This study looked at how a combination of stable ozonides and vitamin E acetate, called Ozoile, helps relieve symptoms of genitourinary syndrome in menopausal women.
After 20 days of treatment, we observed a significant reduction in symptoms such as pain and dryness, with pain incidence decreasing from 16.7% to 11.8% and dryness dropping from 85.5% to 53.8%.
Although Ozoile demonstrated effectiveness in addressing these symptoms, more research is necessary to understand how it compares to other treatments for this condition.
Read More
SEDDS enhances tocotrienol benefitsTherapeutic potential of annatto tocotrienol with self-emulsifying drug delivery system in a rat model of postmenopausal bone loss.
High relevance for osteoporosis research
We aimed to explore the effects of annatto tocotrienol, especially when paired with a self-emulsifying drug delivery system (SEDDS), on bone loss in a rat model of postmenopause.
After conducting a comprehensive study, we found that the SEDDS formulation significantly boosted the levels of delta-tocotrienol and was effective in promoting bone strength and health.
While both SEDDS-formulated and unformulated tocotrienol improved bone structure, the SEDDS offered superior results in certain areas, such as trabecular microstructure.
Overall, this suggests a promising path for human trials to further investigate tocotrienol's impact on postmenopausal bone health.
Read More
Pollen extract shows symptom reliefProspective observational study to evaluate the efficacy and safety of the pollen extract Sérélys in the management of women with menopausal symptoms.
Highly relevant to menopause research
We aimed to understand the effectiveness of the pollen extract Sérélys, combined with vitamin E, in reducing menopausal symptoms in women. In a multicenter study, 104 menopausal women took the extract for three months. Their symptoms were assessed, revealing significant reductions: hot flashes decreased by 48.5%, sleep disturbances by 50.1%, and depressive moods by 51.2%. Overall, the extract demonstrated a noticeable improvement in various alarming menopausal symptoms with minimal side effects, suggesting it could be a safe alternative for women seeking relief.
Read More
Vitamin E improves vaginal healthRetrospective Investigator-Initiated Trial on Tocopherol Acetate Vaginal Administration in Pre-and Postmenopausal Women.
High relevance for menopause management.
We examined the effects of tocopherol acetate, commonly known as vitamin E, on vaginal health for women navigating menopause. In our study, 50 women aged 50-70 were divided into menopausal and premenopausal groups and used specialized vaginal ovules for two weeks.
After treatment, we found that many distressing symptoms like dryness and pain during intercourse improved significantly. Additionally, the vaginal environment showed healthier changes, particularly in premenopausal women. Overall, tocopherol acetate may provide effective relief for those experiencing menopausal challenges.
Read More
Vitamin E aids menopause mood disordersAmeliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice.
Moderately relevant findings on treatment
We aimed to understand how vitamin E affects mood disorders linked to menopause, particularly in ovariectomized mice. Through behavioral tests, we noticed that vitamin E, specifically α-tocopherol and tocotrienol-rich palm oil extract, reduced signs of anxiety and depression in these mice.
While both treatments helped regulate stress hormone levels, tocotrienol-rich extract showed more promise than α-tocopherol in responding to chronic stress. Ultimately, our findings highlight the potential of vitamin E as a supportive treatment for menopause-related mood challenges.
Read More