Last update
3/16/2026
Research Authors

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
L-Lysine (as L-lysine HCl) (Free Form)
500 mg
**
📅 Last updated:

Top Medical Research Studies

8
Anxiety reduction observed with lysine
We investigated how L-lysine, an essential amino acid, influences anxiety and body weight. The study involved administering two doses of L-lys to rats over 20 days.

We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.

However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.
Read More

Most Useful Reviews

9
Helps with anxiety
2 people found this helpful
Perfectly! I take it on an empty stomach before meals. Lysine supplementation can assist those who are depressed and relieve anxiety and stress symptoms.
Read More
7.5
Amino acid aids anxiety
I recommend this hazelnut-derived amino acid. It strengthens immunity, enhances skin and hair, stimulates muscle growth, and reduces anxiety. I noticed results after a few weeks, and there have been no side effects on my stomach.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Anxiety reduction observed with lysine
We investigated how L-lysine, an essential amino acid, influences anxiety and body weight. The study involved administering two doses of L-lys to rats over 20 days.

We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.

However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Helps with anxiety
2 people found this helpful
Perfectly! I take it on an empty stomach before meals. Lysine supplementation can assist those who are depressed and relieve anxiety and stress symptoms.
Read More
7.5
Amino acid aids anxiety
I recommend this hazelnut-derived amino acid. It strengthens immunity, enhances skin and hair, stimulates muscle growth, and reduces anxiety. I noticed results after a few weeks, and there have been no side effects on my stomach.
Read More

Frequently Asked Questions

7.5
Amino acid aids anxiety
I recommend this hazelnut-derived amino acid. It strengthens immunity, enhances skin and hair, stimulates muscle growth, and reduces anxiety. I noticed results after a few weeks, and there have been no side effects on my stomach.
9
Helps with anxiety
2 people found this helpful
Perfectly! I take it on an empty stomach before meals. Lysine supplementation can assist those who are depressed and relieve anxiety and stress symptoms.
8
Anxiety reduction observed with lysine
We investigated how L-lysine, an essential amino acid, influences anxiety and body weight. The study involved administering two doses of L-lys to rats over 20 days.

We found that while L-lys didn't affect food intake, it did lead to weight reduction and showed signs of anxiolytic effects on the first day. Notably, repeated doses increased serotonin levels in key brain areas, which may explain its calming effects.

However, the study's outcomes indicate that L-lys may not dramatically alter anxiety compared to other treatments.

References

  1. Jalal K, Khan F, Nawaz S, Afroz R, Khan K, et al. Anxiolytic, anti-nociceptive and body weight reducing effects of L-lysine in rats: Relationship with brain serotonin an In-Vivo and In-Silico study. Biomed Pharmacother. 2022;152:113235. 10.1016/j.biopha.2022.113235
Data last updated:
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