughout the study, we tracked various symptoms like insomnia and mood changes. We found that while the formulation containing vitamin D3 showed some promise for addressing hormonal symptoms such as hot flashes and mood disturbances, the specific impact of vitamin D3 on insomnia was not isolated enough to draw definitive conclusions.

Importantly, participants who took the formulation reported improvements in overall well-being and satisfaction compared to those on regular calcium and vitamin D3. However, determining the isolated benefits of vitamin D3 alone remains challenging, as it was part of a broader mix of ingredients aimed at alleviating multiple menopause-related symptoms.

Thus, while our findings highlight the potential benefits of a comprehensive approach, the role of vitamin D3 specifically on insomnia is still uncertain. Further studies would be needed to clarify its effectiveness.
Read More
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.

At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.

Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.

The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.

However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More

User Reviews

USERS' SCORE
Good
Based on 6 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Insomnia relief
It significantly helps with insomnia!!!
Read More
9
Effective combination
I purchased this product due to its efficacy for insomnia. I often resort to coffee, which leads to calcium deficiency and insomnia, but after seeing the improvements, I decided to try this product. It seems to be the perfect combination for coffee drinkers.
Read More
9
Sleep normalised
Excellent! A remarkable product that aids in falling asleep and normalising sleep patterns. I bid farewell to insomnia, with the added benefit of vitamin D.
Read More
9
Easily falls asleep
Highly recommended! We take one tablet after dinner. The large package will last a long time. It helps you fall asleep easily without insomnia. Calcium is absorbed well with magnesium. I feel better overall, and even my nails have improved.
Read More
9
Natural solution
Compared to sleeping pills, nutrient supplementation is less likely to create addiction issues. For insomnia caused by stress and fatigue, it can help relieve neuromuscular tension consistently with physiological mechanisms, supplying the body with necessary electrolytes for natural relaxation. This drug-free approach is suitable for sensitive groups such as pregnant women and effectively addresses insomnia non-pharmacologically. Adequate magnesium supplementation is beneficial for mood stabilisation, muscle relaxation, and alleviating tension, significantly enhancing sleep quality through calcium and magnesium support.
Read More

Frequently Asked Questions

9
Sleep normalised
Excellent! A remarkable product that aids in falling asleep and normalising sleep patterns. I bid farewell to insomnia, with the added benefit of vitamin D.
7.5
Tiredness eased
The delivery was swift, and I'm excited to keep using it! Although I haven't tried it yet, I feel less tired, and my insomnia has disappeared. It's quite a refreshing feeling!
9
Natural solution
Compared to sleeping pills, nutrient supplementation is less likely to create addiction issues. For insomnia caused by stress and fatigue, it can help relieve neuromuscular tension consistently with physiological mechanisms, supplying the body with necessary electrolytes for natural relaxation. This drug-free approach is suitable for sensitive groups such as pregnant women and effectively addresses insomnia non-pharmacologically. Adequate magnesium supplementation is beneficial for mood stabilisation, muscle relaxation, and alleviating tension, significantly enhancing sleep quality through calcium and magnesium support.
9
Effective combination
I purchased this product due to its efficacy for insomnia. I often resort to coffee, which leads to calcium deficiency and insomnia, but after seeing the improvements, I decided to try this product. It seems to be the perfect combination for coffee drinkers.
9
Easily falls asleep
Highly recommended! We take one tablet after dinner. The large package will last a long time. It helps you fall asleep easily without insomnia. Calcium is absorbed well with magnesium. I feel better overall, and even my nails have improved.
We studied how high-dose vitamin D3 supplementation might affect insomnia in adolescent girls. Over nine weeks, 940 participants received a weekly dose of 50,000 IU of vitamin D3 while we tracked changes in their sleep patterns.

Interestingly, we observed a notable reduction in insomnia rates after the treatment. The number of girls reporting insomnia dropped from 15.0% to 11.3%, indicating that this vitamin can potentially improve sleep quality.

We also noticed a slight decrease in daytime sleepiness, with cases falling from 15.6% to 14.7%. Furthermore, those experiencing both insomnia and sleepiness saw a decline from 8.0% to 6.1%.

These findings suggest that high-dose vitamin D can play a significant role in alleviating sleep issues among adolescent girls. However, further studies are needed to see if these effects are consistent across diverse age and gender groups.
9
Vitamin D improves insomnia symptoms
We aimed to understand how vitamin D, specifically in the form of 1,500 IU nano-encapsulated vitamin D fortified in dairy products, could influence insomnia symptoms and quality of life. By conducting a case series, we selected 29 adults suffering from insomnia, particularly those with abdominal obesity. They were divided into four groups receiving different treatments over the course of 10 weeks: fortified low-fat milk, unfortified simple milk, fortified low-fat yogurt, and unfortified yogurt.

After analyzing the results, we found that participants consuming the vitamin D fortified milk experienced significant improvements in their insomnia symptoms compared to those drinking unfortified milk. However, those consuming fortified or unfortified yogurt showed no notable difference. Additionally, both groups consuming milk—fortified and simple—reported enhanced quality of life, although this was not observed in the yogurt groups.

Overall, our findings suggest that low-fat milk with added vitamin D can be beneficial for alleviating insomnia symptoms and improving quality of life, confirming its potential therapeutic role in sleep disorders.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.

A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.

However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.

Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
9
Magnesium improves elderly insomnia
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.

Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.

The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.

Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Magnesium may aid post-surgery insomnia
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.

We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.

This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.

While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.

References

  1. Bahrami A, Rezaeitalab F, Farahmand SK, Mazloum Khorasani Z, Arabi SM, et al. High-dose Vitamin D Supplementation and Improvement in Cognitive Abilities, Insomnia, and Daytime Sleepiness in Adolescent Girls. Basic Clin Neurosci. 2021;12:339. doi:10.32598/bcn.2021.1910.1
  2. Sharifan P, Khoshakhlagh M, Khorasanchi Z, Darroudi S, Rezaie M, et al. Efficacy of low-fat milk and yogurt fortified with encapsulated vitamin D on improvement in symptoms of insomnia and quality of life: Evidence from the SUVINA trial. Food Sci Nutr. 2020;8:4484. doi:10.1002/fsn3.1750
  3. Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
  4. Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. doi:10.3389/fendo.2024.1370733
  5. Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. doi:10.1186/s12871-024-02579-6
  6. Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. doi:10.7759/cureus.59317
  7. Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. doi:10.1186/s12906-021-03297-z
  8. Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. doi:10.3889/oamjms.2019.771
  9. Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. doi:10.3390/nu10101354
  10. Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. doi:10.3390/nu9020154
  11. Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
  12. Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. doi:10.1111/j.1532-5415.2010.03232.x
  13. Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
  14. Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.
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