Last update
4/17/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 7 Reviews
8.6
Supplement Facts
Serving Size: 1 Vegetable Capsule
Amount Per Serving
%DV
Vitamin C (as L-ascorbic acid)
1,000 mg
1,111%
Top Medical Research Studies
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
Most Useful Reviews
9
No heartburn experience
I regularly consume this product. Just one pill suffices for the day's intake, and I experience no heartburn, even when taken on an empty stomach.
Read More
9
Immunity boost without heartburn
This product is of excellent quality and adequately sized, meaning I don't have to repurchase it often. I chose it for the ingredients, and it has effectively boosted my immunity whilst causing no heartburn.
Read More
9
Supports immunity
This is the best vitamin C I've used, with a very convenient dosage that causes no heartburn, yet effectively supports my immunity.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
No heartburn experience
I regularly consume this product. Just one pill suffices for the day's intake, and I experience no heartburn, even when taken on an empty stomach.
Read More
9
Immunity boost without heartburn
This product is of excellent quality and adequately sized, meaning I don't have to repurchase it often. I chose it for the ingredients, and it has effectively boosted my immunity whilst causing no heartburn.
Read More
9
Supports immunity
This is the best vitamin C I've used, with a very convenient dosage that causes no heartburn, yet effectively supports my immunity.
Read More
9
Gentle on stomach
This mild vitamin C does not trigger heartburn, which is crucial for me. I take it alongside iron and am very satisfied as it lasts a long time.
Read More
9
No heartburn experienced
I will continue using Sole Vitamin C 1000 Bezip Cap. Unlike others, the white powder is in capsules, so I can easily check its oxidation. I take one with each meal, and I do not experience heartburn. I will aim for higher efficacy.
Read More
Frequently Asked Questions
9
Less tired feeling
I have had no heartburn, and feel really good; I'm definitely less tired.
7
Effective for heartburn
I bought it for heartburn, and it seems to work well. I will continue to eat it.
9
No heartburn experience
I regularly consume this product. Just one pill suffices for the day's intake, and I experience no heartburn, even when taken on an empty stomach.
9
Immunity boost without heartburn
This product is of excellent quality and adequately sized, meaning I don't have to repurchase it often. I chose it for the ingredients, and it has effectively boosted my immunity whilst causing no heartburn.
9
No heartburn experienced
I will continue using Sole Vitamin C 1000 Bezip Cap. Unlike others, the white powder is in capsules, so I can easily check its oxidation. I take one with each meal, and I do not experience heartburn. I will aim for higher efficacy.
9
Gentle on stomach
This mild vitamin C does not trigger heartburn, which is crucial for me. I take it alongside iron and am very satisfied as it lasts a long time.
8
Vitamin C reduces heartburn symptoms
We investigated how vitamin C, specifically in the form of a 2% vitamin C solution spray, could help alleviate heartburn symptoms following Lugol chromoendoscopy, a procedure that involves staining the esophagus to better visualize abnormalities. In a well-structured study with 240 participants, we used a randomized, double-blind approach to compare the effectiveness of vitamin C to normal saline and sodium thiosulfate solutions.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
Our results showed that vitamin C spray significantly reduced both acute heartburn symptoms and late discomfort when compared to the saline solution. Specifically, 33% of participants using vitamin C reported relief from acid regurgitation or heartburn, compared to just 15% with sodium thiosulfate. Additionally, patients noted an improvement in retrosternal pain, with 21% finding relief from the vitamin C treatment versus 9% from sodium thiosulfate.
Furthermore, vitamin C offered a quicker discoloration of the iodine-stained mucosa compared to saline, enhancing the overall experience of the procedure. These findings suggest that incorporating vitamin C spray into post-procedural care could be a helpful strategy for patients facing discomfort after undergoing Lugol chromoendoscopy.
References
- Jin D, Wang J, Zhan Q, Huang K, Wang H, et al. The safety and efficacy of 2% vitamin C solution spray for relief of mucosal irritation caused by Lugol chromoendoscopy: a multicenter, randomized, double-blind, parallel trial. Gastrointest Endosc. 2020;92:554. 10.1016/j.gie.2019.11.028
