Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%
Top Medical Research Studies
7
We explored the effects of pyridoxine, a form of vitamin B6, on skin health, focusing particularly on its potential benefits for those struggling with acne. Our research indicates that pyridoxine plays a significant role in maintaining the function of the epidermis, the outermost layer of our skin.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Read More
Most Useful Reviews
7.5
Prevents acne
I take it to prevent acne and enhance my metabolism.
Read More
7.5
Great for skin
I love taking this alongside zinc every morning. Not only does it support immune health, but it’s fantastic for skin health! I have acne, and these two products work excellently together.
Read More
7.5
Works for acne
It appears to be effective for acne. I purchased it as a beauty product.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
We explored the effects of pyridoxine, a form of vitamin B6, on skin health, focusing particularly on its potential benefits for those struggling with acne. Our research indicates that pyridoxine plays a significant role in maintaining the function of the epidermis, the outermost layer of our skin.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.5
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Prevents acne
I take it to prevent acne and enhance my metabolism.
Read More
7.5
Great for skin
I love taking this alongside zinc every morning. Not only does it support immune health, but it’s fantastic for skin health! I have acne, and these two products work excellently together.
Read More
7.5
Works for acne
It appears to be effective for acne. I purchased it as a beauty product.
Read More
0
Not effective choice
3 people found this helpful
After a lifetime of relying on the pharmacy MAGNE B6 FORTE without success, I turned to iHerb for a similar product. I spent considerable time researching magnesium forms (citrate, chelate, etc.) and decided on Doctors Best magnesium chelate, supplemented with vitamin B6 from Solgar. However, after just a week, I developed side effects, including blisters (acne on my face) and abdominal heaviness. I'm unsure whether the magnesium or B6 was the cause, so I have decided to return to pharmacy MAGNE B6 for the time being.
Read More
Frequently Asked Questions
7.5
Great for skin
I love taking this alongside zinc every morning. Not only does it support immune health, but it’s fantastic for skin health! I have acne, and these two products work excellently together.
0
Not effective choice
3 people found this helpful
After a lifetime of relying on the pharmacy MAGNE B6 FORTE without success, I turned to iHerb for a similar product. I spent considerable time researching magnesium forms (citrate, chelate, etc.) and decided on Doctors Best magnesium chelate, supplemented with vitamin B6 from Solgar. However, after just a week, I developed side effects, including blisters (acne on my face) and abdominal heaviness. I'm unsure whether the magnesium or B6 was the cause, so I have decided to return to pharmacy MAGNE B6 for the time being.
7.5
Works for acne
It appears to be effective for acne. I purchased it as a beauty product.
7
We explored the effects of pyridoxine, a form of vitamin B6, on skin health, focusing particularly on its potential benefits for those struggling with acne. Our research indicates that pyridoxine plays a significant role in maintaining the function of the epidermis, the outermost layer of our skin.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
Through our examination of normal human epidermal keratinocytes, we observed that pyridoxine enhances the expression of profilaggrin mRNA, a precursor to filaggrin—a key protein involved in skin hydration and barrier function. The results show that treatment with pyridoxine leads to an increased production of filaggrin protein, and this effect is concentration-dependent.
While the study did not isolate findings specifically focused on treating acne alone, the increase in filaggrin production suggests that vitamin B6 might contribute positively to skin conditions related to dryness and irritation, which often accompany acne-prone skin. Our findings suggest that pyridoxine could be a valuable daily care ingredient for those with atopic dermatitis or skin issues associated with low filaggrin levels.
References
- Fujishiro M, Yahagi S, Takemi S, Nakahara M, Sakai T, et al. Pyridoxine stimulates filaggrin production in human epidermal keratinocytes. Mol Biol Rep. 2021;48:5513. doi:10.1007/s11033-021-06563-y
