Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.1
USERS' SCORE
Good
Based on 7 Reviews
8.3
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Calories
15
Total Fat
1.5 g
2%**
Cholesterol
5 mg
2%
Total Omega 3 Polyunsaturates† providing: EPA (eicosapentaenoic acid) DHA (docosahexaenoic acid)
950 mg 504 mg378 mg
*** *** ***
Top Medical Research Studies
9.5
We conducted a 12-week randomized, double-blind clinical trial to evaluate the effects of eicosapentaenoic acid (EPA) on episodic migraine. Seventy participants were divided into two groups, one receiving EPA-rich fish oil and the other a placebo.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Read More
9.5
We analyzed various studies to see how effective high dosage omega-3 fatty acids, specifically EPA and DHA, are in preventing migraines. The results were quite promising!
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
Read More
8
We examined the effectiveness of daily 2000 mg eicosapentaenoic acid (EPA) supplementation in individuals suffering from chronic migraines. In a randomized, double-blind study, participants received either EPA or a placebo for eight weeks.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
Read More
Most Useful Reviews
7.5
Eases migraine symptoms
1 people found this helpful
The quality is strong and the ingredients are clean. The packaging is dark to protect against light. I really started to improve, with my skin seeming more moisturised and my fatigue decreasing by 50%. The migraine also eased.
Read More
9
Effective for migraine
GREAT! It normalises sleep with regular intake of 2 capsules and has improved my migraines. When the special effects begin, I take the pills as usual along with extra magnesium, and the migraine smoothly dissipates within a couple of hours, whereas before it would incapacitate me for half a day. The frequency of attacks has also declined, thanks in part to my medicinal support. Regular magnesium intake eases both PMS and menstruation, making the first day bearable without painkillers.
Read More
9
Excellent migraine impact
GREAT! It normalises sleep with regular intake of 2 capsules and improves my migraines. When I take the pills with added magnesium, the migraine disappears within a couple of hours, whereas before it would disable me for half a day. The frequency has diminished, and my medicinal support helps as well. I have noticed benefits from regular magnesium consumption during PMS and menstruation.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 17 Researches
7.1
- All Researches
9.5
We conducted a 12-week randomized, double-blind clinical trial to evaluate the effects of eicosapentaenoic acid (EPA) on episodic migraine. Seventy participants were divided into two groups, one receiving EPA-rich fish oil and the other a placebo.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Results showed that individuals taking EPA experienced a significant decrease in migraine frequency and severity compared to the placebo group. This included fewer migraine days and improved psychological well-being.
Notably, women appeared to benefit the most, highlighting EPA's potential as a promising preventive treatment for migraine.
Read More
9.5
We analyzed various studies to see how effective high dosage omega-3 fatty acids, specifically EPA and DHA, are in preventing migraines. The results were quite promising!
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
Read More
8
We examined the effectiveness of daily 2000 mg eicosapentaenoic acid (EPA) supplementation in individuals suffering from chronic migraines. In a randomized, double-blind study, participants received either EPA or a placebo for eight weeks.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
Read More
8
We examined the effects of omega-3 polyunsaturated fatty acids (OPFAω-3) on chronic migraine prevention. In a double-blind, controlled study, 60 patients were treated with amitriptyline, split into two groups—one receiving OPFAω-3 and the other a placebo. After 60 days, we discovered that 66.7% of those on omega-3 experienced a significant reduction in headache days, compared to just 33.3% in the placebo group. This suggests that omega-3 fish oil can be beneficial in reducing migraine frequency.
Read More
7
We aimed to understand how fish oil could impact migraine symptoms and blood lipids. In a study at Kuang Tian General Hospital, participants were given either fish oil or a placebo. After 12 weeks, those taking fish oil reported improved migraine frequency, duration, and pain intensity compared to the placebo group. Additionally, blood lipid levels showed significant reductions. This indicates that fish oil could be a helpful supplement for managing migraine symptoms and improving overall health.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Eases migraine symptoms
1 people found this helpful
The quality is strong and the ingredients are clean. The packaging is dark to protect against light. I really started to improve, with my skin seeming more moisturised and my fatigue decreasing by 50%. The migraine also eased.
Read More
9
Effective for migraine
GREAT! It normalises sleep with regular intake of 2 capsules and has improved my migraines. When the special effects begin, I take the pills as usual along with extra magnesium, and the migraine smoothly dissipates within a couple of hours, whereas before it would incapacitate me for half a day. The frequency of attacks has also declined, thanks in part to my medicinal support. Regular magnesium intake eases both PMS and menstruation, making the first day bearable without painkillers.
Read More
9
Excellent migraine impact
GREAT! It normalises sleep with regular intake of 2 capsules and improves my migraines. When I take the pills with added magnesium, the migraine disappears within a couple of hours, whereas before it would disable me for half a day. The frequency has diminished, and my medicinal support helps as well. I have noticed benefits from regular magnesium consumption during PMS and menstruation.
Read More
7.5
Prevents migraine onset
Omega is indispensable for me; I use it as a vital acid source and to prevent premenstrual migraines, often alongside vitamin E or evening primrose oil. It works excellently.
Read More
8
Good for migraines
Excellent! It's good for migraines.
Read More
Frequently Asked Questions
7
Reduces migraine occurrences
I buy this Omega repeatedly! Within a week, a visible result is noticeable: hair loss stops, migraines become less frequent, and my overall skin condition improves.
7.5
Supports migraine relief
This has been a staple product in my home for years. I ensure we never run out, or we feel the difference. I take it for mood support and give it to my children for ADD. For my 11-year-old, this significantly helps with migraines. It took the edge off his hyperactivity when he was younger. I recommend taking it daily for at least two weeks for effects to manifest.
9
Effective for migraine
GREAT! It normalises sleep with regular intake of 2 capsules and has improved my migraines. When the special effects begin, I take the pills as usual along with extra magnesium, and the migraine smoothly dissipates within a couple of hours, whereas before it would incapacitate me for half a day. The frequency of attacks has also declined, thanks in part to my medicinal support. Regular magnesium intake eases both PMS and menstruation, making the first day bearable without painkillers.
7.5
Eases migraine symptoms
1 people found this helpful
The quality is strong and the ingredients are clean. The packaging is dark to protect against light. I really started to improve, with my skin seeming more moisturised and my fatigue decreasing by 50%. The migraine also eased.
9
Excellent migraine impact
GREAT! It normalises sleep with regular intake of 2 capsules and improves my migraines. When I take the pills with added magnesium, the migraine disappears within a couple of hours, whereas before it would disable me for half a day. The frequency has diminished, and my medicinal support helps as well. I have noticed benefits from regular magnesium consumption during PMS and menstruation.
7.5
Prevents migraine onset
Omega is indispensable for me; I use it as a vital acid source and to prevent premenstrual migraines, often alongside vitamin E or evening primrose oil. It works excellently.
7
We aimed to understand how fish oil could impact migraine symptoms and blood lipids. In a study at Kuang Tian General Hospital, participants were given either fish oil or a placebo. After 12 weeks, those taking fish oil reported improved migraine frequency, duration, and pain intensity compared to the placebo group. Additionally, blood lipid levels showed significant reductions. This indicates that fish oil could be a helpful supplement for managing migraine symptoms and improving overall health.
8
We examined the effectiveness of daily 2000 mg eicosapentaenoic acid (EPA) supplementation in individuals suffering from chronic migraines. In a randomized, double-blind study, participants received either EPA or a placebo for eight weeks.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
Results indicated that EPA supplementation could help reduce the number of migraine attacks, lessen headache severity, and improve overall quality of life. So, while we see promise in this omega-3 fatty acid for migraine relief, further studies are warranted to determine its full potential.
9.5
We analyzed various studies to see how effective high dosage omega-3 fatty acids, specifically EPA and DHA, are in preventing migraines. The results were quite promising!
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
With 40 randomized controlled trials included, we found that these omega-3 supplements led to a significant decrease in both the frequency and severity of migraines compared to placebo.
Notably, they also had the highest acceptability rates among all treatments reviewed. This evidence suggests that high-dose omega-3s could be a top choice for migraine prevention.
5
We examined the potential of omega-3 fatty acids in treating migraine symptoms through a review of ten clinical studies from 2000 to early 2020. The studies suggest that omega-3s may help reduce inflammation, a key factor in migraine, but the evidence supporting their effectiveness is moderate and lacks consistency.
It’s essential to note that the quality of these studies varied, leaving us in need of further rigorous clinical trials to better understand the role of omega-3s in migraine management.
It’s essential to note that the quality of these studies varied, leaving us in need of further rigorous clinical trials to better understand the role of omega-3s in migraine management.
7
This study aimed to find out if eating more omega-3 fatty acids could help reduce headaches in the U.S. population.
Using data from over 12,000 adults, we found that those with higher intakes of omega-3s, specifically EPA and DHA, reported fewer severe headaches or migraines.
The results showed a slight but notable association between omega-3 intake and headache prevalence, particularly among non-Mexican Hispanic individuals.
Using data from over 12,000 adults, we found that those with higher intakes of omega-3s, specifically EPA and DHA, reported fewer severe headaches or migraines.
The results showed a slight but notable association between omega-3 intake and headache prevalence, particularly among non-Mexican Hispanic individuals.
References
- Yeh EL, Yang CP, Lin SW, Wang HF. Feasibility of Fish Oil Supplementation on Headache Symptoms and Blood Lipids in Migraine Patients. Brain Behav. 2024;14:e70149. 10.1002/brb3.70149
- Mohammadnezhad G, Assarzadegan F, Koosha M, Esmaily H. Eicosapentaenoic acid versus placebo as adjunctive therapy in chronic migraine: A randomized controlled trial. Headache. 2025;65:153. 10.1111/head.14808
- Wang HF, Liu WC, Zailani H, Yang CC, Chen TB, et al. A 12-week randomized double-blind clinical trial of eicosapentaenoic acid intervention in episodic migraine. Brain Behav Immun. 2024;118:459. 10.1016/j.bbi.2024.03.019
- Tseng PT, Zeng BY, Chen JJ, Kuo CH, Zeng BS, et al. High Dosage Omega-3 Fatty Acids Outperform Existing Pharmacological Options for Migraine Prophylaxis: A Network Meta-Analysis. Adv Nutr. 2024;15:100163. 10.1016/j.advnut.2023.100163
- Djalali M, Talebi S, Djalali E, Abdolahi M, Travica N, et al. The effect of omega-3 fatty acids supplementation on inflammatory biomarkers in subjects with migraine: a randomized, double-blind, placebo-controlled trial. Immunopharmacol Immunotoxicol. 2023;45:565. 10.1080/08923973.2023.2196600
- Faurot KR, Cole WR, MacIntosh BA, Dunlap M, Moore CB, et al. Targeted dietary interventions to reduce pain in persistent post-traumatic headache among service members: Protocol for a randomized, controlled parallel-group trial. Contemp Clin Trials. 2022;119:106851. 10.1016/j.cct.2022.106851
- Ramsden CE, Zamora D, Faurot KR, MacIntosh B, Horowitz M, et al. Dietary alteration of n-3 and n-6 fatty acids for headache reduction in adults with migraine: randomized controlled trial. BMJ. 2021;374:n1448. 10.1136/bmj.n1448
- Abdolahi M, Karimi E, Sarraf P, Tafakhori A, Siri G, et al. The omega-3 and Nano-curcumin effects on vascular cell adhesion molecule (VCAM) in episodic migraine patients: a randomized clinical trial. BMC Res Notes. 2021;14:283. 10.1186/s13104-021-05700-x
- Cardia L, Calapai F, Mondello C, Quattrone D, Elisa Sorbara E, et al. Clinical use of omega-3 fatty acids in migraine: A narrative review. Medicine (Baltimore). 2020;99:e22253. 10.1097/MD.0000000000022253
- Honarvar NM, Soveid N, Abdolahi M, Djalali M, Hatami M, et al. Anti-Neuroinflammatory Properties of n-3 Fatty Acids and Nano- Curcumin on Migraine Patients from Cellular to Clinical Insight: A Randomized, Double-Blind and Placebo-Controlled Trial. Endocr Metab Immune Disord Drug Targets. 2021;21:365. 10.2174/1871530320666200729144430
- Abdolahi M, Jafarieh A, Sarraf P, Sedighiyan M, Yousefi A, et al. The Neuromodulatory Effects of ω-3 Fatty Acids and Nano-Curcumin on the COX-2/ iNOS Network in Migraines: A Clinical Trial Study from Gene Expression to Clinical Symptoms. Endocr Metab Immune Disord Drug Targets. 2019;19:874. 10.2174/1871530319666190212170140
- Sanders AE, Shaikh SR, Slade GD. Long-chain omega-3 fatty acids and headache in the U.S. population. Prostaglandins Leukot Essent Fatty Acids. 2018;135:47. 10.1016/j.plefa.2018.06.008
- Soveyd N, Abdolahi M, Djalali M, Hatami M, Tafakhori A, et al. The Combined Effects of ω -3 Fatty Acids and Nano-Curcumin Supplementation on Intercellular Adhesion Molecule-1 (ICAM-1) Gene Expression and Serum Levels in Migraine Patients. CNS Neurol Disord Drug Targets. 2018;16:1120. 10.2174/1871527317666171213154749
- Maghsoumi-Norouzabad L, Mansoori A, Abed R, Shishehbor F. Effects of omega-3 fatty acids on the frequency, severity, and duration of migraine attacks: A systematic review and meta-analysis of randomized controlled trials. Nutr Neurosci. 2018;21:614. 10.1080/1028415X.2017.1344371
- Abdolahi M, Tafakhori A, Togha M, Okhovat AA, Siassi F, et al. The synergistic effects of ω-3 fatty acids and nano-curcumin supplementation on tumor necrosis factor (TNF)-α gene expression and serum level in migraine patients. Immunogenetics. 2017;69:371. 10.1007/s00251-017-0992-8
- Soares AA, Louçana PMC, Nasi EP, Sousa KMH, Sá OMS, et al. A double- blind, randomized, and placebo-controlled clinical trial with omega-3 polyunsaturated fatty acids (OPFA ɷ-3) for the prevention of migraine in chronic migraine patients using amitriptyline. Nutr Neurosci. 2018;21:219. 10.1080/1028415X.2016.1266133
- Pradalier A, Bakouche P, Baudesson G, Delage A, Cornaille-Lafage G, et al. Failure of omega-3 polyunsaturated fatty acids in prevention of migraine: a double-blind study versus placebo. Cephalalgia. 2001;21:818.
