We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
Read More
9
Magnesium nanoparticles enhance clotting time
Effect of Biofunctional Green Synthesized MgO-Nanoparticles on Oxidative-Stress-Induced Tissue Damage and Thrombosis.
We investigated the effects of magnesium oxide nanoparticles, created using fruit extract, on blood clotting and oxidative stress. Our experiments showed that these nanoparticles significantly extended clotting time, indicating an anticoagulant effect. They also effectively reduced damage to red blood cells and various tissues in laboratory tests, helping to restore their function. Importantly, we found these nanoparticles non-toxic, suggesting they could be a promising treatment option for oxidative stress-related conditions without adverse side effects. However, further research is needed to fully understand their potential in clinical applications.
Read More
8
Magnesium scaffolds lower clotting risks
A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds.
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
Read More
Most Useful Reviews
9
Heart health improved
238 people found this helpful
Magnesium citrate enhances heart and blood vessel health, regulating blood pressure and heartbeat rhythm. It also aids in stress management and improves sleep quality, all packaged in a convenient glass jar that assures quality.
Read More
9
Muscle cramps ceased
I am very pleased with the quality of this dietary supplement. My sleep has returned to normal, and muscle cramps have stopped. This isn’t my first purchase of this product; the benefits became clear after my tests showed that magnesium levels in my blood had risen to the necessary range. I highly recommend magnesium citrate.
Read More
7.5
Helps menstrual issues
Magnesium citrate helps normalise blood pressure and has calming effects, which can relieve menstrual disorders and sleep issues. It plays a crucial role in muscle and blood vessel relaxation, significantly enhancing overall well-being.
We investigated the effects of magnesium oxide nanoparticles, created using fruit extract, on blood clotting and oxidative stress. Our experiments showed that these nanoparticles significantly extended clotting time, indicating an anticoagulant effect. They also effectively reduced damage to red blood cells and various tissues in laboratory tests, helping to restore their function. Importantly, we found these nanoparticles non-toxic, suggesting they could be a promising treatment option for oxidative stress-related conditions without adverse side effects. However, further research is needed to fully understand their potential in clinical applications.
Read More
8
Magnesium intake reduces RVO risk
Sufficient Magnesium Intake Reduces Retinal Vein Occlusion Risk: National Health and Nutrition Examination Survey Analysis.
We explored whether magnesium intake could influence the risk of retinal vein occlusion (RVO), a leading cause of vision loss. Our analysis involved over 16,000 participants from a national health survey.
We discovered that sufficient magnesium intake was linked to a significant 64% reduced risk of RVO.
This finding was especially relevant for adults under 60, those with hypertension, and individuals without glaucoma. Further studies are needed to confirm magnesium's preventive benefits for RVO.
Read More
8
Effective clay-based hemostatic sponge
An Antibacterial, Antioxidant Adherent Sponge Constructed for Control of Arterial Bleeding Via Gallic Acid-Mediated Robust Assembly of Fibrous Clay in Collagen.
We examined a new sponge made from clay and collagen to control severe bleeding. Integrating palygorskite clay with collagen using gallic acid created a sponge that resists particle shedding and provides strong adhesion.
In our tests, this sponge demonstrated impressive results, reducing blood loss to 632 mg and achieving hemostasis in just 151 seconds, outperforming traditional gauze and even a well-known product called QuikClot.
With added antibacterial and antioxidant properties, this sponge could significantly enhance emergency bleeding management.
Read More
8
Magnesium scaffolds lower clotting risks
A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds.
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
Read More
8
Bioresorbable stents' advancements noted
Coronary bioresorbable metallic stents: Advancements and future perspectives.
We explored the evolution of bioresorbable metallic stents as alternatives to traditional stents which can lead to complications like thrombosis and inflammation.
While bioresorbable polymeric stents face challenges, materials like zinc and magnesium show promise.
Specifically, magnesium-based stents have demonstrated successful absorption within a year and low rates of complications.
Continuing research will be essential to refine these innovations for better clinical outcomes.
Magnesium citrate enhances heart and blood vessel health, regulating blood pressure and heartbeat rhythm. It also aids in stress management and improves sleep quality, all packaged in a convenient glass jar that assures quality.
Read More
9
Muscle cramps ceased
I am very pleased with the quality of this dietary supplement. My sleep has returned to normal, and muscle cramps have stopped. This isn’t my first purchase of this product; the benefits became clear after my tests showed that magnesium levels in my blood had risen to the necessary range. I highly recommend magnesium citrate.
Read More
7.5
Helps menstrual issues
Magnesium citrate helps normalise blood pressure and has calming effects, which can relieve menstrual disorders and sleep issues. It plays a crucial role in muscle and blood vessel relaxation, significantly enhancing overall well-being.
Read More
9
Improves sleep quality
3 people found this helpful
Fantastic product! Since August 2020, I take two tablets before dinner, leading to better sleep, normal blood pressure, and regular bowel movements. At 59 years old, I find these supplements essential for my health!
Read More
7.5
Improved sleep quality
Although magnesium citrate is not the cheapest option, it is reasonably priced compared to other magnesium products in Russia. Taking two tablets daily provides a two-month supply. It is well absorbed but may have a mild laxative effect. After two months, I experienced no issues; my sleep improved, blood pressure stabilised, and muscle cramps ceased.
A blood clot is a mass of blood that changes from a liquid to a gel, effectively forming a plug that can stop bleeding. This natural process, known as coagulation, is critical for preventing excessive blood loss when you sustain an injury. Blood clots can occur in various areas of the body, typically at the site of a wound, but they can also form within blood vessels without an obvious injury, which may lead to serious health complications.
While blood clots are essential for healing, they can pose significant health risks if they form inappropriately. For example, a deep vein thrombosis (DVT) occurs when a clot forms in a deep vein, usually in the legs, and can travel to the lungs, causing a life-threatening condition called a pulmonary embolism. Risk factors for blood clots include prolonged immobility, certain medical conditions, and the use of specific medications, among others. It’s important to recognize the symptoms of abnormal clotting, such as swelling, pain, and redness in the affected area, and seek medical attention if they occur.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Based on user reviews, the timeline for seeing results from magnesium citrate supplements, particularly in relation to blood clot issues and overall cardiovascular health, varies among individuals. Users report noticing improvements in their symptoms within a few weeks to a couple of months. For example, one user highlighted significant benefits, including improved blood pressure and the cessation of muscle cramps, after a consistent two-month regimen Read Review.
Additionally, another reviewer mentioned feeling better sleep and normalized blood pressure after a similar duration, indicating that while individual experiences may differ, around two months seems to be a common timeframe for observing attributed benefits Read Review. However, some users did not specify an exact timeframe, emphasizing the importance of consistent use for longer-term benefits related to heart health and blood clot prevention Read Review. Overall, patience and consistent supplementation appear key for achieving intended results.
Based on recent scientific research, magnesium does appear to have a supportive role in managing blood clot risks. A study found that magnesium scaffolds, such as the Magmaris and DREAMS 3G, demonstrate significantly lower thrombogenicity compared to traditional stents, implying that these magnesium-based stents could enhance patient safety and reduce complications related to blood clots during cardiovascular interventions [3][4]. Additionally, another study indicated that a deficiency in magnesium is linked to increased platelet activity and a higher risk of thrombotic events, suggesting adequate magnesium levels could be critical for vascular health and potentially reduce thrombosis risks [8].
Moreover, magnesium levels have been associated with coagulopathy, particularly in septic patients, where low magnesium has been correlated with a higher likelihood of activated coagulation [14]. These findings support the notion that maintaining appropriate magnesium levels may be beneficial for those at risk of blood clotting disorders and further research could uncover more about the therapeutic potential of magnesium in this context.
Users report a range of positive improvements in their symptoms after taking magnesium citrate, emphasizing its role in supporting cardiovascular and overall health. Many reviewers, such as one who noted normalizing blood pressure and experiencing muscle relaxation, highlight its calming effects which can also relieve menstrual disorders and sleep issues Read Review. Another user experienced enhanced sleep quality and ceased muscle cramps after regular use, attributing their wellbeing to the supplement's effectiveness Read Review.
Additionally, a reviewer shared that consistent intake of magnesium citrate led to significant health benefits, including stable blood pressure and regular bowel movements—a notable improvement for many users in maintaining their overall wellness as they age Read Review. Others emphasize the importance of patience and continued use, as they noticed effects such as improved general calmness, further underscoring its suitability for individuals experiencing anxiety or sleep disruptions Read Review. Overall, while experiences can vary, many users report substantial benefits with consistent supplementation.
Based on user reviews, many individuals report positive experiences when using magnesium citrate in conjunction with other supplements to manage blood clot and cardiovascular health. Users highlight its effectiveness in promoting heart health and assisting in blood pressure regulation, indicating that it can serve as a supportive dietary addition for those concerned about blood clots Read Review. One reviewer specifically noted that magnesium citrate not only enhances cardiovascular function but also plays a role in preventing blood clot formation, suggesting that these benefits could be further optimized when combined with other heart-healthy supplements Read Review.
Moreover, users emphasize the importance of maintaining an adequate magnesium level for overall health, with reports indicating that proper supplementation leads to normal blood pressure and a reduction in muscle cramps Read Review. These effects could potentially be beneficial alongside other dietary adjustments or supplements tailored for cardiovascular support, underscoring the value of a holistic approach to health management in relation to blood clots Read Review. Overall, while individual responses may vary, the consensus suggests that magnesium citrate is a valuable component in the wider strategy for maintaining vascular health.
Users report various positive outcomes related to magnesium intake for treating blood clots and enhancing cardiovascular health. Many users highlighted that taking magnesium citrate not only aids in normalising blood pressure but also promotes heart health and reduces the likelihood of blood clot formation. One user specifically mentioned that taking magnesium helped with maintaining 120/80 blood pressure levels without the need for medication, showcasing its potential for blood pressure regulation and overall cardiovascular benefits Read Review.
Regarding the right dosage, it appears that users commonly take around two tablets daily, with some reporting a significant improvement in health markers after consistent use. One user noted that this dosage led to enhancements in sleep quality, muscle relaxation, and overall well-being Read Review, while another user advocated for the calming effects it offers Read Review. Although specific dosage recommendations were not consistently outlined, the most frequent user feedback suggests that a daily intake of two tablets can be effective for managing blood pressure and contributing to overall health.
7.5
Improved sleep quality
Although magnesium citrate is not the cheapest option, it is reasonably priced compared to other magnesium products in Russia. Taking two tablets daily provides a two-month supply. It is well absorbed but may have a mild laxative effect. After two months, I experienced no issues; my sleep improved, blood pressure stabilised, and muscle cramps ceased.
9
Improves sleep quality
3 people found this helpful
Fantastic product! Since August 2020, I take two tablets before dinner, leading to better sleep, normal blood pressure, and regular bowel movements. At 59 years old, I find these supplements essential for my health!
7.5
Stress management
8 people found this helpful
This magnesium works well, particularly beneficial for women. It promotes heart health, helps prevent blood clot formation, and balances cholesterol. A morning pill keeps my nerves in check, providing superior calmness compared to other solutions.
7.5
Helps menstrual issues
Magnesium citrate helps normalise blood pressure and has calming effects, which can relieve menstrual disorders and sleep issues. It plays a crucial role in muscle and blood vessel relaxation, significantly enhancing overall well-being.
9
Muscle cramps ceased
I am very pleased with the quality of this dietary supplement. My sleep has returned to normal, and muscle cramps have stopped. This isn’t my first purchase of this product; the benefits became clear after my tests showed that magnesium levels in my blood had risen to the necessary range. I highly recommend magnesium citrate.
7.5
Calms and relaxes
Magnesium citrate helps to normalise blood pressure and has an antispasmodic effect on muscles and blood vessels. It positively impacts the cardiovascular system, providing a calming effect, making it useful for sleep disorders and anxiety. Excellent 👍
7.5
Family health improvement
1 people found this helpful
Magnesium is a vital necessity! It has helped everyone in my family; my husband's mother has stopped taking blood pressure medication, and my husband and I have maintained 120/80 blood pressure for two years. It also resolves constipation effectively.
8
Magnesium scaffolds lower clotting risks
A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds.
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
8
Bioresorbable stents' advancements noted
Coronary bioresorbable metallic stents: Advancements and future perspectives.
We explored the evolution of bioresorbable metallic stents as alternatives to traditional stents which can lead to complications like thrombosis and inflammation.
While bioresorbable polymeric stents face challenges, materials like zinc and magnesium show promise.
Specifically, magnesium-based stents have demonstrated successful absorption within a year and low rates of complications.
Continuing research will be essential to refine these innovations for better clinical outcomes.
8
MAGT1 deficiency increases thrombosis risk
MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice.
We studied how a lack of magnesium transporter 1 (MAGT1) impacts blood clot formation and the risk of stroke. Using various laboratory and animal models, we observed that MAGT1 deficiency leads to enhanced platelet activity and quicker clotting. This deficiency resulted in faster artery blockage and severe brain damage during strokes. Interestingly, restoring magnesium levels or blocking certain channels helped normalize platelet behavior. Overall, we found that MAGT1's function is crucial for vascular health, indicating its deficiency could elevate risks for thrombosis and ischemic stroke.
7
Magnesium affects sepsis coagulopathy
Association between hypomagnesemia and coagulopathy in sepsis: a retrospective observational study.
We looked into how magnesium levels impact blood clotting during sepsis. In our study of ICU patients, we found that those with low magnesium (hypomagnesemia) showed a higher likelihood of having activated coagulation and suppressed fibrinolysis.
Notably, hypomagnesemia was linked to coagulopathy, specifically disseminated intravascular coagulation (DIC). This suggests that boosting magnesium levels could be a promising way to address blood clotting issues in septic patients.
References
Kim J, Kim M, Lee CS, Choi EY. Sufficient Magnesium Intake Reduces Retinal Vein Occlusion Risk: National Health and Nutrition Examination Survey Analysis. Nutrients. 2025;17. doi:10.3390/nu17071285
Guo X, Zeng X, He Y, Zhang X, Shi W, et al. An Antibacterial, Antioxidant Adherent Sponge Constructed for Control of Arterial Bleeding Via Gallic Acid-Mediated Robust Assembly of Fibrous Clay in Collagen. ACS Appl Mater Interfaces. 2025;17:16489. doi:10.1021/acsami.4c19209
Müller M, Ludwig L, Englert H, Riedl KA, Müller MC, et al. A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds. Sci Rep. 2024;14:26691. doi:10.1038/s41598-024-77266-0
Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. doi:10.1016/j.jjcc.2024.08.003
Włodarczak A, Rola P, Włodarczak S, Szudrowicz M, Giniewicz K, et al. Two-Year Outcomes for Patients with Non-ST-Elevation Acute Coronary Syndrome Treated with Magmaris and Absorb Bioresorbable Scaffolds in Large-Vessel Lesions. J Pers Med. 2024;14. doi:10.3390/jpm14050540
Galli S, Troiano S, Palloshi A, Rapetto C, Pisano F, et al. Comparison of acute versus stable coronary syndrome in patients treated with the Magmaris scaffold: Two-year results from the Magmaris Multicenter Italian Registry. Cardiovasc Revasc Med. 2023;57:53. doi:10.1016/j.carrev.2023.06.022
Włodarczak A, Rola P, Barycki M, Furtan Ł, Łanocha M, et al. Mid-term safety and efficacy of magnesium bioresorbable vascular scaffolds - magmaris in diabetic population. 2-Years outcome in acute coronary syndrome cohort. Diab Vasc Dis Res. 2023;20:14791641231188705. doi:10.1177/14791641231188705
Gotru SK, Mammadova-Bach E, Sogkas G, Schuhmann MK, Schmitt K, et al. MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice. Arterioscler Thromb Vasc Biol. 2023;43:1494. doi:10.1161/ATVBAHA.122.318115
Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. A new resorbable magnesium scaffold for de novo coronary lesions (DREAMS 3): one-year results of the BIOMAG-I first-in-human study. EuroIntervention. 2023;19:e414. doi:10.4244/EIJ-D-23-00326
Wlodarczak A, Montorsi P, Torzewski J, Bennett J, Starmer G, et al. One- and two-year clinical outcomes of treatment with resorbable magnesium scaffolds for coronary artery disease: the prospective, international, multicentre BIOSOLVE-IV registry. EuroIntervention. 2023;19:232. doi:10.4244/EIJ-D-22-01069
Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. Safety and performance of the third-generation drug-eluting resorbable coronary magnesium scaffold system in the treatment of subjects with de novo coronary artery lesions: 6-month results of the prospective, multicenter BIOMAG-I first-in-human study. EClinicalMedicine. 2023;59:101940. doi:10.1016/j.eclinm.2023.101940
Pompei G, Campo G, Ruggiero R, Maffeo D, Sgura F, et al. Long-term outcomes of patients treated with sirolimus-eluting resorbable magnesium scaffolds: Insights from the SHERPA-MAGIC study. Int J Cardiol. 2023;383:1. doi:10.1016/j.ijcard.2023.04.029
Fedele G, Castiglioni S, Maier JAM, Locatelli L. The Effects of Sirolimus and Magnesium on Primary Human Coronary Endothelial Cells: An In Vitro Study. Int J Mol Sci. 2023;24. doi:10.3390/ijms24032930
Tonai K, Katayama S, Koyama K, Sata N, Tomioka Y, et al. Association between hypomagnesemia and coagulopathy in sepsis: a retrospective observational study. BMC Anesthesiol. 2022;22:359. doi:10.1186/s12871-022-01903-2
Seguchi M, Aytekin A, Lenz T, Nicol P, Alvarez-Covarrubias HA, et al. Challenges of the newer generation of resorbable magnesium scaffolds: Lessons from failure mechanisms of the past generation. J Cardiol. 2023;81:179. doi:10.1016/j.jjcc.2022.09.003
Venkatappa MM, Udagani C, Hanumegowda SM, Pramod SN, Venkataramaiah S, et al. Effect of Biofunctional Green Synthesized MgO-Nanoparticles on Oxidative-Stress-Induced Tissue Damage and Thrombosis. Molecules. 2022;27. doi:10.3390/molecules27165162