Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 4 Reviews
8.5
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Iron (as iron bisglycinate chelate†)
25 mg
139%
Top Medical Research Studies
8
We explored the potential of iron chelation in combating yeast infections caused by the common fungus Candida, which can lead to serious systemic diseases. Our research involved screening over 3,000 unique compounds from a specialized chemical library to identify those that effectively inhibited the growth of a clinical isolate of Candida.
Through this extensive screening, we discovered 17 promising compounds, with three—CMLD013360, CMLD012661, and CMLD012693—showing particularly strong antifungal effects. These compounds belong to two different chemical families and are believed to combat fungal growth by binding to essential metal nutrients like iron.
Interestingly, when we supplemented the growth media with iron, we observed a recovery in the fungus’s growth. This confirmed that the antifungal activity of our compounds was indeed due to their capacity to chelate iron. Importantly, our findings also revealed that these compounds were effective against a variety of other pathogenic fungi, thus underscoring their potential as new treatments in an era where antifungal resistance is becoming increasingly common.
Overall, this study highlights the critical role that iron chelation can play in tackling yeast infections and opens up exciting avenues for the development of novel antifungal therapies.
Through this extensive screening, we discovered 17 promising compounds, with three—CMLD013360, CMLD012661, and CMLD012693—showing particularly strong antifungal effects. These compounds belong to two different chemical families and are believed to combat fungal growth by binding to essential metal nutrients like iron.
Interestingly, when we supplemented the growth media with iron, we observed a recovery in the fungus’s growth. This confirmed that the antifungal activity of our compounds was indeed due to their capacity to chelate iron. Importantly, our findings also revealed that these compounds were effective against a variety of other pathogenic fungi, thus underscoring their potential as new treatments in an era where antifungal resistance is becoming increasingly common.
Overall, this study highlights the critical role that iron chelation can play in tackling yeast infections and opens up exciting avenues for the development of novel antifungal therapies.
Read More
9
MION effectively targets yeast infections
We investigated how magnetic iron oxide nanoparticles (MION) could impact Candida albicans, a common yeast infection that often becomes resistant to standard treatments like fluconazole. Our approach included testing MION alone and in combination with visible light to see how effective this treatment could be.
During our research, we found that MION at a certain concentration (500 μg/mL) was quite effective against various strains of C. albicans. When we combined MION with visible light, the results were even more impressive, showing strong fungicidal effects after 24 and 48 hours. This combination also led to the highest levels of reactive oxygen species (ROS)—chemicals that can damage and kill fungal cells.
We also examined the effects on specific genes known to be important in the virulence of C. albicans, specifically HWP1 and ALS1. Our results indicated that these genes were significantly downregulated, particularly when MION was used alongside visible light. This suggests that MION could serve as a great option for treating infections caused by resistant strains of Candida.
Overall, our findings highlight the potential of using MION, especially when combined with visible light, to effectively target Candida albicans and its associated virulence genes.
During our research, we found that MION at a certain concentration (500 μg/mL) was quite effective against various strains of C. albicans. When we combined MION with visible light, the results were even more impressive, showing strong fungicidal effects after 24 and 48 hours. This combination also led to the highest levels of reactive oxygen species (ROS)—chemicals that can damage and kill fungal cells.
We also examined the effects on specific genes known to be important in the virulence of C. albicans, specifically HWP1 and ALS1. Our results indicated that these genes were significantly downregulated, particularly when MION was used alongside visible light. This suggests that MION could serve as a great option for treating infections caused by resistant strains of Candida.
Overall, our findings highlight the potential of using MION, especially when combined with visible light, to effectively target Candida albicans and its associated virulence genes.
Read More
Most Useful Reviews
9
Increased energy levels
36 people found this helpful
HEMOGLOBIN IS GOING UP IMMEDIATELY! Excellent drug. Iron in the chelated form of bisglycinate. A trusted company, a highly bioavailable form of iron that is easily digestible. It does not cause constipation and works gently, with no side effects. It helped me restore my ferritin levels and normalise my haemoglobin levels. The effects make me feel more energetic and less lethargic. My mother also took it and was satisfied. Iron is vital for transporting oxygen to tissues, metabolic processes, and maintaining immune function. Iron deficiency results in extreme fatigue and other issues. If my review was useful to you, please put YES 👍
Read More
7.5
Effective ferritin boost
1 people found this helpful
Great product from a reputable brand! I purchased this iron to increase my ferritin levels, which were previously at 18. In a month, I will retest my iron and ferritin levels. It's essential to avoid iron during acute infections and wait for remission before resuming. This drug did not upset my digestion; everything worked perfectly. After taking one capsule, my ferritin levels rose to 43 ng/ml, which I consider a good result, even though I occasionally missed doses. I believe I can reach my optimal ferritin concentration of 100-150 by the end of month two.
Read More
7.5
Positive treatment outcomes
1 people found this helpful
The drug genuinely works! The fact that it comes from a leading dietary supplement manufacturer gives me confidence in treating my iron deficiency anaemia, which was diagnosed last summer. My haemoglobin levels were dangerously low. After addressing my habits, I decided not to visit the clinic due to fears of infections there. I switched to this SOLGAR product and took two tablets with meals for three weeks. The results are promising — dark circles under my eyes diminished, and I feel much more cheerful. Apathy and fatigue have gradually lifted, and I’ve regained a sense of vitality in my mornings.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
MION effectively targets yeast infections
We investigated how magnetic iron oxide nanoparticles (MION) could impact Candida albicans, a common yeast infection that often becomes resistant to standard treatments like fluconazole. Our approach included testing MION alone and in combination with visible light to see how effective this treatment could be.
During our research, we found that MION at a certain concentration (500 μg/mL) was quite effective against various strains of C. albicans. When we combined MION with visible light, the results were even more impressive, showing strong fungicidal effects after 24 and 48 hours. This combination also led to the highest levels of reactive oxygen species (ROS)—chemicals that can damage and kill fungal cells.
We also examined the effects on specific genes known to be important in the virulence of C. albicans, specifically HWP1 and ALS1. Our results indicated that these genes were significantly downregulated, particularly when MION was used alongside visible light. This suggests that MION could serve as a great option for treating infections caused by resistant strains of Candida.
Overall, our findings highlight the potential of using MION, especially when combined with visible light, to effectively target Candida albicans and its associated virulence genes.
During our research, we found that MION at a certain concentration (500 μg/mL) was quite effective against various strains of C. albicans. When we combined MION with visible light, the results were even more impressive, showing strong fungicidal effects after 24 and 48 hours. This combination also led to the highest levels of reactive oxygen species (ROS)—chemicals that can damage and kill fungal cells.
We also examined the effects on specific genes known to be important in the virulence of C. albicans, specifically HWP1 and ALS1. Our results indicated that these genes were significantly downregulated, particularly when MION was used alongside visible light. This suggests that MION could serve as a great option for treating infections caused by resistant strains of Candida.
Overall, our findings highlight the potential of using MION, especially when combined with visible light, to effectively target Candida albicans and its associated virulence genes.
Read More
8
We explored the potential of iron chelation in combating yeast infections caused by the common fungus Candida, which can lead to serious systemic diseases. Our research involved screening over 3,000 unique compounds from a specialized chemical library to identify those that effectively inhibited the growth of a clinical isolate of Candida.
Through this extensive screening, we discovered 17 promising compounds, with three—CMLD013360, CMLD012661, and CMLD012693—showing particularly strong antifungal effects. These compounds belong to two different chemical families and are believed to combat fungal growth by binding to essential metal nutrients like iron.
Interestingly, when we supplemented the growth media with iron, we observed a recovery in the fungus’s growth. This confirmed that the antifungal activity of our compounds was indeed due to their capacity to chelate iron. Importantly, our findings also revealed that these compounds were effective against a variety of other pathogenic fungi, thus underscoring their potential as new treatments in an era where antifungal resistance is becoming increasingly common.
Overall, this study highlights the critical role that iron chelation can play in tackling yeast infections and opens up exciting avenues for the development of novel antifungal therapies.
Through this extensive screening, we discovered 17 promising compounds, with three—CMLD013360, CMLD012661, and CMLD012693—showing particularly strong antifungal effects. These compounds belong to two different chemical families and are believed to combat fungal growth by binding to essential metal nutrients like iron.
Interestingly, when we supplemented the growth media with iron, we observed a recovery in the fungus’s growth. This confirmed that the antifungal activity of our compounds was indeed due to their capacity to chelate iron. Importantly, our findings also revealed that these compounds were effective against a variety of other pathogenic fungi, thus underscoring their potential as new treatments in an era where antifungal resistance is becoming increasingly common.
Overall, this study highlights the critical role that iron chelation can play in tackling yeast infections and opens up exciting avenues for the development of novel antifungal therapies.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9
Increased energy levels
36 people found this helpful
HEMOGLOBIN IS GOING UP IMMEDIATELY! Excellent drug. Iron in the chelated form of bisglycinate. A trusted company, a highly bioavailable form of iron that is easily digestible. It does not cause constipation and works gently, with no side effects. It helped me restore my ferritin levels and normalise my haemoglobin levels. The effects make me feel more energetic and less lethargic. My mother also took it and was satisfied. Iron is vital for transporting oxygen to tissues, metabolic processes, and maintaining immune function. Iron deficiency results in extreme fatigue and other issues. If my review was useful to you, please put YES 👍
Read More
7.5
Effective ferritin boost
1 people found this helpful
Great product from a reputable brand! I purchased this iron to increase my ferritin levels, which were previously at 18. In a month, I will retest my iron and ferritin levels. It's essential to avoid iron during acute infections and wait for remission before resuming. This drug did not upset my digestion; everything worked perfectly. After taking one capsule, my ferritin levels rose to 43 ng/ml, which I consider a good result, even though I occasionally missed doses. I believe I can reach my optimal ferritin concentration of 100-150 by the end of month two.
Read More
7.5
Positive treatment outcomes
1 people found this helpful
The drug genuinely works! The fact that it comes from a leading dietary supplement manufacturer gives me confidence in treating my iron deficiency anaemia, which was diagnosed last summer. My haemoglobin levels were dangerously low. After addressing my habits, I decided not to visit the clinic due to fears of infections there. I switched to this SOLGAR product and took two tablets with meals for three weeks. The results are promising — dark circles under my eyes diminished, and I feel much more cheerful. Apathy and fatigue have gradually lifted, and I’ve regained a sense of vitality in my mornings.
Read More
7.5
Visible health improvement
The best iron for our body! I have been using iron from this manufacturer for a while, and I noticed results in just two weeks. My health has notably improved, and I recommend this product. I haven't noticed any side effects, and the dosage is easy — one capsule daily with a meal. The ingredients are free from gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavours, sweeteners, preservatives, and colours. The size is small, and the packaging is sealed.
Read More
Frequently Asked Questions
9
Increased energy levels
36 people found this helpful
HEMOGLOBIN IS GOING UP IMMEDIATELY! Excellent drug. Iron in the chelated form of bisglycinate. A trusted company, a highly bioavailable form of iron that is easily digestible. It does not cause constipation and works gently, with no side effects. It helped me restore my ferritin levels and normalise my haemoglobin levels. The effects make me feel more energetic and less lethargic. My mother also took it and was satisfied. Iron is vital for transporting oxygen to tissues, metabolic processes, and maintaining immune function. Iron deficiency results in extreme fatigue and other issues. If my review was useful to you, please put YES 👍
7.5
Effective ferritin boost
1 people found this helpful
Great product from a reputable brand! I purchased this iron to increase my ferritin levels, which were previously at 18. In a month, I will retest my iron and ferritin levels. It's essential to avoid iron during acute infections and wait for remission before resuming. This drug did not upset my digestion; everything worked perfectly. After taking one capsule, my ferritin levels rose to 43 ng/ml, which I consider a good result, even though I occasionally missed doses. I believe I can reach my optimal ferritin concentration of 100-150 by the end of month two.
7.5
Positive treatment outcomes
1 people found this helpful
The drug genuinely works! The fact that it comes from a leading dietary supplement manufacturer gives me confidence in treating my iron deficiency anaemia, which was diagnosed last summer. My haemoglobin levels were dangerously low. After addressing my habits, I decided not to visit the clinic due to fears of infections there. I switched to this SOLGAR product and took two tablets with meals for three weeks. The results are promising — dark circles under my eyes diminished, and I feel much more cheerful. Apathy and fatigue have gradually lifted, and I’ve regained a sense of vitality in my mornings.
7.5
Visible health improvement
The best iron for our body! I have been using iron from this manufacturer for a while, and I noticed results in just two weeks. My health has notably improved, and I recommend this product. I haven't noticed any side effects, and the dosage is easy — one capsule daily with a meal. The ingredients are free from gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavours, sweeteners, preservatives, and colours. The size is small, and the packaging is sealed.
8
We explored the potential of iron chelation in combating yeast infections caused by the common fungus Candida, which can lead to serious systemic diseases. Our research involved screening over 3,000 unique compounds from a specialized chemical library to identify those that effectively inhibited the growth of a clinical isolate of Candida.
Through this extensive screening, we discovered 17 promising compounds, with three—CMLD013360, CMLD012661, and CMLD012693—showing particularly strong antifungal effects. These compounds belong to two different chemical families and are believed to combat fungal growth by binding to essential metal nutrients like iron.
Interestingly, when we supplemented the growth media with iron, we observed a recovery in the fungus’s growth. This confirmed that the antifungal activity of our compounds was indeed due to their capacity to chelate iron. Importantly, our findings also revealed that these compounds were effective against a variety of other pathogenic fungi, thus underscoring their potential as new treatments in an era where antifungal resistance is becoming increasingly common.
Overall, this study highlights the critical role that iron chelation can play in tackling yeast infections and opens up exciting avenues for the development of novel antifungal therapies.
Through this extensive screening, we discovered 17 promising compounds, with three—CMLD013360, CMLD012661, and CMLD012693—showing particularly strong antifungal effects. These compounds belong to two different chemical families and are believed to combat fungal growth by binding to essential metal nutrients like iron.
Interestingly, when we supplemented the growth media with iron, we observed a recovery in the fungus’s growth. This confirmed that the antifungal activity of our compounds was indeed due to their capacity to chelate iron. Importantly, our findings also revealed that these compounds were effective against a variety of other pathogenic fungi, thus underscoring their potential as new treatments in an era where antifungal resistance is becoming increasingly common.
Overall, this study highlights the critical role that iron chelation can play in tackling yeast infections and opens up exciting avenues for the development of novel antifungal therapies.
9
MION effectively targets yeast infections
We investigated how magnetic iron oxide nanoparticles (MION) could impact Candida albicans, a common yeast infection that often becomes resistant to standard treatments like fluconazole. Our approach included testing MION alone and in combination with visible light to see how effective this treatment could be.
During our research, we found that MION at a certain concentration (500 μg/mL) was quite effective against various strains of C. albicans. When we combined MION with visible light, the results were even more impressive, showing strong fungicidal effects after 24 and 48 hours. This combination also led to the highest levels of reactive oxygen species (ROS)—chemicals that can damage and kill fungal cells.
We also examined the effects on specific genes known to be important in the virulence of C. albicans, specifically HWP1 and ALS1. Our results indicated that these genes were significantly downregulated, particularly when MION was used alongside visible light. This suggests that MION could serve as a great option for treating infections caused by resistant strains of Candida.
Overall, our findings highlight the potential of using MION, especially when combined with visible light, to effectively target Candida albicans and its associated virulence genes.
During our research, we found that MION at a certain concentration (500 μg/mL) was quite effective against various strains of C. albicans. When we combined MION with visible light, the results were even more impressive, showing strong fungicidal effects after 24 and 48 hours. This combination also led to the highest levels of reactive oxygen species (ROS)—chemicals that can damage and kill fungal cells.
We also examined the effects on specific genes known to be important in the virulence of C. albicans, specifically HWP1 and ALS1. Our results indicated that these genes were significantly downregulated, particularly when MION was used alongside visible light. This suggests that MION could serve as a great option for treating infections caused by resistant strains of Candida.
Overall, our findings highlight the potential of using MION, especially when combined with visible light, to effectively target Candida albicans and its associated virulence genes.
References
- Fallah S, Duncan D, Reichl KD, Smith MJ, Wang W, et al. A chemical screen identifies structurally diverse metal chelators with activity against the fungal pathogen . Microbiol Spectr. 2024;12:e0409523. doi:10.1128/spectrum.04095-23
- Khodavandi P, Hosseini A, Khodavandi A, Alizadeh F, Azizi A, et al. Hyphae-specific genes: Possible molecular targets for magnetic iron oxide nanoparticles alone and combined with visible light in Candida albicans. Photodiagnosis Photodyn Ther. 2023;44:103822. doi:10.1016/j.pdpdt.2023.103822
