Selenium reduces acne in PCOSSelenium Supplementation and the Effects on Reproductive Outcomes, Biomarkers of Inflammation, and Oxidative Stress in Women with Polycystic Ovary Syndrome.
We examined how selenium supplementation impacts acne among women with polycystic ovary syndrome (PCOS) through a rigorous 8-week trial. In a randomized double-blind and placebo-controlled setup, we compared 32 women taking 200 μg of selenium daily against 32 taking a placebo.
Notably, those receiving selenium showed a significant drop in acne rates, from 12.5% in the placebo group to 46.9% in the selenium group. This indicates that selenium might indeed help reduce acne, alongside other reproductive and health improvements. However, some hormonal factors didn't show notable changes.
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Selenium temporarily aids acne improvementErythrocyte glutathione peroxidase activity in acne vulgaris and the effect of selenium and vitamin E treatment.
We examined the impact of selenium and vitamin E on acne by analyzing erythrocyte glutathione-peroxidase (GSH-Px) activity in 42 men and 47 women with varying degrees of acne.
While treatment with selenium showed promising improvements, particularly in pustular acne patients with low GSH-Px activity, the benefits were temporary. After 6-12 weeks of taking selenium and vitamin E, levels of GSH-Px returned to baseline about 6-8 weeks following treatment cessation.
Overall, while some individuals did experience positive results, significant long-term benefits were not established.
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Selenium's limited impact on acneSelenium levels and skin diseases: systematic review and meta-analysis.
We examined how selenium levels relate to acne and other skin diseases through a comprehensive review of 27 studies involving over 8,400 participants.
Our findings revealed that patients with acne and other conditions like psoriasis showed notably lower levels of selenium compared to healthy individuals.
However, while high selenium levels appeared protective for some skin diseases, there was no significant difference noted in selenium levels for acne patients versus controls.
Ultimately, this suggests that selenium’s role in acne may not be as impactful as previously thought.
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