Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
USERS' SCORE
Good
Based on 4 Reviews
8.6
Supplement Facts
Serving Size: 2 Vegetable Capsules
Amount Per Serving
%DV
Choline (as choline bitartrate)
500 mg
91%
Inositol
500 mg
**
Top Medical Research Studies
8
Myo-inositol: Depression treatment potential
We explored the potential of inositol, particularly Myo-inositol (MI), as a treatment option for depression, especially in individuals dealing with neurodegenerative disorders. The literature suggests that MI and its derivatives are vital in various cellular functions, including signal transmission and osmoregulation.
While our focus was primarily on neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, the interesting twist is how inositol may also help alleviate depressive symptoms. Research indicates that dietary supplementation with MI can have promising effects on mental health, suggesting a connection between inositol levels and mood enhancement.
However, despite the encouraging findings, much remains to be discovered. The relationship between inositol treatment and its effectiveness in treating depression is still being closely examined. Overall, it appears that while inositol shows potential, more comprehensive studies are needed to fully understand its benefits and mechanisms related specifically to depression.
While our focus was primarily on neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, the interesting twist is how inositol may also help alleviate depressive symptoms. Research indicates that dietary supplementation with MI can have promising effects on mental health, suggesting a connection between inositol levels and mood enhancement.
However, despite the encouraging findings, much remains to be discovered. The relationship between inositol treatment and its effectiveness in treating depression is still being closely examined. Overall, it appears that while inositol shows potential, more comprehensive studies are needed to fully understand its benefits and mechanisms related specifically to depression.
Read More
8
We conducted a detailed analysis of the effects of myo-inositol, alongside cocoa polyphenols and soy isoflavones, on managing symptoms of depression in menopausal women with metabolic syndrome.
In this study, 200 participants were observed over a six-month period while taking a daily supplement. At the beginning, many reported moderate depression symptoms. After six months, we noted a significant reduction, with only 56% of women reporting similar symptoms compared to 87% at the start.
This improvement in mood is quite promising and suggests that myo-inositol can play a key role in alleviating depressive symptoms during menopause. While the study focused on a specific group of women, the results indicate a potential for using natural compounds to ease their struggles.
In this study, 200 participants were observed over a six-month period while taking a daily supplement. At the beginning, many reported moderate depression symptoms. After six months, we noted a significant reduction, with only 56% of women reporting similar symptoms compared to 87% at the start.
This improvement in mood is quite promising and suggests that myo-inositol can play a key role in alleviating depressive symptoms during menopause. While the study focused on a specific group of women, the results indicate a potential for using natural compounds to ease their struggles.
Read More
8
Inositol's role in depression unclear
We explored the role of inositol in alleviating depression among children and adolescents. This systematic review gathered data from nine studies involving 561 participants, focusing on the effectiveness of omega-3 fatty acids alongside inositol in combating depressive symptoms.
Our analysis found that while inositol is often included with omega-3 in combination therapies, its isolated effect on depression could not be clearly established. The results indicated that when omega-3 is combined with inositol, it showed promising efficacy, acting as a potential support for traditional therapies.
However, we noted that there was no significant improvement in depression symptoms compared to placebo treatments when evaluating these interventions individually. Ultimately, omega-3 paired with psychoeducational psychotherapy emerged as the most effective approach, but the impact of inositol on its own remains inconclusive.
These findings suggest a need for future studies to assess inositol individually, helping us better understand its potential in managing depression.
Our analysis found that while inositol is often included with omega-3 in combination therapies, its isolated effect on depression could not be clearly established. The results indicated that when omega-3 is combined with inositol, it showed promising efficacy, acting as a potential support for traditional therapies.
However, we noted that there was no significant improvement in depression symptoms compared to placebo treatments when evaluating these interventions individually. Ultimately, omega-3 paired with psychoeducational psychotherapy emerged as the most effective approach, but the impact of inositol on its own remains inconclusive.
These findings suggest a need for future studies to assess inositol individually, helping us better understand its potential in managing depression.
Read More
Most Useful Reviews
9
Reduced anxiety significantly
29 people found this helpful
Wonderful! Verified helps! I took 2 capsules a day once. After just 2 weeks, I noted a significant reduction in anxiety and panic attacks. After 1 month of taking it, my depression and the resulting apathy diminished considerably. The medication works gently without sudden fluctuations. I combined it with ginkgo biloba, which enhanced my clarity of thought. Additionally, the choline in this product aids liver recovery. I trust Solgar, and this product has not let me down.
Read More
9
Apathy significantly reduced
6 people found this helpful
I took 2 capsules daily. Within 2 weeks, I noticed my anxiety and panic attacks lessening. After a month, both my depression and related apathy significantly diminished. The drug acts gently without sudden changes. I combined it with ginkgo biloba, and my thinking improved—clarity returned. Furthermore, the choline helps in liver restoration. I trust Solgar, and this product did not disappoint.
Read More
7.5
Positive mood improvement
4 people found this helpful
Choline (250 mg) and inositol (250 mg) in a capsule can positively affect brain function and mood. Choline enhances memory and cognitive ability, while inositol may improve mood and alleviate anxiety, particularly in those suffering from depression. We've been taking 1 capsule daily, gradually increasing to 2-4 as needed. The brand Solgar is excellent—I've trusted it for many supplements before.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 4 Researches
7
- All Researches
8
Inositol's role in depression unclear
We explored the role of inositol in alleviating depression among children and adolescents. This systematic review gathered data from nine studies involving 561 participants, focusing on the effectiveness of omega-3 fatty acids alongside inositol in combating depressive symptoms.
Our analysis found that while inositol is often included with omega-3 in combination therapies, its isolated effect on depression could not be clearly established. The results indicated that when omega-3 is combined with inositol, it showed promising efficacy, acting as a potential support for traditional therapies.
However, we noted that there was no significant improvement in depression symptoms compared to placebo treatments when evaluating these interventions individually. Ultimately, omega-3 paired with psychoeducational psychotherapy emerged as the most effective approach, but the impact of inositol on its own remains inconclusive.
These findings suggest a need for future studies to assess inositol individually, helping us better understand its potential in managing depression.
Our analysis found that while inositol is often included with omega-3 in combination therapies, its isolated effect on depression could not be clearly established. The results indicated that when omega-3 is combined with inositol, it showed promising efficacy, acting as a potential support for traditional therapies.
However, we noted that there was no significant improvement in depression symptoms compared to placebo treatments when evaluating these interventions individually. Ultimately, omega-3 paired with psychoeducational psychotherapy emerged as the most effective approach, but the impact of inositol on its own remains inconclusive.
These findings suggest a need for future studies to assess inositol individually, helping us better understand its potential in managing depression.
Read More
8
We conducted a detailed analysis of the effects of myo-inositol, alongside cocoa polyphenols and soy isoflavones, on managing symptoms of depression in menopausal women with metabolic syndrome.
In this study, 200 participants were observed over a six-month period while taking a daily supplement. At the beginning, many reported moderate depression symptoms. After six months, we noted a significant reduction, with only 56% of women reporting similar symptoms compared to 87% at the start.
This improvement in mood is quite promising and suggests that myo-inositol can play a key role in alleviating depressive symptoms during menopause. While the study focused on a specific group of women, the results indicate a potential for using natural compounds to ease their struggles.
In this study, 200 participants were observed over a six-month period while taking a daily supplement. At the beginning, many reported moderate depression symptoms. After six months, we noted a significant reduction, with only 56% of women reporting similar symptoms compared to 87% at the start.
This improvement in mood is quite promising and suggests that myo-inositol can play a key role in alleviating depressive symptoms during menopause. While the study focused on a specific group of women, the results indicate a potential for using natural compounds to ease their struggles.
Read More
8
Myo-inositol: Depression treatment potential
We explored the potential of inositol, particularly Myo-inositol (MI), as a treatment option for depression, especially in individuals dealing with neurodegenerative disorders. The literature suggests that MI and its derivatives are vital in various cellular functions, including signal transmission and osmoregulation.
While our focus was primarily on neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, the interesting twist is how inositol may also help alleviate depressive symptoms. Research indicates that dietary supplementation with MI can have promising effects on mental health, suggesting a connection between inositol levels and mood enhancement.
However, despite the encouraging findings, much remains to be discovered. The relationship between inositol treatment and its effectiveness in treating depression is still being closely examined. Overall, it appears that while inositol shows potential, more comprehensive studies are needed to fully understand its benefits and mechanisms related specifically to depression.
While our focus was primarily on neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, the interesting twist is how inositol may also help alleviate depressive symptoms. Research indicates that dietary supplementation with MI can have promising effects on mental health, suggesting a connection between inositol levels and mood enhancement.
However, despite the encouraging findings, much remains to be discovered. The relationship between inositol treatment and its effectiveness in treating depression is still being closely examined. Overall, it appears that while inositol shows potential, more comprehensive studies are needed to fully understand its benefits and mechanisms related specifically to depression.
Read More
4
No significant effect on depression
We explored the impact of a specific blend of myo-inositol, probiotics, and micronutrients on mental health for women planning for conception and during pregnancy. In a double-blind randomized controlled trial involving over 600 participants, we assessed mental wellbeing through recognized scales both during pregnancy and after childbirth. Our aim was to find out if this supplement could improve mood and reduce anxiety levels.
While we monitored changes in mood and anxiety symptoms using standardized questionnaires, the results showed no significant differences between the group taking the supplement and the control group receiving standard micronutrients. This indicates that, at least in this study, the combined supplement did not appear to have a notable effect on lowering depression or anxiety during pregnancy.
However, we did find a small improvement in overall mental health functioning, as measured by the Short-Form Health Survey, from preconception to six months post-delivery for those in the intervention group. This suggests that while myo-inositol and its companions may not directly impact mood and anxiety, there could be some beneficial effects on broader mental health after delivery.
While we monitored changes in mood and anxiety symptoms using standardized questionnaires, the results showed no significant differences between the group taking the supplement and the control group receiving standard micronutrients. This indicates that, at least in this study, the combined supplement did not appear to have a notable effect on lowering depression or anxiety during pregnancy.
However, we did find a small improvement in overall mental health functioning, as measured by the Short-Form Health Survey, from preconception to six months post-delivery for those in the intervention group. This suggests that while myo-inositol and its companions may not directly impact mood and anxiety, there could be some beneficial effects on broader mental health after delivery.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Reduced anxiety significantly
29 people found this helpful
Wonderful! Verified helps! I took 2 capsules a day once. After just 2 weeks, I noted a significant reduction in anxiety and panic attacks. After 1 month of taking it, my depression and the resulting apathy diminished considerably. The medication works gently without sudden fluctuations. I combined it with ginkgo biloba, which enhanced my clarity of thought. Additionally, the choline in this product aids liver recovery. I trust Solgar, and this product has not let me down.
Read More
9
Apathy significantly reduced
6 people found this helpful
I took 2 capsules daily. Within 2 weeks, I noticed my anxiety and panic attacks lessening. After a month, both my depression and related apathy significantly diminished. The drug acts gently without sudden changes. I combined it with ginkgo biloba, and my thinking improved—clarity returned. Furthermore, the choline helps in liver restoration. I trust Solgar, and this product did not disappoint.
Read More
7.5
Positive mood improvement
4 people found this helpful
Choline (250 mg) and inositol (250 mg) in a capsule can positively affect brain function and mood. Choline enhances memory and cognitive ability, while inositol may improve mood and alleviate anxiety, particularly in those suffering from depression. We've been taking 1 capsule daily, gradually increasing to 2-4 as needed. The brand Solgar is excellent—I've trusted it for many supplements before.
Read More
9
Helpful for depression
GREAT PRODUCT! It helped me immensely in combination with St. John's wort in managing my depression.
Read More
Frequently Asked Questions
9
Reduced anxiety significantly
29 people found this helpful
Wonderful! Verified helps! I took 2 capsules a day once. After just 2 weeks, I noted a significant reduction in anxiety and panic attacks. After 1 month of taking it, my depression and the resulting apathy diminished considerably. The medication works gently without sudden fluctuations. I combined it with ginkgo biloba, which enhanced my clarity of thought. Additionally, the choline in this product aids liver recovery. I trust Solgar, and this product has not let me down.
9
Apathy significantly reduced
6 people found this helpful
I took 2 capsules daily. Within 2 weeks, I noticed my anxiety and panic attacks lessening. After a month, both my depression and related apathy significantly diminished. The drug acts gently without sudden changes. I combined it with ginkgo biloba, and my thinking improved—clarity returned. Furthermore, the choline helps in liver restoration. I trust Solgar, and this product did not disappoint.
7.5
Positive mood improvement
4 people found this helpful
Choline (250 mg) and inositol (250 mg) in a capsule can positively affect brain function and mood. Choline enhances memory and cognitive ability, while inositol may improve mood and alleviate anxiety, particularly in those suffering from depression. We've been taking 1 capsule daily, gradually increasing to 2-4 as needed. The brand Solgar is excellent—I've trusted it for many supplements before.
9
Helpful for depression
GREAT PRODUCT! It helped me immensely in combination with St. John's wort in managing my depression.
8
Inositol's role in depression unclear
We explored the role of inositol in alleviating depression among children and adolescents. This systematic review gathered data from nine studies involving 561 participants, focusing on the effectiveness of omega-3 fatty acids alongside inositol in combating depressive symptoms.
Our analysis found that while inositol is often included with omega-3 in combination therapies, its isolated effect on depression could not be clearly established. The results indicated that when omega-3 is combined with inositol, it showed promising efficacy, acting as a potential support for traditional therapies.
However, we noted that there was no significant improvement in depression symptoms compared to placebo treatments when evaluating these interventions individually. Ultimately, omega-3 paired with psychoeducational psychotherapy emerged as the most effective approach, but the impact of inositol on its own remains inconclusive.
These findings suggest a need for future studies to assess inositol individually, helping us better understand its potential in managing depression.
Our analysis found that while inositol is often included with omega-3 in combination therapies, its isolated effect on depression could not be clearly established. The results indicated that when omega-3 is combined with inositol, it showed promising efficacy, acting as a potential support for traditional therapies.
However, we noted that there was no significant improvement in depression symptoms compared to placebo treatments when evaluating these interventions individually. Ultimately, omega-3 paired with psychoeducational psychotherapy emerged as the most effective approach, but the impact of inositol on its own remains inconclusive.
These findings suggest a need for future studies to assess inositol individually, helping us better understand its potential in managing depression.
8
We conducted a detailed analysis of the effects of myo-inositol, alongside cocoa polyphenols and soy isoflavones, on managing symptoms of depression in menopausal women with metabolic syndrome.
In this study, 200 participants were observed over a six-month period while taking a daily supplement. At the beginning, many reported moderate depression symptoms. After six months, we noted a significant reduction, with only 56% of women reporting similar symptoms compared to 87% at the start.
This improvement in mood is quite promising and suggests that myo-inositol can play a key role in alleviating depressive symptoms during menopause. While the study focused on a specific group of women, the results indicate a potential for using natural compounds to ease their struggles.
In this study, 200 participants were observed over a six-month period while taking a daily supplement. At the beginning, many reported moderate depression symptoms. After six months, we noted a significant reduction, with only 56% of women reporting similar symptoms compared to 87% at the start.
This improvement in mood is quite promising and suggests that myo-inositol can play a key role in alleviating depressive symptoms during menopause. While the study focused on a specific group of women, the results indicate a potential for using natural compounds to ease their struggles.
4
No significant effect on depression
We explored the impact of a specific blend of myo-inositol, probiotics, and micronutrients on mental health for women planning for conception and during pregnancy. In a double-blind randomized controlled trial involving over 600 participants, we assessed mental wellbeing through recognized scales both during pregnancy and after childbirth. Our aim was to find out if this supplement could improve mood and reduce anxiety levels.
While we monitored changes in mood and anxiety symptoms using standardized questionnaires, the results showed no significant differences between the group taking the supplement and the control group receiving standard micronutrients. This indicates that, at least in this study, the combined supplement did not appear to have a notable effect on lowering depression or anxiety during pregnancy.
However, we did find a small improvement in overall mental health functioning, as measured by the Short-Form Health Survey, from preconception to six months post-delivery for those in the intervention group. This suggests that while myo-inositol and its companions may not directly impact mood and anxiety, there could be some beneficial effects on broader mental health after delivery.
While we monitored changes in mood and anxiety symptoms using standardized questionnaires, the results showed no significant differences between the group taking the supplement and the control group receiving standard micronutrients. This indicates that, at least in this study, the combined supplement did not appear to have a notable effect on lowering depression or anxiety during pregnancy.
However, we did find a small improvement in overall mental health functioning, as measured by the Short-Form Health Survey, from preconception to six months post-delivery for those in the intervention group. This suggests that while myo-inositol and its companions may not directly impact mood and anxiety, there could be some beneficial effects on broader mental health after delivery.
8
Myo-inositol: Depression treatment potential
We explored the potential of inositol, particularly Myo-inositol (MI), as a treatment option for depression, especially in individuals dealing with neurodegenerative disorders. The literature suggests that MI and its derivatives are vital in various cellular functions, including signal transmission and osmoregulation.
While our focus was primarily on neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, the interesting twist is how inositol may also help alleviate depressive symptoms. Research indicates that dietary supplementation with MI can have promising effects on mental health, suggesting a connection between inositol levels and mood enhancement.
However, despite the encouraging findings, much remains to be discovered. The relationship between inositol treatment and its effectiveness in treating depression is still being closely examined. Overall, it appears that while inositol shows potential, more comprehensive studies are needed to fully understand its benefits and mechanisms related specifically to depression.
While our focus was primarily on neurodegenerative diseases like Alzheimer's, Parkinson's, and Huntington's, the interesting twist is how inositol may also help alleviate depressive symptoms. Research indicates that dietary supplementation with MI can have promising effects on mental health, suggesting a connection between inositol levels and mood enhancement.
However, despite the encouraging findings, much remains to be discovered. The relationship between inositol treatment and its effectiveness in treating depression is still being closely examined. Overall, it appears that while inositol shows potential, more comprehensive studies are needed to fully understand its benefits and mechanisms related specifically to depression.
References
- Lam C, Han L, McIntyre RS, Teopiz KM, Cao B. Comparative Efficacy of Omega-3 Fatty Acid with Other Interventions for Depression in Children and Adolescents: A Systematic Review and Network Meta-Analysis. J Child Adolesc Psychopharmacol. 2024;34:282. doi:10.1089/cap.2024.0017
- Mainini G, Ercolano S, De Simone R, Iavarone I, Lizza R, et al. Dietary Supplementation of Myo-Inositol, Cocoa Polyphenols, and Soy Isoflavones Improves Vasomotor Symptoms and Metabolic Profile in Menopausal Women with Metabolic Syndrome: A Retrospective Clinical Study. Medicina (Kaunas). 2024;60. doi:10.3390/medicina60040598
- El-Heis S, Barton SJ, Chang HF, Nield H, Cox V, et al. Maternal mood, anxiety and mental health functioning after combined myo-inositol, probiotics, micronutrient supplementation from preconception: Findings from the NiPPeR RCT. Psychiatry Res. 2024;334:115813. doi:10.1016/j.psychres.2024.115813
- Derkaczew M, Martyniuk P, Osowski A, Wojtkiewicz J. Cyclitols: From Basic Understanding to Their Association with Neurodegeneration. Nutrients. 2023;15. doi:10.3390/nu15092029
