Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 31 Reviews
8.2
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
L-Lysine (as L-lysine HCl) (Free Form)
500 mg
**
Top Medical Research Studies
9
We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Read More
8
Our exploration centered on how a specific compound derived from l-lysine, known as G2 dendrimer, influences Cutibacterium acnes, the bacteria linked to acne vulgaris. We found that this compound can alter the behavior of acneic strains of C. acnes by changing their membrane fluidity and reducing biofilm formation. Interestingly, it does not have the same effects on non-acneic strains, indicating a targeted action.
In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.
The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.
The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
Read More
Most Useful Reviews
7.5
Gradual acne improvement
136 people found this helpful
Yup, it helps! Not an immediate solution, but I noticed significant improvement in the frequency and size of my acne. After starting L-lysine, my hyperpigmentation is also improving.
Read More
10
Cystic acne cure
71 people found this helpful
This is the only thing that cured my awful cystic acne in just three weeks! I've previously tried accutane, curology, and rodan and fields with no results. After starting one pill a day, I stopped breaking out within the first two weeks. Now, after two months, the only blemish I had was a small pimple during PMS last month. I highly recommend it if you feel you have incurable acne; thankfully, I experienced no side effects, although I've heard about some experiencing stomach cramps.
Read More
9.5
Effective remedy
41 people found this helpful
I researched this pill for my sudden adult onset acne, which resurfaced after seven years without any issues due to birth control. I had small bumps on my forehead and breakouts on my nose and chin, reminiscent of my teenage years. I tried various natural face washes and masks with little improvement. This pill resolved 95% of my acne within a month. I know it’s effective because I didn’t alter my routine apart from taking this daily. No negatives at all; if you're facing acne issues, you should give it a go.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Read More
8
Our exploration centered on how a specific compound derived from l-lysine, known as G2 dendrimer, influences Cutibacterium acnes, the bacteria linked to acne vulgaris. We found that this compound can alter the behavior of acneic strains of C. acnes by changing their membrane fluidity and reducing biofilm formation. Interestingly, it does not have the same effects on non-acneic strains, indicating a targeted action.
In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.
The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.
The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
Read More
User Reviews
USERS' SCORE
Good
Based on 31 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Gradual acne improvement
136 people found this helpful
Yup, it helps! Not an immediate solution, but I noticed significant improvement in the frequency and size of my acne. After starting L-lysine, my hyperpigmentation is also improving.
Read More
10
Cystic acne cure
71 people found this helpful
This is the only thing that cured my awful cystic acne in just three weeks! I've previously tried accutane, curology, and rodan and fields with no results. After starting one pill a day, I stopped breaking out within the first two weeks. Now, after two months, the only blemish I had was a small pimple during PMS last month. I highly recommend it if you feel you have incurable acne; thankfully, I experienced no side effects, although I've heard about some experiencing stomach cramps.
Read More
9.5
Effective remedy
41 people found this helpful
I researched this pill for my sudden adult onset acne, which resurfaced after seven years without any issues due to birth control. I had small bumps on my forehead and breakouts on my nose and chin, reminiscent of my teenage years. I tried various natural face washes and masks with little improvement. This pill resolved 95% of my acne within a month. I know it’s effective because I didn’t alter my routine apart from taking this daily. No negatives at all; if you're facing acne issues, you should give it a go.
Read More
9.5
Effective support
29 people found this helpful
This was recommended by Organic Olivia for treating acne. After having a severe outbreak of what I believe was cystic acne, I began using it for two months. Initially, I took several herbal remedies with no change in my acne. However, once I added L-lysine and burdock root capsules, I saw improvement within days. My skin is now 95% better, and I hope for further progress. I did stop taking L-lysine for a while due to running out, but I noticed breakouts on my forehead, chin, and nose returning. I realise now it was due to my discontinuation of the supplement. I've ordered more and am taking it regularly again, seeing improvement once more.
Read More
10
Remarkable results
16 people found this helpful
THIS WORKS WONDERS. At 37, I have dealt with various forms of acne my entire life. I wish I had discovered this product twenty years ago. Taking just one pill a day has resulted in my skin being clearer than it has ever been. I have tried virtually every product known for acne, and nothing has been as effective as this. I've spent a fortune on dermatological treatments, including painful Fraxel treatments, yet nothing compared to the effects of this product.
Read More
Frequently Asked Questions
9
Reduced acne
This is a genuine find for those experiencing hair loss. It enhances the condition of my nails and skin. My teenage daughter and I have noticed significantly less acne, and our skin has noticeably improved. My hair, which was previously falling out, has become thicker!
9
We explored the effects of G2 lysine dendrimer on acne and how it can help restore balance to our skin microbiome. Acne is a persistent skin condition that brings about discomfort and concerns for many. Traditional treatments can often lose their effectiveness over time or lead to unwanted side effects. So, our goal was to see if this new approach could offer a gentler solution.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
Our focus was on how G2 dendrimer specifically targets the troublesome bacteria associated with acne while preserving the healthy bacteria we rely on for healthy skin. Through our studies, we found that G2 dendrimer notably reduced inflammatory markers linked to acne, such as IL-8. What’s more, it didn’t harm the beneficial bacteria on the skin, which is essential for maintaining overall skin health.
We also conducted comparisons with standard over-the-counter treatments. The G2 dendrimer showed promising results in both limiting acne outbreaks and supporting the survival of good bacteria. Through metagenomic analysis, we confirmed that using G2 in a cosmetic product can effectively help rebalance the acne-prone microbiota without disrupting the friendly bacteria.
Overall, these findings highlight the potential of G2 lysine dendrimer as a non-aggressive option for acne prevention while respecting our skin's natural microbiome.
8
Our exploration centered on how a specific compound derived from l-lysine, known as G2 dendrimer, influences Cutibacterium acnes, the bacteria linked to acne vulgaris. We found that this compound can alter the behavior of acneic strains of C. acnes by changing their membrane fluidity and reducing biofilm formation. Interestingly, it does not have the same effects on non-acneic strains, indicating a targeted action.
In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.
The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
In our investigations using skin samples, we observed that G2 dendrimer significantly lowers indicators of inflammation, such as IL1α and TLR-2, and promotes better skin cell turnover after colonization by acneic strains. To solidify our findings, we performed a 28-day treatment with a G2 cream and measured changes in bacteria diversity through metagenomic analysis.
The results showed not only an increase in the diversity of C. acnes strains but also a shift regarding the balance between different phylotypes associated with acne. Overall, our findings highlight the potential for using gentle, soft compounds like the G2 dendrimer as a new strategy to manage and possibly prevent acne outbreaks by modifying the bacterial population on the skin.
References
- Leignadier J, Drago M, Lesouhaitier O, Barreau M, Dashi A, et al. Lysine-Dendrimer, a New Non-Aggressive Solution to Rebalance the Microbiota of Acne-Prone Skin. Pharmaceutics. 2023;15. doi:10.3390/pharmaceutics15082083
- Attia-Vigneau J, Barreau M, Le Toquin E, Feuilloley MGJ, Loing E, et al. Polylysine dendrigraft is able to differentially impact Cutibacterium acnes strains preventing acneic skin. Exp Dermatol. 2022;31:1056. doi:10.1111/exd.14554
