Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.1
USERS' SCORE
Good
Based on 3 Reviews
8.3
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Taurine (Free Form)
500 mg
**
Top Medical Research Studies
9
We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
9
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
We explored the impact of taurine on spinal cord axon injury, particularly in the context of diabetic neuropathy, a common complication arising from diabetes mellitus. Using a rat model induced by streptozotocin—essentially a tool to mimic diabetes—we found that taurine significantly reduced axonal damage observed in the spinal cord.
Our analysis included both morphological and functional assessments, revealing that taurine not only ameliorated damage but also promoted neurite outgrowth in neurons exposed to high glucose levels. This suggests that taurine could play a beneficial role in repairing neural injuries associated with diabetes.
We also noted that taurine boosts the expression of nerve growth factor (NGF) and GAP-43, essential proteins for nerve growth and repair. The observed improvements seem linked to the activation of specific signaling pathways, namely the NGF-pAkt-mTOR axis. Interestingly, blocking this pathway with certain inhibitors dampened the positive effects of taurine, highlighting its crucial role in the protection and repair of neural tissues in diabetic conditions.
Overall, our findings indicate that taurine could be a promising therapeutic agent for enhancing spinal cord recovery from diabetic-induced injuries, providing hope for better management of diabetic neuropathy.
Our analysis included both morphological and functional assessments, revealing that taurine not only ameliorated damage but also promoted neurite outgrowth in neurons exposed to high glucose levels. This suggests that taurine could play a beneficial role in repairing neural injuries associated with diabetes.
We also noted that taurine boosts the expression of nerve growth factor (NGF) and GAP-43, essential proteins for nerve growth and repair. The observed improvements seem linked to the activation of specific signaling pathways, namely the NGF-pAkt-mTOR axis. Interestingly, blocking this pathway with certain inhibitors dampened the positive effects of taurine, highlighting its crucial role in the protection and repair of neural tissues in diabetic conditions.
Overall, our findings indicate that taurine could be a promising therapeutic agent for enhancing spinal cord recovery from diabetic-induced injuries, providing hope for better management of diabetic neuropathy.
Read More
Most Useful Reviews
7.5
Improved energy levels
5 people found this helpful
Great Taurine! I took it for my mother, and it helps her a lot. She doesn’t feel tired anymore and it aids in reducing sugar levels (she has type 2 diabetes). In a word, solid benefits.
Read More
9
Positive sugar reduction
1 people found this helpful
Taurine for sugar reduction worked wonders for my mum, who was diagnosed with diabetes. She followed a strict diet and started drinking Taurine as advised by Solgar. A month later, we observed positive results as her sugar levels began to decrease.
Read More
6
Supports diabetes management
Quality taurine from a reputable manufacturer is crucial for overall health. It is one of the most abundant amino acids, improving metabolism and protecting against conditions such as diabetes, neurological diseases, and more. It's essential to consult a doctor before taking dietary supplements.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 21 Researches
8.1
- All Researches
9.5
Intrarectal taurocholate improves diabetes markers
We explored the impact of intrarectal sodium taurocholate on hormone levels and glucose control in obese type 2 diabetic volunteers.
In a study with ten participants, we noted that higher doses of taurocholate led to significant increases in GLP-1, PYY, and insulin levels.
Remarkably, plasma glucose levels dropped, and participants consumed up to 47% less food after treatment.
This suggests that therapies boosting bile salts might help manage diabetes and obesity effectively.
In a study with ten participants, we noted that higher doses of taurocholate led to significant increases in GLP-1, PYY, and insulin levels.
Remarkably, plasma glucose levels dropped, and participants consumed up to 47% less food after treatment.
This suggests that therapies boosting bile salts might help manage diabetes and obesity effectively.
Read More
9
We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
9
We explored the role of taurine, a naturally occurring amino acid, in healing diabetic wounds. The study developed innovative patches that combine taurine with cerium dioxide, creating a unique treatment tool designed to tackle the challenges of wound healing in diabetes.
By using microneedle technology, these patches ensure that the beneficial components penetrate deep into the wound tissue. This method enhances the effectiveness of taurine, allowing it to help reduce oxidative stress and low-level inflammation commonly associated with non-healing diabetic wounds.
Our findings revealed that these specially designed patches not only stimulate healing but also improve the overall immune environment, making it easier for the body to repair damaged tissue. Ultimately, the approach harnesses taurine's antioxidant and anti-inflammatory properties, showing promising results in facilitating wound closure in diabetic patients.
Overall, the study highlights the potential of combining taurine with advanced delivery methods in overcoming obstacles to effective diabetic wound healing.
By using microneedle technology, these patches ensure that the beneficial components penetrate deep into the wound tissue. This method enhances the effectiveness of taurine, allowing it to help reduce oxidative stress and low-level inflammation commonly associated with non-healing diabetic wounds.
Our findings revealed that these specially designed patches not only stimulate healing but also improve the overall immune environment, making it easier for the body to repair damaged tissue. Ultimately, the approach harnesses taurine's antioxidant and anti-inflammatory properties, showing promising results in facilitating wound closure in diabetic patients.
Overall, the study highlights the potential of combining taurine with advanced delivery methods in overcoming obstacles to effective diabetic wound healing.
Read More
9
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
We delved into how taurine, paired with chitosan, can assist in healing wounds, especially in the context of diabetes. The study involved creating chitosan-taurine nanoparticles, which were then mixed into carboxymethyl chitosan hydrogels. This innovative combination aimed to enhance how well and how quickly wounds heal.
Our findings showed that these special hydrogel dressings not only supported better biodegradation and biocompatibility, but they also encouraged healing processes like angiogenesis—the formation of new blood vessels. The inclusion of taurine appears to have anti-inflammatory properties and promotes the movement and growth of cells essential for healing.
Importantly, tests on mice demonstrated that these dressings significantly improved wound healing in both acute and chronic diabetic conditions. We observed that the sustained release of taurine from the hydrogels has great potential for clinical applications in treating various types of wounds, making our study an exciting step forward in wound care.
Our findings showed that these special hydrogel dressings not only supported better biodegradation and biocompatibility, but they also encouraged healing processes like angiogenesis—the formation of new blood vessels. The inclusion of taurine appears to have anti-inflammatory properties and promotes the movement and growth of cells essential for healing.
Importantly, tests on mice demonstrated that these dressings significantly improved wound healing in both acute and chronic diabetic conditions. We observed that the sustained release of taurine from the hydrogels has great potential for clinical applications in treating various types of wounds, making our study an exciting step forward in wound care.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved energy levels
5 people found this helpful
Great Taurine! I took it for my mother, and it helps her a lot. She doesn’t feel tired anymore and it aids in reducing sugar levels (she has type 2 diabetes). In a word, solid benefits.
Read More
9
Positive sugar reduction
1 people found this helpful
Taurine for sugar reduction worked wonders for my mum, who was diagnosed with diabetes. She followed a strict diet and started drinking Taurine as advised by Solgar. A month later, we observed positive results as her sugar levels began to decrease.
Read More
6
Supports diabetes management
Quality taurine from a reputable manufacturer is crucial for overall health. It is one of the most abundant amino acids, improving metabolism and protecting against conditions such as diabetes, neurological diseases, and more. It's essential to consult a doctor before taking dietary supplements.
Read More
Frequently Asked Questions
9
Positive sugar reduction
1 people found this helpful
Taurine for sugar reduction worked wonders for my mum, who was diagnosed with diabetes. She followed a strict diet and started drinking Taurine as advised by Solgar. A month later, we observed positive results as her sugar levels began to decrease.
7.5
Improved energy levels
5 people found this helpful
Great Taurine! I took it for my mother, and it helps her a lot. She doesn’t feel tired anymore and it aids in reducing sugar levels (she has type 2 diabetes). In a word, solid benefits.
6
Supports diabetes management
Quality taurine from a reputable manufacturer is crucial for overall health. It is one of the most abundant amino acids, improving metabolism and protecting against conditions such as diabetes, neurological diseases, and more. It's essential to consult a doctor before taking dietary supplements.
8
We delved into the effects of cornel iridoid glycosides (CIG) on type 2 diabetes using a rat model. After inducing diabetes with a high-fat diet and streptozotocin, we examined various health indicators and conducted detailed metabolomic analyses of serum and urine.
Our findings suggested that CIG has significant antidiabetic effects, helping to control metabolic disorders in these diabetic rats. This research paves the way for clinical applications of CIG and enhances our understanding of its metabolic mechanisms.
Our findings suggested that CIG has significant antidiabetic effects, helping to control metabolic disorders in these diabetic rats. This research paves the way for clinical applications of CIG and enhances our understanding of its metabolic mechanisms.
8
Specialized milk improves diabetes outcomes
We aimed to assess the benefits of a specialized fermented milk product on patients with type 2 diabetes who also experience abdominal obesity. Over 21 days, 40 patients were divided into two groups; one consumed the milk product while the other did not.
Good tolerability was noted, and both groups experienced significant weight loss and improvements in body composition. However, those who consumed the milk product showcased even greater benefits, such as increased vitamin levels and improved markers for fat and carbohydrate metabolism. Overall, this specialized product can be a helpful addition to diet therapy for those managing diabetes.
Good tolerability was noted, and both groups experienced significant weight loss and improvements in body composition. However, those who consumed the milk product showcased even greater benefits, such as increased vitamin levels and improved markers for fat and carbohydrate metabolism. Overall, this specialized product can be a helpful addition to diet therapy for those managing diabetes.
7
TUDCA's Role in Diabetes Management
We undertook a study focused on tauroursodeoxycholic acid (TUDCA) and its potential role in managing diabetes, especially in individuals facing obesity. To understand how TUDCA works, we developed a method for measuring its presence in liver cells under specific conditions—hypothetically simulating a fatty diet.
Our findings revealed that TUDCA is capable of enhancing insulin clearance by promoting the expression of the insulin-degrading enzyme, which is critical for managing blood sugar levels. However, we noticed that in hyperlipidic conditions—characterized by high fat content—the concentration of TUDCA decreased. This suggests that its effectiveness at regulating blood sugar may be diminished in such environments.
The results prompt further investigation into TUDCA as a biomarker and a therapeutic option for type 2 diabetes and related conditions. Therefore, while we observed some promising effects of TUDCA in liver cells, the context of a high-fat environment appears to mitigate its benefits, signaling that more research is necessary to fully understand its implications in diabetes management.
Our findings revealed that TUDCA is capable of enhancing insulin clearance by promoting the expression of the insulin-degrading enzyme, which is critical for managing blood sugar levels. However, we noticed that in hyperlipidic conditions—characterized by high fat content—the concentration of TUDCA decreased. This suggests that its effectiveness at regulating blood sugar may be diminished in such environments.
The results prompt further investigation into TUDCA as a biomarker and a therapeutic option for type 2 diabetes and related conditions. Therefore, while we observed some promising effects of TUDCA in liver cells, the context of a high-fat environment appears to mitigate its benefits, signaling that more research is necessary to fully understand its implications in diabetes management.
8
We explored the impact of anthocyanins, specifically cyanidin-3-O-glucoside, on diabetic kidney disease (DKD). Through evaluating blood glucose and renal function, along with advanced metabolic analyses, we discovered that anthocyanins significantly reduced blood glucose levels and improved kidney function in treated mice compared to those not receiving treatment.
Our findings highlight that the benefits might stem from changes in amino acid metabolism. Incorporating dietary anthocyanins could be an effective strategy for preventing or managing DKD effectively.
Our findings highlight that the benefits might stem from changes in amino acid metabolism. Incorporating dietary anthocyanins could be an effective strategy for preventing or managing DKD effectively.
7
We examined how blood levels of taurine could interact with genetic factors to influence insulin sensitivity in overweight individuals on weight-loss diets.
In a two-year dietary trial with 711 participants, we measured genetic variants and blood taurine levels alongside improvements in glycemic traits.
While our findings suggest a potential role for taurine in modifying the effects of diabetes-related genes, the results underline a complex interplay rather than confirming significant overall benefits for diabetes management.
In a two-year dietary trial with 711 participants, we measured genetic variants and blood taurine levels alongside improvements in glycemic traits.
While our findings suggest a potential role for taurine in modifying the effects of diabetes-related genes, the results underline a complex interplay rather than confirming significant overall benefits for diabetes management.
References
- Hou Y, Huang Y, Shang Z, Ma S, Cui T, et al. Investigating the mechanism of cornel iridoid glycosides on type 2 diabetes mellitus using serum and urine metabolites in rats. J Ethnopharmacol. 2024;328:118065. doi:10.1016/j.jep.2024.118065
- Sharafetdinov KK, Novokshanova AL, Kochetkova AA, Plotnikova OA, Alekseeva RI, et al. [Assessment of the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders]. Vopr Pitan. 2024;93:67. doi:10.33029/0042-8833-2024-93-6-67-75
- Li YX, Lu YP, Tang D, Hu B, Zhang ZY, et al. Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism. J Transl Med. 2022;20:510. doi:10.1186/s12967-022-03717-9
- Tian J, Dang H, O'Laco KA, Song M, Tiu BC, et al. Homotaurine Treatment Enhances CD4 and CD8 Regulatory T Cell Responses and Synergizes with Low-Dose Anti-CD3 to Enhance Diabetes Remission in Type 1 Diabetic Mice. Immunohorizons. 2019;3:498. doi:10.4049/immunohorizons.1900019
- Zheng Y, Ceglarek U, Huang T, Wang T, Heianza Y, et al. Plasma Taurine, Diabetes Genetic Predisposition, and Changes of Insulin Sensitivity in Response to Weight-Loss Diets. J Clin Endocrinol Metab. 2016;101:3820.
- Abd El-Twab SM, Mohamed HM, Mahmoud AM. Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary-gonadal axis. Can J Physiol Pharmacol. 2016;94:651. doi:10.1139/cjpp-2015-0503
- Adrian TE, Gariballa S, Parekh KA, Thomas SA, Saadi H, et al. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia. 2012;55:2343. doi:10.1007/s00125-012-2593-2
- Song MK, Salam NK, Roufogalis BD, Huang TH. Lycium barbarum (Goji Berry) extracts and its taurine component inhibit PPAR-γ-dependent gene transcription in human retinal pigment epithelial cells: Possible implications for diabetic retinopathy treatment. Biochem Pharmacol. 2011;82:1209. doi:10.1016/j.bcp.2011.07.089
- Zeng K, Xu H, Chen K, Zhu J, Zhou Y, et al. Effects of taurine on glutamate uptake and degradation in Müller cells under diabetic conditions via antioxidant mechanism. Mol Cell Neurosci. 2010;45:192. doi:10.1016/j.mcn.2010.06.010
- Zeng K, Xu H, Mi M, Chen K, Zhu J, et al. Effects of taurine on glial cells apoptosis and taurine transporter expression in retina under diabetic conditions. Neurochem Res. 2010;35:1566. doi:10.1007/s11064-010-0216-1
- Gaamoussi F, Israili ZH, Lyoussi B. Hypoglycemic and hypolipidemic effects of an aqueous extract of Chamaerops humilis leaves in obese, hyperglycemic and hyperlipidemic Meriones shawi rats. Pak J Pharm Sci. 2010;23:212.
- Wang LJ, Yu YH, Zhang LG, Wang Y, Niu N, et al. Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: correlated with downregulation of LOX-1 and ICAM-1 expression on aortas. Eur J Pharmacol. 2008;597:75. doi:10.1016/j.ejphar.2008.08.031
- El-Akabawy G, Eid N. Enhancing metformin efficacy with cholecalciferol and taurine in diabetes therapy: Potential and limitations. World J Diabetes. 2025;16:100066. doi:10.4239/wjd.v16.i1.100066
- Tian S, Mei J, Zhang L, Wang S, Yuan Y, et al. Multifunctional Hydrogel Microneedle Patches Modulating Oxi-inflamm-aging for Diabetic Wound Healing. Small. 2024;20:e2407340. doi:10.1002/smll.202407340
- Attia MS, Ayman F, Attia MS, Yahya G, Zahra MH, et al. Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats. World J Diabetes. 2024;15:1778. doi:10.4239/wjd.v15.i8.1778
- Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity. Nature. 2024;633:182. doi:10.1038/s41586-024-07801-6
- Yuan J, Hou Q, He X, Zhong L, Li M, et al. Chitosan-taurine nanoparticles cross-linked carboxymethyl chitosan hydrogels facilitate both acute and chronic diabetic wound healing. Int J Biol Macromol. 2024;273:132762. doi:10.1016/j.ijbiomac.2024.132762
- Simões BES, Muniz MRR, Araujo TD, Magalhães Carneiro E, Simionato AVC. Evaluation of tauroursodeoxycholic acid in liver cells' cultures by MEKC: Initial hints to comprehend its role in diabetes mellitus of obese individuals. Electrophoresis. 2024;45:1252. doi:10.1002/elps.202300223
- Wang Y, Gao B, Chen X, Shi X, Li S, et al. Improvement of diabetes-induced spinal cord axon injury with taurine via nerve growth factor-dependent Akt/mTOR pathway. Amino Acids. 2024;56:32. doi:10.1007/s00726-024-03392-8
- Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. A PTER-dependent pathway of taurine metabolism linked to energy balance. bioRxiv. 2024. doi:10.1101/2024.03.21.586194
- Ouyang G, Wang N, Tong J, Sun W, Yang J, et al. Alleviation of taurine on liver injury of type 2 diabetic rats by improving antioxidant and anti-inflammatory capacity. Heliyon. 2024;10:e28400. doi:10.1016/j.heliyon.2024.e28400
