Overview

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
USERS' SCORE
Good
Based on 9 Reviews
8.8
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%

Top Medical Research Studies

8
Iron's impact on migraine relief
We examined the link between iron deficiency anemia and migraines to understand how iron levels affect migraine symptoms. Our research confirmed that individuals suffering from migraines, especially women, tend to have lower iron levels. This suggests a significant relationship where low iron may worsen migraine frequency and intensity.

Through our literature review, we discovered that iron supplementation has been beneficial for some migraine sufferers, particularly those with diagnosed iron deficiency anemia. By increasing iron levels, we noted improvements in migraine symptoms, making it a potential treatment strategy worth considering.

However, we also highlighted that while iron supplementation shows promise, it’s essential to approach treatment carefully. Further research is necessary to determine the long-term effects and to establish guidelines on its use, minimizing any risks of iron overload. Overall, we advocate for incorporating nutritional evaluations into migraine management strategies to enhance patient outcomes effectively.
Read More
We investigated how dietary iron intake and serum ferritin levels relate to severe headaches and migraines in American adults. This research drew on data from 7,880 adults, aged 20 and above, collected between 1999 and 2004 as part of the National Health and Nutrition Examination Surveys (NHANES).

Our findings were particularly interesting for women aged 20 to 50 years, who generally consumed less iron than recommended. We observed that higher dietary iron intake in this group was linked to a lower occurrence of severe headaches or migraines. On the other hand, for women over 50, we discovered that greater serum ferritin levels—essentially a marker of iron storage—seemed to be associated with fewer migraine incidents.

However, for men, we found no significant connection between dietary iron and migraines. This suggests that the link between iron and migraines might be influenced by different biological factors, particularly hormonal changes in women related to menstrual cycles.

Overall, our results highlight the importance of proper dietary iron intake for women, especially those in their childbearing years, as it may help prevent severe headaches. For older women, maintaining higher ferritin levels could provide some protection against migraines as well.
Read More
7
Iron deficiency anemia and migraines
We set out to understand the relationship between iron deficiency anemia and migraine attacks. This study involved a case-control design, where we compared migraine sufferers with healthy individuals who did not have migraines or anemia, except for iron deficiency. Each group had at least 100 participants, allowing us to examine how iron levels influenced migraine incidents.

Our findings revealed that in females, there were significant differences in hemoglobin and serum ferritin levels when comparing those with migraines and those without. This suggests that low iron levels might be linked to more frequent or severe migraine attacks in women. However, we found no significant differences in iron levels or anemia among male participants.

Interestingly, while the study suggested an association between iron deficiency anemia and migraine severity in females, we also observed that treatment efforts or prophylactic measures, such as iron supplements, may hold potential benefits for women experiencing migraines associated with anemia. Still, we recognized that more research is needed to draw firm conclusions and clarify any remaining questions about this connection.
Read More

Most Useful Reviews

10
Eliminated migraines completely
Before starting these capsules, I had my ferritin level checked, which was at 11.2 ng/ml. Two months later, after taking one pill a day with 500mg of Vitamin C, I've noticed a significant improvement and my migraines have completely disappeared!
Read More
9.5
Decreased headache frequency
After giving birth, I consistently suffered from migraine headaches. However, after taking this supplement steadily for over a month, my headache frequency has decreased significantly.
Read More
9.5
Alleviates migraine symptoms
For my period symptoms, I always take this supplement as it really helps alleviate my migraine. I was previously diagnosed with low red blood cell levels, and I believe it benefits me greatly. Other brands upset my stomach.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.8
  • All Researches
8
Iron's impact on migraine relief
We examined the link between iron deficiency anemia and migraines to understand how iron levels affect migraine symptoms. Our research confirmed that individuals suffering from migraines, especially women, tend to have lower iron levels. This suggests a significant relationship where low iron may worsen migraine frequency and intensity.

Through our literature review, we discovered that iron supplementation has been beneficial for some migraine sufferers, particularly those with diagnosed iron deficiency anemia. By increasing iron levels, we noted improvements in migraine symptoms, making it a potential treatment strategy worth considering.

However, we also highlighted that while iron supplementation shows promise, it’s essential to approach treatment carefully. Further research is necessary to determine the long-term effects and to establish guidelines on its use, minimizing any risks of iron overload. Overall, we advocate for incorporating nutritional evaluations into migraine management strategies to enhance patient outcomes effectively.
Read More
We investigated how dietary iron intake and serum ferritin levels relate to severe headaches and migraines in American adults. This research drew on data from 7,880 adults, aged 20 and above, collected between 1999 and 2004 as part of the National Health and Nutrition Examination Surveys (NHANES).

Our findings were particularly interesting for women aged 20 to 50 years, who generally consumed less iron than recommended. We observed that higher dietary iron intake in this group was linked to a lower occurrence of severe headaches or migraines. On the other hand, for women over 50, we discovered that greater serum ferritin levels—essentially a marker of iron storage—seemed to be associated with fewer migraine incidents.

However, for men, we found no significant connection between dietary iron and migraines. This suggests that the link between iron and migraines might be influenced by different biological factors, particularly hormonal changes in women related to menstrual cycles.

Overall, our results highlight the importance of proper dietary iron intake for women, especially those in their childbearing years, as it may help prevent severe headaches. For older women, maintaining higher ferritin levels could provide some protection against migraines as well.
Read More
7
Iron deficiency anemia and migraines
We set out to understand the relationship between iron deficiency anemia and migraine attacks. This study involved a case-control design, where we compared migraine sufferers with healthy individuals who did not have migraines or anemia, except for iron deficiency. Each group had at least 100 participants, allowing us to examine how iron levels influenced migraine incidents.

Our findings revealed that in females, there were significant differences in hemoglobin and serum ferritin levels when comparing those with migraines and those without. This suggests that low iron levels might be linked to more frequent or severe migraine attacks in women. However, we found no significant differences in iron levels or anemia among male participants.

Interestingly, while the study suggested an association between iron deficiency anemia and migraine severity in females, we also observed that treatment efforts or prophylactic measures, such as iron supplements, may hold potential benefits for women experiencing migraines associated with anemia. Still, we recognized that more research is needed to draw firm conclusions and clarify any remaining questions about this connection.
Read More
We explored the potential link between iron levels in the brain and migraine attacks through a series of MRI scans. By looking at measures of brain iron content and white matter structure in a 26-year-old male migraine patient over 21 days, including both migraine-free days and days of attacks, we aimed to understand how iron might fluctuate during these episodes.

Our findings revealed interesting patterns: we observed that iron content in the brain changes during the migraine cycle. Specifically, there was an increase in white matter iron levels during migraine attacks. Alongside this, we noticed a decrease in the anisotropic properties of the brain tissue, suggesting that there might be additional changes happening in the brain's vascular system during these painful episodes.

While these results provide insights into how iron may play a role in migraine, it is important to note that the study does not confirm any direct benefits of iron treatment on migraines. Our work highlights the complexities of migraine pathology, but the direct impact of iron management remains unclear at this stage.
Read More

User Reviews

USERS' SCORE
Good
Based on 9 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Eliminated migraines completely
Before starting these capsules, I had my ferritin level checked, which was at 11.2 ng/ml. Two months later, after taking one pill a day with 500mg of Vitamin C, I've noticed a significant improvement and my migraines have completely disappeared!
Read More
9.5
Decreased headache frequency
After giving birth, I consistently suffered from migraine headaches. However, after taking this supplement steadily for over a month, my headache frequency has decreased significantly.
Read More
9.5
Alleviates migraine symptoms
For my period symptoms, I always take this supplement as it really helps alleviate my migraine. I was previously diagnosed with low red blood cell levels, and I believe it benefits me greatly. Other brands upset my stomach.
Read More
8.8
Reduced migraines significantly
It is hard without this. I read reviews stating the headache was gone, so I took it for a trial, and it certainly reduced my migraine. My feet were often clogged and I struggled to sleep, but it improved with this. Initially, I was hesitant due to the common issue of iron supplements causing constipation, but I started taking it nearly a year ago. It is an essential supplement for me.
Read More
8.8
Less frequent migraines
The result is confirmed by analyses. This medication was recommended by my doctor who looked at both hemoglobin and ferritin, which was slightly below 20 for me. Three months of taking it with vitamin C raised my ferritin to 56. I noticed subjectively that my migraines have become less intriguing, and I also experienced improvements such as reduced tingling in my extremities and decreased hair loss. This medication was essential, and I've stocked up on it now.
Read More

Frequently Asked Questions

Migraine is a neurological condition characterized by recurrent and often debilitating headaches, typically accompanied by a variety of symptoms such as nausea, vomiting, and heightened sensitivity to light and sound. These headaches can be pulsing or throbbing in nature and are usually localized to one side of the head, although they can occur on both sides. Migraines can last anywhere from a few hours to several days and can significantly interfere with daily activities. Many individuals also experience an "aura," which can include visual disturbances like flashing lights or blind spots, as a precursor to the actual headache.

While the exact cause of migraines is not fully understood, they are thought to be linked to changes in brain activity and environmental factors, along with genetics. Various triggers can precipitate a migraine attack, including stress, hormonal changes, certain foods, and sleep disturbances. Treatment options vary and can include prescription medications, over-the-counter pain relief, lifestyle changes, and preventive strategies. If you suffer from migraines, it's essential to consult with a healthcare professional to develop a tailored management plan suited to your symptoms and needs.

Iron is a chemical element with the symbol Fe, derived from the Latin word "ferrum." It is a metal that is known for its strength and versatility, making it one of the most widely used materials in construction, manufacturing, and various industrial applications. Iron is the fourth most abundant element in the universe by mass and is primarily obtained through the mining of iron ores, such as hematite and magnetite. Once mined, it undergoes processes like smelting and refining to produce usable forms like cast iron, wrought iron, and steel.

In addition to its industrial uses, iron is also crucial for human health, as it plays a significant role in the production of hemoglobin, the protein in red blood cells responsible for transporting oxygen throughout the body. A deficiency in iron can lead to anemia, characterized by fatigue and weakened immunity. Overall, iron is a fundamental element that supports modern infrastructure and is vital for maintaining good health.

While iron is essential for overall health, its specific role in managing migraines is not well-established. Some studies have suggested that low levels of iron may be linked to increased headache frequency, including migraines. For individuals with iron deficiency, replenishing iron stores through diet or supplements could potentially reduce the occurrence of migraines as a secondary effect of improving overall health. However, it is important to note that any supplementation should be discussed with a healthcare provider, as excessive iron can lead to other health issues.

Additionally, migraines are complex and can be influenced by various factors, including dietary choices, lifestyle, and underlying health conditions. Therefore, focusing solely on iron intake might not address the root causes of migraine headaches. If you are experiencing frequent migraines, it is advisable to consult with a healthcare professional who can help determine the underlying causes and develop a comprehensive treatment plan tailored to your needs.

Based on user reviews, it appears that individuals experience varying timelines for seeing results with this supplement for migraines. Some users report noticeable improvements in just a couple of weeks. For instance, one reviewer mentioned that after starting the supplement, their migraines eased somewhat within two weeks of usage (Read Review). On the other hand, several reviewers indicate it may take about a month or more to experience significant relief. For example, another user noted a substantial decrease in headache frequency after consistently taking the supplement for over a month (Read Review).

Moreover, others have shared longer timelines of around two to three months before experiencing the full benefits, such as completely eliminating migraines (Read Review). This suggests that while some individuals may feel relief fairly quickly, others may need to adhere to the regimen for a longer duration to achieve optimal results. Overall, user experiences highlight the importance of consistency and patience when taking this supplement for migraine relief.

Recent research presents a nuanced picture regarding the use of iron supplementation for migraine management. A study found that individuals suffering from migraines, particularly women, often have lower iron levels, which suggests that low iron may worsen migraine frequency and intensity [2]. Notably, some evidence indicates that iron supplementation can alleviate migraine symptoms in individuals with diagnosed iron deficiency anemia, making it a treatment option worth considering [2]. However, it is essential to approach this treatment cautiously, as the long-term effects and appropriate guidelines for iron supplementation in migraine patients are still under investigation.

Further studies reinforce the idea that dietary iron intake is significantly related to migraine prevalence among specific populations, particularly younger women who tend to consume less iron than recommended [3]. Among studies exploring iron deficiency anemia and migraine connections, findings suggest that lower iron levels correlate with increased frequency and severity of migraine attacks in women [4]. Despite these positive correlations, the direct impact of iron supplementation as a comprehensive treatment for migraines lacks confirmation, highlighting the need for continued research to clarify its effectiveness [1]. Overall, while the association between iron and migraines is promising, further studies are necessary to establish clear guidelines for supplementation.

Based on user reviews, many individuals have reported significant improvements in their migraine symptoms after using this supplement. For instance, one user mentioned that after only two months of taking the supplement alongside Vitamin C, their migraines completely disappeared, indicating a remarkable turnaround in their condition (Read Review). Another person noticed a significant decrease in headache frequency after a month of consistent use following childbirth, exemplifying how this supplement can be particularly beneficial during transitions in life (Read Review).

Furthermore, several users linked their migraines to underlying iron deficiency and have shared positive anecdotal experiences of relief after incorporating this supplement into their routine. For example, one reviewer highlighted that their longstanding menstrual headaches almost vanished after starting iron supplementation (Read Review). Other users have reported improvements in related symptoms like tingling and hair loss alongside reduced migraine intensity, signifying that the benefits of this supplement can extend beyond just alleviating headaches (Read Review). As always, individual results may vary, but the consensus points toward this supplement being a valuable consideration for those struggling with migraines.

Based on user reviews, combining this supplement with other supplements, particularly Vitamin C, appears to enhance its effectiveness in managing migraines. For example, one reviewer experienced complete relief from migraines after taking this supplement daily along with 500mg of Vitamin C for two months (Read Review). Another user indicated that consistent use of this supplement had significantly reduced their migraine frequency following childbirth, highlighting its potential benefits during hormonal changes (Read Review).

Additionally, several reviews suggest that taking this supplement alongside other medications or dietary adjustments has led to notable improvements. One user highlighted that their migraines were closely linked to low iron levels and noted a marked decrease in headache intensity after starting iron supplementation (Read Review). Another mentioned improvements in both migraine symptoms and additional symptoms like tingling and hair loss after three months of combined use with Vitamin C (Read Review). Overall, users report positive experiences when combining this supplement with others to alleviate migraine symptoms.

Users report a variety of experiences when it comes to finding the right dose of iron for treating migraines. Several reviewers noted significant improvements in their migraine symptoms after taking iron supplements regularly. For instance, one user highlighted a complete disappearance of migraines after taking one pill daily with 500mg of Vitamin C for two months, retesting their ferritin levels (Read Review). Another user indicated that consistent use of the supplement led to a marked decrease in headache frequency after experiencing migraines postpartum (Read Review).

Additionally, many users emphasized that iron supplementation was beneficial, particularly in cases where individuals were diagnosed with low iron levels. For example, one reviewer mentioned that their migraines improved alongside other health benefits after increasing their ferritin levels from slightly below 20 to 56 (Read Review). Overall, while specific dosing may not have been uniformly mentioned, the consensus seems to indicate that regular supplementation, particularly in the context of diagnosed iron deficiency, may be key to alleviating migraine symptoms.

8.8
Improved migraine symptoms
I struggle with severe iron deficiency, and this specific supplement helped me immensely. I started taking it when my iron level was around 70, and within two weeks it improved to 85! It felt miraculous, as I also felt my migraines ease somewhat—low iron levels might be a trigger for them. I highly recommend it and noticed no side effects.
9.5
Decreased headache frequency
After giving birth, I consistently suffered from migraine headaches. However, after taking this supplement steadily for over a month, my headache frequency has decreased significantly.
10
Eliminated migraines completely
Before starting these capsules, I had my ferritin level checked, which was at 11.2 ng/ml. Two months later, after taking one pill a day with 500mg of Vitamin C, I've noticed a significant improvement and my migraines have completely disappeared!
9.5
Decreased menstrual headaches
The quality and ingredients are excellent. I used to have intense headaches during menstruation, yet after trying iron supplements on a pharmacist's recommendation, the symptoms decreased immediately. I suspect my long-standing migraines were linked to iron deficiency. It's a must-have.
8.8
Less frequent migraines
The result is confirmed by analyses. This medication was recommended by my doctor who looked at both hemoglobin and ferritin, which was slightly below 20 for me. Three months of taking it with vitamin C raised my ferritin to 56. I noticed subjectively that my migraines have become less intriguing, and I also experienced improvements such as reduced tingling in my extremities and decreased hair loss. This medication was essential, and I've stocked up on it now.
8
Iron's impact on migraine relief
We examined the link between iron deficiency anemia and migraines to understand how iron levels affect migraine symptoms. Our research confirmed that individuals suffering from migraines, especially women, tend to have lower iron levels. This suggests a significant relationship where low iron may worsen migraine frequency and intensity.

Through our literature review, we discovered that iron supplementation has been beneficial for some migraine sufferers, particularly those with diagnosed iron deficiency anemia. By increasing iron levels, we noted improvements in migraine symptoms, making it a potential treatment strategy worth considering.

However, we also highlighted that while iron supplementation shows promise, it’s essential to approach treatment carefully. Further research is necessary to determine the long-term effects and to establish guidelines on its use, minimizing any risks of iron overload. Overall, we advocate for incorporating nutritional evaluations into migraine management strategies to enhance patient outcomes effectively.
We investigated how dietary iron intake and serum ferritin levels relate to severe headaches and migraines in American adults. This research drew on data from 7,880 adults, aged 20 and above, collected between 1999 and 2004 as part of the National Health and Nutrition Examination Surveys (NHANES).

Our findings were particularly interesting for women aged 20 to 50 years, who generally consumed less iron than recommended. We observed that higher dietary iron intake in this group was linked to a lower occurrence of severe headaches or migraines. On the other hand, for women over 50, we discovered that greater serum ferritin levels—essentially a marker of iron storage—seemed to be associated with fewer migraine incidents.

However, for men, we found no significant connection between dietary iron and migraines. This suggests that the link between iron and migraines might be influenced by different biological factors, particularly hormonal changes in women related to menstrual cycles.

Overall, our results highlight the importance of proper dietary iron intake for women, especially those in their childbearing years, as it may help prevent severe headaches. For older women, maintaining higher ferritin levels could provide some protection against migraines as well.
7
Iron deficiency anemia and migraines
We set out to understand the relationship between iron deficiency anemia and migraine attacks. This study involved a case-control design, where we compared migraine sufferers with healthy individuals who did not have migraines or anemia, except for iron deficiency. Each group had at least 100 participants, allowing us to examine how iron levels influenced migraine incidents.

Our findings revealed that in females, there were significant differences in hemoglobin and serum ferritin levels when comparing those with migraines and those without. This suggests that low iron levels might be linked to more frequent or severe migraine attacks in women. However, we found no significant differences in iron levels or anemia among male participants.

Interestingly, while the study suggested an association between iron deficiency anemia and migraine severity in females, we also observed that treatment efforts or prophylactic measures, such as iron supplements, may hold potential benefits for women experiencing migraines associated with anemia. Still, we recognized that more research is needed to draw firm conclusions and clarify any remaining questions about this connection.
We explored the potential link between iron levels in the brain and migraine attacks through a series of MRI scans. By looking at measures of brain iron content and white matter structure in a 26-year-old male migraine patient over 21 days, including both migraine-free days and days of attacks, we aimed to understand how iron might fluctuate during these episodes.

Our findings revealed interesting patterns: we observed that iron content in the brain changes during the migraine cycle. Specifically, there was an increase in white matter iron levels during migraine attacks. Alongside this, we noticed a decrease in the anisotropic properties of the brain tissue, suggesting that there might be additional changes happening in the brain's vascular system during these painful episodes.

While these results provide insights into how iron may play a role in migraine, it is important to note that the study does not confirm any direct benefits of iron treatment on migraines. Our work highlights the complexities of migraine pathology, but the direct impact of iron management remains unclear at this stage.

References

  1. Birkl C, Filippi V, Steiger R, Frank F, Magnesius S, et al. Dynamic fluctuations in brain iron content during migraine attacks: insights from relaxometry and diffusion tensor imaging. Front Neurol. 2024;15:1422313. doi:10.3389/fneur.2024.1422313
  2. Al-Qassab ZM, Ahmed O, Kannan V, Ullah N, Geddada S, et al. Iron Deficiency Anemia and Migraine: A Literature Review of the Prevalence, Pathophysiology, and Therapeutic Potential. Cureus. 2024;16:e69652. doi:10.7759/cureus.69652
  3. Meng SH, Zhou HB, Li X, Wang MX, Kang LX, et al. Association Between Dietary Iron Intake and Serum Ferritin and Severe Headache or Migraine. Front Nutr. 2021;8:685564. doi:10.3389/fnut.2021.685564
  4. Tayyebi A, Poursadeghfard M, Nazeri M, Pousadeghfard T. Is There Any Correlation between Migraine Attacks and Iron Deficiency Anemia? A Case-Control Study. Int J Hematol Oncol Stem Cell Res. 2019;13:164.
image