Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 5 Reviews
8.2
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
5
Vitamin A (100% as natural beta-carotene from D. salina algae)
7,500 mcg
833%
Carotenoid Blend (from D. salina)(providing natural carotenoids: alpha-carotene, cryptoxanthin, zeaxanthin, lutein)
816 mcg
**
Top Medical Research Studies
9.5
We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Read More
9
We investigated the impact of vitamin A, specifically isotretinoin, on acne through its use in treating frontal fibrosing alopecia (FFA). Our exploration included a comprehensive review of the available research, focusing on its effectiveness in alleviating symptoms related to acne, especially in the context of hair loss and facial papules.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
Read More
9
We explored how viaminate, a vitamin A acid treatment commonly used in acne therapy, impacts the skin. To investigate this, acne was induced in rat ears using a combination of acne bacteria and sebum. After 30 days of treatment, we saw a remarkable improvement in the thickening and keratin overproduction associated with acne.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
Read More
Most Useful Reviews
7.5
Helped with acne
4 people found this helpful
I have a skin issue with acne and I'm delighted with the results from this complex. One of the vitamins really helped. However, there are contraindications for smokers and those on oral contraceptives, so dosage adjustments may be necessary.
Read More
9
Good for skin
I’m very pleased with Solgar's natural oceanic beta-carotene. It’s derived from D.salina algae and is beneficial for acne-prone skin. It supports immunity, enhances skin resilience, and helps retain moisture. My skin feels better, and the transformation occurs when experiencing vitamin A deficiency.
Read More
9
Noticed skin improvement
Vitamin A, in the form of beta-carotene, is vital for combating acne. It has antioxidant properties and I've noticed a significant improvement in my skin since taking one capsule after lunch daily. I've also cut out sweets and milk, which has helped further.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
- All Researches
9.5
Impact of Isotretinoin on Liver Function
We conducted a retrospective study to understand how vitamin A, particularly in the form of oral isotretinoin, impacts acne treatment. This powerful medication is often prescribed for severe cases of acne that don’t respond to other treatments.
Our research reviewed medical records of 50 patients aged between 13 and 40 years who received isotretinoin at Ibri Polyclinic from 2012 to 2022. Over the treatment period, we observed notable changes in liver function and lipid profiles among the patients.
Specifically, after treatment, there were increases in liver enzymes indicating changes in liver function, as well as fluctuations in cholesterol and triglyceride levels. These findings suggest potential risks associated with isotretinoin, highlighting the need for careful monitoring.
While isotretinoin does show effectiveness in treating severe acne, there’s an evident impact on liver health and lipid metabolism that we must consider when prescribing this medication. More research is necessary to fully unravel these effects and guide future treatments.
Our research reviewed medical records of 50 patients aged between 13 and 40 years who received isotretinoin at Ibri Polyclinic from 2012 to 2022. Over the treatment period, we observed notable changes in liver function and lipid profiles among the patients.
Specifically, after treatment, there were increases in liver enzymes indicating changes in liver function, as well as fluctuations in cholesterol and triglyceride levels. These findings suggest potential risks associated with isotretinoin, highlighting the need for careful monitoring.
While isotretinoin does show effectiveness in treating severe acne, there’s an evident impact on liver health and lipid metabolism that we must consider when prescribing this medication. More research is necessary to fully unravel these effects and guide future treatments.
Read More
9.5
We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Read More
9
We explored the effectiveness of retinoic acid, commonly known as vitamin A, for acne treatment using a unique delivery method that combines proliposomes and nanofibers. The goal was to assess how these specially formulated nanofibers, loaded with retinoic acid, could inhibit microbial biofilm formation, a common contributor to acne.
In our study, we created various formulations of blank and retinoic acid-loaded proliposomal nanofibers. By using different ratios of polyvinylpyrrolidone, phosphatidylcholine, and cholesterol, we aimed to optimize the delivery system. Our findings showed that these formulations were able to form liposomes rapidly after hydration and had appropriate characteristics such as vesicle size and stability.
Notably, the ATRA (all-trans retinoic acid) loaded nanofibers demonstrated greater bioadhesion than a commercial cream, suggesting they may adhere better to the skin. The results indicated these nanofibers offered superior antibacterial and anti-biofilm effects compared to retinoic acid alone. This suggests that this innovative delivery method could enhance the effectiveness of vitamin A in acne treatment.
Overall, the study highlights the promising potential of combining nanofibers and liposomes to improve acne treatment outcomes, showing that vitamin A can be more effective when delivered using this advanced method.
In our study, we created various formulations of blank and retinoic acid-loaded proliposomal nanofibers. By using different ratios of polyvinylpyrrolidone, phosphatidylcholine, and cholesterol, we aimed to optimize the delivery system. Our findings showed that these formulations were able to form liposomes rapidly after hydration and had appropriate characteristics such as vesicle size and stability.
Notably, the ATRA (all-trans retinoic acid) loaded nanofibers demonstrated greater bioadhesion than a commercial cream, suggesting they may adhere better to the skin. The results indicated these nanofibers offered superior antibacterial and anti-biofilm effects compared to retinoic acid alone. This suggests that this innovative delivery method could enhance the effectiveness of vitamin A in acne treatment.
Overall, the study highlights the promising potential of combining nanofibers and liposomes to improve acne treatment outcomes, showing that vitamin A can be more effective when delivered using this advanced method.
Read More
9
We investigated the impact of vitamin A, specifically isotretinoin, on acne through its use in treating frontal fibrosing alopecia (FFA). Our exploration included a comprehensive review of the available research, focusing on its effectiveness in alleviating symptoms related to acne, especially in the context of hair loss and facial papules.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
The analysis covered 15 relevant studies involving 232 FFA patients. Remarkably, nearly 90% of these individuals reported a significant reduction in symptoms after daily doses of 10-40 mg of isotretinoin. This indicates that vitamin A, in the form of isotretinoin, effectively addresses not only the physical manifestations of acne but also helps improve overall skin health.
Our findings suggest that isotretinoin holds promise as a treatment option, particularly for those struggling with the dual challenges of FFA and acne. While further research is warranted, the current evidence strongly supports its role in mitigating acne symptoms.
Read More
9
We explored how viaminate, a vitamin A acid treatment commonly used in acne therapy, impacts the skin. To investigate this, acne was induced in rat ears using a combination of acne bacteria and sebum. After 30 days of treatment, we saw a remarkable improvement in the thickening and keratin overproduction associated with acne.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
Our analysis indicated that viaminate effectively modifies certain pathways related to skin cell behavior. Specifically, we observed a significant reduction in the expression of the S100A8 and S100A9 proteins, which are known to play a role in inflammation and skin proliferation. Furthermore, viaminate suppressed the activity of the MAPK pathway, which is vital for managing skin cell growth and differentiation.
Importantly, when we administered S100A8 and S100A9 proteins alongside viaminate, we found that this reversed its beneficial effects, highlighting the importance of these proteins in viaminate’s mechanism of action. Overall, our findings suggest that viaminate could serve as an effective option for treating acne by regulating cellular processes that contribute to its development.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Helped with acne
4 people found this helpful
I have a skin issue with acne and I'm delighted with the results from this complex. One of the vitamins really helped. However, there are contraindications for smokers and those on oral contraceptives, so dosage adjustments may be necessary.
Read More
9
Good for skin
I’m very pleased with Solgar's natural oceanic beta-carotene. It’s derived from D.salina algae and is beneficial for acne-prone skin. It supports immunity, enhances skin resilience, and helps retain moisture. My skin feels better, and the transformation occurs when experiencing vitamin A deficiency.
Read More
9
Noticed skin improvement
Vitamin A, in the form of beta-carotene, is vital for combating acne. It has antioxidant properties and I've noticed a significant improvement in my skin since taking one capsule after lunch daily. I've also cut out sweets and milk, which has helped further.
Read More
6
Minor improvements noted
1 people found this helpful
My sister (35) had poor absorption of vitamin A, which led to rough skin. After taking it for a month, there were small improvements, though not drastic. I also struggle with acne and pigmentation, but my skin managed well during winter sun exposure.
Read More
7.5
Effective against acne
These are quality vitamins! Beta-carotene, or provitamin A, not only speeds up tanning but also supports the immune system and benefits acne-prone skin. It's effective against the first signs of ageing, and I've noticed quick results after starting this supplement!
Read More
Frequently Asked Questions
6
Minor improvements noted
1 people found this helpful
My sister (35) had poor absorption of vitamin A, which led to rough skin. After taking it for a month, there were small improvements, though not drastic. I also struggle with acne and pigmentation, but my skin managed well during winter sun exposure.
7.5
Effective against acne
These are quality vitamins! Beta-carotene, or provitamin A, not only speeds up tanning but also supports the immune system and benefits acne-prone skin. It's effective against the first signs of ageing, and I've noticed quick results after starting this supplement!
9
Noticed skin improvement
Vitamin A, in the form of beta-carotene, is vital for combating acne. It has antioxidant properties and I've noticed a significant improvement in my skin since taking one capsule after lunch daily. I've also cut out sweets and milk, which has helped further.
7.5
Helped with acne
4 people found this helpful
I have a skin issue with acne and I'm delighted with the results from this complex. One of the vitamins really helped. However, there are contraindications for smokers and those on oral contraceptives, so dosage adjustments may be necessary.
9
Good for skin
I’m very pleased with Solgar's natural oceanic beta-carotene. It’s derived from D.salina algae and is beneficial for acne-prone skin. It supports immunity, enhances skin resilience, and helps retain moisture. My skin feels better, and the transformation occurs when experiencing vitamin A deficiency.
9.5
We explored how vitamin A can influence acne treatment, focusing on the effectiveness of its derivatives. According to the findings, oral isotretinoin, a form of vitamin A, showed remarkable efficacy. Patients experienced a significant reduction in lesions—up to 90%—with complete remission in one-quarter of those involved in the study.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
Moreover, more than half of the participants reported substantial improvement after treatment. This strong performance suggests that vitamin A plays a key role in managing acne symptoms effectively.
Overall, the evidence we examined indicates that incorporating vitamin A, particularly through isotretinoin, can lead to significant improvements for individuals struggling with acne.
9.5
Impact of Isotretinoin on Liver Function
We conducted a retrospective study to understand how vitamin A, particularly in the form of oral isotretinoin, impacts acne treatment. This powerful medication is often prescribed for severe cases of acne that don’t respond to other treatments.
Our research reviewed medical records of 50 patients aged between 13 and 40 years who received isotretinoin at Ibri Polyclinic from 2012 to 2022. Over the treatment period, we observed notable changes in liver function and lipid profiles among the patients.
Specifically, after treatment, there were increases in liver enzymes indicating changes in liver function, as well as fluctuations in cholesterol and triglyceride levels. These findings suggest potential risks associated with isotretinoin, highlighting the need for careful monitoring.
While isotretinoin does show effectiveness in treating severe acne, there’s an evident impact on liver health and lipid metabolism that we must consider when prescribing this medication. More research is necessary to fully unravel these effects and guide future treatments.
Our research reviewed medical records of 50 patients aged between 13 and 40 years who received isotretinoin at Ibri Polyclinic from 2012 to 2022. Over the treatment period, we observed notable changes in liver function and lipid profiles among the patients.
Specifically, after treatment, there were increases in liver enzymes indicating changes in liver function, as well as fluctuations in cholesterol and triglyceride levels. These findings suggest potential risks associated with isotretinoin, highlighting the need for careful monitoring.
While isotretinoin does show effectiveness in treating severe acne, there’s an evident impact on liver health and lipid metabolism that we must consider when prescribing this medication. More research is necessary to fully unravel these effects and guide future treatments.
7
We investigated how vitamin A, in the form of retinoic acid (RA), impacts acne treatment when combined with other agents. The study utilized innovative liposomes that encapsulate both proteinase K and RA alongside soyaethyl morpholinium ethosulfate (SME), aiming for a dual action against acne by targeting both bacterial infection and inflammation.
Our findings showed that these multifunctional liposomes not only demonstrated significant antimicrobial effects, reducing bacterial colonies by 62%, but also effectively restrained the hyperproliferation of keratinocytes, the skin cells that can contribute to acne development. Unlike free forms of RA, which could enhance skin irritation, the liposomal version proved to have better skin tolerability.
Additionally, we noted that RA-loaded nanovesicles outperformed traditional free RA in improving skin barrier function. Overall, this study provides promising evidence that using RA within these specialized liposomes could potentially revolutionize acne treatments by effectively managing both the causes and symptoms of this condition.
Our findings showed that these multifunctional liposomes not only demonstrated significant antimicrobial effects, reducing bacterial colonies by 62%, but also effectively restrained the hyperproliferation of keratinocytes, the skin cells that can contribute to acne development. Unlike free forms of RA, which could enhance skin irritation, the liposomal version proved to have better skin tolerability.
Additionally, we noted that RA-loaded nanovesicles outperformed traditional free RA in improving skin barrier function. Overall, this study provides promising evidence that using RA within these specialized liposomes could potentially revolutionize acne treatments by effectively managing both the causes and symptoms of this condition.
7
In our exploration of the effects of isotretinoin, a high-dose vitamin A treatment for acne vulgaris, we focused on how it might influence anger levels in patients. We analyzed a group of 100 individuals, half receiving isotretinoin for their acne and half acting as a control group without any medication. This structure allowed us to assess the emotional responses more effectively.
Our findings revealed an interesting connection: patients taking isotretinoin showed increased levels of anger compared to those who weren’t. We particularly noted a correlation between certain temperament traits—like being cyclothymic or hyperthymic—and different anger responses. For instance, individuals with a cyclothymic temperament exhibited anxiety-related behaviors, while those with a hyperthymic temperament had a greater tendency towards certain anger-related thoughts.
Although we delved into how acne treatment can be linked with emotional well-being, it’s important to clarify that while isotretinoin addresses acne effectively, it can also create emotional fluctuations for some individuals. Our study adds a unique perspective by highlighting the psychological dimensions associated with acne treatment, which haven’t been deeply explored in previous research.
Our findings revealed an interesting connection: patients taking isotretinoin showed increased levels of anger compared to those who weren’t. We particularly noted a correlation between certain temperament traits—like being cyclothymic or hyperthymic—and different anger responses. For instance, individuals with a cyclothymic temperament exhibited anxiety-related behaviors, while those with a hyperthymic temperament had a greater tendency towards certain anger-related thoughts.
Although we delved into how acne treatment can be linked with emotional well-being, it’s important to clarify that while isotretinoin addresses acne effectively, it can also create emotional fluctuations for some individuals. Our study adds a unique perspective by highlighting the psychological dimensions associated with acne treatment, which haven’t been deeply explored in previous research.
4
We explored the role of vitamin A, specifically its active form, all-trans retinoic acid (ATRA), in the treatment of acne. Retinoids like ATRA are known for their ability to influence skin cell growth and differentiation, which is important when it comes to managing acne.
Our findings suggest that ATRA interacts with specific receptors in the body, helping to regulate acne-related processes. By binding to retinoic acid receptors, ATRA may assist in controlling the factors that lead to acne breakouts.
It's worth noting that while retinoids show potential, effective treatments depend on various factors, including individual responses. We observed that newer modifications to retinoid compounds may enhance their efficacy in treating acne.
Overall, while vitamin A does have a role in acne treatment, the effectiveness can vary, and more research is necessary to determine the best approaches for different individuals.
Our findings suggest that ATRA interacts with specific receptors in the body, helping to regulate acne-related processes. By binding to retinoic acid receptors, ATRA may assist in controlling the factors that lead to acne breakouts.
It's worth noting that while retinoids show potential, effective treatments depend on various factors, including individual responses. We observed that newer modifications to retinoid compounds may enhance their efficacy in treating acne.
Overall, while vitamin A does have a role in acne treatment, the effectiveness can vary, and more research is necessary to determine the best approaches for different individuals.
8
We conducted a study looking into how vitamin A, particularly in the form of isotretinoin, affects severe acne vulgaris (AV). This inflammatory skin condition can lead to both physical and emotional distress, and we aimed to understand whether vitamin A could help alleviate these symptoms.
A total of 100 patients with severe acne participated in our research, taking 0.75 mg/kg of isotretinoin daily for a span of four months. Throughout this time, we closely monitored serum vitamin D levels at three key points: before, during, and after the treatment.
Our findings indicated that although severe acne may negatively affect vitamin D synthesis, the treatment with isotretinoin leads to an increase in vitamin D serum levels. This suggests a potential benefit of vitamin A treatment in improving vitamin D status in those suffering from severe AV. However, further studies are needed to clarify the relationship between the two.
A total of 100 patients with severe acne participated in our research, taking 0.75 mg/kg of isotretinoin daily for a span of four months. Throughout this time, we closely monitored serum vitamin D levels at three key points: before, during, and after the treatment.
Our findings indicated that although severe acne may negatively affect vitamin D synthesis, the treatment with isotretinoin leads to an increase in vitamin D serum levels. This suggests a potential benefit of vitamin A treatment in improving vitamin D status in those suffering from severe AV. However, further studies are needed to clarify the relationship between the two.
References
- Abuallut II, Dibaji MQ, Assiri A, Mawkili W, Najmi AY, et al. Oral Isotretinoin-Associated Ocular Effects and Risk Factors: A Cross-Sectional Study. Clin Ophthalmol. 2024;18:4041. doi:10.2147/OPTH.S491757
- Yaqoubi WSAA, Touby SSJA, Hossain MA. Laboratory investigations of liver function and lipid profiles tests before and after oral isotretinoin treatment among Acne valgaris clients at Ibri Polyclinic: A retrospective study. Toxicol Rep. 2024;13:101799. doi:10.1016/j.toxrep.2024.101799
- Tort S, Öztürk ZC, Kaynak-Onurdağ F, Mutlu-Ağardan NB. Preparation and evaluation the effects of retinoic acid loaded proliposomal nanofibers on microbial biofilm inhibition. Pharm Dev Technol. 2024;29:955. doi:10.1080/10837450.2024.2411034
- Kulaklı S, Elmas Telli AC, Sarı İF, Oğuz ID, Kulaklı F. Increased femoral cartilage thickness in acne patients using isotretinoin: could it be a sign of early osteoarthritis?. Arch Dermatol Res. 2024;316:512. doi:10.1007/s00403-024-03264-x
- Powała K, Żołek T, Brown G, Kutner A. Molecular Interactions of Selective Agonists and Antagonists with the Retinoic Acid Receptor γ. Int J Mol Sci. 2024;25. doi:10.3390/ijms25126568
- Hussein RS, Dayel SB, Abahussein O. Prospective study of the effects of isotretinoin and vitamin D levels on severe acne vulgaris. Turk J Med Sci. 2023;53:1732. doi:10.55730/1300-0144.5742
- Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4
- Shahpar A, Nezhad NZ, Sahaf AS, Ahramiyanpour N. A review of isotretinoin in the treatment of frontal fibrosing alopecia. J Cosmet Dermatol. 2024;23:1956. doi:10.1111/jocd.16245
- Demir EY, Köse ÖK. Effects of oral isotretinoin treatment for acne vulgaris patients on anger responses and the relationship with temperament. Rev Assoc Med Bras (1992). 2023;70:e20230592. doi:10.1590/1806-9282.20230592
- Cao J, Xu M, Zhu L, Xiao S. Viaminate Inhibits Acnes-induced Abnormal Proliferation and Keratinization of HaCat Cells by Regulating the S100A8/S100A9- MAPK Cascade. Curr Drug Targets. 2023;24:1055. doi:10.2174/0113894501243867230928115205
- Tsai MJ, Lin CY, Trousil J, Sung CT, Lee MH, et al. Proteinase K/Retinoic Acid-Loaded Cationic Liposomes as Multifunctional Anti-Acne Therapy to Disorganize Biofilm and Regulate Keratinocyte Proliferation. Int J Nanomedicine. 2023;18:3879. doi:10.2147/IJN.S416966
- Gurel A, Gurel G, Fırat F, Ozgul E, Turkoglu IND, et al. Effect of systemic isotretinoin therapy on semen parameters. Ann Med. 2023;55:2207038. doi:10.1080/07853890.2023.2207038
- Cook MK, Perche PO, Feldman SR. The use of oral vitamin A in acne management: a review. Dermatol Online J. 2022;28. doi:10.5070/D328559239
- Cao J, Xu M, Zhu L, Xiao S. Viaminate ameliorates Propionibacterium acnes-induced acne via inhibition of the TLR2/NF-κB and MAPK pathways in rats. Naunyn Schmiedebergs Arch Pharmacol. 2023;396:1487. doi:10.1007/s00210-022-02379-0
- Kontzias C, Zaino M, Feldman SR. Tretinoin 0.1% and Benzoyl Peroxide 3% Cream for the Treatment of Facial Acne Vulgaris. Ann Pharmacother. 2023;57:1088. doi:10.1177/10600280221147338
- Kosmoski G, Miller D, Coret C, Atillasoy E. A Topical Combination Regimen of Benzoyl Peroxide and Retinol Moisturizer for Mild to Moderate Acne. J Drugs Dermatol. 2022;21:1340. doi:10.36849/JDD.6845
