'
SCIENTIFIC SCORE
Most Likely Effective
Based on 3 Researches
8.3
USERS' SCORE
Excellent
Based on 2 Reviews
9.5
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Vitamin E (as d-Alpha Tocopherol)
670 mg
4,467%
Mixed Tocopherols (providing d-Gamma, d-Delta and d-Beta Tocopherols)
35 mg
**

Top Medical Research Studies

8
Vitamin E enhances vaginal health
Retrospective Investigator-Initiated Trial on Tocopherol Acetate Vaginal Administration in Pre-and Postmenopausal Women.
Directly addresses menopause treatment
We examined how tocopherol acetate, commonly known as vitamin E, affects vaginal health in women experiencing menopause and those who are premenopausal. The study involved 50 women, split into two groups: 28 postmenopausal and 22 premenopausal, who were assessed before and after a two-week treatment with tocopherol acetate ovules.

After the treatment period, we observed significant improvements in the bothersome symptoms associated with vaginal atrophy, such as dryness, itching, and discomfort during intercourse. Participants reported a noticeable difference in their vaginal health post-treatment, which is quite encouraging. Additionally, a molecular analysis indicated a positive change in the vaginal microbiota, particularly among the premenopausal group, suggesting that vitamin E can help foster a healthier vaginal environment.

Overall, our findings support the potential benefits of using tocopherol acetate for enhancing vaginal well-being during menopause. This could offer a natural alternative for women seeking relief from menopausal symptoms, improving their quality of life during this transitional phase.
Read More
8
Vitamin E may improve menopausal mood
Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice.
Directly addresses vitamin E's effects
We evaluated the impact of vitamin E on mood disorders associated with menopause, particularly focusing on symptoms like anxiety and depression in a mouse model. The study involved ovariectomized mice to simulate estrogen deficiency, a key factor influencing menopause-related mood changes.

Our findings revealed that these mice exhibited behaviors typical of depression and anxiety, along with higher levels of corticosterone, a hormone linked to stress. We administered α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract over 14 days to see if they could alleviate these symptoms.

Remarkably, both treatments helped improve behavior in various tests designed to assess anxiety and depression. Notably, tocotrienol-rich palm oil extract showed additional benefits in mice subjected to chronic stress, effectively altering their emotional responses. Importantly, both treatments also led to reductions in elevated stress hormone levels.

These results suggest that vitamin E, through both α-tocopherol and tocotrienol-rich extracts, may help alleviate mood disorders linked to menopause by modulating the body's stress response. This could pave the way for new treatments to support women's psychological well-being during this challenging life stage.
Read More
9
Effectiveness of Ozoile Treatment
Stable Ozonides plus Vitamin E Acetate (Ozoile) for Treatment of Genitourinary Syndrome.
Limited significance in isolating vitamin E
We assessed the impact of a combination treatment using stable ozonides and vitamin E acetate, called Ozoile, on symptoms associated with genitourinary syndrome, commonly seen in menopause. This syndrome results from decreased estrogen levels, leading to discomfort in the genitourinary tract. Women experiencing symptoms like dryness, burning, and pain participated in our study over a period of 20 days.

The results were promising. We observed a significant reduction in pain, with the occurrence dropping from 16.7% to 11.8%. Additionally, the average intensity of symptoms showed a notable decrease—from 2.10 pre-treatment to 0.87 post-treatment. Dryness, the most prevalent symptom initially reported by 85.5% of participants, decreased to 53.8% after treatment. These findings suggest that vitamin E, as part of the Ozoile formulation, aids in alleviating various menopausal symptoms linked to genitourinary syndrome.

However, it's important to note that while Ozoile proved effective in easing symptoms, further studies are needed to isolate the specific contribution of vitamin E and compare it to other established treatments. This will help clarify its role in managing menopause symptoms more effectively.
Read More

Most Useful Reviews

9.5
Reduces hot flashes
This vitamin has been beneficial during menopause, helping with hormonal deficiency and night awakenings. It reduces hot flashes and enhances sexual desire. I took a high dose twice a week, but consult a doctor before using it.
Read More
9.5
Eases menopause symptoms
Excellent! I use vitamin E for menopause, as it alleviates the side effects. I no longer experience hot flashes, which makes me very happy.
Read More

Medical Researches

SCIENTIFIC SCORE
Most Likely Effective
Based on 3 Researches
8.3
9
Effectiveness of Ozoile Treatment
Stable Ozonides plus Vitamin E Acetate (Ozoile) for Treatment of Genitourinary Syndrome.
Limited significance in isolating vitamin E
We assessed the impact of a combination treatment using stable ozonides and vitamin E acetate, called Ozoile, on symptoms associated with genitourinary syndrome, commonly seen in menopause. This syndrome results from decreased estrogen levels, leading to discomfort in the genitourinary tract. Women experiencing symptoms like dryness, burning, and pain participated in our study over a period of 20 days.

The results were promising. We observed a significant reduction in pain, with the occurrence dropping from 16.7% to 11.8%. Additionally, the average intensity of symptoms showed a notable decrease—from 2.10 pre-treatment to 0.87 post-treatment. Dryness, the most prevalent symptom initially reported by 85.5% of participants, decreased to 53.8% after treatment. These findings suggest that vitamin E, as part of the Ozoile formulation, aids in alleviating various menopausal symptoms linked to genitourinary syndrome.

However, it's important to note that while Ozoile proved effective in easing symptoms, further studies are needed to isolate the specific contribution of vitamin E and compare it to other established treatments. This will help clarify its role in managing menopause symptoms more effectively.
Read More
8
Vitamin E enhances vaginal health
Retrospective Investigator-Initiated Trial on Tocopherol Acetate Vaginal Administration in Pre-and Postmenopausal Women.
Directly addresses menopause treatment
We examined how tocopherol acetate, commonly known as vitamin E, affects vaginal health in women experiencing menopause and those who are premenopausal. The study involved 50 women, split into two groups: 28 postmenopausal and 22 premenopausal, who were assessed before and after a two-week treatment with tocopherol acetate ovules.

After the treatment period, we observed significant improvements in the bothersome symptoms associated with vaginal atrophy, such as dryness, itching, and discomfort during intercourse. Participants reported a noticeable difference in their vaginal health post-treatment, which is quite encouraging. Additionally, a molecular analysis indicated a positive change in the vaginal microbiota, particularly among the premenopausal group, suggesting that vitamin E can help foster a healthier vaginal environment.

Overall, our findings support the potential benefits of using tocopherol acetate for enhancing vaginal well-being during menopause. This could offer a natural alternative for women seeking relief from menopausal symptoms, improving their quality of life during this transitional phase.
Read More
8
Vitamin E may improve menopausal mood
Ameliorative effect of α-tocopherol and tocotrienol-rich palm oil extract on menopause-associated mood disorder in ovariectomized mice.
Directly addresses vitamin E's effects
We evaluated the impact of vitamin E on mood disorders associated with menopause, particularly focusing on symptoms like anxiety and depression in a mouse model. The study involved ovariectomized mice to simulate estrogen deficiency, a key factor influencing menopause-related mood changes.

Our findings revealed that these mice exhibited behaviors typical of depression and anxiety, along with higher levels of corticosterone, a hormone linked to stress. We administered α-tocopherol (a form of vitamin E) and tocotrienol-rich palm oil extract over 14 days to see if they could alleviate these symptoms.

Remarkably, both treatments helped improve behavior in various tests designed to assess anxiety and depression. Notably, tocotrienol-rich palm oil extract showed additional benefits in mice subjected to chronic stress, effectively altering their emotional responses. Importantly, both treatments also led to reductions in elevated stress hormone levels.

These results suggest that vitamin E, through both α-tocopherol and tocotrienol-rich extracts, may help alleviate mood disorders linked to menopause by modulating the body's stress response. This could pave the way for new treatments to support women's psychological well-being during this challenging life stage.
Read More

User Reviews

USERS' SCORE
Excellent
Based on 2 Reviews
9.5
9.5
Reduces hot flashes
This vitamin has been beneficial during menopause, helping with hormonal deficiency and night awakenings. It reduces hot flashes and enhances sexual desire. I took a high dose twice a week, but consult a doctor before using it.
9.5
Eases menopause symptoms
Excellent! I use vitamin E for menopause, as it alleviates the side effects. I no longer experience hot flashes, which makes me very happy.
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