' 
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
USERS' SCORE
Good
Based on 1 Review
8.5
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
8
Serum ferritin levels affect GDM
The association between serum ferritin levels and the risk of gestational diabetes mellitus: a prospective cohort study.
Significant findings on iron impact
We conducted a comprehensive study involving over 10,000 pregnant women to explore how serum ferritin levels—the stored form of iron in our bodies—might influence the risk of gestational diabetes mellitus (GDM). Serum ferritin levels were measured during the first and second trimesters, and women were subsequently tested for GDM between 24 to 28 weeks of pregnancy.
Our findings revealed that serum ferritin levels do play a role in the risk of developing GDM. Specifically, we found that women with lower ferritin levels in the first trimester who experienced an increase in levels by the second trimester had a significantly higher risk for GDM. Likewise, those who maintained high ferritin levels throughout both trimesters also showed increased risk.
These results suggest that maintaining a balanced level of iron in the body during early pregnancy may help reduce the chances of developing GDM. While our study highlights the importance of iron metabolism, it does not focus exclusively on the effects of iron treatment, leaving some questions open about how targeted iron therapies might influence diabetes risk directly.
Overall, understanding the connection between iron metabolism and diabetes is crucial as it can guide preventative strategies for expectant mothers.
Our findings revealed that serum ferritin levels do play a role in the risk of developing GDM. Specifically, we found that women with lower ferritin levels in the first trimester who experienced an increase in levels by the second trimester had a significantly higher risk for GDM. Likewise, those who maintained high ferritin levels throughout both trimesters also showed increased risk.
These results suggest that maintaining a balanced level of iron in the body during early pregnancy may help reduce the chances of developing GDM. While our study highlights the importance of iron metabolism, it does not focus exclusively on the effects of iron treatment, leaving some questions open about how targeted iron therapies might influence diabetes risk directly.
Overall, understanding the connection between iron metabolism and diabetes is crucial as it can guide preventative strategies for expectant mothers.
Read More
4
Red wine affects iron in diabetes
Red wine consumption activates the erythropoietin-erythroferrone-hepcidin erythropoietic pathway in both apparently healthy individuals and patients with type 2 diabetes.
Focus on wine and diabetes
We explored the effects of red wine on iron regulation and its potential influence on individuals with type 2 diabetes. In our study, we had participants consume 300 ml of red wine daily for three weeks, following a two-week alcohol-free period. We observed that this consumption led to a decrease in serum hepcidin, a hormone critical for iron regulation, in both healthy individuals and those with type 2 diabetes.
Accompanying this decrease in hepcidin, we found an increase in erythropoietin levels across both groups. Particularly in the diabetes group, erythroferrone levels also rose significantly. Importantly, these changes hinted at activation of the erythropoietin-erythroferrone-hepcidin pathway, which is fundamental in the body's iron management.
We also noted changes in red cell distribution width and higher reticulocyte counts in the diabetes group, alongside decreased levels of serum ferritin. Our findings reveal that red wine may play a unique role in managing iron levels, which can be crucial for those with diabetes and conditions affecting iron homeostasis. While more research is needed, this study highlights a fascinating connection between dietary choices and metabolic health.
Accompanying this decrease in hepcidin, we found an increase in erythropoietin levels across both groups. Particularly in the diabetes group, erythroferrone levels also rose significantly. Importantly, these changes hinted at activation of the erythropoietin-erythroferrone-hepcidin pathway, which is fundamental in the body's iron management.
We also noted changes in red cell distribution width and higher reticulocyte counts in the diabetes group, alongside decreased levels of serum ferritin. Our findings reveal that red wine may play a unique role in managing iron levels, which can be crucial for those with diabetes and conditions affecting iron homeostasis. While more research is needed, this study highlights a fascinating connection between dietary choices and metabolic health.
Read More
7
Serum ferritin levels and GDM
A retrospective study of the correlation between high serum ferritin levels and the risk of gestational diabetes mellitus in midpregnant women.
Indirectly relates to diabetes treatment
We conducted a retrospective study focusing on the relationship between high serum ferritin levels and the risk of developing gestational diabetes mellitus (GDM) in pregnant women. Our research involved 1,052 women in their mid-pregnancy, specifically between 24 to 28 weeks of gestation.
The findings indicated that those with GDM tended to have higher levels of serum ferritin compared to those without the condition. While we observed a positive correlation between ferritin levels and one-hour glucose test results, an unexpected negative correlation appeared between ferritin and HbA1c levels.
Importantly, our analysis suggested that elevated ferritin levels could increase the risk of GDM, with adjusted odds showing a significant increase in risk after considering factors like age and body mass index. This suggests that managing iron levels during pregnancy might influence the likelihood of developing GDM, warranting further investigation through clinical trials.
However, it’s important to note that our study doesn’t directly evaluate iron treatment’s effectiveness on diabetes management, but provides groundwork for understanding how iron levels might relate to diabetes risks during pregnancy.
The findings indicated that those with GDM tended to have higher levels of serum ferritin compared to those without the condition. While we observed a positive correlation between ferritin levels and one-hour glucose test results, an unexpected negative correlation appeared between ferritin and HbA1c levels.
Importantly, our analysis suggested that elevated ferritin levels could increase the risk of GDM, with adjusted odds showing a significant increase in risk after considering factors like age and body mass index. This suggests that managing iron levels during pregnancy might influence the likelihood of developing GDM, warranting further investigation through clinical trials.
However, it’s important to note that our study doesn’t directly evaluate iron treatment’s effectiveness on diabetes management, but provides groundwork for understanding how iron levels might relate to diabetes risks during pregnancy.
Read More
Most Useful Reviews
8
Constipation relief
My doctor prescribed me new diabetes medication that caused severe constipation. I started with two capsules, but it wasn't as effective as I'd hoped. After reading that some take four capsules, I decided to increase my intake to three, which did the trick.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 3 Researches
6.3
8
Serum ferritin levels affect GDM
The association between serum ferritin levels and the risk of gestational diabetes mellitus: a prospective cohort study.
Significant findings on iron impact
We conducted a comprehensive study involving over 10,000 pregnant women to explore how serum ferritin levels—the stored form of iron in our bodies—might influence the risk of gestational diabetes mellitus (GDM). Serum ferritin levels were measured during the first and second trimesters, and women were subsequently tested for GDM between 24 to 28 weeks of pregnancy.
Our findings revealed that serum ferritin levels do play a role in the risk of developing GDM. Specifically, we found that women with lower ferritin levels in the first trimester who experienced an increase in levels by the second trimester had a significantly higher risk for GDM. Likewise, those who maintained high ferritin levels throughout both trimesters also showed increased risk.
These results suggest that maintaining a balanced level of iron in the body during early pregnancy may help reduce the chances of developing GDM. While our study highlights the importance of iron metabolism, it does not focus exclusively on the effects of iron treatment, leaving some questions open about how targeted iron therapies might influence diabetes risk directly.
Overall, understanding the connection between iron metabolism and diabetes is crucial as it can guide preventative strategies for expectant mothers.
Our findings revealed that serum ferritin levels do play a role in the risk of developing GDM. Specifically, we found that women with lower ferritin levels in the first trimester who experienced an increase in levels by the second trimester had a significantly higher risk for GDM. Likewise, those who maintained high ferritin levels throughout both trimesters also showed increased risk.
These results suggest that maintaining a balanced level of iron in the body during early pregnancy may help reduce the chances of developing GDM. While our study highlights the importance of iron metabolism, it does not focus exclusively on the effects of iron treatment, leaving some questions open about how targeted iron therapies might influence diabetes risk directly.
Overall, understanding the connection between iron metabolism and diabetes is crucial as it can guide preventative strategies for expectant mothers.
Read More
7
Serum ferritin levels and GDM
A retrospective study of the correlation between high serum ferritin levels and the risk of gestational diabetes mellitus in midpregnant women.
Indirectly relates to diabetes treatment
We conducted a retrospective study focusing on the relationship between high serum ferritin levels and the risk of developing gestational diabetes mellitus (GDM) in pregnant women. Our research involved 1,052 women in their mid-pregnancy, specifically between 24 to 28 weeks of gestation.
The findings indicated that those with GDM tended to have higher levels of serum ferritin compared to those without the condition. While we observed a positive correlation between ferritin levels and one-hour glucose test results, an unexpected negative correlation appeared between ferritin and HbA1c levels.
Importantly, our analysis suggested that elevated ferritin levels could increase the risk of GDM, with adjusted odds showing a significant increase in risk after considering factors like age and body mass index. This suggests that managing iron levels during pregnancy might influence the likelihood of developing GDM, warranting further investigation through clinical trials.
However, it’s important to note that our study doesn’t directly evaluate iron treatment’s effectiveness on diabetes management, but provides groundwork for understanding how iron levels might relate to diabetes risks during pregnancy.
The findings indicated that those with GDM tended to have higher levels of serum ferritin compared to those without the condition. While we observed a positive correlation between ferritin levels and one-hour glucose test results, an unexpected negative correlation appeared between ferritin and HbA1c levels.
Importantly, our analysis suggested that elevated ferritin levels could increase the risk of GDM, with adjusted odds showing a significant increase in risk after considering factors like age and body mass index. This suggests that managing iron levels during pregnancy might influence the likelihood of developing GDM, warranting further investigation through clinical trials.
However, it’s important to note that our study doesn’t directly evaluate iron treatment’s effectiveness on diabetes management, but provides groundwork for understanding how iron levels might relate to diabetes risks during pregnancy.
Read More
4
Red wine affects iron in diabetes
Red wine consumption activates the erythropoietin-erythroferrone-hepcidin erythropoietic pathway in both apparently healthy individuals and patients with type 2 diabetes.
Focus on wine and diabetes
We explored the effects of red wine on iron regulation and its potential influence on individuals with type 2 diabetes. In our study, we had participants consume 300 ml of red wine daily for three weeks, following a two-week alcohol-free period. We observed that this consumption led to a decrease in serum hepcidin, a hormone critical for iron regulation, in both healthy individuals and those with type 2 diabetes.
Accompanying this decrease in hepcidin, we found an increase in erythropoietin levels across both groups. Particularly in the diabetes group, erythroferrone levels also rose significantly. Importantly, these changes hinted at activation of the erythropoietin-erythroferrone-hepcidin pathway, which is fundamental in the body's iron management.
We also noted changes in red cell distribution width and higher reticulocyte counts in the diabetes group, alongside decreased levels of serum ferritin. Our findings reveal that red wine may play a unique role in managing iron levels, which can be crucial for those with diabetes and conditions affecting iron homeostasis. While more research is needed, this study highlights a fascinating connection between dietary choices and metabolic health.
Accompanying this decrease in hepcidin, we found an increase in erythropoietin levels across both groups. Particularly in the diabetes group, erythroferrone levels also rose significantly. Importantly, these changes hinted at activation of the erythropoietin-erythroferrone-hepcidin pathway, which is fundamental in the body's iron management.
We also noted changes in red cell distribution width and higher reticulocyte counts in the diabetes group, alongside decreased levels of serum ferritin. Our findings reveal that red wine may play a unique role in managing iron levels, which can be crucial for those with diabetes and conditions affecting iron homeostasis. While more research is needed, this study highlights a fascinating connection between dietary choices and metabolic health.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.5
8
Constipation relief
My doctor prescribed me new diabetes medication that caused severe constipation. I started with two capsules, but it wasn't as effective as I'd hoped. After reading that some take four capsules, I decided to increase my intake to three, which did the trick.
