Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
USERS' SCORE
Good
Based on 4 Reviews
8.8
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as pyridoxine HCl)
25 mg
1,471%

Top Medical Research Studies

9
Vitamin B6 could aid insomnia
We set out to investigate how vitamin B6 contributes to improving sleep quality in individuals experiencing mild to moderate insomnia. Our study involved 40 participants who were given a combination treatment containing melatonin, vitamin B6, and extracts from various medicinal plants.

Over a period of two weeks, participants documented their sleep experiences using a daily electronic diary. We analyzed changes in sleep quality, total sleep duration, and how well our treatment reduced sleep-related daytime impairments. Encouragingly, participants reported a significant improvement in sleep quality, with an average score rise from 5.4 to 7.3 on a 10-point scale.

Although it is difficult to isolate the specific effects of vitamin B6 alone due to its use alongside other ingredients, our findings do suggest that this vitamin, when combined with melatonin and plant extracts, could support better sleep. Importantly, the treatment was well-tolerated, with no serious side effects reported.

Overall, while vitamin B6 on its own wasn’t examined, its inclusion in a combination treatment appears to play a role in enhancing sleep quality for those struggling with insomnia.
Read More
We investigated how a supplement containing magnesium, melatonin, and vitamin B6 impacts insomnia. The study involved 60 patients diagnosed with insomnia, who were split into a study group and a control group.

The study group received a daily dose of this supplement for three months, while both groups reported their insomnia severity using the Athens Insomnia Scale. Initially, the two groups showed similar scores, indicating mild to moderate insomnia.

After the three-month period, the results were telling. The study group reported a significant improvement, lowering their average insomnia score to mild levels, while the control group remained at moderate insomnia levels. However, it’s essential to note that while vitamin B6 was part of the supplement, we cannot conclusively state its isolated effect on insomnia treatment due to the combination with magnesium and melatonin.

Overall, the findings suggest that magnesium, melatonin, and vitamin B6 together can effectively alleviate insomnia symptoms, benefiting those struggling with sleep issues, regardless of the cause.
Read More
7
Vitamin B6's unclear insomnia effect
We observed that vitamin B6 deficiency might contribute to insomnia in patients suffering from acute intermittent porphyria (AIP). In a study involving several patients, insomnia was one of the notable symptoms experienced during acute attacks. While vitamin B6 was included in the treatment plan, its isolated effectiveness on insomnia couldn't be precisely determined because it was part of a broader therapeutic approach.

Patients received various treatments, including glucose, sodium chloride, and even phenothiazines, making it difficult to pinpoint whether vitamin B6 alone helped alleviate insomnia. Additionally, the overall improvement seen in these patients suggests that their recovery may result from a combination of therapies rather than solely from vitamin B6 itself. It’s essential to recognize that while vitamin B6 was part of the treatment strategy, we cannot conclusively say it specifically addressed insomnia with the information available.
Read More

Most Useful Reviews

10
Sleeping pill alternative
Excellent sleep aid! I had no idea a low dose of B6 in the evening could improve my sleep so much. After suffering from insomnia for over a decade, I used to manage about four hours a night, even with sleeping pills. Now, I’ve been able to cease taking them altogether, and I average about seven to eight hours of solid sleep!
Read More
8.8
Improved insomnia symptoms
I take half a tablet of B6 at night with 1000 mg of GABA, as I read in a medical journal that B6 enhances GABA's effectiveness. This seems to improve my insomnia more than GABA alone.
Read More
9.5
Soothed nerves
I combine B6 with magnesium, which calms my nervous system and regulates my sleep patterns. My blood pressure is normal as well. If anyone is dealing with nervous tics, panic attacks, blood pressure issues, insomnia, or psychological stress, I highly recommend this combination.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 3 Researches
8
  • All Researches
9
Vitamin B6 could aid insomnia
We set out to investigate how vitamin B6 contributes to improving sleep quality in individuals experiencing mild to moderate insomnia. Our study involved 40 participants who were given a combination treatment containing melatonin, vitamin B6, and extracts from various medicinal plants.

Over a period of two weeks, participants documented their sleep experiences using a daily electronic diary. We analyzed changes in sleep quality, total sleep duration, and how well our treatment reduced sleep-related daytime impairments. Encouragingly, participants reported a significant improvement in sleep quality, with an average score rise from 5.4 to 7.3 on a 10-point scale.

Although it is difficult to isolate the specific effects of vitamin B6 alone due to its use alongside other ingredients, our findings do suggest that this vitamin, when combined with melatonin and plant extracts, could support better sleep. Importantly, the treatment was well-tolerated, with no serious side effects reported.

Overall, while vitamin B6 on its own wasn’t examined, its inclusion in a combination treatment appears to play a role in enhancing sleep quality for those struggling with insomnia.
Read More
We investigated how a supplement containing magnesium, melatonin, and vitamin B6 impacts insomnia. The study involved 60 patients diagnosed with insomnia, who were split into a study group and a control group.

The study group received a daily dose of this supplement for three months, while both groups reported their insomnia severity using the Athens Insomnia Scale. Initially, the two groups showed similar scores, indicating mild to moderate insomnia.

After the three-month period, the results were telling. The study group reported a significant improvement, lowering their average insomnia score to mild levels, while the control group remained at moderate insomnia levels. However, it’s essential to note that while vitamin B6 was part of the supplement, we cannot conclusively state its isolated effect on insomnia treatment due to the combination with magnesium and melatonin.

Overall, the findings suggest that magnesium, melatonin, and vitamin B6 together can effectively alleviate insomnia symptoms, benefiting those struggling with sleep issues, regardless of the cause.
Read More
7
Vitamin B6's unclear insomnia effect
We observed that vitamin B6 deficiency might contribute to insomnia in patients suffering from acute intermittent porphyria (AIP). In a study involving several patients, insomnia was one of the notable symptoms experienced during acute attacks. While vitamin B6 was included in the treatment plan, its isolated effectiveness on insomnia couldn't be precisely determined because it was part of a broader therapeutic approach.

Patients received various treatments, including glucose, sodium chloride, and even phenothiazines, making it difficult to pinpoint whether vitamin B6 alone helped alleviate insomnia. Additionally, the overall improvement seen in these patients suggests that their recovery may result from a combination of therapies rather than solely from vitamin B6 itself. It’s essential to recognize that while vitamin B6 was part of the treatment strategy, we cannot conclusively say it specifically addressed insomnia with the information available.
Read More

User Reviews

USERS' SCORE
Good
Based on 4 Reviews
8.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Sleeping pill alternative
Excellent sleep aid! I had no idea a low dose of B6 in the evening could improve my sleep so much. After suffering from insomnia for over a decade, I used to manage about four hours a night, even with sleeping pills. Now, I’ve been able to cease taking them altogether, and I average about seven to eight hours of solid sleep!
Read More
8.8
Improved insomnia symptoms
I take half a tablet of B6 at night with 1000 mg of GABA, as I read in a medical journal that B6 enhances GABA's effectiveness. This seems to improve my insomnia more than GABA alone.
Read More
9.5
Soothed nerves
I combine B6 with magnesium, which calms my nervous system and regulates my sleep patterns. My blood pressure is normal as well. If anyone is dealing with nervous tics, panic attacks, blood pressure issues, insomnia, or psychological stress, I highly recommend this combination.
Read More
9.5
Beneficial combination
I have struggled with insomnia for years. This product has proven very beneficial for me, especially when combined with Oryzanol.
Read More

Frequently Asked Questions

Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.

Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.

B6, also known as pyridoxine, is a water-soluble vitamin that plays a vital role in numerous physiological functions within the body. It is essential for the metabolism of proteins, carbohydrates, and fats, and is involved in the synthesis of neurotransmitters, which are critical for proper brain function and mood regulation. B6 also contributes to the production of hemoglobin, which is necessary for transporting oxygen in the blood, and aids in the maintenance of healthy immune function.

Most people can obtain sufficient B6 through a balanced diet that includes foods like poultry, fish, potatoes, chickpeas, bananas, and fortified cereals. However, some individuals may benefit from supplementation, particularly those with specific health conditions, dietary restrictions, or higher nutritional needs. The recommended dietary allowance (RDA) varies by age and gender, so it’s important to pay attention to your individual needs. Although B6 is generally safe, high doses from supplements can lead to side effects, so it’s always best to consult with a healthcare provider if you’re considering adding pyridoxine to your regimen.

While vitamin B6, specifically pyridoxine, plays a crucial role in many bodily functions—including the conversion of tryptophan to serotonin, a precursor to the sleep hormone melatonin—its direct effect on insomnia isn't definitively established. Some studies indicate that higher levels of vitamin B6 might be associated with improved sleep quality, as it can help to regulate neurotransmitters, which are important for sleep regulation. However, most research emphasizes a balanced diet rich in various vitamins and minerals instead of focusing on individual supplements.

If you're struggling with insomnia, it's essential to consider multiple factors that contribute to sleep disturbances, such as lifestyle, stress, and other health conditions. While B6 can be part of a healthy sleep-friendly diet, it’s recommended to consult with a healthcare professional before starting any supplement regimen. They can help evaluate your specific situation and determine whether pyridoxine or other interventions might be beneficial for enhancing sleep quality.

Based on user reviews, the time it takes to see results from this supplement for insomnia can vary. Some users report that they experience noticeable improvements in their sleep patterns shortly after beginning the supplement, particularly when it is combined with other supportive nutrients like magnesium and Oryzanol. For instance, one user mentioned that they find this product to be very beneficial for their long-standing insomnia issues ((Read Review)).

This supplement, particularly those containing a combination of melatonin, magnesium, and vitamin B6, shows promise in alleviating insomnia symptoms. A study involving 60 patients revealed that after three months of daily supplementation, those taking the combination reported a significant improvement in their insomnia severity compared to a control group, suggesting that this combination could effectively reduce insomnia symptoms for individuals struggling with sleep challenges [1]. Additionally, another study examined how a similar combination treatment, including melatonin, vitamin B6, and herbal extracts, resulted in participants reporting an improved sleep quality, demonstrating the potential advantages of including vitamin B6 in a supplement regimen tailored for insomnia [2].

However, it's important to note that while these studies highlight the positive effects of the combinations, they do not isolate the effects of vitamin B6 alone, making it challenging to attribute the sleep benefits solely to this vitamin. Thus, although the combination of these ingredients appears beneficial for insomnia, further research is needed to fully determine the specific role of vitamin B6 as an isolated treatment option [3]. For anyone considering supplementation for insomnia, it's advisable to consult with a healthcare professional to find a personalized approach.

Users report a range of improvements in symptoms associated with sleep and overall nervous system regulation after using this supplement. For instance, one user shared that by combining B6 with magnesium, they experienced calmer nerves, better sleep patterns, and normalized blood pressure, which could be particularly useful for those dealing with conditions like nervous tics, panic attacks, or psychological stress ((Read Review)). Another user, who struggled with insomnia for years, mentioned that this product significantly improved their sleep issues, highlighting the benefits of combining it with Oryzanol ((Read Review)). Such anecdotal experiences suggest that while individual results may vary, many users find value in this supplement for enhancing their sleep and managing anxiety-related symptoms.

Users report positive experiences when combining this supplement with other nutrients to manage insomnia. For instance, one user noted that incorporating B6 with magnesium not only calmed their nervous system but also helped regulate sleep patterns and normalize blood pressure. They highly recommend this combination for those dealing with various sleep-related and anxiety issues, indicating that it could be particularly beneficial for conditions like nervous tics, panic attacks, or psychological stress ((Read Review)).

Similarly, another user emphasized the effectiveness of this supplement for long-term insomnia when paired with Oryzanol, noting significant improvements in their sleep quality. These testimonials suggest that users frequently find enhanced results and a better overall experience with sleep by strategically combining this supplement with other supportive ingredients, ultimately underscoring the potential value of such combinations in addressing insomnia and related symptoms ((Read Review)).

Based on user reviews, many individuals report positive results from taking B6 Pyridoxine for treating insomnia, especially when paired with other supplements. One user noted that combining B6 with magnesium significantly calmed their nervous system and helped regulate sleep patterns, which they found effective for not just insomnia but also for managing anxiety-related symptoms such as panic attacks and nervous tics (Read Review). Another review highlights the benefits of B6 in conjunction with Oryzanol, indicating that this combination has proven beneficial for long-standing insomnia issues (Read Review).

While specific dosage recommendations were not provided in the reviews, the emphasis on combining B6 with other calming supplements suggests that users may find enhanced effectiveness through such combinations. It seems that individual experiences vary, and finding the right dose may depend on personal health needs and other factors. Overall, the reports indicate that B6 Pyridoxine can play a useful role in supporting better sleep when used judiciously with complementary nutrients.

9.5
Beneficial combination
I have struggled with insomnia for years. This product has proven very beneficial for me, especially when combined with Oryzanol.
9.5
Soothed nerves
I combine B6 with magnesium, which calms my nervous system and regulates my sleep patterns. My blood pressure is normal as well. If anyone is dealing with nervous tics, panic attacks, blood pressure issues, insomnia, or psychological stress, I highly recommend this combination.
We investigated how a supplement containing magnesium, melatonin, and vitamin B6 impacts insomnia. The study involved 60 patients diagnosed with insomnia, who were split into a study group and a control group.

The study group received a daily dose of this supplement for three months, while both groups reported their insomnia severity using the Athens Insomnia Scale. Initially, the two groups showed similar scores, indicating mild to moderate insomnia.

After the three-month period, the results were telling. The study group reported a significant improvement, lowering their average insomnia score to mild levels, while the control group remained at moderate insomnia levels. However, it’s essential to note that while vitamin B6 was part of the supplement, we cannot conclusively state its isolated effect on insomnia treatment due to the combination with magnesium and melatonin.

Overall, the findings suggest that magnesium, melatonin, and vitamin B6 together can effectively alleviate insomnia symptoms, benefiting those struggling with sleep issues, regardless of the cause.
9
Vitamin B6 could aid insomnia
We set out to investigate how vitamin B6 contributes to improving sleep quality in individuals experiencing mild to moderate insomnia. Our study involved 40 participants who were given a combination treatment containing melatonin, vitamin B6, and extracts from various medicinal plants.

Over a period of two weeks, participants documented their sleep experiences using a daily electronic diary. We analyzed changes in sleep quality, total sleep duration, and how well our treatment reduced sleep-related daytime impairments. Encouragingly, participants reported a significant improvement in sleep quality, with an average score rise from 5.4 to 7.3 on a 10-point scale.

Although it is difficult to isolate the specific effects of vitamin B6 alone due to its use alongside other ingredients, our findings do suggest that this vitamin, when combined with melatonin and plant extracts, could support better sleep. Importantly, the treatment was well-tolerated, with no serious side effects reported.

Overall, while vitamin B6 on its own wasn’t examined, its inclusion in a combination treatment appears to play a role in enhancing sleep quality for those struggling with insomnia.
7
Vitamin B6's unclear insomnia effect
We observed that vitamin B6 deficiency might contribute to insomnia in patients suffering from acute intermittent porphyria (AIP). In a study involving several patients, insomnia was one of the notable symptoms experienced during acute attacks. While vitamin B6 was included in the treatment plan, its isolated effectiveness on insomnia couldn't be precisely determined because it was part of a broader therapeutic approach.

Patients received various treatments, including glucose, sodium chloride, and even phenothiazines, making it difficult to pinpoint whether vitamin B6 alone helped alleviate insomnia. Additionally, the overall improvement seen in these patients suggests that their recovery may result from a combination of therapies rather than solely from vitamin B6 itself. It’s essential to recognize that while vitamin B6 was part of the treatment strategy, we cannot conclusively say it specifically addressed insomnia with the information available.

References

  1. Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. doi:10.3889/oamjms.2019.771
  2. Lemoine P, Bablon JC, Da Silva C. A combination of melatonin, vitamin B6 and medicinal plants in the treatment of mild-to-moderate insomnia: A prospective pilot study. Complement Ther Med. 2019;45:104. doi:10.1016/j.ctim.2019.05.024
  3. Mydlík M, Derzsiová K. Kidney damage in acute intermittent porphyria. Przegl Lek. 2011;68:610.
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