Last update
3/8/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7
USERS' SCORE
Questionable
Based on 26 Reviews
5.9
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Polyunsaturated Fat
1 g
***
Evening Primrose Oil (Seed) providing:
1300 mg
***
Linoleic Acid
949 mg
***
Gamma-Linolenic Acid
117 mg
***
Top Medical Research Studies
9
We conducted a double-blinded, placebo-controlled trial to assess evening primrose oil's effects on psychological symptoms in postmenopausal women. Participants received either 1,000 mg of evening primrose oil or a placebo for 8 weeks.
Our findings indicated a significant reduction in psychological symptoms among those taking evening primrose oil compared to the placebo group. Specifically, the intervention group showed a notable improvement in their scores.
While promising, we recognize that further research is needed to fully validate these benefits and ensure the long-term safety of evening primrose oil in clinical practice.
Our findings indicated a significant reduction in psychological symptoms among those taking evening primrose oil compared to the placebo group. Specifically, the intervention group showed a notable improvement in their scores.
While promising, we recognize that further research is needed to fully validate these benefits and ensure the long-term safety of evening primrose oil in clinical practice.
Read More
8
We investigated how evening primrose oil affects psychological symptoms in menopausal women through a triple-blind, randomized clinical trial. The study included 100 women who received either evening primrose oil or a placebo.
We found that those using evening primrose oil experienced significant reductions in psychological symptoms, as measured by the Menopause Rating Scale, while the placebo group showed no improvement.
This suggests that evening primrose oil may be beneficial in enhancing the quality of life for postmenopausal women by alleviating psychological distress.
We found that those using evening primrose oil experienced significant reductions in psychological symptoms, as measured by the Menopause Rating Scale, while the placebo group showed no improvement.
This suggests that evening primrose oil may be beneficial in enhancing the quality of life for postmenopausal women by alleviating psychological distress.
Read More
7
We explored the effects of evening primrose oil (EPO) and fennel on menopausal symptoms and hormone levels, using a triple-blinded method with 125 participants over 8 weeks.
While both EPO and fennel showed significant changes in hormone levels compared to a placebo, the impact on psychological menopausal symptoms was not notably different between the two groups after treatment.
In the end, neither oil proved to be more effective than the other for alleviating menopause-related issues.
While both EPO and fennel showed significant changes in hormone levels compared to a placebo, the impact on psychological menopausal symptoms was not notably different between the two groups after treatment.
In the end, neither oil proved to be more effective than the other for alleviating menopause-related issues.
Read More
Most Useful Reviews
0
Body resistance
123 people found this helpful
Although this supplement has a good composition, it did not suit me during menopause. I hoped it would help balance my body but faced resistance. I’ll return to WomenSense instead.
Read More
9
Better sleep aid
32 people found this helpful
This product works for me. After using it for over six months, I find it helps me sleep due to my menopause symptoms. I take one in the morning and one at night; it doesn't make me drowsy during the day. Everyone has different sensitivities, so I recommend trying it. It takes time to feel results, but I'm relieved not to resort to hormonal treatments.
Read More
10
Amazing transformation
18 people found this helpful
I started taking two every morning, and the change was truly amazing. I felt like my old self again after struggling with focus, irritability, and moodiness during menopause. This is one of the two supplements I would never give up.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 10 Researches
7
- All Researches
9
Evening primrose oil reduces menopause symptoms
We examined the effectiveness and safety of Exelvit Menopause®, a nutritional product featuring evening primrose oil, among 156 menopausal women over 12 weeks. This study showed a notable decrease in various menopausal symptoms.
Participants experienced improvements, such as a 48% reduction in hot flashes and 46% in sleep disturbances. Symptoms like irritability and anxiety also decreased significantly. These results suggest that evening primrose oil can help alleviate menopause-related discomfort effectively.
Participants experienced improvements, such as a 48% reduction in hot flashes and 46% in sleep disturbances. Symptoms like irritability and anxiety also decreased significantly. These results suggest that evening primrose oil can help alleviate menopause-related discomfort effectively.
Read More
9
We conducted a double-blinded, placebo-controlled trial to assess evening primrose oil's effects on psychological symptoms in postmenopausal women. Participants received either 1,000 mg of evening primrose oil or a placebo for 8 weeks.
Our findings indicated a significant reduction in psychological symptoms among those taking evening primrose oil compared to the placebo group. Specifically, the intervention group showed a notable improvement in their scores.
While promising, we recognize that further research is needed to fully validate these benefits and ensure the long-term safety of evening primrose oil in clinical practice.
Our findings indicated a significant reduction in psychological symptoms among those taking evening primrose oil compared to the placebo group. Specifically, the intervention group showed a notable improvement in their scores.
While promising, we recognize that further research is needed to fully validate these benefits and ensure the long-term safety of evening primrose oil in clinical practice.
Read More
8
We investigated how evening primrose oil affects psychological symptoms in menopausal women through a triple-blind, randomized clinical trial. The study included 100 women who received either evening primrose oil or a placebo.
We found that those using evening primrose oil experienced significant reductions in psychological symptoms, as measured by the Menopause Rating Scale, while the placebo group showed no improvement.
This suggests that evening primrose oil may be beneficial in enhancing the quality of life for postmenopausal women by alleviating psychological distress.
We found that those using evening primrose oil experienced significant reductions in psychological symptoms, as measured by the Menopause Rating Scale, while the placebo group showed no improvement.
This suggests that evening primrose oil may be beneficial in enhancing the quality of life for postmenopausal women by alleviating psychological distress.
Read More
8
We investigated the effectiveness of Lady 4, a natural remedy containing evening primrose oil and other ingredients, on menopausal symptoms in women.
In a study of 120 women, half received Lady 4, while the others took a placebo. We measured the results using a specific scale for menopause symptoms.
The findings showed a significant improvement in those taking Lady 4 compared to the placebo group, with many participants feeling much better. This suggests that Lady 4 could be a helpful option for managing menopausal symptoms.
In a study of 120 women, half received Lady 4, while the others took a placebo. We measured the results using a specific scale for menopause symptoms.
The findings showed a significant improvement in those taking Lady 4 compared to the placebo group, with many participants feeling much better. This suggests that Lady 4 could be a helpful option for managing menopausal symptoms.
Read More
7
We explored the effects of evening primrose oil (EPO) and fennel on menopausal symptoms and hormone levels, using a triple-blinded method with 125 participants over 8 weeks.
While both EPO and fennel showed significant changes in hormone levels compared to a placebo, the impact on psychological menopausal symptoms was not notably different between the two groups after treatment.
In the end, neither oil proved to be more effective than the other for alleviating menopause-related issues.
While both EPO and fennel showed significant changes in hormone levels compared to a placebo, the impact on psychological menopausal symptoms was not notably different between the two groups after treatment.
In the end, neither oil proved to be more effective than the other for alleviating menopause-related issues.
Read More
User Reviews
USERS' SCORE
Questionable
Based on 26 Reviews
5.9
- All Reviews
- Positive Reviews
- Negative Reviews
0
Body resistance
123 people found this helpful
Although this supplement has a good composition, it did not suit me during menopause. I hoped it would help balance my body but faced resistance. I’ll return to WomenSense instead.
Read More
9
Better sleep aid
32 people found this helpful
This product works for me. After using it for over six months, I find it helps me sleep due to my menopause symptoms. I take one in the morning and one at night; it doesn't make me drowsy during the day. Everyone has different sensitivities, so I recommend trying it. It takes time to feel results, but I'm relieved not to resort to hormonal treatments.
Read More
10
Amazing transformation
18 people found this helpful
I started taking two every morning, and the change was truly amazing. I felt like my old self again after struggling with focus, irritability, and moodiness during menopause. This is one of the two supplements I would never give up.
Read More
9
Essential support
9 people found this helpful
Great brand. These make a difference if you are going through menopause! I couldn't live without them! They help with PMS, sleep, headaches, and hot flashes.
Read More
7.5
Alleviates night sweats
6 people found this helpful
This product assists with menopause symptoms when taken alongside soy and black Cohosh. It helps alleviate night sweats and other discomforts related to menopause.
Read More
Frequently Asked Questions
0
Body resistance
123 people found this helpful
Although this supplement has a good composition, it did not suit me during menopause. I hoped it would help balance my body but faced resistance. I’ll return to WomenSense instead.
4
Evening primrose oil shows limited effectiveness
We explored the effects of evening primrose oil (EPO) as a treatment for menopausal hot flashes through a systematic review of various clinical trials.
While we found that EPO reduced the severity of hot flashes when taken for under six months, it did not significantly impact the frequency or duration compared to a placebo.
Some participants reported mild side effects like nausea and headaches, and EPO did not perform better than black cohosh in longer periods.
Ultimately, the evidence remains inconclusive regarding EPO's effectiveness for hot flashes, highlighting the need for further studies.
While we found that EPO reduced the severity of hot flashes when taken for under six months, it did not significantly impact the frequency or duration compared to a placebo.
Some participants reported mild side effects like nausea and headaches, and EPO did not perform better than black cohosh in longer periods.
Ultimately, the evidence remains inconclusive regarding EPO's effectiveness for hot flashes, highlighting the need for further studies.
9
Evening primrose oil reduces menopause symptoms
We examined the effectiveness and safety of Exelvit Menopause®, a nutritional product featuring evening primrose oil, among 156 menopausal women over 12 weeks. This study showed a notable decrease in various menopausal symptoms.
Participants experienced improvements, such as a 48% reduction in hot flashes and 46% in sleep disturbances. Symptoms like irritability and anxiety also decreased significantly. These results suggest that evening primrose oil can help alleviate menopause-related discomfort effectively.
Participants experienced improvements, such as a 48% reduction in hot flashes and 46% in sleep disturbances. Symptoms like irritability and anxiety also decreased significantly. These results suggest that evening primrose oil can help alleviate menopause-related discomfort effectively.
4
We assessed how evening primrose oil (EPO) and black cohosh impact menopausal hot flashes in a study with 80 postmenopausal women. Participants were divided into two groups, with one taking EPO and the other black cohosh for 8 weeks.
While both supplements improved hot flash severity and quality of life, the results showed that black cohosh was more effective. It significantly reduced both the severity and number of hot flashes, whereas EPO only improved severity without a change in the number of flashes.
While both supplements improved hot flash severity and quality of life, the results showed that black cohosh was more effective. It significantly reduced both the severity and number of hot flashes, whereas EPO only improved severity without a change in the number of flashes.
9
We conducted a double-blinded, placebo-controlled trial to assess evening primrose oil's effects on psychological symptoms in postmenopausal women. Participants received either 1,000 mg of evening primrose oil or a placebo for 8 weeks.
Our findings indicated a significant reduction in psychological symptoms among those taking evening primrose oil compared to the placebo group. Specifically, the intervention group showed a notable improvement in their scores.
While promising, we recognize that further research is needed to fully validate these benefits and ensure the long-term safety of evening primrose oil in clinical practice.
Our findings indicated a significant reduction in psychological symptoms among those taking evening primrose oil compared to the placebo group. Specifically, the intervention group showed a notable improvement in their scores.
While promising, we recognize that further research is needed to fully validate these benefits and ensure the long-term safety of evening primrose oil in clinical practice.
References
- Thevi T, De S, Soe HHK. Evening Primrose Oil for Menopause Hot Flashes: Systematic Review and Meta-Analysis. J Menopausal Med. 2024;30:127. 10.6118/jmm.23038
- Palacios S, Mustata C, Rizo JM, Regidor PA. Improvement in menopausal symptoms with a nutritional product containing evening primrose oil, hop extract, saffron, tryptophan, vitamins B6, D3, K2, B12, and B9. Eur Rev Med Pharmacol Sci. 2023;27:8180. 10.26355/eurrev_202309_33578
- Ghavi F, Shakeri F, Farahnaz H, Abdolahian S. Comparison of the Effect of Fennel and Evening Primrose Oil on Menopausal Problems and Hormonal Levels: A Randomized Controlled Trial. Iran J Nurs Midwifery Res. 2023;28:430. 10.4103/ijnmr.ijnmr_149_22
- Safdari F, Motaghi Dastenaei B, Kheiri S, Karimiankakolaki Z. Effect of Evening Primrose Oil on Postmenopausal Psychological Symptoms: A Triple-Blind Randomized Clinical Trial. J Menopausal Med. 2021;27:58. 10.6118/jmm.21010
- Kazemi F, Masoumi SZ, Shayan A, Oshvandi K. The Effect of Evening Primrose Oil Capsule on Hot Flashes and Night Sweats in Postmenopausal Women: A Single-Blind Randomized Controlled Trial. J Menopausal Med. 2021;27:8. 10.6118/jmm.20033
- Sharif SN, Darsareh F. Impact of evening primrose oil consumption on psychological symptoms of postmenopausal women: a randomized double-blinded placebo-controlled clinical trial. Menopause. 2020;27:194. 10.1097/GME.0000000000001434
- Mehrpooya M, Rabiee S, Larki-Harchegani A, Fallahian AM, Moradi A, et al. A comparative study on the effect of "black cohosh" and "evening primrose oil" on menopausal hot flashes. J Educ Health Promot. 2018;7:36. 10.4103/jehp.jehp_81_17
- Ohn Mar S, Malhi F, Syed Rahim SH, Chua CT, Sidhu SS, et al. Use of Alternative Medications for Menopause-Related Symptoms in Three Major Ethnic Groups of Ipoh, Perak, Malaysia. Asia Pac J Public Health. 2015;27:19S. 10.1177/1010539515586457
- Yakoot M, Salem A, Omar AM. Effectiveness of a herbal formula in women with menopausal syndrome. Forsch Komplementmed. 2011;18:264. 10.1159/000333430
- van der Sluijs CP, Bensoussan A, Liyanage L, Shah S. Women's health during mid-life survey: the use of complementary and alternative medicine by symptomatic women transitioning through menopause in Sydney. Menopause. 2007;14:397. PubMed
Data last updated:
