Solgar Methylcobalamin (Vitamin B12)

We observed a compelling case surrounding the impact of vitamin B12 on anemia, particularly in a 62-year-old man facing severe deficiencies due to factors like drug use, hepatitis C, smoking, and alcoholism. Initially, this patient presented with symptoms such as fatigue, fever, and confusion, raising concerns about more critical conditions like thrombotic thrombocytopenic purpura (TTP). Laboratory tests indicated severe pancytopenia and signs of hemolysis, making the situation quite alarming.

However, further investigation revealed that the root cause was a significant deficiency of vitamin B12 coupled with folate. This discovery shifted our focus toward treatment strategies that addressed the underlying deficiency rather than applying unnecessary and invasive procedures like plasmapheresis. Upon administering vitamin B12 injections, we witnessed a refreshing turnaround as the patient's blood counts began to normalize progressively, along with an alleviation of symptoms.

This case emphasizes the necessity for healthcare providers to consider vitamin B12 deficiency when diagnosing patients presenting with hemolytic anemia and thrombocytopenia. By doing so, unnecessary treatments can be avoided, paving the way for a swift recovery through proper vitamin supplementation.

Life-saving solution

Most Useful Review

This product saved my life due to Pernicious Anemia. I experienced severe symptoms which worsened over time. I self-diagnosed after recalling symptoms of Vitamin B12 deficiency. After starting this product, my symptoms improved significantly, and I truly believe it helped me stay alive.

Back Pain details

SCIENTIFIC SCORE

Moderately Effective

Based on 16 Researches

Vitamin B12 aids low back pain

Vitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.

Most Relevant Research

We conducted a thorough investigation to understand whether intramuscular vitamin B12 treatment could effectively relieve low back pain. This study was designed as a double-blind, placebo-controlled trial involving 60 patients aged 18 to 65 who suffered from mechanical low back pain or sciatic neuritis. Each participant had a history of back pain lasting from six months to five years and reported significant pain intensity according to a standard scale.

By comparing two groups—the one receiving vitamin B12 injections and the other receiving a placebo—we focused on measuring changes in pain and disability levels, as well as any changes in paracetamol consumption. What we found was quite impressive. Both groups reported decreases in pain and disability. However, those who received vitamin B12 showed significantly better results compared to the placebo group. The difference was not only notable in terms of pain relief but also in lower dependency on paracetamol for pain management.

Our findings confirm that vitamin B12 can be a safe and effective option for patients with low back pain, particularly for those who don't have any signs of nutritional deficiency. The data suggest that patients experiencing this common ailment could consider discussing vitamin B12 treatment with their healthcare provider as part of their pain management strategy.

9.5

Pain relief achieved

Most Useful Review

I enjoyed the sweet taste after dinner. Most importantly, my back nerve pain has vanished.

Neuropathy details

SCIENTIFIC SCORE

Moderately Effective

Based on 13 Researches

Nitrous oxide affects B12 levels

Correlation Between Nitrous Oxide and Functional Vitamin B12 Deficiency Resulting in Subacute Combined Degeneration of the Spinal Cord: A Case Report.

Most Relevant Research

We examined a remarkable case involving the effects of nitrous oxide (NO) on vitamin B12 levels and its neurological consequences. Nitrous oxide is not just a useful tool in medical and food industries; it is sometimes misused by young adults for recreational purposes. This misuse can lead to functional vitamin B12 deficiency, which in turn may result in serious neurological issues like peripheral neuropathy and subacute combined degeneration (SACD) of the spinal cord.

In this specific case, we identified a functional B12 deficiency, characterized by borderline normal serum vitamin B12 levels, but with increased levels of methylmalonic acid and homocysteine—key indicators of vitamin deficiency. Remarkably, after administering intramuscular vitamin B12, we observed significant clinical improvement in the patient’s condition. This suggests that vitamin B12 treatment can be effective in reversing the neurological damage caused by nitrous oxide-induced deficiency.

Our findings highlight the importance of recognizing the neurological risks associated with nitrous oxide misuse and the potential for vitamin B12 treatment to alleviate serious symptoms in affected individuals.

8.3

Effective assistance provided

Most Useful Review

This definitely helps with neuropathy! It can be slightly overstimulating, so I recommend taking it before noon. I split the tablets in half, taking one before breakfast and the other before lunch, allowing them to dissolve under my tongue.

Insomnia details

SCIENTIFIC SCORE

Possibly Effective

Based on 7 Researches

Vitamin B12 promotes sleep in rats

Effects of intravenously administered vitamin B12 on sleep in the rat.

Most Relevant Research

We sought to determine the impact of vitamin B12 (VB12) on sleep patterns in rats, particularly considering its potential benefits for those struggling with insomnia. By giving rats a daily intravenous dose of VB12, we monitored their sleep using polysomnographic recordings over a four-day period.

During our observations, we noticed a significant increase in non-rapid eye movement (NREM) sleep on the second and third days of VB12 administration. Interestingly, REM sleep also showed a notable boost on the second day. The enhancements in sleep were particularly evident during the light period, indicating that vitamin B12 could play a role in promoting sleep at those times.

Additionally, we found that the rats receiving vitamin B12 exhibited serum levels that were 40 times higher than those in control rats, suggesting a robust absorption and impact of the vitamin. Overall, our findings indicate that administering VB12 peripherally does have positive effects on sleep in rats, especially during the light hours.

9.5

Improved mental health

Most Useful Review

Great for sleep and mental health. I had a severe B12 deficiency that significantly impacted my mental health. No doctor ruled it out until my mother suggested I check my blood serum level. My severe insomnia, extreme anxiety, and OCD completely disappeared after more than 16 shots of B12 1000mg methylcobalamin. My levels are now ideal at over 500 for good mental and nerve health. I feel energised, sleep well, and my anxiety has vanished. I take Solgar B12 three times a week to maintain this essential vitamin level. Solgar is a trustworthy brand; their supplement has worked well for me as I regularly monitor my blood levels.