In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
Most Useful Reviews
9
Cold and flu saver
Saves during colds and flu 👍👍😍
Read More
9
Faster recovery from flu
Zinc boosts the immune system against respiratory illnesses like flu or colds. It helps reduce recovery time if you have the flu or cold. These small tablets are easy to take daily with or without meals, and the quality packaging protects them from sunlight.
Read More
9
Medicine cabinet essential
Our saviour for flu and colds, we always have it in our medicine cabinet.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
Read More
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
Read More
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.1
All Reviews
Positive Reviews
Negative Reviews
9
Cold and flu saver
Saves during colds and flu 👍👍😍
Read More
9
Faster recovery from flu
Zinc boosts the immune system against respiratory illnesses like flu or colds. It helps reduce recovery time if you have the flu or cold. These small tablets are easy to take daily with or without meals, and the quality packaging protects them from sunlight.
Read More
9
Medicine cabinet essential
Our saviour for flu and colds, we always have it in our medicine cabinet.
Read More
9
Impressive health benefits
NOW is my family's favourite brand. The zinc I've used for quite some time has positively affected my health. Over the past year, I haven’t had the flu and during the Covid-19 pandemic, I wasn't infected. I take zinc along with vitamin D3 and K2. It's a dietary supplement that supports healthy skin, vision, and immune function, and my body feels really healthy.
Read More
7.5
Improved immune resilience
I'm glad to share the benefits I've experienced using Zinc Gluconate in the fight against viruses. Since incorporating this supplement into my routine, I've noticed a positive boost in my immune system's resilience. The properties of zinc gluconate seem to aid in supporting my body's ability to defend against viruses, contributing to a reduction in the duration and severity of colds. While I can't attribute everything solely to the supplement, I believe it's strengthening my immune response. It's become a staple for me, especially during cold and flu seasons, and I'm pleased with the potential benefits for my immune health.
The flu, short for influenza, is a contagious respiratory illness caused by influenza viruses. It affects the nose, throat, and sometimes the lungs, leading to a range of symptoms that can vary in severity. Common symptoms include fever, chills, muscle aches, cough, congestion, runny nose, headaches, and fatigue. The flu can lead to serious complications, particularly in vulnerable populations such as young children, the elderly, pregnant women, and those with underlying health conditions.
The flu virus spreads primarily through respiratory droplets when an infected person coughs, sneezes, or talks. It can also be transmitted by touching surfaces contaminated with the virus and then touching one's face. Vaccination is the most effective way to prevent the flu, and the vaccine is typically updated annually to provide protection against the most common circulating strains. In addition to vaccination, practicing good hygiene, such as frequent handwashing and respiratory etiquette, can help minimize the risk of infection.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential benefits in managing cold and flu symptoms, and there is some evidence to suggest that it may help reduce the severity and duration of these illnesses. Several clinical studies have indicated that zinc supplements can shorten the duration of cold symptoms if taken within the first 24 hours of their onset. While zinc may not necessarily prevent you from getting the flu, it could aid in alleviating symptoms and supporting your immune system during illness.
It's important to consider the appropriate dosage and consult with a healthcare provider before starting any supplementation, as excessive zinc intake can lead to adverse effects. Zinc lozenges and supplements can be helpful, but they should be part of a broader approach to flu prevention that includes vaccinations, maintaining a healthy lifestyle, and good hygiene practices. If you experience flu symptoms, it's always a good idea to consult a healthcare professional for tailored advice and treatment options.
Based on user reviews, individuals taking zinc supplements for flu and colds report varying timelines for noticeable results. Some users indicate that they experience a positive impact on their immune system's resilience relatively quickly, with benefits seen after just a few days of taking the supplement. One user mentioned that since incorporating zinc gluconate into their routine, they felt an immediate improvement in their ability to fend off viruses, contributing to a reduction in both duration and severity of colds (Read Review). Others noted that they have seen enhanced immunity and fewer occurrences of colds and flu within about a month of consistent use (Read Review).
Moreover, there are reports that taking zinc at the first signs of illness can significantly reduce the severity of symptoms. One user claimed that taking a tablet at the onset of flu symptoms led to a marked reduction in severity (Read Review). Generally, while some individuals may see benefits relatively quickly, others advocate for a more extended period (about 4 to 5 days) to witness substantial improvements in recovery time when combined with other vitamins (Read Review).
The use of zinc as a supplement to combat flu symptoms is gaining traction in scientific circles, backed by various studies. For instance, a study examining the benefits of gargling with a mouthwash containing zinc revealed that participants showed a 21.5% lower frequency and an 11% reduction in symptom severity related to upper respiratory issues when using the mouthwash compared to those who did not [1]. Furthermore, zinc has been linked to reducing the entry of the flu virus into cells, as demonstrated in research emphasizing its role in decreasing the expression of Cav1.2, a receptor crucial for viral entry [2].
Moreover, zinc's effectiveness may be strengthened when used in conjunction with natural compounds. A study showed that combining zinc with herbal polyphenols led to a remarkable 50-95% reduction in viral genome replication for various respiratory RNA viruses, including the flu [3]. Additional research highlighted that zinc’s immune-boosting properties could lower the severity of flu symptoms and support recovery, providing a rationale for its potential use in flu prevention strategies [5]. While existing studies demonstrate promising outcomes, the exact contributions of zinc when isolated from other treatments remain unclear, indicating that further research is warranted.
Based on user reviews, many individuals have reported significant improvements in their symptoms related to colds and flu after incorporating zinc supplements into their routines. Users frequently mention that zinc not only provides a supportive role in enhancing their immune systems but also shortens the duration and severity of illnesses. One user shared that since they started using zinc gluconate, they experienced a marked reduction in their body's vulnerability to viruses and attributed this to an overall boost in their immune resilience (Read Review). Additionally, another reviewer noted that zinc effectively reduced their recovery time from flu symptoms, highlighting its effectiveness as a preventative measure during cold and flu season (Read Review).
Furthermore, several users noted positive anecdotal experiences when combining zinc with other vitamins like D3 and C, with one expressing that this trio greatly increased their overall immunity and made them less susceptible to infections (Read Review). Others echoed similar sentiments, emphasizing that using the supplement at the first signs of illness significantly alleviated their symptoms, making it a staple in their households during flu season (Read Review, Read Review). While the results can vary among users, the shared experiences consistently suggest that zinc can play a crucial role in bolstering immune health.
Users report favorable experiences when combining zinc supplements with other vitamins for supporting immune health, especially during flu season. A recurring sentiment in the reviews highlights the effectiveness of a trio comprising zinc, vitamin C, and vitamin D. One reviewer noted that using this combination at the first signs of a cold or flu significantly enhanced their immune response and recommended it to others (Read Review). Additionally, another user elaborated on taking zinc alongside vitamin D and K2, stating that this practice positively impacted their overall health, especially during times when respiratory illnesses were prevalent (Read Review).
Moreover, several reviewers emphasized the role of zinc in reducing the severity and duration of symptoms when combined with other vitamins. One user mentioned that taking zinc at the onset of flu symptoms played a crucial role in significantly alleviating their symptoms (Read Review). Overall, the feedback suggests that users find zinc to be an essential part of their immune defense strategy, particularly when used in conjunction with other supportive vitamins during cold and flu season (Read Review). This combination is viewed as a reliable preventive measure, making it common among users' households during peak illness periods.
Based on user reviews, the right dose of zinc for treating the flu can vary, but many users report that around 50 mg is effective. For instance, one review stated that "Zinc 50 mg can be used at the first symptoms of colds, flu, or COVID for 4 to 5 days," noting that combining it with other vitamins can significantly reduce symptoms and speed up healing Read Review. Users also indicated that taking one tablet a day is common practice, as noted in another review where the user mentioned, "It knocks it out right away. Don't take more than one a day" Read Review.
Furthermore, some users highlight the importance of zinc in enhancing immune function during cold and flu seasons, suggesting that dosing should ideally be initiated at the first signs of illness. A user emphasized taking zinc alongside vitamin D at the onset of flu symptoms as effective Read Review. Overall, users are clear that sticking to one daily dose, particularly around the 50 mg level, can be beneficial without risking negative side effects associated with higher amounts.
7.5
Improved immune resilience
I'm glad to share the benefits I've experienced using Zinc Gluconate in the fight against viruses. Since incorporating this supplement into my routine, I've noticed a positive boost in my immune system's resilience. The properties of zinc gluconate seem to aid in supporting my body's ability to defend against viruses, contributing to a reduction in the duration and severity of colds. While I can't attribute everything solely to the supplement, I believe it's strengthening my immune response. It's become a staple for me, especially during cold and flu seasons, and I'm pleased with the potential benefits for my immune health.
7.5
Noticeable immunity improvement
A great supplement! After a month of taking it, I noticed an improvement in my immunity. I encountered colds and flu less often. I recommend taking it during the cold season, and it's best to consult your doctor beforehand.
7.5
Reduced flu severity
Helps support the immune system. I took one tablet at the onset of the flu, and it significantly reduced the severity of my symptoms.
7.5
Fast symptom relief
Great product; the SOLGAR brand is a safe brand with quality ingredients. I have confidence in using it. Zinc 50 mg can be used at the first symptoms of colds, flu, or COVID for 4 to 5 days. Combined with other vitamins, it reduces symptoms and speeds healing.
9
Faster recovery from flu
Zinc boosts the immune system against respiratory illnesses like flu or colds. It helps reduce recovery time if you have the flu or cold. These small tablets are easy to take daily with or without meals, and the quality packaging protects them from sunlight.
9
Highly effective trio
I always keep vitamin C, zinc, and vitamin D in my medicine cabinet. I use this trio at the first signs of a cold or flu. These supplements are very effective, and I recommend them to everyone.
9
Medicine cabinet essential
Our saviour for flu and colds, we always have it in our medicine cabinet.
7.5
Family flu defence
We take it with the whole family during flu and colds, especially for those with ear infections, sore throats, pharyngitis, and otitis media.
9
Impressive health benefits
NOW is my family's favourite brand. The zinc I've used for quite some time has positively affected my health. Over the past year, I haven’t had the flu and during the Covid-19 pandemic, I wasn't infected. I take zinc along with vitamin D3 and K2. It's a dietary supplement that supports healthy skin, vision, and immune function, and my body feels really healthy.
9
Quick flu relief
This is a perfect dosage to deal with any colds or flu that someone feels. It knocks it out right away. Don't take more than one a day.
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
9
Zinc and flavonoids combat flu
Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
References
Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. doi:10.1371/journal.pone.0316807
Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. doi:10.21873/invivo.12967
Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. doi:10.3390/ph15030377
Nakashima A, Horio Y, Suzuki K, Isegawa Y. Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus. Nutrients. 2021;13. doi:10.3390/nu13113911
Sadeghsoltani F, Mohammadzadeh I, Safari MM, Hassanpour P, Izadpanah M, et al. Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation. Biol Trace Elem Res. 2022;200:2556. doi:10.1007/s12011-021-02859-z