Medical Researches
Moderately Effective
Based on 5 Researches
Magnesium improves pregnancy hypertensionEffects of magnesium sulfate combined with labetalol on vascular endothelial function and pregnancy outcomes in pregnant women with preeclampsia.
Combination treatment effectively evaluated
We conducted a retrospective study to investigate how magnesium sulfate paired with labetalol affects vascular health and pregnancy outcomes in women with preeclampsia—a serious condition that can occur during pregnancy characterized by high blood pressure.
Our analysis focused on clinical data from 262 women treated for preeclampsia. The patients were divided into two groups: one group received magnesium sulfate alone, while the other group was treated with both magnesium sulfate and labetalol. By measuring key indicators such as nitric oxide and endothelin-1 levels, along with blood pressure readings, we aimed to determine the effectiveness of these treatments.
The results showed that the combination of magnesium sulfate and labetalol notably improved vascular function and pregnancy outcomes for these women. Not only did this treatment help in better controlling high blood pressure during pregnancy, but it also reduced the chances of adverse outcomes for both mothers and babies. Importantly, the study found this combined treatment to be as safe as using magnesium sulfate alone.
This reinforces the idea that magnesium can play a significant role in treating hypertension during pregnancy, especially when paired with other medications like labetalol.
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Magnesium's effects on PAH treatmentMonocrotaline-induced pulmonary arterial hypertension: the benefic effects of magnesium sulfate, Rosuvastatin and Sildenafil.
Combination treatment limits isolation
We examined an experimental model of pulmonary arterial hypertension (PAH) induced by monocrotaline in rats. Our research focused on the combined effects of Magnesium sulfate along with Rosuvastatin and Sildenafil, which were administered two weeks after the initial MCT injection.
Using measures like the Fulton Index and various cardiac dimensions, we observed improvements in right ventricular function and markers of oxidative stress. Notably, Magnesium sulfate appeared to work well with Rosuvastatin, which is known for its anti-inflammatory properties, enhancing the overall treatment effectiveness on pulmonary hypertension.
However, since Magnesium was administered in combination with these other treatments, we could not determine its isolated benefits on hypertension specifically. The study did highlight the importance of multi-pronged approaches in tackling such complex conditions, suggesting that further research might clarify Magnesium's unique contributions to managing hypertension.
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Magnesium effectively lowers blood pressureMagnesium and Potassium Supplementation for Systolic Blood Pressure Reduction in the General Normotensive Population: A Systematic Review and Subgroup Meta-Analysis for Optimal Dosage and Treatment Length.
Focuses on magnesium's effects
We explored how magnesium supplementation can affect systolic blood pressure (SBP) in the general population. Through careful analysis of placebo-controlled, randomized clinical trials, we focused on understanding the optimal dosages and treatment durations necessary to achieve significant reductions in SBP. Past findings revealed that magnesium could reduce SBP by an average of 2.79 mm Hg, and our goal was to dive deeper into these results.
Our meta-analysis showed promising outcomes. Specifically, we noticed that magnesium taken at lower doses, particularly ≤360 mg per day, led to a notable decrease in SBP of about 3.03 mm Hg, especially when the treatment duration exceeded three months. This suggests that for those looking to manage their blood pressure, longer-term use of magnesium at these dosages may be beneficial.
While we found encouraging evidence pointing to the effectiveness of magnesium in lowering SBP, we acknowledge the importance of further studies. These future investigations should focus on varied dosages and longer follow-up periods to strengthen our understanding and provide tailored recommendations for individuals seeking to utilize magnesium in their hypertension management strategies.
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Magnesium's impact on hypertensionAssociation of magnesium deficiency, tobacco smoke exposure and hypertension in children and adolescents: evidence from the NHANES 2007-2018.
Explores magnesium and tobacco smoke
We explored the relationship between dietary magnesium intake, tobacco smoke exposure, and hypertension among children and adolescents. This research utilized data from the National Health and Nutrition Examination Surveys (NHANES) spanning from 2007 to 2018, which allowed us to analyze a broad range of participants.
Our findings revealed a notable link between low magnesium intake and higher chances of developing hypertension, especially for those exposed to tobacco smoke. In fact, children and adolescents with a deficiency in magnesium and who lived around tobacco smoke exhibited significantly increased odds of hypertension.
Based on this evidence, we suggest that addressing magnesium deficiency and implementing stricter measures on tobacco smoking could play an important role in preventing and managing high blood pressure in young people.
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We conducted a randomized clinical trial to explore the effects of magnesium from deep ocean sources on adults dealing with hypertension, diabetes, or high cholesterol. Patients participated by consuming either magnesium-enriched water or a placebo over a four-week period.
Throughout the trial, we focused on key health indicators, including body mass index (BMI) and levels of insulin and triglycerides, among others. Our findings indicated that, despite some participants consuming less magnesium than the recommended daily allowance, those who drank magnesium-enriched water showed meaningful improvements in various metabolic markers.
Notably, we found that this water not only supported better metabolic outcomes but also positively influenced gut microbiome diversity. The magnesium-enriched water helped maintain a balanced abundance of beneficial gut bacteria, which is crucial for overall health. This indicates that boosting our magnesium intake, through sources like deep ocean water, might play a valuable role in controlling hypertension and possibly preventing related conditions without any significant adverse effects.
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User Reviews
Great for regularity and hypertension. During my research into high blood pressure, I discovered magnesium deficiency is prevalent, as soil depletion has resulted in its absence in fertilizers. This deficiency can contribute to hypertension. The citrate form of Magnesium also aids regularity. After taking it for about a year (one daily when I eat well, 2 or 3 when I don't), it consistently lowers my blood pressure by 10-15 points, and regularity is no longer an issue. I additionally take Garden of Life Raw Probiotics for women over 50. The Solgar brand offers excellent quality at a reasonable price.
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Great product for hypertension. I read The Magnesium Miracle by Carolyn Dean and Reversing Hypertension by Julian Whitaker, seeking ways to normalise my blood pressure and discontinue medication taken for a year. Both books recommend Magnesium Citrate. Taking just two tablets (the recommended RDA amount), I noticed a difference from day one. I experienced sustained energy throughout the day, as if my blood cells had been oxygenated. My bathroom visits became more regular, and after battling insomnia for nearly three years, I finally sleep soundly through the night. I highly recommend any product from Solgar, especially for those with magnesium imbalance. If you're considering exceeding the daily allowance, consult your doctor first.
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