Last update
5/10/2026

Overview

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.7
USERS' SCORE
Moderately Good
Based on 141 Reviews
7.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil (Seed) providing:
1300 mg
***
Linoleic Acid
949 mg
***
Gamma-Linolenic Acid
117 mg
***
📅 Last updated:

Top Medical Research Studies

We explored the effects of evening primrose oil on menopausal hot flashes in a 6-week clinical trial involving 56 women aged 45-59. Participants received either evening primrose or a placebo and reported their hot flash experiences using a specific questionnaire.

While both groups showed improvement, evening primrose oil notably reduced the severity of hot flashes compared to placebo. Specific improvements were also found in social interactions and sexuality for those taking evening primrose, making it a promising option for managing hot flash symptoms.
Read More
4
Evening primrose oil lacks efficacy
We explored the effectiveness of evening primrose oil (EPO) as a treatment for hot flashes in menopausal women. Following rigorous systematic reviews and randomized trials, we discovered that while EPO showed some reduction in hot flash severity after less than six months, it did not significantly improve the frequency or duration of these symptoms compared to a placebo. Some participants did report mild nausea and headache. Ultimately, the evidence remains inconclusive, leaving us hopeful for further studies on EPO's potential benefits.
Read More
4
Meta-analysis shows limited EPO effectiveness
We examined six randomized controlled trials involving 450 women to assess whether evening primrose oil (EPO) could help manage hot flashes during menopause. Women taking EPO experienced a modest decrease of about 2 fewer hot flashes per day compared to those receiving a placebo, though this difference wasn't statistically significant.

The picture became clearer when we looked at hot flash duration—EPO did produce a meaningful reduction here. However, when measuring hot flash intensity on a scale, the improvement was minimal and not statistically significant. Overall, the evidence quality was rated as moderate to low, suggesting we need larger, more rigorously designed studies before drawing firm conclusions about EPO's true effectiveness for hot flashes.
Read More

Most Useful Reviews

10
Effective relief
8 people found this helpful
Hot flash miracle. Hot flashes NO MORE! If you suffer from hot flashes and want relief, this product works wonders. I take two every morning, and it keeps them at bay.
Read More
9
Effective relief
8 people found this helpful
Great stuff for menopausal women! I’ve been taking it for about two years, and I can confidently say it alleviates most of my hot flashes. If I miss taking it for a few days, they return, proving its effectiveness against my "personal summers."
Read More
7.5
Horrible hot flashes reduced
7 people found this helpful
It works! I was experiencing horrible hot flashes, but this product, alongside black cohosh, has helped me immensely. I now have just a few hot flashes each day.
Read More

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Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 7 Researches
5.7
  • All Researches
9
Evening primrose oil reduces hot flashes
We investigated how evening primrose oil, as part of the Exelvit Menopause® nutritional product, affects menopausal symptoms, including hot flashes. In a study of 156 menopausal women, participants took the product daily for 12 weeks.

The results showed a significant reduction in hot flashes by 48.15%, along with improvements in other symptoms like sleep disturbances and anxiety. This evidence suggests that evening primrose oil may be a beneficial option for managing menopausal discomfort.
Read More
9
Evening primrose oil aids menopausal symptoms
We examined the effects of a proprietary blend of herbs, including evening primrose oil, on menopausal symptoms in post-menopausal women. Using a randomized, double-blind, placebo-controlled trial design, 101 women participated in the study over 12 weeks. Our findings revealed significant reductions in hot flashes, sweating, sleep issues, and mood disturbances in the treatment group compared to the placebo. While hormone levels showed no significant change, improvements in health indicators were noted. Overall, this combination of four herbs appears to effectively support women through their menopausal transition.
Read More
We explored the effects of evening primrose oil on menopausal hot flashes in a 6-week clinical trial involving 56 women aged 45-59. Participants received either evening primrose or a placebo and reported their hot flash experiences using a specific questionnaire.

While both groups showed improvement, evening primrose oil notably reduced the severity of hot flashes compared to placebo. Specific improvements were also found in social interactions and sexuality for those taking evening primrose, making it a promising option for managing hot flash symptoms.
Read More
4
Evening primrose oil lacks efficacy
We explored the effectiveness of evening primrose oil (EPO) as a treatment for hot flashes in menopausal women. Following rigorous systematic reviews and randomized trials, we discovered that while EPO showed some reduction in hot flash severity after less than six months, it did not significantly improve the frequency or duration of these symptoms compared to a placebo. Some participants did report mild nausea and headache. Ultimately, the evidence remains inconclusive, leaving us hopeful for further studies on EPO's potential benefits.
Read More
4
Mixed evidence for evening primrose oil
We explored the effects of evening primrose oil (EPO), derived from Oenothera biennis, on various inflammatory conditions through a systematic review of randomized controlled trials. While we found some evidence supporting EPO's benefits for certain disorders like rheumatoid arthritis and menopausal hot flashes, mixed results were common and many conditions showed no significant improvement.

The overall findings highlighted a lack of strong recommendations for EPO due to variations in study results and a need for more high-quality research to clarify its effectiveness in managing inflammatory symptoms.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 141 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Effective relief
8 people found this helpful
Hot flash miracle. Hot flashes NO MORE! If you suffer from hot flashes and want relief, this product works wonders. I take two every morning, and it keeps them at bay.
Read More
9
Effective relief
8 people found this helpful
Great stuff for menopausal women! I’ve been taking it for about two years, and I can confidently say it alleviates most of my hot flashes. If I miss taking it for a few days, they return, proving its effectiveness against my "personal summers."
Read More
7.5
Horrible hot flashes reduced
7 people found this helpful
It works! I was experiencing horrible hot flashes, but this product, alongside black cohosh, has helped me immensely. I now have just a few hot flashes each day.
Read More
10
Hot flashes eliminated
6 people found this helpful
Highly recommend! At 49, I started experiencing hot flashes, both during the day and at night. I eagerly awaited the availability of this drug and, after just four days of use, the hot flashes disappeared completely. My sleep improved significantly, and I've been using it for the second month with additional benefits such as reduced hair loss. I recommend this product for improving your health at the first signs of menopause!
Read More
10
Highly recommended relief
6 people found this helpful
This product is essential for every menopausal woman suffering from hot flashes. It completely stopped my hot flashes! My doctor recommended it for my menopausal hot flashes, and it works!
Read More

Frequently Asked Questions

10
Hot flashes eliminated
6 people found this helpful
Highly recommend! At 49, I started experiencing hot flashes, both during the day and at night. I eagerly awaited the availability of this drug and, after just four days of use, the hot flashes disappeared completely. My sleep improved significantly, and I've been using it for the second month with additional benefits such as reduced hair loss. I recommend this product for improving your health at the first signs of menopause!
9
Diminished intensity
1 people found this helpful
Good buy! This really helped me with my hot flashes. My face used to sweat excessively, but since I started using this regularly, it now just feels like a blush. The intensity has diminished, and I no longer experience them daily.
9
No more flashes
1 people found this helpful
I'm in love with this. It's a very large pill, but that's alright. I've been taking it for a month and I haven't had hot flashes or any ups and downs during my period.
10
Hormonal balance
4 people found this helpful
My wife regularly takes this product, and after three months, I see its effectiveness. She experienced a stabilisation in her hormonal background, and her hot flashes entirely disappeared, improving her skin condition significantly.
9
Effective relief
8 people found this helpful
Great stuff for menopausal women! I’ve been taking it for about two years, and I can confidently say it alleviates most of my hot flashes. If I miss taking it for a few days, they return, proving its effectiveness against my "personal summers."
9
Stopped symptoms quickly
2 people found this helpful
I am 25 and suffer from hormone imbalance. After starting this, my hot flashes and night sweats ceased within a week. This product is excellent and I will definitely repurchase it!
8
Overall health improved
1 people found this helpful
Evening primrose oil effectively alleviates hot flashes in menopausal women, reducing their severity, frequency, and duration. A study showed participants not only experienced relief from hot flashes but also improved social interactions and sexual well-being. Overall health and the quality of hair and nails also improved.
9
Effective for hot flashes
3 people found this helpful
This oil worked wonders for my premenopausal symptoms. My hot flashes decreased to 1-2 per day and then completely disappeared. It also improved my sleep, making me feel well-rested.
9
Symptoms disappeared
1 people found this helpful
Super supplement! I've been on hormone replacement therapy for years, but when the dosage was reduced, hot flashes began, affecting my sleep. After one week of taking evening primrose oil with Maca, my hormone deficiency symptoms gradually faded. After three weeks, everything had resolved, and I will definitely continue taking it.
4
Evening primrose oil lacks efficacy
We explored the effectiveness of evening primrose oil (EPO) as a treatment for hot flashes in menopausal women. Following rigorous systematic reviews and randomized trials, we discovered that while EPO showed some reduction in hot flash severity after less than six months, it did not significantly improve the frequency or duration of these symptoms compared to a placebo. Some participants did report mild nausea and headache. Ultimately, the evidence remains inconclusive, leaving us hopeful for further studies on EPO's potential benefits.
9
Evening primrose oil reduces hot flashes
We investigated how evening primrose oil, as part of the Exelvit Menopause® nutritional product, affects menopausal symptoms, including hot flashes. In a study of 156 menopausal women, participants took the product daily for 12 weeks.

The results showed a significant reduction in hot flashes by 48.15%, along with improvements in other symptoms like sleep disturbances and anxiety. This evidence suggests that evening primrose oil may be a beneficial option for managing menopausal discomfort.
We looked into how evening primrose oil (EPO) affects hot flashes in postmenopausal women. In our study, 80 women were divided into two groups; one received EPO while the other took black cohosh over 8 weeks. Both groups reported reduced severity of hot flashes and improved quality of life. However, the black cohosh group saw a significant decrease in the number of hot flashes, while EPO did not show significant improvements. This suggests that while EPO may help alleviate symptoms, black cohosh appears to be more effective overall.
4
Mixed evidence for evening primrose oil
We explored the effects of evening primrose oil (EPO), derived from Oenothera biennis, on various inflammatory conditions through a systematic review of randomized controlled trials. While we found some evidence supporting EPO's benefits for certain disorders like rheumatoid arthritis and menopausal hot flashes, mixed results were common and many conditions showed no significant improvement.

The overall findings highlighted a lack of strong recommendations for EPO due to variations in study results and a need for more high-quality research to clarify its effectiveness in managing inflammatory symptoms.

References

  1. Thevi T, De S, Soe HHK. Evening Primrose Oil for Menopause Hot Flashes: Systematic Review and Meta-Analysis. J Menopausal Med. 2024;30:127. 10.6118/jmm.23038
  2. Sharifi M, Nourani N, Sanaie S, Hamedeyazdan S. The effect of Oenothera biennis (Evening primrose) oil on inflammatory diseases: a systematic review of clinical trials. BMC Complement Med Ther. 2024;24:89. 10.1186/s12906-024-04378-5
  3. Palacios S, Mustata C, Rizo JM, Regidor PA. Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9. Eur Rev Med Pharmacol Sci. 2023;27:8180. 10.26355/eurrev_202309_33578
  4. Rattanatantikul T, Maiprasert M, Sugkraroek P, Bumrungpert A. Efficacy and Safety of Nutraceutical on Menopausal Symptoms in Post-Menopausal Women: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. J Diet Suppl. 2022;19:168. 10.1080/19390211.2020.1853648
  5. Mehrpooya M, Rabiee S, Larki-Harchegani A, Fallahian AM, Moradi A, et al. A comparative study on the effect of "black cohosh" and "evening primrose oil" on menopausal hot flashes. J Educ Health Promot. 2018;7:36. 10.4103/jehp.jehp_81_17
  6. Farzaneh F, Fatehi S, Sohrabi MR, Alizadeh K. The effect of oral evening primrose oil on menopausal hot flashes: a randomized clinical trial. Arch Gynecol Obstet. 2013;288:1075. 10.1007/s00404-013-2852-6
  7. Larki M, Mohammadi S, Makvandi S. The Effect of Evening Primrose Oil on Menopausal Symptoms Management: A Systematic Review and Meta-Analysis. J Caring Sci. 2025;14:293. 10.34172/jcs.025.33570
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